KEGG   PATHWAY: cgib00830
Entry
cgib00830                   Pathway                                
Name
Retinol metabolism - Carassius gibelio (silver crucian carp)
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
cgib00830  Retinol metabolism
cgib00830

Other DBs
GO: 0006776
Organism
Carassius gibelio (silver crucian carp) [GN:cgib]
Gene
127962425  beta,beta-carotene 15,15'-dioxygenase [KO:K00515] [EC:1.13.11.63]
127962426  beta,beta-carotene 15,15'-dioxygenase [KO:K00515] [EC:1.13.11.63]
128016523  beta,beta-carotene 15,15'-dioxygenase-like [KO:K00515] [EC:1.13.11.63]
127971450  alcohol dehydrogenase class-3 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
127971510  zgc:77938; alcohol dehydrogenase class-3-like [KO:K00121] [EC:1.1.1.284 1.1.1.1]
127971511  alcohol dehydrogenase class-3-like isoform X1 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
127934282  alcohol dehydrogenase 1-like [KO:K00121] [EC:1.1.1.284 1.1.1.1]
127970195  alcohol dehydrogenase 1-like [KO:K00121] [EC:1.1.1.284 1.1.1.1]
127970196  alcohol dehydrogenase 1-like [KO:K00121] [EC:1.1.1.284 1.1.1.1]
128026349  alcohol dehydrogenase 1-like [KO:K00121] [EC:1.1.1.284 1.1.1.1]
128027309  alcohol dehydrogenase class-3-like [KO:K00121] [EC:1.1.1.284 1.1.1.1]
128027495  alcohol dehydrogenase class-3-like [KO:K00121] [EC:1.1.1.284 1.1.1.1]
127945187  short-chain dehydrogenase/reductase 3-like [KO:K11146] [EC:1.1.1.300]
127967727  short-chain dehydrogenase/reductase 3-like [KO:K11146] [EC:1.1.1.300]
128022245  short-chain dehydrogenase/reductase 3-like [KO:K11146] [EC:1.1.1.300]
128011309  short-chain dehydrogenase/reductase 3-like [KO:K11146] [EC:1.1.1.300]
127961798  dehydrogenase/reductase SDR family member 4 [KO:K11147] [EC:1.1.-.-]
128017141  dehydrogenase/reductase SDR family member 4-like [KO:K11147] [EC:1.1.-.-]
127951840  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
127952005  zmp:0000001048; retinol dehydrogenase 8 isoform X1 [KO:K11150] [EC:1.1.1.-]
127952944  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
127952953  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
127949521  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
127949522  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
127960116  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
128015106  zgc:109982; retinol dehydrogenase 8 [KO:K11150] [EC:1.1.1.-]
128030612  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
127946050  retinol dehydrogenase 10-A [KO:K11151] [EC:1.1.1.-]
127950754  retinol dehydrogenase 10-B [KO:K11151] [EC:1.1.1.-]
128013662  retinol dehydrogenase 10-A-like [KO:K11151] [EC:1.1.1.-]
127962532  si:ch211-107o10.3; retinol dehydrogenase 11 [KO:K11153] [EC:1.1.1.300]
127945886  retinol dehydrogenase 12-like isoform X1 [KO:K11153] [EC:1.1.1.300]
127974743  si:dkey-23o4.6; retinol dehydrogenase 13 [KO:K11153] [EC:1.1.1.300]
127950760  si:dkey-94e7.2; retinol dehydrogenase 12 isoform X1 [KO:K11153] [EC:1.1.1.300]
127970104  retinol dehydrogenase 11-like [KO:K11153] [EC:1.1.1.300]
127978730  zgc:153441; retinol-DH_like_SDR_c domain-containing protein [KO:K11153] [EC:1.1.1.300]
128013349  retinol dehydrogenase 12-like isoform X1 [KO:K11153] [EC:1.1.1.300]
128026092  retinol dehydrogenase 11-like [KO:K11153] [EC:1.1.1.300]
128016980  retinol dehydrogenase 11-like [KO:K11153] [EC:1.1.1.300]
128013144  si:dkey-73n8.3; retinol dehydrogenase 12 [KO:K11153] [EC:1.1.1.300]
128013145  zgc:112332; retinol dehydrogenase 12 isoform X1 [KO:K11153] [EC:1.1.1.300]
127961375  epidermal retinol dehydrogenase 2 [KO:K15734] [EC:1.1.1.105]
127984303  si:dkey-221h15.4; epidermal retinol dehydrogenase 2 [KO:K15734] [EC:1.1.1.105]
127980198  lecithin retinol acyltransferase-like [KO:K00678] [EC:2.3.1.135]
127952665  lecithin retinol acyltransferase-like [KO:K00678] [EC:2.3.1.135]
127948524  lecithin retinol acyltransferase [KO:K00678] [EC:2.3.1.135]
127948525  lecithin retinol acyltransferase b, tandem duplicate 2 [KO:K00678] [EC:2.3.1.135]
127949611  lecithin retinol acyltransferase-like [KO:K00678] [EC:2.3.1.135]
127979143  diacylglycerol O-acyltransferase 1-like [KO:K11155] [EC:2.3.1.20 2.3.1.75 2.3.1.76]
127975172  diacylglycerol O-acyltransferase 1b [KO:K11155] [EC:2.3.1.20 2.3.1.75 2.3.1.76]
127935312  diacylglycerol O-acyltransferase 1-like [KO:K11155] [EC:2.3.1.20 2.3.1.75 2.3.1.76]
128031080  diacylglycerol O-acyltransferase 1-like [KO:K11155] [EC:2.3.1.20 2.3.1.75 2.3.1.76]
128011052  diacylglycerol O-acyltransferase 1-like [KO:K11155] [EC:2.3.1.20 2.3.1.75 2.3.1.76]
127949082  LOW QUALITY PROTEIN: patatin-like phospholipase domain-containing protein 4 [KO:K11157] [EC:3.1.1.-]
128015887  patatin-like phospholipase domain-containing protein 4 [KO:K11157] [EC:3.1.1.-]
127951348  retinoid isomerohydrolase [KO:K11158] [EC:3.1.1.64 5.3.3.22]
127964249  retinal Mueller cells isomerohydrolase [KO:K11158] [EC:3.1.1.64 5.3.3.22]
128018068  retinal Mueller cells isomerohydrolase-like [KO:K11158] [EC:3.1.1.64 5.3.3.22]
127942941  retinol dehydrogenase 7-like [KO:K00061] [EC:1.1.1.315]
127986955  retinol dehydrogenase 7-like [KO:K00061] [EC:1.1.1.315]
127942713  aldehyde oxidase 6 [KO:K00157] [EC:1.2.3.1]
127987425  aldehyde oxidase 5 [KO:K00157] [EC:1.2.3.1]
127962147  retinal dehydrogenase 2 [KO:K07249] [EC:1.2.1.36]
127961291  aldehyde dehydrogenase family 1 member A3 [KO:K07249] [EC:1.2.1.36]
128016974  retinal dehydrogenase 2-like [KO:K07249] [EC:1.2.1.36]
128017389  aldehyde dehydrogenase family 1 member A3-like [KO:K07249] [EC:1.2.1.36]
127968914  cytochrome P450 26A1 [KO:K07437] [EC:1.14.14.-]
128024976  cytochrome P450 26A1-like [KO:K07437] [EC:1.14.14.-]
127961167  cytochrome P450 26B1-like [KO:K12664] [EC:1.14.14.-]
128017097  cytochrome P450 26B1 [KO:K12664] [EC:1.14.14.-]
127933465  cytochrome P450 26B1-like [KO:K12665] [EC:1.14.14.-]
127976006  cytochrome P450 26B1 [KO:K12665] [EC:1.14.14.-]
127951781  cytochrome P450 3A30 [KO:K07424] [EC:1.14.14.1]
127951782  cytochrome P450 3A30-like [KO:K07424] [EC:1.14.14.1]
127949467  cytochrome P450 3A30-like isoform X1 [KO:K07424] [EC:1.14.14.1]
127949468  cytochrome P450 3A30-like [KO:K07424] [EC:1.14.14.1]
128018251  cytochrome P450 3A30-like [KO:K07424] [EC:1.14.14.1]
127963576  UDP glucuronosyltransferase 5 family, polypeptide E1 [KO:K00699] [EC:2.4.1.17]
127983785  UDP-glucuronosyltransferase 2C1-like [KO:K00699] [EC:2.4.1.17]
127965067  UDP-glucuronosyltransferase-like isoform X1 [KO:K00699] [EC:2.4.1.17]
127945932  UDP-glucuronosyltransferase 2A2-like [KO:K00699] [EC:2.4.1.17]
127934383  UDP glucuronosyltransferase 5 family, polypeptide F1 [KO:K00699] [EC:2.4.1.17]
127946746  UDP-glucuronosyltransferase 2A3-like isoform X1 [KO:K00699] [EC:2.4.1.17]
127966413  UDP glucuronosyltransferase 5 family, polypeptide D1 [KO:K00699] [EC:2.4.1.17]
127957849  UDP glucuronosyltransferase 2 family, polypeptide B6 isoform X1 [KO:K00699] [EC:2.4.1.17]
127948591  UDP-glucuronosyltransferase 2C1-like isoform X1 [KO:K00699] [EC:2.4.1.17]
127948593  UDP-glucuronosyltransferase 2A3-like [KO:K00699] [EC:2.4.1.17]
127958781  UDP-glucuronosyltransferase 2A1-like [KO:K00699] [EC:2.4.1.17]
127968247  UDP-glucuronosyltransferase 1-6-like isoform X1 [KO:K00699] [EC:2.4.1.17]
127968249  UDP-glucuronosyltransferase 1-6-like [KO:K00699] [EC:2.4.1.17]
127961342  UDP-glucuronosyltransferase 2B31-like [KO:K00699] [EC:2.4.1.17]
128021231  UDP glucuronosyltransferase 5 family, polypeptide G2 [KO:K00699] [EC:2.4.1.17]
128014293  UDP-glucuronosyltransferase 2A1-like isoform X1 [KO:K00699] [EC:2.4.1.17]
128014294  UDP-glucuronosyltransferase 2C1-like [KO:K00699] [EC:2.4.1.17]
128014523  UDP-glucuronosyltransferase 2C1-like isoform X1 [KO:K00699] [EC:2.4.1.17]
128022217  UDP-glucuronosyltransferase 1-6-like isoform X1 [KO:K00699] [EC:2.4.1.17]
128017171  UDP glucuronosyltransferase 5 family, polypeptide G1 [KO:K00699] [EC:2.4.1.17]
127990013  UDP-glucuronosyltransferase 2C1-like isoform X1 [KO:K00699] [EC:2.4.1.17]
127990069  UDP-glucuronosyltransferase 2A1-like [KO:K00699] [EC:2.4.1.17]
127990085  UDP-glucuronosyltransferase 2A1-like isoform X1 [KO:K00699] [EC:2.4.1.17]
128018871  UDP-glucuronosyltransferase 2A1-like [KO:K00699] [EC:2.4.1.17]
128019681  UDP-glucuronosyltransferase-like isoform X1 [KO:K00699] [EC:2.4.1.17]
127951632  all-trans-retinol 13,14-reductase [KO:K09516] [EC:1.3.99.23]
127964335  inactive all-trans-retinol 13,14-reductase-like [KO:K09516] [EC:1.3.99.23]
127964337  inactive all-trans-retinol 13,14-reductase-like isoform X1 [KO:K09516] [EC:1.3.99.23]
128025087  si:ch1073-13h15.3; inactive all-trans-retinol 13,14-reductase [KO:K09516] [EC:1.3.99.23]
128020108  inactive all-trans-retinol 13,14-reductase-like [KO:K09516] [EC:1.3.99.23]
127959176  cytochrome P450 27C1 [KO:K17951] [EC:1.14.19.53]
128016160  cytochrome P450 27C1-like [KO:K17951] [EC:1.14.19.53]
Compound
C00376  Retinal
C00473  Retinol
C00777  Retinoate
C00778  Rhodopsin
C00899  11-cis-Retinol
C02075  Retinyl ester
C02094  beta-Carotene
C02110  11-cis-Retinal
C02588  Retinyl palmitate
C03455  11-cis-Retinyl palmitate
C05914  Bathorhodopsin
C05915  Lumirhodopsin
C05916  Metarhodopsin
C05917  Iodopsin
C11061  all-trans-Retinoyl-beta-glucuronide
C15492  all-trans-13,14-Dihydroretinol
C15493  9-cis-Retinoic acid
C16677  all-trans-4-Hydroxyretinoic acid
C16678  all-trans-4-Oxoretinoic acid
C16679  all-trans-18-Hydroxyretinoic acid
C16680  all-trans-5,6-Epoxyretinoic acid
C16681  9-cis-Retinal
C16682  9-cis-Retinol
C16683  4-Oxoretinol
C21797  all-trans-3,4-Didehydroretinol
Reference
PMID:16968212
  Authors
Travis GH, Golczak M, Moise AR, Palczewski K.
  Title
Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents.
  Journal
Annu Rev Pharmacol Toxicol 47:469-512 (2007)
DOI:10.1146/annurev.pharmtox.47.120505.105225
Reference
PMID:17618621
  Authors
Muniz A, Villazana-Espinoza ET, Hatch AL, Trevino SG, Allen DM, Tsin AT.
  Title
A novel cone visual cycle in the cone-dominated retina.
  Journal
Exp Eye Res 85:175-84 (2007)
DOI:10.1016/j.exer.2007.05.003
Reference
PMID:11093772
  Authors
Marill J, Cresteil T, Lanotte M, Chabot GG.
  Title
Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites.
  Journal
Mol Pharmacol 58:1341-8 (2000)
DOI:10.1124/mol.58.6.1341
Reference
PMID:17893666
  Authors
Nezzar H, Chiambaretta F, Marceau G, Blanchon L, Faye B, Dechelotte P, Rigal D, Sapin V.
  Title
Molecular and metabolic retinoid pathways in the human ocular surface.
  Journal
Mol Vis 13:1641-50 (2007)
Reference
PMID:16688755
  Authors
Blomhoff R, Blomhoff HK.
  Title
Overview of retinoid metabolism and function.
  Journal
J Neurobiol 66:606-30 (2006)
DOI:10.1002/neu.20242
Reference
PMID:16428379
  Authors
Liden M, Eriksson U.
  Title
Understanding retinol metabolism: structure and function of retinol dehydrogenases.
  Journal
J Biol Chem 281:13001-4 (2006)
DOI:10.1074/jbc.R500027200
KO pathway
ko00830   
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