KEGG   PATHWAY: dsp04612
Entry
dsp04612                    Pathway                                
Name
Antigen processing and presentation - Dipodomys spectabilis (banner-tailed kangaroo rat)
Class
Organismal Systems; Immune system
Pathway map
dsp04612  Antigen processing and presentation
dsp04612

Other DBs
GO: 0019885 0019886 0042591
Organism
Dipodomys spectabilis (banner-tailed kangaroo rat) [GN:dsp]
Gene
122100316  Calr; calreticulin [KO:K08057]
122100834  Rfxank; DNA-binding protein RFXANK isoform X1 [KO:K08062]
122100859  Ifi30; gamma-interferon-inducible lysosomal thiol reductase [KO:K08059]
122101518  Hsp90ab1; heat shock protein HSP 90-beta [KO:K04079]
122101554  Nfya; nuclear transcription factor Y subunit alpha isoform X1 [KO:K08064]
122101946  Cd4; T-cell surface glycoprotein CD4 [KO:K06454]
122102830  Tapbpl; LOW QUALITY PROTEIN: tapasin-related protein [KO:K28445]
122103102  Psme3; proteasome activator complex subunit 3 [KO:K06698]
122104918  Nfyc; nuclear transcription factor Y subunit gamma isoform X1 [KO:K08066]
122106128  [KO:K08057]
122107037  Hspa5; endoplasmic reticulum chaperone BiP [KO:K09490] [EC:3.6.4.10]
122107322  Creb1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
122109148  Rfx5; DNA-binding protein RFX5 [KO:K08061]
122109432  Ctss; cathepsin S isoform X1 [KO:K01368] [EC:3.4.22.27]
122110045  Hspa2; heat shock-related 70 kDa protein 2 [KO:K26598]
122110292  Hspa8; heat shock cognate 71 kDa protein [KO:K03283]
122111099  [KO:K06752]
122111100  [KO:K06752]
122111152  [KO:K06752]
122111153  [KO:K06752]
122111154  [KO:K06752]
122111155  [KO:K06752]
122111156  [KO:K06752]
122111157  [KO:K06752]
122111160  [KO:K06752]
122111281  Tnf; tumor necrosis factor isoform X1 [KO:K03156]
122111313  [KO:K06751]
122111314  [KO:K06751]
122111316  [KO:K06751]
122111318  [KO:K06751]
122111319  [KO:K06751]
122111320  [KO:K06751]
122111321  [KO:K06751]
122111322  [KO:K06751]
122111324  [KO:K06751]
122111325  [KO:K06751]
122111326  [KO:K06751]
122111352  [KO:K06752]
122111353  [KO:K06752]
122111413  [KO:K08058]
122111476  Hspa1a; heat shock 70 kDa protein 1A [KO:K03283]
122111481  Tap1; antigen peptide transporter 1 [KO:K05653] [EC:7.4.2.14]
122111482  Tap2; antigen peptide transporter 2 [KO:K05654] [EC:7.4.2.14]
122111513  [KO:K03283]
122112157  [KO:K01365] [EC:3.4.22.15]
122112884  [KO:K08063]
122113383  Psme1; proteasome activator complex subunit 1 [KO:K06696]
122113384  Psme2; proteasome activator complex subunit 2 isoform X1 [KO:K06697]
122113644  [KO:K01365] [EC:3.4.22.15]
122113659  [KO:K01365] [EC:3.4.22.15]
122113774  [KO:K01365] [EC:3.4.22.15]
122113775  [KO:K01365] [EC:3.4.22.15]
122113776  [KO:K01365] [EC:3.4.22.15]
122113777  [KO:K01365] [EC:3.4.22.15]
122113778  [KO:K01365] [EC:3.4.22.15]
122113780  [KO:K01365] [EC:3.4.22.15]
122114339  Pdia3; protein disulfide-isomerase A3 [KO:K08056] [EC:5.3.4.1]
122114656  B2m; beta-2-microglobulin [KO:K08055]
122114887  [KO:K01365] [EC:3.4.22.15]
122115369  Hspa4; heat shock 70 kDa protein 4 [KO:K09489]
122115476  Canx; calnexin isoform X1 [KO:K08054]
122116885  Cd8b; T-cell surface glycoprotein CD8 beta chain [KO:K06459]
122116910  Cd8a; T-cell surface glycoprotein CD8 alpha chain isoform X1 [KO:K06458]
122118063  Cd74; HLA class II histocompatibility antigen gamma chain isoform X1 [KO:K06505]
122118712  Lgmn; legumain isoform X1 [KO:K01369] [EC:3.4.22.34]
122119216  Nfyb; nuclear transcription factor Y subunit beta [KO:K08065]
122122628  Hsp90aa1; heat shock protein HSP 90-alpha [KO:K04079]
122123888  Ciita; MHC class II transactivator isoform X1 [KO:K08060] [EC:2.7.11.1]
122124303  Ifng; interferon gamma [KO:K04687]
122125257  Ctsb; cathepsin B isoform X1 [KO:K01363] [EC:3.4.22.1]
122125452  [KO:K10784]
122125471  [KO:K10784]
Reference
PMID:15771591
  Authors
Trombetta ES, Mellman I.
  Title
Cell biology of antigen processing in vitro and in vivo.
  Journal
Annu Rev Immunol 23:975-1028 (2005)
DOI:10.1146/annurev.immunol.22.012703.104538
Reference
PMID:15814328
  Authors
Inaba K, Inaba M.
  Title
Antigen recognition and presentation by dendritic cells.
  Journal
Int J Hematol 81:181-7 (2005)
DOI:10.1532/IJH97.04200
Reference
PMID:11905820
  Authors
Heath WR, Carbone FR.
  Title
Cross-presentation in viral immunity and self-tolerance.
  Journal
Nat Rev Immunol 1:126-34 (2001)
DOI:10.1038/35100512
Reference
PMID:15304636
  Authors
Abele R, Tampe R.
  Title
The ABCs of immunology: structure and function of TAP, the transporter associated with antigen processing.
  Journal
Physiology (Bethesda) 19:216-24 (2004)
DOI:10.1152/physiol.00002.2004
Reference
PMID:16200082
  Authors
Reith W, LeibundGut-Landmann S, Waldburger JM.
  Title
Regulation of MHC class II gene expression by the class II transactivator.
  Journal
Nat Rev Immunol 5:793-806 (2005)
DOI:10.1038/nri1708
Reference
PMID:12776207
  Authors
Honey K, Rudensky AY.
  Title
Lysosomal cysteine proteases regulate antigen presentation.
  Journal
Nat Rev Immunol 3:472-82 (2003)
DOI:10.1038/nri1110
Reference
PMID:12974477
  Authors
Sercarz EE, Maverakis E.
  Title
Mhc-guided processing: binding of large antigen fragments.
  Journal
Nat Rev Immunol 3:621-9 (2003)
DOI:10.1038/nri1149
Reference
PMID:15224093
  Authors
Ackerman AL, Cresswell P.
  Title
Cellular mechanisms governing cross-presentation of exogenous antigens.
  Journal
Nat Immunol 5:678-84 (2004)
DOI:10.1038/ni1082
Reference
PMID:16181333
  Authors
Cresswell P, Ackerman AL, Giodini A, Peaper DR, Wearsch PA.
  Title
Mechanisms of MHC class I-restricted antigen processing and cross-presentation.
  Journal
Immunol Rev 207:145-57 (2005)
DOI:10.1111/j.0105-2896.2005.00316.x
Reference
PMID:15653312
  Authors
Zika E, Ting JP.
  Title
Epigenetic control of MHC-II: interplay between CIITA and histone-modifying enzymes.
  Journal
Curr Opin Immunol 17:58-64 (2005)
DOI:10.1016/j.coi.2004.11.008
Reference
PMID:11244040
  Authors
Reith W, Mach B.
  Title
The bare lymphocyte syndrome and the regulation of MHC expression.
  Journal
Annu Rev Immunol 19:331-73 (2001)
DOI:10.1146/annurev.immunol.19.1.331
Reference
PMID:15745856
  Authors
Lizee G, Basha G, Jefferies WA.
  Title
Tails of wonder: endocytic-sorting motifs key for exogenous antigen presentation.
  Journal
Trends Immunol 26:141-9 (2005)
DOI:10.1016/j.it.2005.01.005
Reference
PMID:15224094
  Authors
Watts C.
  Title
The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules.
  Journal
Nat Immunol 5:685-92 (2004)
DOI:10.1038/ni1088
Reference
PMID:15653315
  Authors
Kaufmann SH, Schaible UE.
  Title
Antigen presentation and recognition in bacterial infections.
  Journal
Curr Opin Immunol 17:79-87 (2005)
DOI:10.1016/j.coi.2004.12.004
Reference
PMID:20010787
  Authors
Groettrup M, Kirk CJ, Basler M
  Title
Proteasomes in immune cells: more than peptide producers?
  Journal
Nat Rev Immunol 10:73-8 (2010)
DOI:10.1038/nri2687
Related
pathway
dsp03050  Proteasome
dsp04650  Natural killer cell mediated cytotoxicity
dsp04660  T cell receptor signaling pathway
KO pathway
ko04612   

DBGET integrated database retrieval system