KEGG   PATHWAY: mlx00513
Entry
mlx00513                    Pathway                                
Name
Various types of N-glycan biosynthesis - Mirounga leonina (Southern elephant seal)
Class
Metabolism; Glycan biosynthesis and metabolism
Pathway map
mlx00513  Various types of N-glycan biosynthesis
mlx00513

Module
mlx_M00072  N-glycosylation by oligosaccharyltransferase [PATH:mlx00513]
Other DBs
GO: 0006487
Organism
Mirounga leonina (Southern elephant seal) [GN:mlx]
Gene
117997755  ALG12; dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase [KO:K03847] [EC:2.4.1.260]
117998461  [KO:K00730]
117998923  MGAT4C; alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C [KO:K13748] [EC:2.4.1.201 2.4.1.145]
118000469  MAN1A2; mannosyl-oligosaccharide 1,2-alpha-mannosidase IB isoform X1 [KO:K01230] [EC:3.2.1.113]
118000541  MAN1B1; endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase [KO:K23741]
118000625  MAN1A1; mannosyl-oligosaccharide 1,2-alpha-mannosidase IA [KO:K01230] [EC:3.2.1.113]
118002345  FUT8; alpha-(1,6)-fucosyltransferase [KO:K00717] [EC:2.4.1.68]
118002592  MGAT2; alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase [KO:K00736] [EC:2.4.1.143]
118002645  STT3B; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B [KO:K07151] [EC:2.4.99.18]
118003056  DAD1; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 [KO:K12668]
118003676  HEXA; beta-hexosaminidase subunit alpha isoform X1 [KO:K12373] [EC:3.2.1.52]
118004748  CHST9; carbohydrate sulfotransferase 9 [KO:K09673] [EC:2.8.2.-]
118004944  RPN1; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 [KO:K12666]
118006891  ALG3; dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase isoform X1 [KO:K03845] [EC:2.4.1.258]
118007682  OST4; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 [KO:K00730]
118008225  MGAT4A; alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A isoform X1 [KO:K00738] [EC:2.4.1.145]
118008411  [KO:K00730]
118009470  ALG11; GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase isoform X1 [KO:K03844] [EC:2.4.1.131]
118010024  TUSC3; tumor suppressor candidate 3 isoform X1 [KO:K19478]
118011459  RPN2; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform X1 [KO:K12667]
118012103  [KO:K03847] [EC:2.4.1.260]
118012126  ALG13; LOW QUALITY PROTEIN: putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 [KO:K07432] [EC:2.4.1.141]
118013221  ALG9; alpha-1,2-mannosyltransferase ALG9 isoform X1 [KO:K03846] [EC:2.4.1.259 2.4.1.261]
118013369  STT3A; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A [KO:K07151] [EC:2.4.99.18]
118013876  KRTCAP2; keratinocyte-associated protein 2 isoform X1 [KO:K28202]
118014013  B4GALT3; beta-1,4-galactosyltransferase 3 isoform X1 [KO:K07968] [EC:2.4.1.90 2.4.1.38 2.4.1.-]
118015665  B4GALNT4; N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 [KO:K09657] [EC:2.4.1.244]
118015926  TMEM258; transmembrane protein 258 [KO:K26502]
118017134  HEXB; beta-hexosaminidase subunit beta [KO:K12373] [EC:3.2.1.52]
118017897  ALG2; alpha-1,3/1,6-mannosyltransferase ALG2 [KO:K03843] [EC:2.4.1.132 2.4.1.257]
118018025  B4GALT1; beta-1,4-galactosyltransferase 1 isoform X1 [KO:K07966] [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
118019110  ALG14; UDP-N-acetylglucosamine transferase subunit ALG14 homolog isoform X1 [KO:K07441] [EC:2.4.1.141]
118019513  B4GALT2; beta-1,4-galactosyltransferase 2 isoform X1 [KO:K07967] [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
118019518  ST3GAL3; CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X1 [KO:K00781] [EC:2.4.3.6]
118019859  MAN1C1; mannosyl-oligosaccharide 1,2-alpha-mannosidase IC isoform X1 [KO:K01230] [EC:3.2.1.113]
118019926  DDOST; dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit [KO:K12670]
118021806  ALG1; chitobiosyldiphosphodolichol beta-mannosyltransferase isoform X1 [KO:K03842] [EC:2.4.1.142]
118022549  MGAT4D; alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D [KO:K00738] [EC:2.4.1.145]
118022723  CHST8; carbohydrate sulfotransferase 8 [KO:K09672] [EC:2.8.2.-]
118023074  MAN2A2; alpha-mannosidase 2x isoform X1 [KO:K01231] [EC:3.2.1.114]
118024140  HEXD; hexosaminidase D isoform X1 [KO:K14459] [EC:3.2.1.52]
118025451  B4GALNT3; beta-1,4-N-acetylgalactosaminyltransferase 3 [KO:K09656] [EC:2.4.1.244]
118026048  MAGT1; magnesium transporter protein 1 [KO:K19478]
118026512  MGAT4B; alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B isoform X1 [KO:K00738] [EC:2.4.1.145]
118026533  MGAT1; alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase [KO:K00726] [EC:2.4.1.101]
118027082  OSTC; oligosaccharyltransferase complex subunit OSTC [KO:K26501]
Compound
G00011  
G00012  
G00013  
G00014  
G00015  
G00016  Core fucose
G00017  
G00179  
G01813  
G05477  
G10665  
G10694  
G10716  
G10770  
G10841  
G10920  
G11000  
G11040  
G11933  
G12617  
G12625  
G12626  
G13047  
G13048  
G13049  
G13050  
G13055  
G13056  
G13057  
G13058  
G13059  
Reference
PMID:11412862
  Authors
Munro S.
  Title
What can yeast tell us about N-linked glycosylation in the Golgi apparatus?
  Journal
FEBS Lett 498:223-7 (2001)
DOI:10.1016/S0014-5793(01)02488-7
Reference
PMID:9878803
  Authors
Dean N.
  Title
Asparagine-linked glycosylation in the yeast Golgi.
  Journal
Biochim Biophys Acta 1426:309-22 (1999)
DOI:10.1016/S0304-4165(98)00132-9
Reference
PMID:9878780
  Authors
Herscovics A.
  Title
Processing glycosidases of Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1426:275-85 (1999)
DOI:10.1016/S0304-4165(98)00129-9
Reference
PMID:9218445
  Authors
Wang XH, Nakayama K, Shimma Y, Tanaka A, Jigami Y.
  Title
MNN6, a member of the KRE2/MNT1 family, is the gene for mannosylphosphate transfer in Saccharomyces cerevisiae.
  Journal
J Biol Chem 272:18117-24 (1997)
DOI:10.1074/jbc.272.29.18117
Reference
PMID:9756928
  Authors
Rayner JC, Munro S.
  Title
Identification of the MNN2 and MNN5 mannosyltransferases required for forming and extending the mannose branches of the outer chain mannans of Saccharomyces cerevisiae.
  Journal
J Biol Chem 273:26836-43 (1998)
DOI:10.1074/jbc.273.41.26836
Reference
PMID:10037752
  Authors
Jungmann J, Rayner JC, Munro S.
  Title
The Saccharomyces cerevisiae protein Mnn10p/Bed1p is a subunit of a Golgi mannosyltransferase complex.
  Journal
J Biol Chem 274:6579-85 (1999)
DOI:10.1074/jbc.274.10.6579
Reference
PMID:8253757
  Authors
Nakanishi-Shindo Y, Nakayama K, Tanaka A, Toda Y, Jigami Y.
  Title
Structure of the N-linked oligosaccharides that show the complete loss of alpha-1,6-polymannose outer chain from och1, och1 mnn1, and och1 mnn1 alg3 mutants of Saccharomyces cerevisiae.
  Journal
J Biol Chem 268:26338-45 (1993)
Reference
PMID:20233335
  Authors
Gomord V, Fitchette AC, Menu-Bouaouiche L, Saint-Jore-Dupas C, Plasson C, Michaud D, Faye L
  Title
Plant-specific glycosylation patterns in the context of therapeutic protein production.
  Journal
Plant Biotechnol J 8:564-87 (2010)
DOI:10.1111/j.1467-7652.2009.00497.x
Related
pathway
mlx00510  N-Glycan biosynthesis
KO pathway
ko00513   

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