KEGG   PATHWAY: hahe00230
Entry
hahe00230                   Pathway                                
Name
Purine metabolism - Hahella sp. KA22
Class
Metabolism; Nucleotide metabolism
Pathway map
hahe00230  Purine metabolism
hahe00230

Module
hahe_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:hahe00230]
hahe_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:hahe00230]
hahe_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:hahe00230]
hahe_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:hahe00230]
hahe_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:hahe00230]
hahe_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:hahe00230]
hahe_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:hahe00230]
Other DBs
GO: 0006163 0042278
Organism
Hahella sp. KA22 [GN:hahe]
Gene
ENC22_25810  ADP-ribose diphosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
ENC22_15865  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
ENC22_04255  phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
ENC22_22970  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
ENC22_03770  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
ENC22_22080  ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
ENC22_11105  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
ENC22_25895  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
ENC22_21265  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
ENC22_20405  formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
ENC22_20435  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
ENC22_21260  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
ENC22_09770  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
ENC22_09775  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
ENC22_08365  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
ENC22_10585  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
ENC22_25890  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
ENC22_28655  5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
ENC22_01695  bifunctional metallophosphatase/5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
ENC22_10525  bifunctional UDP-sugar hydrolase/5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
ENC22_21400  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
ENC22_02370  GMP/IMP nucleotidase [KO:K20881] [EC:3.1.3.-]
ENC22_15860  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
ENC22_07655  pyrimidine/purine nucleoside phosphorylase [KO:K09913] [EC:2.4.2.1 2.4.2.2]
ENC22_25445  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
ENC22_03150  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
ENC22_08180  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
ENC22_19795  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
ENC22_01860  non-canonical purine NTP phosphatase [KO:K01529] [EC:3.6.1.73]
ENC22_27895  XTP/dITP diphosphatase [KO:K01519] [EC:3.6.1.66]
ENC22_25210  xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
ENC22_25160  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
ENC22_25165  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
ENC22_08185  glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
ENC22_20125  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
ENC22_25200  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
ENC22_27640  guanylate kinase [KO:K00942] [EC:2.7.4.8]
ENC22_08415  adenosylcobalamin-dependent ribonucleoside-diphosphate reductase [KO:K00525] [EC:1.17.4.1]
ENC22_30115  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
ENC22_30110  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
ENC22_13885  5'-deoxynucleotidase [KO:K08722] [EC:3.1.3.89]
ENC22_27630  RelA/SpoT family protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
ENC22_01325  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
ENC22_21710  GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
ENC22_19920  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
ENC22_10570  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
ENC22_09580  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
ENC22_01385  class I adenylate cyclase [KO:K05851] [EC:4.6.1.1]
ENC22_06245  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
ENC22_02630  LOG family protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
ENC22_23030  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
ENC22_21685  adenylate kinase [KO:K00939] [EC:2.7.4.3]
ENC22_21705  nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
ENC22_25800  3',5'-cyclic-AMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
ENC22_29145  phosphorylase [KO:K00988] [EC:2.7.7.5 2.7.7.53]
ENC22_26290  symmetrical bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
ENC22_17945  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
ENC22_26600  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
ENC22_06390  cysN; sulfate adenylyltransferase subunit CysN [KO:K00956] [EC:2.7.7.4]
ENC22_06395  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
ENC22_25190  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
ENC22_25185  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
ENC22_25175  allB; allantoinase AllB [KO:K01466] [EC:3.5.2.5]
ENC22_25180  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
ENC22_24890  (S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
ENC22_25195  ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
ENC22_20080  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
ENC22_20070  urease subunit beta [KO:K01429] [EC:3.5.1.5]
ENC22_20065  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
ENC22_05765  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
hahe00030  Pentose phosphate pathway
hahe00220  Arginine biosynthesis
hahe00250  Alanine, aspartate and glutamate metabolism
hahe00260  Glycine, serine and threonine metabolism
hahe00340  Histidine metabolism
hahe00630  Glyoxylate and dicarboxylate metabolism
hahe00730  Thiamine metabolism
hahe00740  Riboflavin metabolism
hahe00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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