KEGG ORTHOLOGY: K09849

ORTHOLOGY: K09849

Entry

K09849 KO

Name

TRAF5

Definition

TNF receptor-associated factor 5

Pathway

ko04064

NF-kappa B signaling pathway

ko04217

Necroptosis

ko04621

NOD-like receptor signaling pathway

ko04657

IL-17 signaling pathway

ko04668

TNF signaling pathway

ko05131

Shigellosis

ko05163

Human cytomegalovirus infection

ko05168

Herpes simplex virus 1 infection

ko05169

Epstein-Barr virus infection

ko05170

Human immunodeficiency virus 1 infection

ko05200

Pathways in cancer

ko05203

Viral carcinogenesis

ko05222

Small cell lung cancer

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    K09849  TRAF5; TNF receptor-associated factor 5
   04668 TNF signaling pathway
    K09849  TRAF5; TNF receptor-associated factor 5
09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K09849  TRAF5; TNF receptor-associated factor 5
09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K09849  TRAF5; TNF receptor-associated factor 5
   04657 IL-17 signaling pathway
    K09849  TRAF5; TNF receptor-associated factor 5
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K09849  TRAF5; TNF receptor-associated factor 5
   05203 Viral carcinogenesis
    K09849  TRAF5; TNF receptor-associated factor 5
  09162 Cancer: specific types
   05222 Small cell lung cancer
    K09849  TRAF5; TNF receptor-associated factor 5
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K09849  TRAF5; TNF receptor-associated factor 5
   05168 Herpes simplex virus 1 infection
    K09849  TRAF5; TNF receptor-associated factor 5
   05163 Human cytomegalovirus infection
    K09849  TRAF5; TNF receptor-associated factor 5
   05169 Epstein-Barr virus infection
    K09849  TRAF5; TNF receptor-associated factor 5
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K09849  TRAF5; TNF receptor-associated factor 5
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K09849  TRAF5; TNF receptor-associated factor 5
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  Single Ring-finger type E3
   TRAF proteins
    K09849  TRAF5; TNF receptor-associated factor 5

Genes

HSA:	7188(TRAF5)

PTR:	457711(TRAF5)

PPS:	100978119(TRAF5)

GGO:	101130440(TRAF5)

PON:	100453867(TRAF5)

NLE:	100601779(TRAF5)

MCC:	711879(TRAF5)

MCF:	102142772(TRAF5)

CSAB:

103230138(TRAF5)

CATY:

105577052(TRAF5)

RRO:	104669508(TRAF5)

RBB:	108515877(TRAF5)

TFN:	117074021(TRAF5)

CJC:	100388423(TRAF5)

SBQ:	101031994(TRAF5)

MMUR:

105880516(TRAF5)

MMU:	22033(Traf5)

MCAL:

110296886(Traf5)

MPAH:

110322137(Traf5)

RNO:	684173(Traf5)

MCOC:

116069008(Traf5)

MUN:	110566223(Traf5)

CGE:	100760758(Traf5)

PLEU:

114702410(Traf5)

NGI:	103727039(Traf5)

HGL:	101704164(Traf5)

CCAN:

109692314(Traf5)

OCU:	100340005(TRAF5)

TUP:	102478124(TRAF5)

CFA:	480019(TRAF5)

VVP:	112907150(TRAF5)

AML:	100475872(TRAF5)

UMR:	103672476(TRAF5)

UAH:	113262665(TRAF5)

ORO:	101373241(TRAF5)

ELK:

111150675

MPUF:

101671644(TRAF5)

EJU:	114225907(TRAF5)

FCA:	101086032(TRAF5)

PTG:	102972430(TRAF5)

PPAD:

109254870(TRAF5)

AJU:	106966776(TRAF5)

BTA:	507234(TRAF5)

BOM:	102266053(TRAF5)

BIU:	109570606(TRAF5)

BBUB:

102413198(TRAF5)

CHX:	102188243(TRAF5)

OAS:	101119408(TRAF5)

SSC:	396616(TRAF5)

CFR:	102507430(TRAF5)

CDK:	105099319(TRAF5)

BACU:

103010499(TRAF5)

LVE:	103075051(TRAF5)

OOR:	101280074(TRAF5)

DLE:	111184706(TRAF5)

PCAD:

102986959(TRAF5)

ECB:	100055119(TRAF5)

EPZ:	103551972(TRAF5)

EAI:	106827146(TRAF5)

MYB:	102243439(TRAF5)

MYD:	102764568(TRAF5)

MMYO:

118672932(TRAF5)

MNA:	107538857(TRAF5)

HAI:	109379157(TRAF5)

DRO:	112296542(TRAF5)

SHON:

119004242(TRAF5)

AJM:	119043073(TRAF5)

MMF:	118637497(TRAF5)

PALE:

102879730(TRAF5)

RAY:	107521637(TRAF5)

MJV:	108385436(TRAF5)

LAV:	100663885(TRAF5)

TMU:

101358050

MDO:	100022268(TRAF5)

SHR:	100926831(TRAF5)

PCW:	110222706(TRAF5)

OAA:	100078367(TRAF5)

GGA:	374055(TRAF5)

MGP:	100541595(TRAF5)

CJO:	107311111(TRAF5)

NMEL:

110396762(TRAF5)

APLA:

101797384(TRAF5)

ACYG:

106031523(TRAF5)

TGU:	100219054(TRAF5)

LSR:	110479943(TRAF5)

SCAN:

103821528(TRAF5)

GFR:	102042050(TRAF5)

FAB:	101821791(TRAF5)

PHI:	102104462(TRAF5)

PMAJ:

107201904(TRAF5)

CCAE:

111926165(TRAF5)

CCW:	104685651(TRAF5)

ETL:	114066923(TRAF5)

FPG:	101921400(TRAF5)

FCH:	102053015(TRAF5)

CLV:	102088528(TRAF5)

EGZ:	104128738(TRAF5)

NNI:	104019677(TRAF5)

ACUN:

113478255(TRAF5)

PADL:

103922096(TRAF5)

AAM:	106490486(TRAF5)

ASN:	102370403(TRAF5)

AMJ:	102564531(TRAF5)

PSS:	102459505(TRAF5)

CMY:	102929887(TRAF5)

CPIC:

101933745(TRAF5)

ACS:	100555319(traf5)

PVT:	110079501(TRAF5)

PBI:	103064879(TRAF5)

PMUR:

107288580(TRAF5)

TSR:	106552805(TRAF5)

PMUA:

114594702(TRAF5)

GJA:	107124212(TRAF5)

XLA:	108716445(traf5.L)

XTR:	100491604(traf5)

NPR:	108784349(TRAF5)

DRE:	563887(traf5)

SRX:	107732237 107753499

SANH:

107698239 107702253

SGH:	107550688 107588441

CCAR:

IPU:

PHYP:

AMEX:

EEE:

LCO:

NCC:

MZE:

ONL:

OLA:

KMR:	108249386(traf5)

AOCE:

CSEM:

LCF:

SDU:

SLAL:

MALB:

SASA:

106564804 106585043(TRAF5)

OTW:	112230449 112265803

SALP:

111960656 112070308

ELS:

105026840

SFM:	108933531(traf5)

PKI:	111853469(traf5)

LCM:	102355485(TRAF5)

CMK:	103178011(traf5)

RTP:

BTER:

SOC:

OBO:

PCF:

DPA:

TUT:

EPA:

ADF:	107334241 107338670

AMIL:

114969979

DGT:	114530208 114530330

HMG:	100196987 100211106 101238683 105843481 105845157

AQU:	105312590 105312852 105315220 105315820 109581190 109582161

MTM:	MYCTH_2311696

CTHR:

CTHT_0001550

ELA:	UCREL1_2077

PSCO:

LY89DRAFT_713648

GLZ:	GLAREA_01680

DDI:	DDB_G0268444

DPP:	DICPUDRAFT_73979 DICPUDRAFT_74017 DICPUDRAFT_74976 DICPUDRAFT_76178 DICPUDRAFT_76179

DFA:

DFA_02794

PTM:	GSPATT00021557001 GSPATT00032957001

» show all

Reference

PMID:21822258

Authors

Sun D, Novotny M, Bulek K, Liu C, Li X, Hamilton T

Title

Treatment with IL-17 prolongs the half-life of chemokine CXCL1 mRNA via the adaptor TRAF5 and the splicing-regulatory factor SF2 (ASF).

Journal

Nat Immunol 12:853-60 (2011)
DOI:10.1038/ni.2081

Reference

PMID:9511754

Authors

Mizushima S, Fujita M, Ishida T, Azuma S, Kato K, Hirai M, Otsuka M, Yamamoto T, Inoue J

Title

Cloning and characterization of a cDNA encoding the human homolog of tumor necrosis factor receptor-associated factor 5 (TRAF5).

Journal

Gene 207:135-40 (1998)
DOI:10.1016/S0378-1119(97)00616-1

Sequence

[hsa:7188]

LinkDB

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