KEGG   Homo sapiens (human): 2099
Entry
2099              CDS       T01001                                 
Symbol
ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1
Name
(RefSeq) estrogen receptor 1
  KO
K08550  estrogen receptor alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa01522  Endocrine resistance
hsa04915  Estrogen signaling pathway
hsa04917  Prolactin signaling pathway
hsa04919  Thyroid hormone signaling pathway
hsa04961  Endocrine and other factor-regulated calcium reabsorption
hsa05200  Pathways in cancer
hsa05205  Proteoglycans in cancer
hsa05207  Chemical carcinogenesis - receptor activation
hsa05224  Breast cancer
Network
nt06210  ERK signaling (cancer)
nt06214  PI3K signaling (cancer)
nt06227  Nuclear receptor signaling (cancer)
nt06270  Breast cancer
nt06323  KISS1-GnRH-LH/FSH-E2 signaling
  Element
N00286  Nuclear-initiated estrogen signaling pathway
N00287  ESR1-positive to nuclear-initiated estrogen signaling pathway
N01350  NNK/NNN to PI3K signaling pathway
N01351  E2-ER-RAS-ERK signaling pathway
N01352  BPA to RAS-ERK signaling pathway
N01353  E2 to RAS-ERK signaling pathway
N01364  E2 to nuclear-initiated estrogen signaling pathway
Disease
H00031  Breast cancer
H01730  Myocardial infarction
H02061  Estrogen resistance syndrome
Drug target
Acolbifene hydrochloride: D02758
Afimoxifene: D06551
Alfatradiol: D07121
Amcenestrant: D12145
Arzoxifene hydrochloride: D02993
Bazedoxifene: D03062<JP>
Brilanestrant: D11264
Camizestrant: D12049
Chlorotrianisene: D00269
Clometherone: D03551
Clomifene (DG00474): D00962<JP/US> D07726
Danazol: D00289<JP/US>
Delmadinone (DG02935): D07783
Desogestrel: D02367
Dienestrol: D00898
Diethylstilbestrol (DG00466): D00577 D00946 D07826
Droloxifene (DG01265): D03911 D03912
Elacestrant (DG03078): D11671 D11672<US>
Enclomiphene (DG01992): D08910 D10876
Epitiostanol: D01265
Equilin: D04041
Estetrol (DG03027): D11513 D11514
Estradiol (DG00462): D00105<JP/US> D01413<JP/US> D01617 D01953 D04061<US> D04063<US> D04064 D04065 D07918<US> D07919
Estriol (DG00463): D00185<JP> D01986 D01989 D07920 D07921
Estrogens, esterified: D04071<US>
Estrone (DG00464): D00067 D00312 D00948
Ethinylestradiol (DG00461): D00554<JP> D07928
Etonogestrel: D04104<US>
Etynodiol (DG00470): D01294 D07939
Fispemifene: D10008
Fluoroestradiol (18F): D11829<US>
Fulvestrant: D01161<JP/US>
Giredestrant (DG03318): D11961 D12943
Hexestrol (DG02847): D01641 D02018
Idoxifene: D04496
Lasofoxifene: D04672
Levormeloxifene fumarate: D09834
Mepitiostane: D01602
Mestranol: D00575
Miproxifene phosphate: D01853
Nafoxidine hydrochloride: D05106
Nitromifene citrate: D05192
Ormeloxifene: D08301
Ospemifene: D08958<US>
Palazestrant: D12827
Polyestradiol phosphate: D07434
Prasterone (DG00141): D01616 D08409<US>
Promestriene: D07221
Quinestrol: D00576
Raloxifene (DG00476): D02217<JP/US> D08465 D10606<JP>
Tamoxifen (DG00734): D00966<JP/US> D08559
Tibolone: D01639
Toremifene (DG00735): D00967<JP/US> D08620
Trioxifene mesylate: D06245
Vepdegestrant: D12628
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    2099 (ESR1)
   04917 Prolactin signaling pathway
    2099 (ESR1)
   04919 Thyroid hormone signaling pathway
    2099 (ESR1)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    2099 (ESR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    2099 (ESR1)
   05205 Proteoglycans in cancer
    2099 (ESR1)
   05207 Chemical carcinogenesis - receptor activation
    2099 (ESR1)
  09162 Cancer: specific types
   05224 Breast cancer
    2099 (ESR1)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    2099 (ESR1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    2099 (ESR1)
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors [BR:hsa03310]
    2099 (ESR1)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Zinc finger
   Cys4 estrogen receptor-like
    2099 (ESR1)
Nuclear receptors [BR:hsa03310]
 3. Estrogen like
  3A. Estrogen receptor
   2099 (ESR1)
SSDB
Motif
Pfam: Oest_recep zf-C4 Hormone_recep ESR1_C
Other DBs
NCBI-GeneID: 2099
NCBI-ProteinID: NP_000116
OMIM: 133430
HGNC: 3467
Ensembl: ENSG00000091831
Pharos: P03372(Tclin)
UniProt: P03372 G4XH65
Structure
LinkDB
Position
6:151656672..152129619
AA seq 595 aa
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY
EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF
LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK
ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC
RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR
SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW
AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG
MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD
KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL
LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
NT seq 1788 nt   +upstreamnt  +downstreamnt
atgaccatgaccctccacaccaaagcatctgggatggccctactgcatcagatccaaggg
aacgagctggagcccctgaaccgtccgcagctcaagatccccctggagcggcccctgggc
gaggtgtacctggacagcagcaagcccgccgtgtacaactaccccgagggcgccgcctac
gagttcaacgccgcggccgccgccaacgcgcaggtctacggtcagaccggcctcccctac
ggccccgggtctgaggctgcggcgttcggctccaacggcctggggggtttccccccactc
aacagcgtgtctccgagcccgctgatgctactgcacccgccgccgcagctgtcgcctttc
ctgcagccccacggccagcaggtgccctactacctggagaacgagcccagcggctacacg
gtgcgcgaggccggcccgccggcattctacaggccaaattcagataatcgacgccagggt
ggcagagaaagattggccagtaccaatgacaagggaagtatggctatggaatctgccaag
gagactcgctactgtgcagtgtgcaatgactatgcttcaggctaccattatggagtctgg
tcctgtgagggctgcaaggccttcttcaagagaagtattcaaggacataacgactatatg
tgtccagccaccaaccagtgcaccattgataaaaacaggaggaagagctgccaggcctgc
cggctccgtaaatgctacgaagtgggaatgatgaaaggtgggatacgaaaagaccgaaga
ggagggagaatgttgaaacacaagcgccagagagatgatggggagggcaggggtgaagtg
gggtctgctggagacatgagagctgccaacctttggccaagcccgctcatgatcaaacgc
tctaagaagaacagcctggccttgtccctgacggccgaccagatggtcagtgccttgttg
gatgctgagcccccgatactctattccgagtatgatcctaccagacccttcagtgaagct
tcgatgatgggcttactgaccaacctggcagacagggagctggttcacatgatcaactgg
gcgaagagggtgccaggctttgtggatttgaccctccatgatcaggtccaccttctagaa
tgtgcctggctagagatcctgatgattggtctcgtctggcgctccatggagcacccaggg
aagctactgtttgctcctaacttgctcttggacaggaaccagggaaaatgtgtagagggc
atggtggagatcttcgacatgctgctggctacatcatctcggttccgcatgatgaatctg
cagggagaggagtttgtgtgcctcaaatctattattttgcttaattctggagtgtacaca
tttctgtccagcaccctgaagtctctggaagagaaggaccatatccaccgagtcctggac
aagatcacagacactttgatccacctgatggccaaggcaggcctgaccctgcagcagcag
caccagcggctggcccagctcctcctcatcctctcccacatcaggcacatgagtaacaaa
ggcatggagcatctgtacagcatgaagtgcaagaacgtggtgcccctctatgacctgctg
ctggagatgctggacgcccaccgcctacatgcgcccactagccgtggaggggcatccgtg
gaggagacggaccaaagccacttggccactgcgggctctacttcatcgcattccttgcaa
aagtattacatcacgggggaggcagagggtttccctgccacggtctga

KEGG   Homo sapiens (human): 2100
Entry
2100              CDS       T01001                                 
Symbol
ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2, ODG8
Name
(RefSeq) estrogen receptor 2
  KO
K08551  estrogen receptor beta
Organism
hsa  Homo sapiens (human)
Pathway
hsa01522  Endocrine resistance
hsa04915  Estrogen signaling pathway
hsa04917  Prolactin signaling pathway
hsa04929  GnRH secretion
hsa05200  Pathways in cancer
hsa05207  Chemical carcinogenesis - receptor activation
hsa05224  Breast cancer
Network
nt06210  ERK signaling (cancer)
nt06214  PI3K signaling (cancer)
nt06227  Nuclear receptor signaling (cancer)
nt06270  Breast cancer
nt06323  KISS1-GnRH-LH/FSH-E2 signaling
  Element
N00286  Nuclear-initiated estrogen signaling pathway
N01350  NNK/NNN to PI3K signaling pathway
N01351  E2-ER-RAS-ERK signaling pathway
N01352  BPA to RAS-ERK signaling pathway
N01353  E2 to RAS-ERK signaling pathway
N01364  E2 to nuclear-initiated estrogen signaling pathway
Disease
H00599  Ovarian dysgenesis
Drug target
Acolbifene hydrochloride: D02758
Afimoxifene: D06551
Alfatradiol: D07121
Arzoxifene hydrochloride: D02993
Bazedoxifene: D03062<JP>
Brilanestrant: D11264
Chlorotrianisene: D00269
Clometherone: D03551
Clomifene (DG00474): D00962<JP/US> D07726
Delmadinone (DG02935): D07783
Dienestrol: D00898
Diethylstilbestrol (DG00466): D00577 D00946 D07826
Droloxifene (DG01265): D03911 D03912
Enclomiphene (DG01992): D08910 D10876
Epitiostanol: D01265
Equilin: D04041
Erteberel: D09899
Estetrol (DG03027): D11513 D11514
Estradiol (DG00462): D00105<JP/US> D01413<JP/US> D01617 D01953 D04061<US> D04063<US> D04064 D04065 D07918<US> D07919
Estriol (DG00463): D00185<JP> D01986 D01989 D07920 D07921
Estrogens, esterified: D04071<US>
Estrone (DG00464): D00067 D00312 D00948
Fispemifene: D10008
Fluoroestradiol (18F): D11829<US>
Fulvestrant: D01161<JP/US>
Hexestrol (DG02847): D01641 D02018
Idoxifene: D04496
Lasofoxifene: D04672
Levormeloxifene fumarate: D09834
Mepitiostane: D01602
Mestranol: D00575
Miproxifene phosphate: D01853
Nafoxidine hydrochloride: D05106
Nitromifene citrate: D05192
Ormeloxifene: D08301
Prasterone (DG00141): D01616 D08409<US>
Prinaberel: D06631
Promestriene: D07221
Raloxifene (DG00476): D02217<JP/US> D08465 D10606<JP>
Tamoxifen (DG00734): D00966<JP/US> D08559
Toremifene (DG00735): D00967<JP/US> D08620
Trioxifene mesylate: D06245
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04929 GnRH secretion
    2100 (ESR2)
   04915 Estrogen signaling pathway
    2100 (ESR2)
   04917 Prolactin signaling pathway
    2100 (ESR2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    2100 (ESR2)
   05207 Chemical carcinogenesis - receptor activation
    2100 (ESR2)
  09162 Cancer: specific types
   05224 Breast cancer
    2100 (ESR2)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    2100 (ESR2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    2100 (ESR2)
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors [BR:hsa03310]
    2100 (ESR2)
Transcription factors [BR:hsa03000]
 Eukaryotic type
  Zinc finger
   Cys4 estrogen receptor-like
    2100 (ESR2)
Nuclear receptors [BR:hsa03310]
 3. Estrogen like
  3A. Estrogen receptor
   2100 (ESR2)
SSDB
Motif
Pfam: ERbeta_N zf-C4 Hormone_recep
Other DBs
NCBI-GeneID: 2100
NCBI-ProteinID: NP_001428
OMIM: 601663
HGNC: 3468
Ensembl: ENSG00000140009
Pharos: Q92731(Tclin)
UniProt: Q92731 Q7LCB3
Structure
LinkDB
Position
14:complement(64226707..64338613)
AA seq 530 aa
MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS
NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN
RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH
NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH
CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK
LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL
VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA
DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK
CKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ
NT seq 1593 nt   +upstreamnt  +downstreamnt
atggatataaaaaactcaccatctagccttaattctccttcctcctacaactgcagtcaa
tccatcttacccctggagcacggctccatatacataccttcctcctatgtagacagccac
catgaatatccagccatgacattctatagccctgctgtgatgaattacagcattcccagc
aatgtcactaacttggaaggtgggcctggtcggcagaccacaagcccaaatgtgttgtgg
ccaacacctgggcacctttctcctttagtggtccatcgccagttatcacatctgtatgcg
gaacctcaaaagagtccctggtgtgaagcaagatcgctagaacacaccttacctgtaaac
agagagacactgaaaaggaaggttagtgggaaccgttgcgccagccctgttactggtcca
ggttcaaagagggatgctcacttctgcgctgtctgcagcgattacgcatcgggatatcac
tatggagtctggtcgtgtgaaggatgtaaggccttttttaaaagaagcattcaaggacat
aatgattatatttgtccagctacaaatcagtgtacaatcgataaaaaccggcgcaagagc
tgccaggcctgccgacttcggaagtgttacgaagtgggaatggtgaagtgtggctcccgg
agagagagatgtgggtaccgccttgtgcggagacagagaagtgccgacgagcagctgcac
tgtgccggcaaggccaagagaagtggcggccacgcgccccgagtgcgggagctgctgctg
gacgccctgagccccgagcagctagtgctcaccctcctggaggctgagccgccccatgtg
ctgatcagccgccccagtgcgcccttcaccgaggcctccatgatgatgtccctgaccaag
ttggccgacaaggagttggtacacatgatcagctgggccaagaagattcccggctttgtg
gagctcagcctgttcgaccaagtgcggctcttggagagctgttggatggaggtgttaatg
atggggctgatgtggcgctcaattgaccaccccggcaagctcatctttgctccagatctt
gttctggacagggatgaggggaaatgcgtagaaggaattctggaaatctttgacatgctc
ctggcaactacttcaaggtttcgagagttaaaactccaacacaaagaatatctctgtgtc
aaggccatgatcctgctcaattccagtatgtaccctctggtcacagcgacccaggatgct
gacagcagccggaagctggctcacttgctgaacgccgtgaccgatgctttggtttgggtg
attgccaagagcggcatctcctcccagcagcaatccatgcgcctggctaacctcctgatg
ctcctgtcccacgtcaggcatgcgagtaacaagggcatggaacatctgctcaacatgaag
tgcaaaaatgtggtcccagtgtatgacctgctgctggagatgctgaatgcccacgtgctt
cgcgggtgcaagtcctccatcacggggtccgagtgcagcccggcagaggacagtaaaagc
aaagagggctcccagaacccacagtctcagtga

KEGG   Homo sapiens (human): 8648
Entry
8648              CDS       T01001                                 
Symbol
NCOA1, F-SRC-1, KAT13A, RIP160, SRC1, bHLHe42, bHLHe74
Name
(RefSeq) nuclear receptor coactivator 1
  KO
K09101  nuclear receptor coactivator 1 [EC:2.3.1.48]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04915  Estrogen signaling pathway
hsa04919  Thyroid hormone signaling pathway
hsa05200  Pathways in cancer
hsa05224  Breast cancer
Network
nt06227  Nuclear receptor signaling (cancer)
nt06270  Breast cancer
nt06323  KISS1-GnRH-LH/FSH-E2 signaling
  Element
N00286  Nuclear-initiated estrogen signaling pathway
N00287  ESR1-positive to nuclear-initiated estrogen signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    8648 (NCOA1)
   04919 Thyroid hormone signaling pathway
    8648 (NCOA1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    8648 (NCOA1)
  09162 Cancer: specific types
   05224 Breast cancer
    8648 (NCOA1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    8648 (NCOA1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.48  histone acetyltransferase
     8648 (NCOA1)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   HATs (histone acetyltransferases)
    8648 (NCOA1)
SSDB
Motif
Pfam: PAS_11 DUF1518 SRC-1 NCOA_u2 Nuc_rec_co-act PAS PAS_3 PAS_9 DUF4927 HLH PAS_4 PAS_12
Other DBs
NCBI-GeneID: 8648
NCBI-ProteinID: NP_003734
OMIM: 602691
HGNC: 7668
Ensembl: ENSG00000084676
Pharos: Q15788(Tchem)
UniProt: Q15788
Structure
LinkDB
Position
2:24491254..24770702
AA seq 1441 aa
MSGLGDSSSDPANPDSHKRKGSPCDTLASSTEKRRREQENKYLEELAELLSANISDIDSL
SVKPDKCKILKKTVDQIQLMKRMEQEKSTTDDDVQKSDISSSSQGVIEKESLGPLLLEAL
DGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSLVNG
VPWPQEATRRNSHTFNCRMLIHPPDEPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQ
SCLICIARRLPRPPAITGVESFMTKQDTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFF
QPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLCYPQSPDMQPFIMG
IHIIDREHSGLSPQDDTNSGMSIPRVNPSVNPSISPAHGVARSSTLPPSNSNMVSTRINR
QQSSDLHSSSHSNSSNSQGSFGCSPGSQIVANVALNQGQASSQSSNPSLNLNNSPMEGTG
ISLAQFMSPRRQVTSGLATRPRMPNNSFPPNISTLSSPVGMTSSACNNNNRSYSNIPVTS
LQGMNEGPNNSVGFSASSPVLRQMSSQNSPSRLNIQPAKAESKDNKEIASILNEMIQSDN
SSSDGKPLDSGLLHNNDRLSDGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKDVLSC
TGTSNSASANSSGGSCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPDKKDSASTSVS
VTGQVQGNSSIKLELDASKKKESKDHQLLRYLLDKDEKDLRSTPNLSLDDVKVKVEKKEQ
MDPCNTNPTPMTKPTPEEIKLEAQSQFTADLDQFDQLLPTLEKAAQLPGLCETDRMDGAV
TSVTIKSEILPASLQSATARPTSRLNRLPELELEAIDNQFGQPGTGDQIPWTNNTVTAIN
QSKSEDQCISSQLDELLCPPTTVEGRNDEKALLEQLVSFLSGKDETELAELDRALGIDKL
VQGGGLDVLSERFPPQQATPPLIMEERPNLYSQPYSSPSPTANLPSPFQGMVRQKPSLGT
MPVQVTPPRGAFSPGMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLIHQNRQAILNQF
AATAPVGINMRSGMQQQITPQPPLNAQMLAQRQRELYSQQHRQRQLIQQQRAMLMRQQSF
GNNLPPSSGLPVQMGNPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAANPEASLAN
RNSMVSRGMTGNIGGQFGTGINPQMQQNVFQYPGAGMVPQGEANFAPSLSPGSSMVPMPI
PPPQSSLLQQTPPASGYQSPDMKAWQQGAIGNNNVFSQAVQNQPTPAQPGVYNNMSITVS
MAGGNTNVQNMNPMMAQMQMSSLQMPGMNTVCPEQINDPALRHTGLYCNQLSSTDLLKTE
ADGTQQVQQVQVFADVQCTVNLVGGDPYLNQPGPLGTQKPTSGPQTPQAQQKSLLQQLLT
E
NT seq 4326 nt   +upstreamnt  +downstreamnt
atgagtggcctcggggacagttcatccgaccctgctaacccagactcacataagaggaaa
ggatcgccatgtgacacactggcatcaagcacggaaaagaggcgcagggagcaagaaaat
aaatatttagaagaactagctgagttactgtctgccaacattagtgacattgacagcttg
agtgtaaaaccagacaaatgcaagattttgaagaaaacagtcgatcagatacagctaatg
aagagaatggaacaagagaaatcaacaactgatgacgatgtacagaaatcagacatctca
tcaagtagtcaaggagtgatagaaaaggaatccttgggacctcttcttttggaggctttg
gatggatttttctttgttgtgaactgtgaagggagaattgtatttgtgtcagagaatgta
accagctacttaggttacaatcaggaggaattaatgaatacgagcgtctacagcatactg
cacgtgggggatcatgcagaatttgtgaagaatctgctaccaaaatcactagtaaatgga
gttccttggcctcaagaggcaacacgacgaaatagccatacctttaactgcaggatgcta
attcaccctccagatgagccagggaccgagaaccaagaagcttgccagcgttatgaagta
atgcagtgtttcactgtgtcacagccaaaatcaattcaagaggatggagaagatttccag
tcatgtctgatttgtattgcacggcgattacctcggcctccagctattacgggtgtagaa
tcctttatgaccaagcaagatactacaggtaaaatcatctctattgatactagttccctg
agagctgctggcagaactggttgggaagatttagtgaggaagtgcatttatgcttttttc
caacctcagggcagagaaccatcttatgccagacagctgttccaagaagtgatgactcgt
ggcactgcctccagcccctcctatagattcatattgaatgatgggacaatgcttagcgcc
cacaccaagtgtaaactttgctaccctcaaagtccagacatgcaacctttcatcatggga
attcatatcatcgacagggagcacagtgggctttctcctcaagatgacactaattctgga
atgtcaattccccgagtaaatccctcggtcaatcctagtatctctccagctcatggtgtg
gctcgttcatccacattgccaccatccaacagcaacatggtatccaccagaataaaccgc
cagcagagctcagaccttcatagcagcagtcatagtaattctagcaacagccaaggaagt
ttcggatgctcacccggaagtcagattgtagccaatgttgccttaaaccaaggacaggcc
agttcacagagcagtaatccctctttaaacctcaataattctcctatggaaggtacagga
atatccctagcacagttcatgtctccaaggagacaggttacttctggattggcaacaagg
cccaggatgccaaacaattcctttcctcctaatatttcgacattaagctctcccgttggc
atgacaagtagtgcctgtaataataataaccgatcttattcaaacatcccagtaacatct
ttacagggtatgaatgaaggacccaataactccgttggcttctctgccagttctccagtc
ctcaggcagatgagctcacagaattcacctagcagattaaatatacaaccagcaaaagct
gagtccaaagataacaaagagattgcctcaattttaaatgaaatgattcaatctgacaac
agctctagtgatggcaaacctctggattcagggcttctgcataacaatgacagactttca
gatggagacagtaaatactctcaaaccagtcacaaactagtgcagcttttgacaacaact
gccgaacagcagttacggcatgctgatatagacacaagctgcaaagatgtcctgtcttgc
acaggcacttccaactctgcctctgctaactcttcaggaggttcttgtccctcttctcat
agctcattgacagaacggcataaaattctacaccggctcttacaggagggtagcccctca
gatatcaccactttgtctgtcgagcctgataaaaaggacagtgcatctacttctgtgtca
gtgactggacaggtacaaggaaactccagtataaaactagaactggatgcttcaaagaaa
aaagaatcaaaagaccatcagctcctacgctatcttttagataaagatgagaaagattta
agatcaactccaaacctgagcctggatgatgtaaaggtgaaagtggaaaagaaagaacag
atggatccatgtaatacaaacccaaccccaatgaccaaacccactcctgaggaaataaaa
ctggaggcccagagccagtttacagctgaccttgaccagtttgatcagttactgcccacg
ctggagaaggcagcacagttgccaggcttatgtgagacagacaggatggatggtgcggtc
accagtgtaaccatcaaatcggagatcctgccagcttcacttcagtccgccactgccaga
cccacttccaggctaaatagattacctgagctggaattggaagcaattgataaccaattt
ggacaaccaggaacaggcgatcagattccatggacaaataatacagtgacagctataaat
cagagtaaatcagaagaccagtgtattagctcacaattagatgagcttctctgtccaccc
acaacagtagaagggagaaatgatgagaaggctcttcttgaacagctggtatccttcctt
agtggcaaagatgaaactgagctagctgaactagacagagctctgggaattgacaaactt
gttcaggggggtggattagatgtattatcagagagatttccaccacaacaagcaacgcca
cctttgatcatggaagaaagacccaacctttattcccagccttactcttctccttctcct
actgccaatctccctagccctttccaaggcatggtcaggcaaaaaccttcactggggacg
atgcctgttcaagtaacacctccccgaggtgctttttcacctggcatgggcatgcagccc
aggcaaactctaaacagacctccggctgcacctaaccagcttcgacttcaactacagcag
cgattacagggacaacagcagttgatacaccaaaatcggcaagctatcttaaaccagttt
gcagcaactgctcctgttggcatcaatatgagatcaggcatgcaacagcaaattacacct
cagccacccctgaatgctcaaatgttggcacaacgtcagcgggaactgtacagtcaacag
caccgacagaggcagctaatacagcagcaaagagccatgcttatgaggcagcaaagcttt
gggaacaacctccctccctcatctggactaccagttcaaatggggaacccccgtcttcct
cagggtgctccacagcaattcccctatccaccaaactatggtacaaatccaggaacccca
cctgcttctaccagcccgttttcacaactagcagcaaatcctgaagcatccttggccaac
cgcaacagcatggtgagcagaggcatgacaggaaacataggaggacagtttggcactgga
atcaatcctcagatgcagcagaatgtcttccagtatccaggagcaggaatggttccccaa
ggtgaggccaactttgctccatctctaagccctgggagctccatggtgccgatgccaatc
cctcctcctcagagttctcttctccagcaaactccacctgcctccgggtatcagtcacca
gacatgaaggcctggcagcaaggagcgataggaaacaacaatgtgttcagtcaagctgtc
cagaaccagcccacgcctgcacagccaggagtatacaacaacatgagcatcaccgtttcc
atggcaggtggaaatacgaatgttcagaacatgaacccaatgatggcccagatgcagatg
agctctttgcagatgccaggaatgaacactgtgtgccctgagcagataaatgatcccgca
ctgagacacacaggcctctactgcaaccagctctcatccactgaccttctcaaaacagaa
gcagatggaacccagcaggtgcaacaggttcaggtgtttgctgacgtccagtgtacagtg
aatctggtaggcggggacccttacctgaaccagcctggtccactgggaactcaaaagccc
acgtcaggaccacagaccccccaggcccagcagaagagcctccttcagcagctactgact
gaataa

KEGG   Homo sapiens (human): 10499
Entry
10499             CDS       T01001                                 
Symbol
NCOA2, GRIP1, KAT13C, NCoA-2, SRC2, TIF2, bHLHe75
Name
(RefSeq) nuclear receptor coactivator 2
  KO
K11255  nuclear receptor coactivator 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04915  Estrogen signaling pathway
hsa04919  Thyroid hormone signaling pathway
Network
nt06227  Nuclear receptor signaling (cancer)
nt06270  Breast cancer
nt06323  KISS1-GnRH-LH/FSH-E2 signaling
  Element
N00286  Nuclear-initiated estrogen signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    10499 (NCOA2)
   04919 Thyroid hormone signaling pathway
    10499 (NCOA2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    10499 (NCOA2)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   HATs (histone acetyltransferases)
    10499 (NCOA2)
SSDB
Motif
Pfam: NCOA_u2 PAS_11 DUF4927 DUF1518 Nuc_rec_co-act SRC-1 PAS_3 PAS PAS_9 HLH PAS_4
Other DBs
NCBI-GeneID: 10499
NCBI-ProteinID: NP_001308632
OMIM: 601993
HGNC: 7669
Ensembl: ENSG00000140396
Pharos: Q15596(Tbio)
UniProt: Q15596
Structure
LinkDB
Position
8:complement(70109782..70456446)
AA seq 1464 aa
MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDI
DNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMML
EALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSI
VNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKE
EGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLV
RRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQT
TNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLS
SNINFPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPG
QPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQAL
SEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQA
ESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASS
LSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESS
STAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTK
LIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAII
NDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAG
PFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSA
VRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGG
PQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALL
DQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQ
AQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQ
QNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQ
RTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGISQQPDPGFTGATT
PQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQSPPHFGQQAN
TSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQVNDPALRGG
NLFPNQLPGMDMIKQEGDTTRKYC
NT seq 4395 nt   +upstreamnt  +downstreamnt
atgagtgggatgggagaaaatacctctgacccctccagggcagagacaagaaagcgcaag
gaatgtcctgaccaacttggacccagccccaaaaggaacactgaaaaacgtaatcgtgaa
caggaaaataaatatatagaagaacttgcagagttgatttttgcaaattttaatgatata
gacaactttaacttcaaacctgacaaatgtgcaatcttaaaagaaactgtgaagcaaatt
cgtcagatcaaagaacaagagaaagcagcagctgccaacatagatgaagtgcagaagtca
gatgtatcctctacagggcagggtgtcatcgacaaggatgcgctggggcctatgatgctt
gaggcccttgatgggttcttctttgtagtgaacctggaaggcaacgttgtgtttgtgtca
gagaatgtgacacagtatctaaggtataaccaagaagagctgatgaacaaaagtgtatat
agcatcttgcatgttggggaccacacggaatttgtcaaaaacctgctgccaaagtctata
gtaaatgggggatcttggtctggcgaacctccgaggcggaacagccataccttcaattgt
cggatgctggtaaaacctttacctgattcagaagaggagggtcatgataaccaggaagct
catcagaaatatgaaactatgcagtgcttcgctgtctctcaaccaaagtccatcaaagaa
gaaggagaagatttgcagtcctgcttgatttgcgtggcaagaagagttcccatgaaggaa
agaccagttcttccctcatcagaaagttttactactcgccaggatctccaaggcaagatc
acgtctctggataccagcaccatgagagcagccatgaaaccaggctgggaggacctggta
agaaggtgtattcagaagttccatgcgcagcatgaaggagaatctgtgtcctatgctaag
aggcatcatcatgaagtactgagacaaggattggcattcagtcaaatctatcgtttttcc
ttgtctgatggcactcttgttgctgcacaaacgaagagcaaactcatccgttctcagact
actaatgaacctcaacttgtaatatctttacatatgcttcacagagagcagaatgtgtgt
gtgatgaatccggatctgactggacaaacgatggggaagccactgaatccaattagctct
aacagccctgcccatcaggccctgtgcagtgggaacccaggtcaggacatgaccctcagt
agcaatataaattttcccataaatggcccaaaggaacaaatgggcatgcccatgggcagg
tttggtggttctgggggaatgaaccatgtgtcaggcatgcaagcaaccactcctcagggt
agtaactatgcactcaaaatgaacagcccctcacaaagcagccctggcatgaatccagga
cagcccacctccatgctttcaccaaggcatcgcatgagccctggagtggctggcagccct
cgaatcccacccagtcagttttcccctgcaggaagcttgcattcccctgtgggagtttgc
agcagcacaggaaatagccatagttataccaacagctccctcaatgcacttcaggccctc
agcgaggggcacggggtctcattagggtcatcgttggcttcaccagacctaaaaatgggc
aatttgcaaaactccccagttaatatgaatcctcccccactcagcaagatgggaagcttg
gactcaaaagactgttttggactatatggggagccctctgaaggtacaactggacaagca
gagagcagctgccatcctggagagcaaaaggaaacaaatgaccccaacctgcccccggcc
gtgagcagtgagagagctgacgggcagagcagactgcatgacagcaaagggcagaccaaa
ctcctgcagctgctgaccaccaaatctgatcagatggagccctcgcccttagccagctct
ttgtcggatacaaacaaagactccacaggtagcttgcctggttctgggtctacacatgga
acctcgctcaaggagaagcataaaattttgcacagactcttgcaggacagcagttcccct
gtggacttggccaagttaacagcagaagccacaggcaaagacctgagccaggagtccagc
agcacagctcctggatcagaagtgactattaaacaagagccggtgagccccaagaagaaa
gagaatgcactacttcgctatttgctagataaagatgatactaaagatattggtttacca
gaaataacccccaaacttgagagactggacagtaagacagatcctgccagtaacacaaaa
ttaatagcaatgaaaactgagaaggaggagatgagctttgagcctggtgaccagcctggc
agtgagctggacaacttggaggagattttggatgatttgcagaatagtcaattaccacag
cttttcccagacacgaggccaggcgcccctgctggatcagttgacaagcaagccatcatc
aatgacctcatgcaactcacagctgaaaacagccctgtcacacctgttggagcccagaaa
acagcactgcgaatttcacagagcacttttaataacccacgaccagggcaactgggcagg
ttattgccaaaccagaatttaccacttgacatcacattgcaaagcccaactggtgctgga
cctttcccaccaatcagaaacagtagtccctactcagtgatacctcagccaggaatgatg
ggtaatcaagggatgataggaaaccaaggaaatttagggaacagtagcacaggaatgatt
ggtaacagtgcttctcggcctactatgccatctggagaatgggcaccgcagagttcggct
gtgagagtcacctgtgctgctaccaccagtgccatgaaccggccagtccaaggaggtatg
attcggaacccagcagccagcatccccatgaggcccagcagccagcctggccaaagacag
acgcttcagtctcaggtcatgaatatagggccatctgaattagagatgaacatgggggga
cctcagtatagccaacaacaagctcctccaaatcagactgccccatggcctgaaagcatc
ctgcctatagaccaggcgtcttttgccagccaaaacaggcagccatttggcagttctcca
gatgacttgctatgtccacatcctgcagctgagtctccgagtgatgagggagctctcctg
gaccagctgtatctggccttgcggaattttgatggcctggaggagattgatagagcctta
ggaatacccgaactggtcagccagagccaagcagtagatccagaacagttctcaagtcag
gattccaacatcatgctggagcagaaggcgcccgttttcccacagcagtatgcatctcag
gcacaaatggcccagggtagctattctcccatgcaagatccaaactttcacaccatggga
cagcggcctagttatgccacactccgtatgcagcccagaccgggcctcaggcccacgggc
ctagtgcagaaccagccaaatcaactaagacttcaacttcagcatcgcctccaagcacag
cagaatcgccagccacttatgaatcaaatcagcaatgtttccaatgtgaacttgactctg
aggcctggagtaccaacacaggcacctattaatgcacagatgctggcccagagacagagg
gaaatcctgaaccagcatcttcgacagagacaaatgcatcagcaacagcaagttcagcaa
cgaactttgatgatgagaggacaagggttgaatatgacaccaagcatggtggctcctagt
ggtatgccagcaactatgagcaaccctcggattccccaggcaaatgcacagcagtttcca
tttcctccaaactacggaataagtcagcaacctgatccaggctttactggggctacgact
ccccagagcccacttatgtcaccccgaatggcacatacacagagtcccatgatgcaacag
tctcaggccaacccagcctatcaggccccctccgacataaatggatgggcgcaggggaac
atgggcggaaacagcatgttttcccagcagtccccaccacactttgggcagcaagcaaac
accagcatgtacagtaacaacatgaacatcaatgtgtccatggcgaccaacacaggtggc
atgagcagcatgaaccagatgacaggacagatcagcatgacctcagtgacctccgtgcct
acgtcagggctgtcctccatgggtcccgagcaggttaatgatcctgctctgaggggaggc
aacctgttcccaaaccagctgcctggaatggatatgattaagcaggagggagacacaaca
cggaaatattgctga

KEGG   Homo sapiens (human): 8202
Entry
8202              CDS       T01001                                 
Symbol
NCOA3, ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, RAC3, SRC-3, SRC3, TNRC14, TNRC16, TRAM-1, bHLHe42, pCIP
Name
(RefSeq) nuclear receptor coactivator 3
  KO
K11256  nuclear receptor coactivator 3 [EC:2.3.1.48]
Organism
hsa  Homo sapiens (human)
Pathway
hsa01522  Endocrine resistance
hsa04915  Estrogen signaling pathway
hsa04919  Thyroid hormone signaling pathway
hsa05200  Pathways in cancer
hsa05224  Breast cancer
Network
nt06227  Nuclear receptor signaling (cancer)
nt06270  Breast cancer
nt06323  KISS1-GnRH-LH/FSH-E2 signaling
  Element
N00286  Nuclear-initiated estrogen signaling pathway
N00287  ESR1-positive to nuclear-initiated estrogen signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09152 Endocrine system
   04915 Estrogen signaling pathway
    8202 (NCOA3)
   04919 Thyroid hormone signaling pathway
    8202 (NCOA3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    8202 (NCOA3)
  09162 Cancer: specific types
   05224 Breast cancer
    8202 (NCOA3)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    8202 (NCOA3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    8202 (NCOA3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.48  histone acetyltransferase
     8202 (NCOA3)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   HATs (histone acetyltransferases)
    8202 (NCOA3)
SSDB
Motif
Pfam: NCOA_u2 DUF4927 SRC-1 Nuc_rec_co-act PAS_11 DUF1518 PAS PAS_3 PAS_9 HLH PAS_4 Per3-like_PAS-A TERB2
Other DBs
NCBI-GeneID: 8202
NCBI-ProteinID: NP_858045
OMIM: 601937
HGNC: 7670
Ensembl: ENSG00000124151
Pharos: Q9Y6Q9(Tbio)
UniProt: Q9Y6Q9
Structure
LinkDB
Position
20:47501887..47656872
AA seq 1424 aa
MSGLGENLDPLASDSRKRKLPCDTPGQGLTCSGEKRRREQESKYIEELAELISANLSDID
NFNVKPDKCAILKETVRQIRQIKEQGKTISNDDDVQKADVSSTGQGVIDKDSLGPLLLQA
LDGFLFVVNRDGNIVFVSENVTQYLQYKQEDLVNTSVYNILHEEDRKDFLKNLPKSTVNG
VSWTNETQRQKSHTFNCRMLMKTPHDILEDINASPEMRQRYETMQCFALSQPRAMMEEGE
DLQSCMICVARRITTGERTFPSNPESFITRHDLSGKVVNIDTNSLRSSMRPGFEDIIRRC
IQRFFSLNDGQSWSQKRHYQEAYLNGHAETPVYRFSLADGTIVTAQTKSKLFRNPVTNDR
HGFVSTHFLQREQNGYRPNPNPVGQGIRPPMAGCNSSVGGMSMSPNQGLQMPSSRAYGLA
DPSTTGQMSGARYGGSSNIASLTPGPGMQSPSSYQNNNYGLNMSSPPHGSPGLAPNQQNI
MISPRNRGSPKIASHQFSPVAGVHSPMASSGNTGNHSFSSSSLSALQAISEGVGTSLLST
LSSPGPKLDNSPNMNITQPSKVSNQDSKSPLGFYCDQNPVESSMCQSNSRDHLSDKESKE
SSVEGAENQRGPLESKGHKKLLQLLTCSSDDRGHSSLTNSPLDSSCKESSVSVTSPSGVS
SSTSGGVSSTSNMHGSLLQEKHRILHKLLQNGNSPAEVAKITAEATGKDTSSITSCGDGN
VVKQEQLSPKKKENNALLRYLLDRDDPSDALSKELQPQVEGVDNKMSQCTSSTIPSSSQE
KDPKIKTETSEEGSGDLDNLDAILGDLTSSDFYNNSISSNGSHLGTKQQVFQGTNSLGLK
SSQSVQSIRPPYNRAVSLDSPVSVGSSPPVKNISAFPMLPKQPMLGGNPRMMDSQENYGS
SMGGPNRNVTVTQTPSSGDWGLPNSKAGRMEPMNSNSMGRPGGDYNTSLPRPALGGSIPT
LPLRSNSIPGARPVLQQQQQMLQMRPGEIPMGMGANPYGQAAASNQLGSWPDGMLSMEQV
SHGTQNRPLLRNSLDDLVGPPSNLEGQSDERALLDQLHTLLSNTDATGLEEIDRALGIPE
LVNQGQALEPKQDAFQGQEAAVMMDQKAGLYGQTYPAQGPPMQGGFHLQGQSPSFNSMMN
QMNQQGNFPLQGMHPRANIMRPRTNTPKQLRMQLQQRLQGQQFLNQSRQALELKMENPTA
GGAAVMRPMMQPQVSSQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQ
QQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNYGMGQQ
PDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQAASIYQSSEMKGWPSGNLARNSSFSQQQ
FAHQGNPAVYSMVHMNGSSGHMGQMNMNPMPMSGMPMGPDQKYC
NT seq 4275 nt   +upstreamnt  +downstreamnt
atgagtggattaggagaaaacttggatccactggccagtgattcacgaaaacgcaaattg
ccatgtgatactccaggacaaggtcttacctgcagtggtgaaaaacggagacgggagcag
gaaagtaaatatattgaagaattggctgagctgatatctgccaatcttagtgatattgac
aatttcaatgtcaaaccagataaatgtgcgattttaaaggaaacagtaagacagatacgt
caaataaaagagcaaggaaaaactatttccaatgatgatgatgttcaaaaagccgatgta
tcttctacagggcagggagttattgataaagactccttaggaccgcttttacttcaggca
ttggatggtttcctatttgtggtgaatcgagacggaaacattgtatttgtatcagaaaat
gtcacacaatacctgcaatataagcaagaggacctggttaacacaagtgtttacaatatc
ttacatgaagaagacagaaaggattttcttaagaatttaccaaaatctacagttaatgga
gtttcctggacaaatgagacccaaagacaaaaaagccatacatttaattgccgtatgttg
atgaaaacaccacatgatattctggaagacataaacgccagtcctgaaatgcgccagaga
tatgaaacaatgcagtgctttgccctgtctcagccacgagctatgatggaggaaggggaa
gatttgcaatcttgtatgatctgtgtggcacgccgcattactacaggagaaagaacattt
ccatcaaaccctgagagctttattaccagacatgatctttcaggaaaggttgtcaatata
gatacaaattcactgagatcctccatgaggcctggctttgaagatataatccgaaggtgt
attcagagattttttagtctaaatgatgggcagtcatggtcccagaaacgtcactatcaa
gaagcttatcttaatggccatgcagaaaccccagtatatcgattctcgttggctgatgga
actatagtgactgcacagacaaaaagcaaactcttccgaaatcctgtaacaaatgatcga
catggctttgtctcaacccacttccttcagagagaacagaatggatatagaccaaaccca
aatcctgttggacaagggattagaccacctatggctggatgcaacagttcggtaggcggc
atgagtatgtcgccaaaccaaggcttacagatgccgagcagcagggcctatggcttggca
gaccctagcaccacagggcagatgagtggagctaggtatgggggttccagtaacatagct
tcattgacccctgggccaggcatgcaatcaccatcttcctaccagaacaacaactatggg
ctcaacatgagtagccccccacatgggagtcctggtcttgccccaaaccagcagaatatc
atgatttctcctcgtaatcgtgggagtccaaagatagcctcacatcagttttctcctgtt
gcaggtgtgcactctcccatggcatcttctggcaatactgggaaccacagcttttccagc
agctctctcagtgccctgcaagccatcagtgaaggtgtggggacttcccttttatctact
ctgtcatcaccaggccccaaattggataactctcccaatatgaatattacccaaccaagt
aaagtaagcaatcaggattccaagagtcctctgggcttttattgcgaccaaaatccagtg
gagagttcaatgtgtcagtcaaatagcagagatcacctcagtgacaaagaaagtaaggag
agcagtgttgagggggcagagaatcaaaggggtcctttggaaagcaaaggtcataaaaaa
ttactgcagttacttacctgttcttctgatgaccggggtcattcctccttgaccaactcc
cccctagattcaagttgtaaagaatcttctgttagtgtcaccagcccctctggagtctcc
tcctctacatctggaggagtatcctctacatccaatatgcatgggtcactgttacaagag
aagcaccggattttgcacaagttgctgcagaatgggaattcaccagctgaggtagccaag
attactgcagaagccactgggaaagacaccagcagtataacttcttgtggggacggaaat
gttgtcaagcaggagcagctaagtcctaagaagaaggagaataatgcacttcttagatac
ctgctggacagggatgatcctagtgatgcactctctaaagaactacagccccaagtggaa
ggagtggataataaaatgagtcagtgcaccagctccaccattcctagctcaagtcaagag
aaagaccctaaaattaagacagagacaagtgaagagggatctggagacttggataatcta
gatgctattcttggtgatctgactagttctgacttttacaataattccatatcctcaaat
ggtagtcatctggggactaagcaacaggtgtttcaaggaactaattctctgggtttgaaa
agttcacagtctgtgcagtctattcgtcctccatataaccgagcagtgtctctggatagc
cctgtttctgttggctcaagtcctccagtaaaaaatatcagtgctttccccatgttacca
aagcaacccatgttgggtgggaatccaagaatgatggatagtcaggaaaattatggctca
agtatgggtgggccaaaccgaaatgtgactgtgactcagactccttcctcaggagactgg
ggcttaccaaactcaaaggccggcagaatggaacctatgaattcaaactccatgggaaga
ccaggaggagattataatacttctttacccagacctgcactgggtggctctattcccaca
ttgcctcttcggtctaatagcataccaggtgcgagaccagtattgcaacagcagcagcag
atgcttcaaatgaggcctggtgaaatccccatgggaatgggggctaatccctatggccaa
gcagcagcatctaaccaactgggttcctggcccgatggcatgttgtccatggaacaagtt
tctcatggcactcaaaataggcctcttcttaggaattccctggatgatcttgttgggcca
ccttccaacctggaaggccagagtgacgaaagagcattattggaccagctgcacactctt
ctcagcaacacagatgccacaggcctggaagaaattgacagagctttgggcattcctgaa
cttgtcaatcagggacaggcattagagcccaaacaggatgctttccaaggccaagaagca
gcagtaatgatggatcagaaggcaggattatatggacagacatacccagcacaggggcct
ccaatgcaaggaggctttcatcttcagggacaatcaccatcttttaactctatgatgaat
cagatgaaccagcaaggcaattttcctctccaaggaatgcacccacgagccaacatcatg
agaccccggacaaacacccccaagcaacttagaatgcagcttcagcagaggctgcagggc
cagcagtttttgaatcagagccgacaggcacttgaattgaaaatggaaaaccctactgct
ggtggtgctgcggtgatgaggcctatgatgcagccccaggtgagctcccagcagggtttt
cttaatgctcaaatggtcgcccaacgcagcagagagctgctaagtcatcacttccgacaa
cagagggtggctatgatgatgcagcagcagcagcagcagcaacagcagcagcagcagcag
cagcagcagcaacagcaacagcaacagcaacagcagcaacagcagcaaacccaggccttc
agcccacctcctaatgtgactgcttcccccagcatggatgggcttttggcaggacccaca
atgccacaagctcctccgcaacagtttccatatcaaccaaattatggaatgggacaacaa
ccagatccagcctttggtcgagtgtctagtcctcccaatgcaatgatgtcgtcaagaatg
ggtccctcccagaatcccatgatgcaacacccgcaggctgcatccatctatcagtcctca
gaaatgaagggctggccatcaggaaatttggccaggaacagctccttttcccagcagcag
tttgcccaccaggggaatcctgcagtgtatagtatggtgcacatgaatggcagcagtggt
cacatgggacagatgaacatgaaccccatgcccatgtctggcatgcctatgggtcctgat
cagaaatactgctga

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