KEGG   PATHWAY: ko00513
Entry
ko00513                     Pathway                                
Name
Various types of N-glycan biosynthesis
Class
Metabolism; Glycan biosynthesis and metabolism
Pathway map
ko00513  Various types of N-glycan biosynthesis
ko00513

Module
M00072  N-glycosylation by oligosaccharyltransferase [PATH:ko00513]
M00074  N-glycan biosynthesis, high-mannose type [PATH:ko00513]
Other DBs
GO: 0006487
Orthology
K00717  FUT8; glycoprotein 6-alpha-L-fucosyltransferase [EC:2.4.1.68]
K00726  MGAT1; alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase [EC:2.4.1.101]
K00730  OST4; dolichyl-diphosphooligosaccharide---protein glycosyltransferase subunit 4
K00736  MGAT2; alpha-1,6-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase [EC:2.4.1.143]
K00738  MGAT4A_B; alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase A/B [EC:2.4.1.145]
K00753  E2.4.1.214; glycoprotein 3-alpha-L-fucosyltransferase [EC:2.4.1.214]
K00781  ST3GAL3; N-acetyllactosaminide alpha-2,3-sialyltransferase (sialyltransferase 6) [EC:2.4.3.6]
K01230  MAN1A_C, MNS1_2; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
K01231  MAN2; alpha-mannosidase II [EC:3.2.1.114]
K03714  XYLT; glycoprotein 2-beta-D-xylosyltransferase [EC:2.4.2.38]
K03842  ALG1; beta-1,4-mannosyltransferase [EC:2.4.1.142]
K03843  ALG2; alpha-1,3/alpha-1,6-mannosyltransferase [EC:2.4.1.132 2.4.1.257]
K03844  ALG11; alpha-1,2-mannosyltransferase [EC:2.4.1.131]
K03845  ALG3; alpha-1,3-mannosyltransferase [EC:2.4.1.258]
K03846  ALG9; alpha-1,2-mannosyltransferase [EC:2.4.1.259 2.4.1.261]
K03847  ALG12; alpha-1,6-mannosyltransferase [EC:2.4.1.260]
K05528  OCH1; alpha 1,6-mannosyltransferase [EC:2.4.1.232]
K05529  MNN9; mannan polymerase complexes MNN9 subunit [EC:2.4.1.232]
K05530  VAN1; mannan polymerase I complex VAN1 subunit [EC:2.4.1.-]
K05531  MNN10; mannan polymerase II complex MNN10 subunit [EC:2.4.1.-]
K05532  MNN11; mannan polymerase II complex MNN11 subunit [EC:2.4.1.-]
K05533  ANP1; mannan polymerase II complex ANP1 subunit [EC:2.4.1.-]
K05534  HOC1; mannan polymerase II complex HOC1 subunit [EC:2.4.1.-]
K05535  MNN2; alpha 1,2-mannosyltransferase [EC:2.4.1.-]
K05536  MNN5; alpha 1,2-mannosyltransferase [EC:2.4.1.-]
K05537  KTR6; mannosylphosphate transferase [EC:2.7.8.-]
K05538  MNN1; alpha 1,3-mannosyltransferase [EC:2.4.1.-]
K07151  STT3; dolichyl-diphosphooligosaccharide---protein glycosyltransferase [EC:2.4.99.18]
K07432  ALG13; beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.141]
K07441  ALG14; beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.141]
K07966  B4GALT1; beta-1,4-galactosyltransferase 1 [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
K07967  B4GALT2; beta-1,4-galactosyltransferase 2 [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
K07968  B4GALT3; beta-1,4-galactosyltransferase 3 [EC:2.4.1.90 2.4.1.38 2.4.1.-]
K09656  B4GALNT3; beta-1,4-N-acetylgalactosaminyltransferase 3 [EC:2.4.1.244]
K09657  B4GALNT4; beta-1,4-N-acetylgalactosaminyltransferase 4 [EC:2.4.1.244]
K09672  CHST8; carbohydrate 4-sulfotransferase 8 [EC:2.8.2.-]
K09673  CHST9; carbohydrate 4-sulfotransferase 9 [EC:2.8.2.-]
K12373  HEXA_B; hexosaminidase [EC:3.2.1.52]
K12666  RPN1, OST1; dolichyl-diphosphooligosaccharide---protein glycosyltransferase subunit 1 (ribophorin I)
K12667  RPN2, SWP1; dolichyl-diphosphooligosaccharide---protein glycosyltransferase subunit 2 (ribophorin II)
K12668  DAD1, OST2; dolichyl-diphosphooligosaccharide---protein glycosyltransferase subunit DAD1/OST2
K12669  OST3_6; dolichyl-diphosphooligosaccharide---protein glycosyltransferase subunit 3/6
K12670  DDOST, WBP1; dolichyl-diphosphooligosaccharide---protein glycosyltransferase subunit DDOST/WBP1
K12691  OST5; dolichyl-diphosphooligosaccharide---protein glycosyltransferase subunit 5
K13748  MGAT4C; alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase C [EC:2.4.1.201 2.4.1.145]
K14412  FUT13, FucTC; alpha-1,4-fucosyltransferase [EC:2.4.1.65]
K14413  GALT1; beta-1,3-galactosyltransferase [EC:2.4.1.-]
K14434  GALT-1; alpha 1,6-fucoside beta 1,4-galactosyltransferase [EC:2.4.1.-]
K14459  HEX; hexosaminidase [EC:3.2.1.52]
K14464  FUT-1, FucTC; alpha-1,3-fucosyltransferase [EC:2.4.1.-]
K19478  MAGT1, TUSC3; dolichyl-diphosphooligosaccharide---protein glycosyltransferase subunit MAGT1/TUSC3
K20730  FDL; beta-hexosaminidase Fdl [EC:3.2.1.52]
K23741  MAN1B, MNS3; endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase
K26501  OSTC; oligosaccharyltransferase complex subunit OSTC
K26502  TMEM258; transmembrane protein 258
K28202  KRTCAP2, KCP2; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2
Compound
G00011  
G00012  
G00013  
G00014  
G00015  
G00016  Core fucose
G00017  
G00179  
G01813  
G05477  
G10665  
G10694  
G10716  
G10770  
G10841  
G10920  
G11000  
G11040  
G11933  
G12617  
G12625  
G12626  
G13047  
G13048  
G13049  
G13050  
G13055  
G13056  
G13057  
G13058  
G13059  
Reference
  Authors
Munro S.
  Title
What can yeast tell us about N-linked glycosylation in the Golgi apparatus?
  Journal
FEBS Lett 498:223-7 (2001)
DOI:10.1016/S0014-5793(01)02488-7
Reference
PMID:9878803
  Authors
Dean N.
  Title
Asparagine-linked glycosylation in the yeast Golgi.
  Journal
Biochim Biophys Acta 1426:309-22 (1999)
DOI:10.1016/S0304-4165(98)00132-9
Reference
PMID:9878780
  Authors
Herscovics A.
  Title
Processing glycosidases of Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1426:275-85 (1999)
DOI:10.1016/S0304-4165(98)00129-9
Reference
PMID:9218445
  Authors
Wang XH, Nakayama K, Shimma Y, Tanaka A, Jigami Y.
  Title
MNN6, a member of the KRE2/MNT1 family, is the gene for mannosylphosphate transfer in Saccharomyces cerevisiae.
  Journal
J Biol Chem 272:18117-24 (1997)
DOI:10.1074/jbc.272.29.18117
Reference
PMID:9756928
  Authors
Rayner JC, Munro S.
  Title
Identification of the MNN2 and MNN5 mannosyltransferases required for forming and extending the mannose branches of the outer chain mannans of Saccharomyces cerevisiae.
  Journal
J Biol Chem 273:26836-43 (1998)
DOI:10.1074/jbc.273.41.26836
Reference
  Authors
Jungmann J, Rayner JC, Munro S.
  Title
The Saccharomyces cerevisiae protein Mnn10p/Bed1p is a subunit of a Golgi mannosyltransferase complex.
  Journal
J Biol Chem 274:6579-85 (1999)
DOI:10.1074/jbc.274.10.6579
Reference
PMID:8253757
  Authors
Nakanishi-Shindo Y, Nakayama K, Tanaka A, Toda Y, Jigami Y.
  Title
Structure of the N-linked oligosaccharides that show the complete loss of alpha-1,6-polymannose outer chain from och1, och1 mnn1, and och1 mnn1 alg3 mutants of Saccharomyces cerevisiae.
  Journal
J Biol Chem 268:26338-45 (1993)
Reference
  Authors
Gomord V, Fitchette AC, Menu-Bouaouiche L, Saint-Jore-Dupas C, Plasson C, Michaud D, Faye L
  Title
Plant-specific glycosylation patterns in the context of therapeutic protein production.
  Journal
Plant Biotechnol J 8:564-87 (2010)
DOI:10.1111/j.1467-7652.2009.00497.x
Related
pathway
ko00510  N-Glycan biosynthesis

DBGET integrated database retrieval system