KEGG   PATHWAY: cvf03083
Entry
cvf03083                    Pathway                                
Name
Polycomb repressive complex - Charadrius vociferus (killdeer)
Class
Genetic Information Processing; Chromosome
Pathway map
cvf03083  Polycomb repressive complex
cvf03083

Organism
Charadrius vociferus (killdeer) [GN:cvf]
Gene
104281520  CBX3; chromobox protein homolog 3 isoform X1 [KO:K11586]
104281629  AEBP2; zinc finger protein AEBP2 [KO:K17452]
104282060  [KO:K11488]
104282086  L3MBTL3; lethal(3)malignant brain tumor-like protein 3 [KO:K24387]
104282156  SUZ12; polycomb protein SUZ12 [KO:K11463]
104282208  KDM2B; lysine-specific demethylase 2B [KO:K10276] [EC:1.14.11.27]
104282694  CBX8; chromobox protein homolog 8 [KO:K11455]
104282763  YAF2; YY1-associated factor 2 [KO:K11468]
104282974  ASXL3; putative Polycomb group protein ASXL3 [KO:K11471]
104283061  EED; polycomb protein EED [KO:K11462]
104283444  PCGF6; polycomb group RING finger protein 6 [KO:K11470]
104283554  OGT; LOW QUALITY PROTEIN: UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit [KO:K09667] [EC:2.4.1.255]
104283669  CBX7; chromobox protein homolog 7 [KO:K11454]
104283724  CREBBP; LOW QUALITY PROTEIN: CREB-binding protein [KO:K04498] [EC:2.3.1.48]
104284345  PCGF2; polycomb group RING finger protein 2 [KO:K11460]
104284425  RBBP4; histone-binding protein RBBP4 [KO:K10752]
104284546  [KO:K26259]
104284553  USP7; ubiquitin carboxyl-terminal hydrolase 7 [KO:K11838] [EC:3.4.19.12]
104284606  SFMBT2; scm-like with four MBT domains protein 2 [KO:K26269]
104285183  RYBP; LOW QUALITY PROTEIN: RING1 and YY1-binding protein [KO:K11469]
104285379  DCAF7; DDB1- and CUL4-associated factor 7 [KO:K11805]
104285684  JARID2; protein Jumonji [KO:K11478]
104285857  RNF2; E3 ubiquitin-protein ligase RING2 [KO:K10695] [EC:2.3.2.27]
104285919  PHC3; polyhomeotic-like protein 3 [KO:K11458]
104285997  HDAC1; histone deacetylase 1 [KO:K06067] [EC:3.5.1.98]
104286137  RBBP7; histone-binding protein RBBP7 [KO:K11659]
104286145  SCML2; sex comb on midleg-like protein 2 [KO:K11465]
104286178  MTF2; metal-response element-binding transcription factor 2 isoform X1 [KO:K11485]
104286861  UBE2D3; ubiquitin-conjugating enzyme E2 D3 isoform X1 [KO:K06689] [EC:2.3.2.23]
104286986  UBE2D1; ubiquitin-conjugating enzyme E2 D1 isoform X1 [KO:K06689] [EC:2.3.2.23]
104287211  TEX10; LOW QUALITY PROTEIN: testis-expressed sequence 10 protein [KO:K14827]
104287547  KDM2A; lysine-specific demethylase 2A [KO:K10276] [EC:1.14.11.27]
104287611  L3MBTL1; lethal(3)malignant brain tumor-like protein 1 [KO:K24387]
104287629  MBD5; LOW QUALITY PROTEIN: methyl-CpG-binding domain protein 5 [KO:K23219]
104288087  CBX4; E3 SUMO-protein ligase CBX4 [KO:K11452] [EC:2.3.2.-]
104288356  [KO:K11459]
104288810  LCOR; ligand-dependent corepressor [KO:K26260]
104288835  [KO:K26260]
104289196  FBRSL1; fibrosin-1-like protein [KO:K26254]
104289398  [KO:K24387]
104289434  BCOR; BCL-6 corepressor [KO:K23215]
104289709  PCGF5; polycomb group RING finger protein 5 [KO:K11489]
104289744  FOXK2; forkhead box protein K2 [KO:K09404]
104289852  AUTS2; autism susceptibility gene 2 protein [KO:K23214]
104289982  USP45; ubiquitin carboxyl-terminal hydrolase 45 [KO:K11844] [EC:3.4.19.12]
104290375  [KO:K11479] [EC:2.7.11.1]
104290645  E2F6; transcription factor E2F6 [KO:K09390]
104290890  FOXK1; forkhead box protein K1 [KO:K09404]
104291172  ASXL2; LOW QUALITY PROTEIN: putative Polycomb group protein ASXL2 [KO:K11471]
104291457  UBE2D2; ubiquitin-conjugating enzyme E2 D2 [KO:K06689] [EC:2.3.2.23]
104291610  SKP1; S-phase kinase-associated protein 1 [KO:K03094]
104291792  YY1; transcriptional repressor protein YY1 [KO:K09201]
104291942  SFMBT1; scm-like with four MBT domains protein 1 [KO:K26269]
104291964  BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 [KO:K08588] [EC:3.4.19.12]
104292331  MBD6; methyl-CpG-binding domain protein 6 [KO:K26585]
104292712  TFDP1; transcription factor Dp-1 isoform X1 [KO:K04683]
104292830  WDR5; WD repeat-containing protein 5 [KO:K14963]
104292914  PHF19; PHD finger protein 19 [KO:K11486]
104292940  BCORL1; BCL-6 corepressor-like protein 1 [KO:K26199]
104293492  SCMH1; polycomb protein SCMH1 [KO:K11461]
104293856  ASXL1; putative Polycomb group protein ASXL1 [KO:K11471]
104294051  HDAC2; histone deacetylase 2 isoform X1 [KO:K06067] [EC:3.5.1.98]
104294506  PHC1; polyhomeotic-like protein 1 [KO:K11456]
104295188  USP16; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 16 [KO:K11844] [EC:3.4.19.12]
104295308  EZH2; histone-lysine N-methyltransferase EZH2 isoform X1 [KO:K11430] [EC:2.1.1.356]
104295331  PCGF3; polycomb group RING finger protein 3 [KO:K11488]
104295343  EZH1; histone-lysine N-methyltransferase EZH1 [KO:K17451] [EC:2.1.1.356]
104295488  L3MBTL2; lethal(3)malignant brain tumor-like protein 2 [KO:K24387]
104295489  EP300; LOW QUALITY PROTEIN: histone acetyltransferase p300 [KO:K04498] [EC:2.3.1.48]
104295911  MGA; MAX gene-associated protein [KO:K23399]
Reference
  Authors
Richly H, Aloia L, Di Croce L
  Title
Roles of the Polycomb group proteins in stem cells and cancer.
  Journal
Cell Death Dis 2:e204 (2011)
DOI:10.1038/cddis.2011.84
Reference
  Authors
Chittock EC, Latwiel S, Miller TC, Muller CW
  Title
Molecular architecture of polycomb repressive complexes.
  Journal
Biochem Soc Trans 45:193-205 (2017)
DOI:10.1042/BST20160173
Reference
  Authors
Geng Z, Gao Z
  Title
Mammalian PRC1 Complexes: Compositional Complexity and Diverse Molecular Mechanisms.
  Journal
Int J Mol Sci 21:ijms21228594 (2020)
DOI:10.3390/ijms21228594
Reference
  Authors
Kim JJ, Kingston RE
  Title
Context-specific Polycomb mechanisms in development.
  Journal
Nat Rev Genet 23:680-695 (2022)
DOI:10.1038/s41576-022-00499-0
Reference
  Authors
Dong GJ, Xu JL, Qi YR, Yuan ZQ, Zhao W
  Title
Critical Roles of Polycomb Repressive Complexes in Transcription and Cancer.
  Journal
Int J Mol Sci 23:ijms23179574 (2022)
DOI:10.3390/ijms23179574
Reference
  Authors
Ryan CW, Peirent ER, Regan SL, Guxholli A, Bielas SL
  Title
H2A monoubiquitination: insights from human genetics and animal models.
  Journal
Hum Genet 10.1007/s00439-023-02557-x (2023)
DOI:10.1007/s00439-023-02557-x
KO pathway
ko03083   

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