Homo sapiens (human): 7187
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Entry
7187 CDS
T01001
Symbol
TRAF3, CAP-1, CAP1, CD40bp, CRAF1, IIAE5, LAP1, RNF118
Name
(RefSeq) TNF receptor associated factor 3
KO
K03174
TNF receptor-associated factor 3
Organism
hsa
Homo sapiens (human)
Pathway
hsa04064
NF-kappa B signaling pathway
hsa04620
Toll-like receptor signaling pathway
hsa04621
NOD-like receptor signaling pathway
hsa04622
RIG-I-like receptor signaling pathway
hsa04657
IL-17 signaling pathway
hsa04668
TNF signaling pathway
hsa04936
Alcoholic liver disease
hsa05160
Hepatitis C
hsa05161
Hepatitis B
hsa05162
Measles
hsa05164
Influenza A
hsa05165
Human papillomavirus infection
hsa05167
Kaposi sarcoma-associated herpesvirus infection
hsa05168
Herpes simplex virus 1 infection
hsa05169
Epstein-Barr virus infection
hsa05171
Coronavirus disease - COVID-19
hsa05200
Pathways in cancer
hsa05203
Viral carcinogenesis
hsa05222
Small cell lung cancer
hsa05417
Lipid and atherosclerosis
Network
nt06160
Human T-cell leukemia virus 1 (HTLV-1)
nt06162
Hepatitis B virus (HBV)
nt06163
Hepatitis C virus (HCV)
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165
Epstein-Barr virus (EBV)
nt06166
Human papillomavirus (HPV)
nt06168
Herpes simplex virus 1 (HSV-1)
nt06169
Measles virus (MV)
nt06170
Influenza A virus (IAV)
nt06171
SARS coronavirus 2 (SARS-CoV-2)
nt06223
TNF signaling (cancer)
nt06263
Hepatocellular carcinoma
nt06516
TNF signaling
nt06517
TLR signaling
nt06519
RLR signaling
Element
N00148
TLR3-IRF7 signaling pathway
N00149
TLR3-IRF3 signaling pathway
N00469
RIG-I-IRF7/3 signaling pathway
N00485
EBV LMP1 to PI3K signaling pathway
N00505
CD40-NFKB signaling pathway
N00553
TLR4-IRF3/7 signaling pathway
N00566
HSV UL36USP to RIG-I-like receptor signaling pathway
N01308
MDA5-IRF7/3 signaling pathway
Disease
H02536
Infection-induced acute encephalopathy
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
7187 (TRAF3)
04668 TNF signaling pathway
7187 (TRAF3)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
7187 (TRAF3)
04621 NOD-like receptor signaling pathway
7187 (TRAF3)
04622 RIG-I-like receptor signaling pathway
7187 (TRAF3)
04657 IL-17 signaling pathway
7187 (TRAF3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
7187 (TRAF3)
05203 Viral carcinogenesis
7187 (TRAF3)
09162 Cancer: specific types
05222 Small cell lung cancer
7187 (TRAF3)
09172 Infectious disease: viral
05161 Hepatitis B
7187 (TRAF3)
05160 Hepatitis C
7187 (TRAF3)
05171 Coronavirus disease - COVID-19
7187 (TRAF3)
05164 Influenza A
7187 (TRAF3)
05162 Measles
7187 (TRAF3)
05168 Herpes simplex virus 1 infection
7187 (TRAF3)
05167 Kaposi sarcoma-associated herpesvirus infection
7187 (TRAF3)
05169 Epstein-Barr virus infection
7187 (TRAF3)
05165 Human papillomavirus infection
7187 (TRAF3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
7187 (TRAF3)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
7187 (TRAF3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TRAF-mep_MATH
TRAF3_RING
zf-TRAF
zf-C3HC4
MPS2
zf-C3HC4_2
ATG16
Spc29
Tropomyosin
Cast
zf-RING_UBOX
Crescentin
KxDL
FliJ
GAS
LMBR1
DUF1664
V_ATPase_I
DUF3450
THOC7
ADIP
BLOC1_2
SPATA24
T3SSipB
Motif
Other DBs
NCBI-GeneID:
7187
NCBI-ProteinID:
NP_003291
OMIM:
601896
HGNC:
12033
Ensembl:
ENSG00000131323
UniProt:
Q13114
Structure
PDB
LinkDB
All DBs
Position
14:102777449..102911500
Genome browser
AA seq
568 aa
AA seq
DB search
MESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVL
CSPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNE
SRGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHC
KSQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLSECVNAPSTCSFKRYGCV
FQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEI
EIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNR
VTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW
KIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRG
EYDALLPWPFKQKVTLMLMDQGSSRRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVFVAQ
TVLENGTYIKDDTIFIKVIVDTSDLPDP
NT seq
1707 nt
NT seq
+upstream
nt +downstream
nt
atggagtcgagtaaaaagatggactctcctggcgcgctgcagactaacccgccgctaaag
ctgcacactgaccgcagtgctgggacgccagtttttgtccctgaacaaggaggttacaag
gaaaagtttgtgaagaccgtggaggacaagtacaagtgtgagaagtgccacctggtgctg
tgcagcccgaagcagaccgagtgtgggcaccgcttctgcgagagctgcatggcggccctg
ctgagctcttcaagtccaaaatgtacagcgtgtcaagagagcatcgttaaagataaggtg
tttaaggataattgctgcaagagagaaattctggctcttcagatctattgtcggaatgaa
agcagaggttgtgcagagcagttaatgctgggacatctgctggtgcatttaaaaaatgat
tgccattttgaagaacttccatgtgtgcgtcctgactgcaaagaaaaggtcttgaggaaa
gacctgcgagaccacgtggagaaggcgtgtaaataccgggaagccacatgcagccactgc
aagagtcaggttccgatgatcgcgctgcagaaacacgaagacaccgactgtccctgcgtg
gtggtgtcctgccctcacaagtgcagcgtccagactctcctgaggagcgagttgagtgca
cacttgtcagagtgtgtcaatgcccccagcacctgtagttttaagcgctatggctgcgtt
tttcaggggacaaaccagcagatcaaggcccacgaggccagctccgccgtgcagcacgtc
aacctgctgaaggagtggagcaactcgctcgaaaagaaggtttccttgttgcagaatgaa
agtgtagaaaaaaacaagagcatacaaagtttgcacaatcagatatgtagctttgaaatt
gaaattgagagacaaaaggaaatgcttcgaaataatgaatccaaaatccttcatttacag
cgagtgatagacagccaagcagagaaactgaaggagcttgacaaggagatccggcccttc
cggcagaactgggaggaagcagacagcatgaagagcagcgtggagtccctccagaaccgc
gtgaccgagctggagagcgtggacaagagcgcggggcaagtggctcggaacacaggcctg
ctggagtcccagctgagccggcatgaccagatgctgagtgtgcacgacatccgcctagcc
gacatggacctgcgcttccaggtcctggagaccgccagctacaatggagtgctcatctgg
aagattcgcgactacaagcggcggaagcaggaggccgtcatggggaagaccctgtccctt
tacagccagcctttctacactggttactttggctataagatgtgtgccagggtctacctg
aacggggacgggatggggaaggggacgcacttgtcgctgttttttgtcatcatgcgtgga
gaatatgatgccctgcttccttggccgtttaagcagaaagtgacactcatgctgatggat
caggggtcctctcgacgtcatttgggagatgcattcaagcccgaccccaacagcagcagc
ttcaagaagcccactggagagatgaatatcgcctctggctgcccagtctttgtggcccaa
actgttctagaaaatgggacatatattaaagatgatacaatttttattaaagtcatagtg
gatacttcggatctgcccgatccctga
Homo sapiens (human): 7188
Help
Entry
7188 CDS
T01001
Symbol
TRAF5, MGC:39780, RNF84
Name
(RefSeq) TNF receptor associated factor 5
KO
K09849
TNF receptor-associated factor 5
Organism
hsa
Homo sapiens (human)
Pathway
hsa04064
NF-kappa B signaling pathway
hsa04217
Necroptosis
hsa04621
NOD-like receptor signaling pathway
hsa04657
IL-17 signaling pathway
hsa04668
TNF signaling pathway
hsa05131
Shigellosis
hsa05163
Human cytomegalovirus infection
hsa05168
Herpes simplex virus 1 infection
hsa05169
Epstein-Barr virus infection
hsa05170
Human immunodeficiency virus 1 infection
hsa05200
Pathways in cancer
hsa05203
Viral carcinogenesis
hsa05222
Small cell lung cancer
Network
nt06160
Human T-cell leukemia virus 1 (HTLV-1)
nt06161
Human immunodeficiency virus 1 (HIV-1)
nt06163
Hepatitis C virus (HCV)
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165
Epstein-Barr virus (EBV)
nt06166
Human papillomavirus (HPV)
nt06167
Human cytomegalovirus (HCMV)
nt06168
Herpes simplex virus 1 (HSV-1)
nt06180
Pathogenic Escherichia coli
nt06181
Salmonella
nt06182
Shigella
nt06223
TNF signaling (cancer)
nt06231
Apoptosis (cancer)
nt06263
Hepatocellular carcinoma
nt06461
Huntington disease
nt06516
TNF signaling
nt06524
Apoptosis
nt06527
Necroptosis
Element
N00145
Extrinsic apoptotic pathway
N00151
TNF-NFKB signaling pathway
N00441
HIV gp120 to TNF-NFKB signaling pathway
N00442
HIV Nef to TNF-NFKB signaling pathway
N00444
TNF-p38 signaling pathway
N00446
TNF-JNK signaling pathway
N00485
EBV LMP1 to PI3K signaling pathway
N00559
LIGHT-HVEM-NFKB signaling pathway
N00560
HSV gD to HVEM-NFKB signaling pathway
N01113
Salmonella SseK1 to TNF-NFKB signaling pathway
N01621
TNF-RIPK1/3 signaling pathway
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
7188 (TRAF5)
04668 TNF signaling pathway
7188 (TRAF5)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
7188 (TRAF5)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
7188 (TRAF5)
04657 IL-17 signaling pathway
7188 (TRAF5)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
7188 (TRAF5)
05203 Viral carcinogenesis
7188 (TRAF5)
09162 Cancer: specific types
05222 Small cell lung cancer
7188 (TRAF5)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
7188 (TRAF5)
05168 Herpes simplex virus 1 infection
7188 (TRAF5)
05163 Human cytomegalovirus infection
7188 (TRAF5)
05169 Epstein-Barr virus infection
7188 (TRAF5)
09171 Infectious disease: bacterial
05131 Shigellosis
7188 (TRAF5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
hsa04121
]
7188 (TRAF5)
Ubiquitin system [BR:
hsa04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
TRAF proteins
7188 (TRAF5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TRAF-mep_MATH
zf-TRAF
TRAF3_RING
zf-C3HC4_2
zf-C3HC4
zf-TRAF_2
Spc29
zf-ACC
Sina_ZnF
zf-RING_6
zf-C3HC4_4
zf-RING_2
ATG16
Paralemmin
zf-RING_UBOX
DUF4941
BORCS8
Acetyltransf_11
PHM7_cyt
Mt_ATP_synt
Motif
Other DBs
NCBI-GeneID:
7188
NCBI-ProteinID:
NP_001029082
OMIM:
602356
HGNC:
12035
Ensembl:
ENSG00000082512
UniProt:
O00463
Structure
PDB
LinkDB
All DBs
Position
1:211326635..211374946
Genome browser
AA seq
557 aa
AA seq
DB search
MAYSEEHKGMPCGFIRQNSGNSISLDFEPSIEYQFVERLEERYKCAFCHSVLHNPHQTGC
GHRFCQHCILSLRELNTVPICPVDKEVIKSQEVFKDNCCKREVLNLYVYCSNAPGCNAKV
ILGRYQDHLQQCLFQPVQCSNEKCREPVLRKDLKEHLSASCQFRKEKCLYCKKDVVVINL
QNHEENLCPEYPVFCPNNCAKIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQQ
HEHSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFG
KNGSFLPNIQVFASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLE
NNDQRLAVLEEETNKHDTHINIHKAQLSKNEERFKLLEGTCYNGKLIWKVTDYKMKKREA
VDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQ
RVTLMLLDQSGKKNIMETFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKD
DTLFLKVAVDLTDLEDL
NT seq
1674 nt
NT seq
+upstream
nt +downstream
nt
atggcttattcagaagagcataaaggtatgccctgtggtttcatccgccagaattccggc
aactccatttccttggactttgagcccagtatagagtaccagtttgtggagcggttggaa
gagcgctacaaatgtgccttctgccactcggtgcttcacaacccccaccagacaggatgt
gggcaccgcttctgccagcactgcatcctgtccctgagagaattaaacacagtgccaatc
tgccctgtagataaagaggtcatcaaatctcaggaggtttttaaagacaattgttgcaaa
agagaagtcctcaacttatatgtatattgcagcaatgctcctggatgtaatgccaaggtt
attctgggccggtaccaggatcaccttcagcagtgcttatttcaacctgtgcagtgttct
aatgagaagtgccgggagccagtcctacggaaagacctgaaagagcatttgagtgcatcc
tgtcagtttcgaaaggaaaaatgcctttattgcaaaaaggatgtggtagtcatcaatcta
cagaatcatgaggaaaacttgtgtcctgaatacccagtattttgtcccaacaattgtgcg
aagattattctaaaaactgaggtagatgaacacctggctgtatgtcctgaagctgagcaa
gactgtccttttaagcactatggctgtgctgtaacggataaacggaggaacctgcagcaa
catgagcattcagccttacgggagcacatgcgtttggttttagaaaagaatgtccaatta
gaagaacagatttctgacttacacaagagcctagaacagaaagaaagtaaaatccagcag
ctagcagaaactataaagaaacttgaaaaggagttcaagcagtttgcacagttgtttggc
aaaaatggaagcttcctcccaaacatccaggtttttgccagtcacattgacaagtcagct
tggctagaagctcaagtgcatcaattattacaaatggttaaccagcaacaaaataaattt
gacctgagacctttgatggaagcagttgatacagtgaaacagaaaattaccctgctagaa
aacaatgatcaaagattagccgttttagaagaggaaactaacaaacatgatacccacatt
aatattcataaagcacagctgagtaaaaatgaagagcgatttaaactgctggagggtact
tgctataatggaaagctcatttggaaggtgacagattacaagatgaagaagagagaggcg
gtggatgggcacacagtgtccatcttcagccagtccttctacaccagccgctgtggctac
cggctctgtgctagagcatacctgaatggggatgggtcagggagggggtcacacctgtcc
ctatactttgtggtcatgcgaggagagtttgactcactgttgcagtggccattcaggcag
agggtgaccctgatgcttctggaccagagtggcaaaaagaacattatggagaccttcaaa
cctgaccccaatagcagcagctttaaaagacctgatggggagatgaacattgcatctggc
tgtccccgctttgtggctcattctgttttggagaatgccaagaacgcctacattaaagat
gacactctgttcttgaaagtggccgtggacttaactgacctggaggatctctag
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integrated database retrieval system
