KEGG   ORTHOLOGY: K09849
Entry
K09849                      KO                                     
Symbol
TRAF5
Name
TNF receptor-associated factor 5
Pathway
map04064  NF-kappa B signaling pathway
map04217  Necroptosis
map04621  NOD-like receptor signaling pathway
map04657  IL-17 signaling pathway
map04668  TNF signaling pathway
map05131  Shigellosis
map05163  Human cytomegalovirus infection
map05168  Herpes simplex virus 1 infection
map05169  Epstein-Barr virus infection
map05170  Human immunodeficiency virus 1 infection
map05200  Pathways in cancer
map05203  Viral carcinogenesis
map05222  Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    K09849  TRAF5; TNF receptor-associated factor 5
   04668 TNF signaling pathway
    K09849  TRAF5; TNF receptor-associated factor 5
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K09849  TRAF5; TNF receptor-associated factor 5
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K09849  TRAF5; TNF receptor-associated factor 5
   04657 IL-17 signaling pathway
    K09849  TRAF5; TNF receptor-associated factor 5
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K09849  TRAF5; TNF receptor-associated factor 5
   05203 Viral carcinogenesis
    K09849  TRAF5; TNF receptor-associated factor 5
  09162 Cancer: specific types
   05222 Small cell lung cancer
    K09849  TRAF5; TNF receptor-associated factor 5
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K09849  TRAF5; TNF receptor-associated factor 5
   05168 Herpes simplex virus 1 infection
    K09849  TRAF5; TNF receptor-associated factor 5
   05163 Human cytomegalovirus infection
    K09849  TRAF5; TNF receptor-associated factor 5
   05169 Epstein-Barr virus infection
    K09849  TRAF5; TNF receptor-associated factor 5
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K09849  TRAF5; TNF receptor-associated factor 5
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K09849  TRAF5; TNF receptor-associated factor 5
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   TRAF proteins
    K09849  TRAF5; TNF receptor-associated factor 5
Genes
HSA: 7188(TRAF5)
PTR: 457711(TRAF5)
PPS: 100978119(TRAF5)
GGO: 101130440(TRAF5)
PON: 100453867(TRAF5)
PPYG: 129033607(TRAF5)
NLE: 100601779(TRAF5)
HMH: 116457552(TRAF5)
SSYN: 129458211(TRAF5)
MCC: 711879(TRAF5)
MCF: 102142772(TRAF5)
MTHB: 126948771
MNI: 105493576(TRAF5)
CSAB: 103230138(TRAF5)
CATY: 105577052(TRAF5)
PANU: 101024624(TRAF5)
TGE: 112610017(TRAF5)
MLEU: 105536404(TRAF5)
RRO: 104669508(TRAF5)
RBB: 108515877(TRAF5)
TFN: 117074021(TRAF5)
PTEH: 111531090(TRAF5)
CANG: 105509216(TRAF5)
CJC: 100388423(TRAF5)
SBQ: 101031994(TRAF5)
CIMI: 108302141(TRAF5)
ANAN: 105721902(TRAF5)
CSYR: 103260228(TRAF5)
MMUR: 105880516(TRAF5)
LCAT: 123627059(TRAF5)
PCOQ: 105805435(TRAF5)
OGA: 100957799(TRAF5)
MMU: 22033(Traf5)
MCAL: 110296886(Traf5)
MPAH: 110322137(Traf5)
RNO: 684173(Traf5)
MCOC: 116069008(Traf5)
ANU: 117716371(Traf5)
ASYL: 127697876(Traf5)
MUN: 110566223(Traf5)
CGE: 100760758(Traf5)
MAUA: 101838615(Traf5)
PROB: 127223954(Traf5)
PLEU: 114702410(Traf5)
MORG: 121435869(Traf5)
MFOT: 126505400
AAMP: 119827796(Traf5)
NGI: 103727039(Traf5)
HGL: 101704164(Traf5)
CPOC: 100721722(Traf5)
CCAN: 109692314(Traf5)
DORD: 105984909(Traf5)
DSP: 122109749(Traf5)
DMER: 138841077(Traf5)
PLOP: 125359340(Traf5)
NCAR: 124961041
MMMA: 107140575(Traf5)
ITI: 101967109(Traf5)
OCU: 100340005
OPI: 101524603(TRAF5)
TUP: 102478124(TRAF5)
GVR: 103599657(TRAF5)
CFA: 480019(TRAF5)
CLUD: 112648366(TRAF5)
VVP: 112907150(TRAF5)
VLG: 121492435(TRAF5)
NPO: 129505849(TRAF5)
AML: 100475872(TRAF5)
UMR: 103672476(TRAF5)
UAH: 113262665(TRAF5)
UAR: 123785826(TRAF5)
ELK: 111150675
LLV: 125085695
MPUF: 101671644(TRAF5)
MNP: 132025400(TRAF5)
MLK: 131815325(TRAF5)
NVS: 122918546(TRAF5)
ORO: 101373241(TRAF5)
EJU: 114225907(TRAF5)
ZCA: 113933278(TRAF5)
MLX: 118014299(TRAF5)
NSU: 110573917(TRAF5)
LWW: 102740611(TRAF5)
FCA: 101086032(TRAF5)
PYU: 121011741(TRAF5)
PCOO: 112857763(TRAF5)
PBG: 122476367(TRAF5)
PVIV: 125155205(TRAF5)
LRUF: 124510097
LGF: 123584845(TRAF5)
AJU: 106966776
PTG: 102972430(TRAF5)
PPAD: 109254870(TRAF5)
PUC: 125925301
PLEZ: 122211458(TRAF5)
HHV: 120230541(TRAF5)
BTA: 507234(TRAF5)
BOM: 102266053(TRAF5)
BIU: 109570606(TRAF5)
BBUB: 102413198(TRAF5)
BBIS: 104984231(TRAF5)
CHX: 102188243(TRAF5)
OAS: 101119408(TRAF5)
BTAX: 128061711(TRAF5)
CSUM: 138090801(TRAF5)
ODA: 120880035(TRAF5)
CCAD: 122452144(TRAF5)
MREE: 136168602(TRAF5)
OVR: 110129846(TRAF5)
MBEZ: 129551247(TRAF5)
SSC: 396616(TRAF5)
CFR: 102507430(TRAF5)
CBAI: 105064517(TRAF5)
CDK: 105099319(TRAF5)
VPC: 102527879(TRAF5)
BACU: 103010499(TRAF5)
BMUS: 118879828(TRAF5)
LVE: 103075051(TRAF5)
OOR: 101280074(TRAF5)
LALB: 132509632(TRAF5)
GMF: 115861808(TRAF5)
DLE: 111184706(TRAF5)
PCAD: 102986959(TRAF5)
PSIU: 116738804(TRAF5)
PPHC: 136129337(TRAF5)
NASI: 112403568(TRAF5)
ECB: 100055119(TRAF5)
EPZ: 103551972(TRAF5)
EAI: 106827146(TRAF5)
MYB: 102243439(TRAF5)
MYD: 102764568(TRAF5)
MMYO: 118672932(TRAF5)
MLF: 102436664(TRAF5)
MDT: 132221193(TRAF5)
MYUM: 138995870(TRAF5)
PKL: 118721522(TRAF5)
EFUS: 103290060(TRAF5)
MNA: 107538857(TRAF5)
DRO: 112296542(TRAF5)
SHON: 119004242(TRAF5)
AJM: 119043073(TRAF5)
PDIC: 114511917(TRAF5)
PHAS: 123818527(TRAF5)
MMF: 118637497(TRAF5)
PPAM: 129062216(TRAF5)
HAI: 109379157(TRAF5)
RFQ: 117014270(TRAF5)
PALE: 102879730(TRAF5)
PGIG: 120617505(TRAF5)
PVP: 105295002(TRAF5)
RAY: 107521637(TRAF5)
MJV: 108385436(TRAF5)
TOD: 119234414(TRAF5)
LAV: 100663885(TRAF5)
TMU: 101358050
ETF: 101655200(TRAF5)
DNM: 101434084(TRAF5)
MDO: 100022268(TRAF5)
GAS: 123247914(TRAF5)
SHR: 100926831(TRAF5)
AFZ: 127562587
PCW: 110222706(TRAF5)
TVP: 118849057(TRAF5)
PBRV: 138177552(TRAF5)
MLAO: 141513098(TRAF5)
OAA: 100078367(TRAF5)
TACU: 119941025(TRAF5)
GGA: 374055(TRAF5)
PCOC: 116230246(TRAF5)
MGP: 100541595(TRAF5)
CJO: 107311111(TRAF5)
TPAI: 128082152(TRAF5)
LMUT: 125689316(TRAF5)
NMEL: 110396762(TRAF5)
APLA: 101797384(TRAF5)
ACYG: 106031523(TRAF5)
CATA: 118253382(TRAF5)
AFUL: 116488176(TRAF5)
TGU: 100219054(TRAF5)
LSR: 110479943(TRAF5)
SCAN: 103821528(TRAF5)
PMOA: 120496897(TRAF5)
OTC: 121340637(TRAF5)
PRUF: 121358814(TRAF5)
ATRC: 139589789(TRAF5)
GFR: 102042050(TRAF5)
FAB: 101821791(TRAF5)
OMA: 130251003(TRAF5)
PHI: 102104462(TRAF5)
PMAJ: 107201904(TRAF5)
CCAE: 111926165(TRAF5)
CCW: 104685651(TRAF5)
CBRC: 103622703(TRAF5)
ACOE: 138107856(TRAF5)
ETL: 114066923(TRAF5)
ZAB: 102073800(TRAF5)
ZLE: 135445894(TRAF5)
ACHL: 103799235(TRAF5)
SVG: 106853591(TRAF5)
MMEA: 130573002(TRAF5)
HRT: 120750959(TRAF5)
SATI: 136359483(TRAF5)
CCIC: 134042156(TRAF5)
FPG: 101921400(TRAF5)
FCH: 102053015(TRAF5)
CCRI: 104154434
NNT: 104413671(TRAF5)
SHAB: 115614013(TRAF5)
ACUN: 113478255(TRAF5)
TALA: 104359233(TRAF5)
ACHC: 115349818(TRAF5)
HALD: 104317850(TRAF5)
HLE: 104837366(TRAF5)
AGEN: 126052719
HHAR: 128150565(TRAF5)
GCL: 127014283
CSTI: 104549555
LDI: 104349268(TRAF5)
MNB: 103773581(TRAF5)
DPUB: 104297582(TRAF5)
PPUS: 135186597(TRAF5)
AVIT: 104277670(TRAF5)
BRHI: 104491295(TRAF5)
EGZ: 104128738(TRAF5)
NNI: 104019677(TRAF5)
PCRI: 104024317(TRAF5)
PCAO: 104041089(TRAF5)
PADL: 103922096(TRAF5)
AFOR: 103899178(TRAF5)
FGA: 104077706(TRAF5)
GSTE: 104253599(TRAF5)
CBOY: 140649527(TRAF5)
CLV: 102088528(TRAF5)
CNIC: 135986992(TRAF5)
MUI: 104535949(TRAF5)
PGUU: 104458045(TRAF5)
PLET: 104618732(TRAF5)
EHS: 104511489(TRAF5)
CMAC: 104473441(TRAF5)
CUCA: 104058023(TRAF5)
TEO: 104376434(TRAF5)
BREG: 104639800(TRAF5)
OHA: 104327883(TRAF5)
ACAR: 104517421(TRAF5)
CPEA: 104391622(TRAF5)
CVF: 104289397(TRAF5)
RTD: 128906628(TRAF5)
CRID: 134512784(TRAF5)
AAM: 106490486(TRAF5)
AROW: 112969242(TRAF5)
NPD: 112955136(TRAF5)
TGT: 104568745(TRAF5)
DNE: 112989856(TRAF5)
SCAM: 104140281(TRAF5)
ASN: 102370403(TRAF5)
AMJ: 102564531(TRAF5)
CPOO: 109319695(TRAF5)
GGN: 109296824(TRAF5)
PSS: 102459505(TRAF5)
CMY: 102929887(TRAF5)
CCAY: 125633598(TRAF5)
DCC: 119852706(TRAF5)
CPIC: 101933745(TRAF5)
TST: 117874435(TRAF5)
CABI: 116814984(TRAF5)
MRV: 120402445(TRAF5)
ACS: 100555319(traf5)
ASAO: 132761451(TRAF5)
PVT: 110079501(TRAF5)
PBI: 103064879(TRAF5)
PMUR: 107288580(TRAF5)
CTIG: 120315390(TRAF5)
TSR: 106552805(TRAF5)
PGUT: 117671674(TRAF5)
PCAE: 139308665(TRAF5)
APRI: 131189261(TRAF5)
PTEX: 113433296(TRAF5)
NSS: 113422230(TRAF5)
VKO: 123022938(TRAF5)
PMUA: 114594702(TRAF5)
PRAF: 128411169(TRAF5)
ZVI: 118083148(TRAF5)
HCG: 128351111(TRAF5)
GJA: 107124212(TRAF5)
STOW: 125426817(TRAF5)
EMC: 129331658(TRAF5)
XLA: 108716445(traf5.L)
XTR: 100491604(traf5)
NPR: 108784349(TRAF5)
RTEM: 120937931(TRAF5)
ACAT: 141140888(TRAF5)
BBUF: 120999475(TRAF5)
BGAR: 122922944(TRAF5)
DTC: 141056934(TRAF5)
PWL: 138295570(TRAF5)
MUO: 115464250(TRAF5)
GSH: 117357464(TRAF5)
DRE: 563887(traf5)
SRX: 107732237 107753499
SANH: 107698239 107702253
SGH: 107550688 107588441
CCAR: 109047368 109060473
CAUA: 113039731 113065209
CGIB: 127943315 127987033
PTET: 122327270(traf5)
LROH: 127154163(traf5)
GRF: 141338676(traf5)
OMC: 131529626(traf5)
PPRM: 120468714(traf5)
RKG: 130101978(traf5)
MAMB: 125255103
CIDE: 127520774
CERY: 137027622(traf5)
MASI: 127438138 127438701
TROS: 130559868(traf5)
TDW: 130430049(traf5)
MANU: 129453396(traf5)
PDAB: 135740916(traf5)
IPU: 108271110(traf5)
IFU: 128613353(traf5)
PHYP: 113534779
SMEO: 124391062(traf5)
TFD: 113657684(traf5)
TVC: 132853346(traf5)
CGAR: 128542756(traf5)
NGRA: 132899533(traf5)
TRN: 134331598(traf5)
AMEX: 103031120(traf5)
CMAO: 118819514(traf5)
EEE: 113569092
CHAR: 105907631(traf5)
SPIL: 134095475(traf5)
LCO: 104936671
NCC: 104947442
TBEN: 117481733(traf5)
CGOB: 115027296
PGEO: 117449999(traf5)
GACU: 117553440(traf5)
EMAC: 134864101(traf5)
ELY: 117255650(traf5)
EFO: 125886130(traf5)
PLEP: 121942134(traf5)
SLUC: 116048148(traf5)
PFLV: 114546386
GAT: 120825302(traf5)
PPUG: 119217931(traf5)
AFB: 129095574(traf5)
CLUM: 117750140(traf5)
CANA: 137792891(traf5)
CVE: 137884806(traf5)
MSAM: 119899952
SCHU: 122873045(traf5)
CUD: 121508809(traf5)
SPUL: 138594814(traf5)
LMIX: 132993943(traf5)
ALAT: 119023819(traf5)
MZE: 101481248
ONL: 100697176
OAU: 116326583(traf5)
OLA: 101170323
OML: 112157264(traf5)
CSAI: 133447461(traf5)
KMR: 108249386(traf5)
AOCE: 111563258(traf5)
MCEP: 125003547(traf5)
CSEM: 103383406
SSEN: 122762305(traf5)
SSOE: 131466779(traf5)
SMAU: 118312887(traf5)
LCF: 108892171(traf5)
SDU: 111232930
SLAL: 111649752
XGL: 120799791(traf5)
MALB: 109971816
BSPL: 114860027(traf5)
SJO: 128378226(traf5)
SSCO: 133999674(traf5)
SASA: 106564804 106585043(TRAF5)
STRU: 115178274 115208506
OTW: 112230449(traf5) 112265814
OMY: 110486074 110493771
OGO: 124002870 124002871 124016465
ONE: 115103970
OKI: 109875526 109890153
OKE: 118365071(traf5)
OMM: 135521009
OCLA: 139423880
SALP: 111960656 112070308
SNH: 120022465(traf5) 120033051
CCLU: 121572365(traf5) 123490781
ELS: 105026840
OEP: 134008978(traf5)
SFM: 108933531(traf5)
PKI: 111853469(traf5)
AANG: 118221762(traf5)
CCOG: 133121962(traf5)
LOC: 102698366(traf5)
PSPA: 121316160(traf5) 121317294
ARUT: 117402571 117411504
PSEX: 120516665(traf5)
LCM: 102355485(TRAF5)
CMK: 103178011
RTP: 109920924
CPLA: 122552801
HOC: 132819400
LERI: 129699700
HAKA: 140730413
BBEL: 109465918
OFU: 114366247
DSV: 119431967 119452895 119453015 119460671 119464227 119464231
RSAN: 119379109 119388951 119401552 119401571 119402313 119402483 119406443
RMP: 119159949 119161081 119163659 119163663 119163664 119163906 119163907 119164153 119164172 119164482 119164957 119176117 119185589 119187252
VDE: 111246021
VJA: 111266134
GOE: 100900168
TUT: 107368829
DPOL: 127872910
EPA: 110251088
ATEN: 116289186 116293251 116300688 116307189
ADF: 107334241 107338670
AMIL: 114954881 114956144 114972576 122952109 122960747
MCAZ: 138049409 138049410 138049411
MFOO: 137984692
DGT: 114530208 114530330
XEN: 124448782 124449680 124457012
HMG: 100211106 101238683 105843481 105845157
HSY: 130629611 130641213
AQU: 105312590 105312852 105315220 105315820 109581190 109582161
DDI: DDB_G0268444
DPP: DICPUDRAFT_76179
PTM: GSPATT00032957001
 » show all
Reference
PMID:21822258
  Authors
Sun D, Novotny M, Bulek K, Liu C, Li X, Hamilton T
  Title
Treatment with IL-17 prolongs the half-life of chemokine CXCL1 mRNA via the adaptor TRAF5 and the splicing-regulatory factor SF2 (ASF).
  Journal
Nat Immunol 12:853-60 (2011)
DOI:10.1038/ni.2081
Reference
PMID:9511754
  Authors
Mizushima S, Fujita M, Ishida T, Azuma S, Kato K, Hirai M, Otsuka M, Yamamoto T, Inoue J
  Title
Cloning and characterization of a cDNA encoding the human homolog of tumor necrosis factor receptor-associated factor 5 (TRAF5).
  Journal
Gene 207:135-40 (1998)
DOI:10.1016/S0378-1119(97)00616-1
  Sequence
[hsa:7188]
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