KEGG   PATHWAY: onl00240
Entry
onl00240                    Pathway                                
Name
Pyrimidine metabolism - Oreochromis niloticus (Nile tilapia)
Class
Metabolism; Nucleotide metabolism
Pathway map
onl00240  Pyrimidine metabolism
onl00240

Module
onl_M00046  Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate [PATH:onl00240]
onl_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP [PATH:onl00240]
onl_M00052  Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP [PATH:onl00240]
onl_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:onl00240]
onl_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP [PATH:onl00240]
Other DBs
GO: 0006220 0006213
Organism
Oreochromis niloticus (Nile tilapia) [GN:onl]
Gene
100689784  dpyd; dihydropyrimidine dehydrogenase [NADP(+)] isoform X1 [KO:K00207] [EC:1.3.1.2]
100690302  dctpp1; dCTP pyrophosphatase 1 [KO:K16904] [EC:3.6.1.12]
100690403  [KO:K00757] [EC:2.4.2.3]
100690751  [KO:K01937] [EC:6.3.4.2]
100691256  nudt2; bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] [KO:K01518] [EC:3.6.1.17]
100691324  [KO:K13421] [EC:2.4.2.10 4.1.1.23]
100691991  [KO:K01513] [EC:3.1.4.1 3.6.1.9]
100692091  asmtl; N-acetylserotonin O-methyltransferase-like protein [KO:K25435]
100693418  [KO:K01489] [EC:3.5.4.5]
100693789  [KO:K01081] [EC:3.1.3.5]
100694202  nt5m; 5'(3')-deoxyribonucleotidase, mitochondrial [KO:K01081] [EC:3.1.3.5]
100694899  dut; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X2 [KO:K01520] [EC:3.6.1.23]
100694900  [KO:K10807] [EC:1.17.4.1]
100695554  [KO:K13421] [EC:2.4.2.10 4.1.1.23]
100695989  [KO:K01511] [EC:3.6.1.6]
100696067  hddc2; HD domain-containing protein 2 [KO:K07023] [EC:3.1.3.89]
100696242  uckl1; uridine-cytidine kinase-like 1 isoform X4 [KO:K00876] [EC:2.7.1.48]
100696260  dtymk; thymidylate kinase [KO:K00943] [EC:2.7.4.9]
100696561  [KO:K10807] [EC:1.17.4.1]
100696772  [KO:K00940] [EC:2.7.4.6]
100696913  [KO:K19970] [EC:3.1.3.5]
100696922  nme3; nucleoside diphosphate kinase 3 isoform X1 [KO:K00940] [EC:2.7.4.6]
100697135  [KO:K00940] [EC:2.7.4.6]
100697351  nt5c3a; cytosolic 5'-nucleotidase 3A isoform X1 [KO:K24242]
100697655  [KO:K00876] [EC:2.7.1.48]
100698477  [KO:K01081] [EC:3.1.3.5]
100698595  [KO:K01081] [EC:3.1.3.5]
100698853  [KO:K10808] [EC:1.17.4.1]
100698935  [KO:K00876] [EC:2.7.1.48]
100699112  nme7; nucleoside diphosphate kinase 7 [KO:K00940] [EC:2.7.4.6]
100699134  [KO:K01489] [EC:3.5.4.5]
100699417  nt5c2; cytosolic purine 5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
100699570  [KO:K10808] [EC:1.17.4.1]
100699577  tymp; thymidine phosphorylase isoform X1 [KO:K00758] [EC:2.4.2.4]
100700233  cad; LOW QUALITY PROTEIN: CAD protein [KO:K11540] [EC:6.3.5.5 2.1.3.2 3.5.2.3]
100700310  tk1; thymidine kinase, cytosolic [KO:K00857] [EC:2.7.1.21]
100701537  nt5c3b; 7-methylguanosine phosphate-specific 5'-nucleotidase isoform X1 [KO:K24242]
100701747  cant1; soluble calcium-activated nucleotidase 1 isoform X2 [KO:K12304] [EC:3.6.1.6]
100701809  [KO:K24242]
100701937  uck1; uridine-cytidine kinase 1 [KO:K00876] [EC:2.7.1.48]
100702119  [KO:K01493] [EC:3.5.4.12]
100702443  [KO:K01081] [EC:3.1.3.5]
100702568  dpys; dihydropyrimidinase [KO:K01464] [EC:3.5.2.2]
100703020  [KO:K00940] [EC:2.7.4.6]
100703583  [KO:K00876] [EC:2.7.1.48]
100703671  cmpk1; UMP-CMP kinase [KO:K13800] [EC:2.7.4.14]
100703739  [KO:K00876] [EC:2.7.1.48]
100703902  ak9; adenylate kinase 9 isoform X3 [KO:K18533] [EC:2.7.4.3 2.7.4.6]
100704013  [KO:K01081] [EC:3.1.3.5]
100704242  entpd3; ectonucleoside triphosphate diphosphohydrolase 3 [KO:K01510] [EC:3.6.1.5]
100704298  entpd6; ectonucleoside triphosphate diphosphohydrolase 6 isoform X3 [KO:K01511] [EC:3.6.1.6]
100704637  [KO:K01511] [EC:3.6.1.6]
100705681  dhodh; dihydroorotate dehydrogenase (quinone), mitochondrial [KO:K00254] [EC:1.3.5.2]
100706399  dck; deoxycytidine kinase [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
100707381  entpd4; ectonucleoside triphosphate diphosphohydrolase 4 isoform X1 [KO:K12305] [EC:3.6.1.6]
100707523  [KO:K24242]
100707803  [KO:K16330] [EC:4.2.1.70 2.7.1.83]
100708084  upp2; uridine phosphorylase 2 [KO:K00757] [EC:2.4.2.3]
100708436  [KO:K01081] [EC:3.1.3.5]
100708787  [KO:K01937] [EC:6.3.4.2]
100709669  tyms; thymidylate synthase [KO:K00560] [EC:2.1.1.45]
100709923  [KO:K01513] [EC:3.1.4.1 3.6.1.9]
100709975  [KO:K19970] [EC:3.1.3.5]
100710041  [KO:K10808] [EC:1.17.4.1]
100710533  nme6; nucleoside diphosphate kinase 6 isoform X1 [KO:K00940] [EC:2.7.4.6]
100710536  [KO:K00893] [EC:2.7.1.74 2.7.1.76 2.7.1.113]
100710562  entpd1; ectonucleoside triphosphate diphosphohydrolase 1 isoform X1 [KO:K01510] [EC:3.6.1.5]
100711121  upb1; beta-ureidopropionase [KO:K01431] [EC:3.5.1.6]
100712150  tk2; thymidine kinase 2, mitochondrial isoform X1 [KO:K00857] [EC:2.7.1.21]
100712569  cmpk2; UMP-CMP kinase 2, mitochondrial [KO:K13809] [EC:2.7.4.14]
102076953  [KO:K13421] [EC:2.4.2.10 4.1.1.23]
102078803  [KO:K12304] [EC:3.6.1.6]
Compound
C00015  UDP
C00039  DNA
C00046  RNA
C00055  CMP
C00063  CTP
C00064  L-Glutamine
C00075  UTP
C00086  Urea
C00099  beta-Alanine
C00105  UMP
C00106  Uracil
C00112  CDP
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00169  Carbamoyl phosphate
C00178  Thymine
C00214  Thymidine
C00222  3-Oxopropanoate
C00239  dCMP
C00295  Orotate
C00299  Uridine
C00337  (S)-Dihydroorotate
C00363  dTDP
C00364  dTMP
C00365  dUMP
C00380  Cytosine
C00383  Malonate
C00429  5,6-Dihydrouracil
C00438  N-Carbamoyl-L-aspartate
C00458  dCTP
C00459  dTTP
C00460  dUTP
C00475  Cytidine
C00526  Deoxyuridine
C00672  2-Deoxy-D-ribose 1-phosphate
C00705  dCDP
C00813  Barbiturate
C00881  Deoxycytidine
C00941  3',5'-Cyclic CMP
C01013  3-Hydroxypropanoate
C01103  Orotidine 5'-phosphate
C01168  Pseudouridine 5'-phosphate
C01205  (R)-3-Amino-2-methylpropanoate
C01346  dUDP
C01368  3'-UMP
C01563  Carbamate
C02067  Pseudouridine
C02170  Methylmalonate
C02354  2',3'-Cyclic CMP
C02355  2',3'-Cyclic UMP
C02376  5-Methylcytosine
C02642  3-Ureidopropionate
C03997  5-Hydroxymethyldeoxycytidylate
C05281  5-Methylbarbiturate
C05822  3'-CMP
C06198  P1,P4-Bis(5'-uridyl) tetraphosphate
C11038  2'-Deoxy-5-hydroxymethylcytidine-5'-diphosphate
C11039  2'-Deoxy-5-hydroxymethylcytidine-5'-triphosphate
C15607  3-Oxo-3-ureidopropanoate
C20231  (Z)-3-Ureidoacrylate peracid
C20249  (Z)-3-Peroxyaminoacrylate
C20253  Aminoacrylate
C20254  Ureidoacrylate
C20846  3-Oxo-3-ureidoisobutyrate
C21028  (R)-5,6-Dihydrothymine
C21029  (R)-3-Ureidoisobutyrate
C22509  3',5'-Cyclic UMP
Related
pathway
onl00030  Pentose phosphate pathway
onl00220  Arginine biosynthesis
onl00250  Alanine, aspartate and glutamate metabolism
onl00280  Valine, leucine and isoleucine degradation
onl00410  beta-Alanine metabolism
KO pathway
ko00240   

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