KEGG   PATHWAY: leri00562
Entry
leri00562                   Pathway                                
Name
Inositol phosphate metabolism - Leucoraja erinacea (little skate)
Class
Metabolism; Carbohydrate metabolism
Pathway map
leri00562  Inositol phosphate metabolism
leri00562

Module
leri_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 [PATH:leri00562]
leri_M00131  Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol [PATH:leri00562]
leri_M00132  Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate [PATH:leri00562]
Other DBs
GO: 0006020
Organism
Leucoraja erinacea (little skate) [GN:leri]
Gene
129695860  pik3c3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1 [KO:K00914] [EC:2.7.1.137]
129702307  mtm1; myotubularin [KO:K01108] [EC:3.1.3.64 3.1.3.95]
129702306  mtmr1b; myotubularin-related protein 1b isoform X1 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
129698276  mtmr2; myotubularin-related protein 2 [KO:K18081] [EC:3.1.3.64 3.1.3.95]
129709349  mtmr3; myotubularin-related protein 3 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
129710765  mtmr4; myotubularin-related protein 4 isoform X1 [KO:K18082] [EC:3.1.3.48 3.1.3.64 3.1.3.95]
129702054  mtmr8; myotubularin-related protein 8 isoform X1 [KO:K18083] [EC:3.1.3.64 3.1.3.95]
129697165  mtmr7b; myotubularin-related protein 7b [KO:K18083] [EC:3.1.3.64 3.1.3.95]
129698079  myotubularin-related protein 6-like [KO:K18083] [EC:3.1.3.64 3.1.3.95]
129704767  mtmr14; myotubularin-related protein 14 isoform X1 [KO:K18086] [EC:3.1.3.64 3.1.3.95]
129709215  pi4kab; phosphatidylinositol 4-kinase, catalytic, alpha b [KO:K00888] [EC:2.7.1.67]
129715594  pi4kb; phosphatidylinositol 4-kinase beta [KO:K19801] [EC:2.7.1.67]
129698823  pi4k2b; phosphatidylinositol 4-kinase type 2-beta [KO:K13711] [EC:2.7.1.67]
129704149  pi4k2a; phosphatidylinositol 4-kinase type 2-alpha [KO:K13711] [EC:2.7.1.67]
129711218  phosphatidylinositol-3-phosphatase SAC1-like isoform X1 [KO:K21797] [EC:3.1.3.-]
129704016  inpp5f; phosphatidylinositide phosphatase SAC2 [KO:K21798] [EC:3.1.3.-]
129695518  phosphatidylinositol 4-phosphate 5-kinase type-1 beta-like isoform X1 [KO:K00889] [EC:2.7.1.68]
129710964  phosphatidylinositol 4-phosphate 5-kinase type-1 gamma-like isoform X1 [KO:K00889] [EC:2.7.1.68]
129694519  putative PIP5K1A and PSMD4-like protein [KO:K00889] [EC:2.7.1.68]
129712036  pip5kl1; phosphatidylinositol 4-phosphate 5-kinase-like protein 1 [KO:K13712] [EC:2.7.1.68]
129702138  ocrl; inositol polyphosphate 5-phosphatase OCRL isoform X1 [KO:K01099] [EC:3.1.3.36]
129709616  inpp5b; type II inositol 1,4,5-trisphosphate 5-phosphatase isoform X1 [KO:K01099] [EC:3.1.3.36]
129712086  inpp5e; phosphatidylinositol polyphosphate 5-phosphatase type IV [KO:K20278] [EC:3.1.3.36]
129702487  synj1; synaptojanin-1 [KO:K20279] [EC:3.1.3.36]
129699841  synaptojanin-2-like [KO:K20279] [EC:3.1.3.36]
129699284  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858] [EC:3.1.4.11]
129699288  LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 [KO:K05858] [EC:3.1.4.11]
129700502  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2-like [KO:K05858] [EC:3.1.4.11]
129715851  LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1-like [KO:K05858] [EC:3.1.4.11]
129705453  plcd1a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1a isoform X1 [KO:K05857] [EC:3.1.4.11]
129710237  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-like [KO:K05857] [EC:3.1.4.11]
129710252  LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3-like [KO:K05857] [EC:3.1.4.11]
129715559  LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4-like [KO:K05857] [EC:3.1.4.11]
129703897  plce1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1 [KO:K05860] [EC:3.1.4.11]
129696002  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like [KO:K01116] [EC:3.1.4.11]
129707265  plcg1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [KO:K01116] [EC:3.1.4.11]
129705387  plcg2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [KO:K05859] [EC:3.1.4.11]
129707688  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1-like [KO:K05861] [EC:3.1.4.11]
129703654  plch1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 isoform X1 [KO:K19006] [EC:3.1.4.11]
129711607  plch2a; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2a isoform X1 [KO:K19006] [EC:3.1.4.11]
129697517  LOW QUALITY PROTEIN: inositol-trisphosphate 3-kinase B-like [KO:K00911] [EC:2.7.1.127]
129700412  itpka; inositol-trisphosphate 3-kinase A [KO:K00911] [EC:2.7.1.127]
129714231  itpkca; inositol-trisphosphate 3-kinase C isoform X1 [KO:K00911] [EC:2.7.1.127]
129704251  minpp1b; multiple inositol polyphosphate phosphatase 1b isoform X1 [KO:K03103] [EC:3.1.3.62 3.1.3.80]
129713399  inositol polyphosphate-5-phosphatase A-like [KO:K01106] [EC:3.1.3.56]
129703927  inositol polyphosphate-5-phosphatase A [KO:K01106] [EC:3.1.3.56]
129709143  inpp5jb; phosphatidylinositol 4,5-bisphosphate 5-phosphatase A isoform X1 [KO:K24222] [EC:3.1.3.56]
129710617  inositol polyphosphate 5-phosphatase K-like [KO:K24222] [EC:3.1.3.56]
129698639  inositol polyphosphate 1-phosphatase-like [KO:K01107] [EC:3.1.3.57]
129714750  inpp1; inositol polyphosphate 1-phosphatase [KO:K01107] [EC:3.1.3.57]
129696374  impa1; inositol monophosphatase 1 isoform X1 [KO:K01092] [EC:3.1.3.25]
129696465  impa2; inositol monophosphatase 2 [KO:K01092] [EC:3.1.3.25]
129699961  itpk1a; inositol-tetrakisphosphate 1-kinase [KO:K00913] [EC:2.7.1.159 2.7.1.134]
129714116  inositol-tetrakisphosphate 1-kinase-like [KO:K00913] [EC:2.7.1.159 2.7.1.134]
129714118  inositol-tetrakisphosphate 1-kinase-like [KO:K00913] [EC:2.7.1.159 2.7.1.134]
129704244  ipmkb; inositol polyphosphate multikinase [KO:K00915] [EC:2.7.1.140 2.7.1.151]
129704874  ippk; inositol-pentakisphosphate 2-kinase [KO:K10572] [EC:2.7.1.158]
129697859  inositol polyphosphate-4-phosphatase type I A-like isoform X1 [KO:K01109] [EC:3.1.3.66]
129704565  inpp4b; LOW QUALITY PROTEIN: type II inositol 3,4-bisphosphate 4-phosphatase [KO:K01109] [EC:3.1.3.66]
129711047  inositol-3-phosphate synthase 1-B-like isoform X1 [KO:K01858] [EC:5.5.1.4]
129703732  pik3cb; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [KO:K00922] [EC:2.7.1.153]
129711734  pik3cd; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform [KO:K00922] [EC:2.7.1.153]
129704660  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform-like [KO:K21289] [EC:2.7.1.153]
129708408  pik3cg; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform [KO:K21289] [EC:2.7.1.153]
129704256  ptenb; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [KO:K01110] [EC:3.1.3.16 3.1.3.48 3.1.3.67]
129703549  inpp5d; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1 [KO:K03084] [EC:3.1.3.86]
129694770  inppl1a; LOW QUALITY PROTEIN: phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2A [KO:K15909] [EC:3.1.3.86]
129702347  phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2A-like [KO:K15909] [EC:3.1.3.86]
129708865  pik3c2b; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [KO:K00923] [EC:2.7.1.154]
129705938  pik3c2a; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha [KO:K00923] [EC:2.7.1.154]
129707687  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta-like [KO:K00923] [EC:2.7.1.154]
129698571  pikfyve; 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1 [KO:K00921] [EC:2.7.1.150]
129696880  fig4a; polyphosphoinositide phosphatase isoform X1 [KO:K22913] [EC:3.1.3.-]
129710095  phosphatidylinositol 5-phosphate 4-kinase type-2 beta-like isoform X1 [KO:K00920] [EC:2.7.1.149]
129707458  phosphatidylinositol 5-phosphate 4-kinase type-2 alpha [KO:K00920] [EC:2.7.1.149]
129704806  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase isoform X1 [KO:K00999] [EC:2.7.8.11]
129707833  miox; inositol oxygenase isoform X1 [KO:K00469] [EC:1.13.99.1]
129700013  aldh6a1; methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial [KO:K00140] [EC:1.2.1.18 1.2.1.27]
Compound
C00024  Acetyl-CoA
C00092  D-Glucose 6-phosphate
C00111  Glycerone phosphate
C00118  D-Glyceraldehyde 3-phosphate
C00137  myo-Inositol
C00191  D-Glucuronate
C00222  3-Oxopropanoate
C00558  D-Tagaturonate
C00641  1,2-Diacyl-sn-glycerol
C00691  2,4,6/3,5-Pentahydroxycyclohexanone
C01177  Inositol 1-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01204  Phytic acid
C01220  1D-myo-Inositol 1,4-bisphosphate
C01243  1D-myo-Inositol 1,3,4-trisphosphate
C01245  D-myo-Inositol 1,4,5-trisphosphate
C01272  1D-myo-Inositol 1,3,4,5-tetrakisphosphate
C01277  1-Phosphatidyl-1D-myo-inositol 4-phosphate
C01284  1D-myo-Inositol 1,3,4,5,6-pentakisphosphate
C03546  myo-Inositol 4-phosphate
C03659  D-Bornesitol
C03660  L-Bornesitol
C04006  1D-myo-Inositol 3-phosphate
C04062  D-myo-Inositol 1,3-bisphosphate
C04063  D-myo-Inositol 3,4-bisphosphate
C04287  3D-3,5/4-Trihydroxycyclohexane-1,2-dione
C04477  1D-myo-Inositol 1,3,4,6-tetrakisphosphate
C04520  1D-myo-Inositol 3,4,5,6-tetrakisphosphate
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04563  D-myo-Inositol 1,2,4,5,6-pentakisphosphate
C04579  Inositol 1,2,3,5,6-pentakisphosphate
C04637  1-Phosphatidyl-D-myo-inositol 4,5-bisphosphate
C05981  Phosphatidylinositol-3,4,5-trisphosphate
C06153  scyllo-Inositol
C06892  2-Deoxy-5-keto-D-gluconic acid
C06893  2-Deoxy-5-keto-D-gluconic acid 6-phosphate
C11554  1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate
C11555  1D-myo-Inositol 1,4,5,6-tetrakisphosphate
C11556  1-Phosphatidyl-1D-myo-inositol 3,5-bisphosphate
C11557  1-Phosphatidyl-1D-myo-inositol 5-phosphate
C16737  5-Deoxy-D-glucuronate
C19794  CDP-1L-myo-inositol
C19799  Bis(1L-myo-inositol)-3,1'-phosphate 1-phosphate
C19891  1D-chiro-Inositol
C20251  1-Keto-D-chiro-inositol
C21643  3-Dehydro-scyllo-inosose
C21644  5-Dehydro-L-gluconate
Reference
PMID:14993306
  Authors
Yoshida K, Yamaguchi M, Ikeda H, Omae K, Tsurusaki K, Fujita Y
  Title
The fifth gene of the iol operon of Bacillus subtilis, iolE, encodes 2-keto-myo-inositol dehydratase.
  Journal
Microbiology 150:571-80 (2004)
DOI:10.1099/mic.0.26768-0
Reference
PMID:18310071
  Authors
Yoshida K, Yamaguchi M, Morinaga T, Kinehara M, Ikeuchi M, Ashida H, Fujita Y.
  Title
myo-Inositol catabolism in Bacillus subtilis.
  Journal
J Biol Chem 283:10415-24 (2008)
DOI:10.1074/jbc.M708043200
Related
pathway
leri00010  Glycolysis / Gluconeogenesis
leri00020  Citrate cycle (TCA cycle)
leri00040  Pentose and glucuronate interconversions
leri00564  Glycerophospholipid metabolism
KO pathway
ko00562   
LinkDB

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