KEGG   PATHWAY: npm00230
Entry
npm00230                    Pathway                                
Name
Purine metabolism - Neorhizobium petrolearium
Class
Metabolism; Nucleotide metabolism
Pathway map
npm00230  Purine metabolism
npm00230

Module
npm_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:npm00230]
npm_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:npm00230]
npm_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:npm00230]
npm_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:npm00230]
npm_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:npm00230]
npm_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:npm00230]
Other DBs
GO: 0006163 0042278
Organism
Neorhizobium petrolearium [GN:npm]
Gene
QEO92_26010  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
QEO92_16985  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
QEO92_03155  prs; ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
QEO92_12495  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
QEO92_04880  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
QEO92_02500  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
QEO92_05155  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
QEO92_09425  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
QEO92_09450  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
QEO92_09440  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
QEO92_05160  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
QEO92_16630  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
QEO92_16625  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
QEO92_09455  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
QEO92_22975  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
QEO92_09485  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
QEO92_23480  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
QEO92_08945  IMP cyclohydrolase [KO:K11176] [EC:3.5.4.10]
QEO92_12560  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
QEO92_16725  5'-nucleotidase C-terminal domain-containing protein [KO:K11751] [EC:3.1.3.5 3.6.1.45]
QEO92_08175  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
QEO92_25980  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
QEO92_12480  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
QEO92_20645  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
QEO92_02035  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
QEO92_05065  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
QEO92_00020  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
QEO92_07525  gpt; xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
QEO92_13085  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
QEO92_13090  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
QEO92_19610  molybdopterin-dependent oxidoreductase [KO:K13482] [EC:1.17.1.4]
QEO92_18010  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
QEO92_20190  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
QEO92_18015  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
QEO92_20185  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
QEO92_18020  (2Fe-2S)-binding protein [KO:K13483]
QEO92_20180  (2Fe-2S)-binding protein [KO:K13483]
QEO92_21455  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
QEO92_26550  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
QEO92_13130  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
QEO92_04985  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
QEO92_07520  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
QEO92_08120  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
QEO92_04690  HD family hydrolase [KO:K06952] [EC:3.1.3.89]
QEO92_04555  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
QEO92_02010  Ppx/GppA phosphatase family protein [KO:K01524] [EC:3.6.1.11 3.6.1.40]
QEO92_05180  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
QEO92_15675  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
QEO92_15715  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
QEO92_16005  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
QEO92_26005  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
QEO92_04435  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
QEO92_30510  adenine deaminase C-terminal domain-containing protein [KO:K01486] [EC:3.5.4.2]
QEO92_12920  ade; adenine deaminase [KO:K01486] [EC:3.5.4.2]
QEO92_17475  adenine deaminase C-terminal domain-containing protein [KO:K01486] [EC:3.5.4.2]
QEO92_07765  bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
QEO92_16445  YmdB family metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
QEO92_07345  adenylate kinase [KO:K00939] [EC:2.7.4.3]
QEO92_08870  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
QEO92_11795  metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
QEO92_27670  cysN; sulfate adenylyltransferase subunit CysN [KO:K00955] [EC:2.7.7.4 2.7.1.25]
QEO92_03265  cysN; sulfate adenylyltransferase subunit CysN [KO:K00956] [EC:2.7.7.4]
QEO92_03270  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
QEO92_27665  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
QEO92_06980  NAD(P)/FAD-dependent oxidoreductase [KO:K22879] [EC:1.14.13.113]
QEO92_07030  NAD(P)/FAD-dependent oxidoreductase [KO:K22879] [EC:1.14.13.113]
QEO92_13165  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
QEO92_28765  aspartate/glutamate racemase family protein [KO:K16841] [EC:5.1.99.3]
QEO92_24585  aspartate/glutamate racemase family protein [KO:K16841] [EC:5.1.99.3]
QEO92_12065  amidohydrolase family protein [KO:K01466] [EC:3.5.2.5]
QEO92_13205  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
QEO92_28055  polysaccharide deacetylase family protein [KO:K16842] [EC:3.5.2.5]
QEO92_13195  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
QEO92_13170  ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
QEO92_28060  ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
QEO92_15740  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
QEO92_15750  urease subunit beta [KO:K01429] [EC:3.5.1.5]
QEO92_15755  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
QEO92_18515  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
npm00030  Pentose phosphate pathway
npm00220  Arginine biosynthesis
npm00250  Alanine, aspartate and glutamate metabolism
npm00260  Glycine, serine and threonine metabolism
npm00340  Histidine metabolism
npm00630  Glyoxylate and dicarboxylate metabolism
npm00730  Thiamine metabolism
npm00740  Riboflavin metabolism
npm00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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