KEGG   PATHWAY: cpla00830
Entry
cpla00830                   Pathway                                
Name
Retinol metabolism - Chiloscyllium plagiosum (whitespotted bambooshark)
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
cpla00830  Retinol metabolism
cpla00830

Other DBs
GO: 0006776
Organism
Chiloscyllium plagiosum (whitespotted bambooshark) [GN:cpla]
Gene
122558277  beta,beta-carotene 15,15'-dioxygenase-like [KO:K00515] [EC:1.13.11.63]
122539510  alcohol dehydrogenase class-3 isoform X1 [KO:K00121] [EC:1.1.1.284 1.1.1.1]
122540237  short-chain dehydrogenase/reductase 3-like [KO:K11146] [EC:1.1.1.300]
122544221  dehydrogenase/reductase SDR family member 4-like [KO:K11147] [EC:1.1.-.-]
122545310  dehydrogenase/reductase SDR family member 4-like [KO:K11147] [EC:1.1.-.-]
122546597  dehydrogenase/reductase SDR family member 4-like [KO:K11147] [EC:1.1.-.-]
122551657  dehydrogenase/reductase SDR family member 9-like isoform X1 [KO:K11149] [EC:1.1.-.-]
122554184  zgc:109982; retinol dehydrogenase 8 isoform X1 [KO:K11150] [EC:1.1.1.-]
122552258  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
122552259  retinol dehydrogenase 8-like [KO:K11150] [EC:1.1.1.-]
122549517  rdh10a; retinol dehydrogenase 10-A [KO:K11151] [EC:1.1.1.-]
122553717  rdh12; retinol dehydrogenase 12 [KO:K11153] [EC:1.1.1.300]
122549919  retinol dehydrogenase 12-like [KO:K11153] [EC:1.1.1.300]
122540832  retinol dehydrogenase 12-like [KO:K11153] [EC:1.1.1.300]
122553002  retinol dehydrogenase 13-like isoform X1 [KO:K11161] [EC:1.1.1.300]
122549479  sdr16c5b; epidermal retinol dehydrogenase 2 [KO:K15734] [EC:1.1.1.105]
122553730  lecithin retinol acyltransferase-like [KO:K00678] [EC:2.3.1.135]
122550344  diacylglycerol O-acyltransferase 1-like [KO:K11155] [EC:2.3.1.20 2.3.1.75 2.3.1.76]
122558555  diacylglycerol O-acyltransferase 1-like [KO:K11155] [EC:2.3.1.20 2.3.1.75 2.3.1.76]
122550931  pnpla4; patatin-like phospholipase domain-containing protein 4 isoform X1 [KO:K11157] [EC:3.1.1.-]
122554402  retinoid isomerohydrolase-like [KO:K11158] [EC:3.1.1.64 5.3.3.22]
122543285  rdh5; retinol dehydrogenase 5 [KO:K00061] [EC:1.1.1.315]
122551442  aldehyde oxidase 2-like [KO:K00157] [EC:1.2.3.1]
122560880  retinal dehydrogenase 1-like isoform X1 [KO:K07249] [EC:1.2.1.36]
122541017  retinal dehydrogenase 2 [KO:K07249] [EC:1.2.1.36]
122541105  aldh1a3; aldehyde dehydrogenase family 1 member A3 isoform X1 [KO:K07249] [EC:1.2.1.36]
122561092  cytochrome P450 26A1 isoform X1 [KO:K07437] [EC:1.14.14.-]
122549869  cytochrome P450 26B1 isoform X1 [KO:K12664] [EC:1.14.14.-]
122556960  cytochrome P450 26B1-like [KO:K12664] [EC:1.14.14.-]
122561093  cytochrome P450 26B1-like isoform X1 [KO:K12665] [EC:1.14.14.-]
122542870  cytochrome P450 2C42-like isoform X1 [KO:K07413] [EC:1.14.14.1]
122560449  cytochrome P450 3A21-like [KO:K07424] [EC:1.14.14.1]
122560798  cytochrome P450 3A21-like [KO:K07424] [EC:1.14.14.1]
122560799  cytochrome P450 3A21-like [KO:K07424] [EC:1.14.14.1]
122541976  cytochrome P450 3A24-like [KO:K07424] [EC:1.14.14.1]
122556861  UDP-glucuronosyltransferase 2C1-like [KO:K00699] [EC:2.4.1.17]
122540942  UDP-glucuronosyltransferase 2A2-like [KO:K00699] [EC:2.4.1.17]
122540943  UDP-glucuronosyltransferase 1-2-like [KO:K00699] [EC:2.4.1.17]
122540944  UDP-glucuronosyltransferase 2A1-like [KO:K00699] [EC:2.4.1.17]
122540945  UDP-glucuronosyltransferase 2A1-like isoform X1 [KO:K00699] [EC:2.4.1.17]
122540946  UDP-glucuronosyltransferase 2C1-like [KO:K00699] [EC:2.4.1.17]
122540948  UDP-glucuronosyltransferase 2A1-like [KO:K00699] [EC:2.4.1.17]
122551392  UDP-glucuronosyltransferase 1A1-like [KO:K00699] [EC:2.4.1.17]
122551393  UDP-glucuronosyltransferase 1A1-like [KO:K00699] [EC:2.4.1.17]
122565115  ugt2a5; UDP glucuronosyltransferase 2 family, polypeptide A5 isoform X1 [KO:K00699] [EC:2.4.1.17]
122542355  UDP-glucuronosyltransferase 2C1-like isoform X1 [KO:K00699] [EC:2.4.1.17]
122539900  all-trans-retinol 13,14-reductase-like [KO:K09516] [EC:1.3.99.23]
122539909  all-trans-retinol 13,14-reductase-like isoform X1 [KO:K09516] [EC:1.3.99.23]
122551942  LOW QUALITY PROTEIN: cytochrome P450 27C1-like [KO:K17951] [EC:1.14.19.53]
Compound
C00376  Retinal
C00473  Retinol
C00777  Retinoate
C00778  Rhodopsin
C00899  11-cis-Retinol
C02075  Retinyl ester
C02094  beta-Carotene
C02110  11-cis-Retinal
C02588  Retinyl palmitate
C03455  11-cis-Retinyl palmitate
C05914  Bathorhodopsin
C05915  Lumirhodopsin
C05916  Metarhodopsin
C05917  Iodopsin
C11061  all-trans-Retinoyl-beta-glucuronide
C15492  all-trans-13,14-Dihydroretinol
C15493  9-cis-Retinoic acid
C16677  all-trans-4-Hydroxyretinoic acid
C16678  all-trans-4-Oxoretinoic acid
C16679  all-trans-18-Hydroxyretinoic acid
C16680  all-trans-5,6-Epoxyretinoic acid
C16681  9-cis-Retinal
C16682  9-cis-Retinol
C16683  4-Oxoretinol
C21797  all-trans-3,4-Didehydroretinol
Reference
PMID:16968212
  Authors
Travis GH, Golczak M, Moise AR, Palczewski K.
  Title
Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents.
  Journal
Annu Rev Pharmacol Toxicol 47:469-512 (2007)
DOI:10.1146/annurev.pharmtox.47.120505.105225
Reference
PMID:17618621
  Authors
Muniz A, Villazana-Espinoza ET, Hatch AL, Trevino SG, Allen DM, Tsin AT.
  Title
A novel cone visual cycle in the cone-dominated retina.
  Journal
Exp Eye Res 85:175-84 (2007)
DOI:10.1016/j.exer.2007.05.003
Reference
PMID:11093772
  Authors
Marill J, Cresteil T, Lanotte M, Chabot GG.
  Title
Identification of human cytochrome P450s involved in the formation of all-trans-retinoic acid principal metabolites.
  Journal
Mol Pharmacol 58:1341-8 (2000)
DOI:10.1124/mol.58.6.1341
Reference
PMID:17893666
  Authors
Nezzar H, Chiambaretta F, Marceau G, Blanchon L, Faye B, Dechelotte P, Rigal D, Sapin V.
  Title
Molecular and metabolic retinoid pathways in the human ocular surface.
  Journal
Mol Vis 13:1641-50 (2007)
Reference
PMID:16688755
  Authors
Blomhoff R, Blomhoff HK.
  Title
Overview of retinoid metabolism and function.
  Journal
J Neurobiol 66:606-30 (2006)
DOI:10.1002/neu.20242
Reference
PMID:16428379
  Authors
Liden M, Eriksson U.
  Title
Understanding retinol metabolism: structure and function of retinol dehydrogenases.
  Journal
J Biol Chem 281:13001-4 (2006)
DOI:10.1074/jbc.R500027200
KO pathway
ko00830   
LinkDB

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