KEGG   PATHWAY: ahf00270
Entry
ahf00270                    Pathway                                
Name
Cysteine and methionine metabolism - Arachis hypogaea (peanut)
Description
Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted from serine (via acetylserine) by transfer of hydrogen sulfide [MD:M00021]. In animals, methionine-derived homocysteine is used as sulfur source and its condensation product with serine (cystathionine) is converted to cysteine [MD:M00338]. Cysteine is metabolized to pyruvate in multiple routes. Methionine is an essential amino acid, which animals cannot synthesize. In bacteria and plants, methionine is synthesized from aspartate [MD:M00017]. S-Adenosylmethionine (SAM), synthesized from methionine and ATP, is a methyl group donor in many important transfer reactions including DNA methylation for regulation of gene expression. SAM may also be used to regenerate methionine in the methionine salvage pathway [MD:M00034].
Class
Metabolism; Amino acid metabolism
Pathway map
ahf00270  Cysteine and methionine metabolism
ahf00270

Module
ahf_M00021  Cysteine biosynthesis, serine => cysteine [PATH:ahf00270]
ahf_M00034  Methionine salvage pathway [PATH:ahf00270]
ahf_M00368  Ethylene biosynthesis, methionine => ethylene [PATH:ahf00270]
Other DBs
GO: 0006534 0006555
Organism
Arachis hypogaea (peanut) [GN:ahf]
Gene
112747142  serine acetyltransferase 1, chloroplastic-like [KO:K00640] [EC:2.3.1.30]
112747156  serine acetyltransferase 3, mitochondrial-like [KO:K00640] [EC:2.3.1.30]
112803828  serine acetyltransferase 5-like [KO:K00640] [EC:2.3.1.30]
112805374  serine acetyltransferase 2-like [KO:K00640] [EC:2.3.1.30]
112747663  serine acetyltransferase 2-like [KO:K00640] [EC:2.3.1.30]
112733586  serine acetyltransferase 5 [KO:K00640] [EC:2.3.1.30]
112790991  serine acetyltransferase 1, chloroplastic [KO:K00640] [EC:2.3.1.30]
112712947  serine acetyltransferase 1, chloroplastic-like [KO:K00640] [EC:2.3.1.30]
112735602  serine acetyltransferase 3, mitochondrial-like [KO:K00640] [EC:2.3.1.30]
112701835  serine acetyltransferase 1, chloroplastic [KO:K00640] [EC:2.3.1.30]
112720145  serine acetyltransferase 1, chloroplastic isoform X1 [KO:K00640] [EC:2.3.1.30]
112777784  serine acetyltransferase 3, mitochondrial-like [KO:K00640] [EC:2.3.1.30]
112756561  serine acetyltransferase 1, chloroplastic-like [KO:K00640] [EC:2.3.1.30]
112783424  serine acetyltransferase 4-like [KO:K00640] [EC:2.3.1.30]
112800272  serine acetyltransferase 2-like [KO:K00640] [EC:2.3.1.30]
112726440  serine acetyltransferase 5 [KO:K00640] [EC:2.3.1.30]
112764430  serine acetyltransferase 1, chloroplastic [KO:K00640] [EC:2.3.1.30]
112769583  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
112710946  cysteine synthase [KO:K01738] [EC:2.5.1.47]
112710947  cysteine synthase isoform X1 [KO:K01738] [EC:2.5.1.47]
112733601  cysteine synthase, chloroplastic/chromoplastic [KO:K01738] [EC:2.5.1.47]
112749873  cysteine synthase [KO:K01738] [EC:2.5.1.47]
112750179  cysteine synthase isoform X1 [KO:K01738] [EC:2.5.1.47]
112791562  cysteine synthase, chloroplastic/chromoplastic [KO:K01738] [EC:2.5.1.47]
112775834  cysteine synthase [KO:K01738] [EC:2.5.1.47]
112701829  cysteine synthase 2 [KO:K01738] [EC:2.5.1.47]
112721253  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
112800942  cysteine synthase isoform X1 [KO:K01738] [EC:2.5.1.47]
112801267  cysteine synthase [KO:K01738] [EC:2.5.1.47]
112727447  cysteine synthase [KO:K01738] [EC:2.5.1.47]
112764727  cysteine synthase 2 [KO:K01738] [EC:2.5.1.47]
112784599  uncharacterized protein LOC112784599 isoform X1 [KO:K01738] [EC:2.5.1.47]
112730543  bifunctional L-3-cyanoalanine synthase/cysteine synthase 1, mitochondrial [KO:K13034] [EC:2.5.1.47 4.4.1.9]
112797478  bifunctional L-3-cyanoalanine synthase/cysteine synthase 1, mitochondrial [KO:K13034] [EC:2.5.1.47 4.4.1.9]
112726280  bifunctional L-3-cyanoalanine synthase/cysteine synthase 1, mitochondrial [KO:K13034] [EC:2.5.1.47 4.4.1.9]
112744150  bifunctional L-3-cyanoalanine synthase/cysteine synthase 1, mitochondrial [KO:K13034] [EC:2.5.1.47 4.4.1.9]
112695955  cystathionine beta-lyase, chloroplastic isoform X1 [KO:K01760] [EC:4.4.1.13]
112756653  cystathionine beta-lyase, chloroplastic isoform X1 [KO:K01760] [EC:4.4.1.13]
112805600  uncharacterized protein LOC112805600 [KO:K00547] [EC:2.1.1.10]
112711770  homocysteine S-methyltransferase 3 [KO:K00547] [EC:2.1.1.10]
112772454  selenocysteine methyltransferase isoform X1 [KO:K00547] [EC:2.1.1.10]
112696236  selenocysteine methyltransferase [KO:K00547] [EC:2.1.1.10]
112775854  homocysteine S-methyltransferase 3 [KO:K00547] [EC:2.1.1.10]
112776347  homocysteine S-methyltransferase 3-like [KO:K00547] [EC:2.1.1.10]
112756338  selenocysteine methyltransferase isoform X1 [KO:K00547] [EC:2.1.1.10]
112721544  homocysteine S-methyltransferase 4 [KO:K00547] [EC:2.1.1.10]
112742725  homocysteine S-methyltransferase 4 [KO:K00547] [EC:2.1.1.10]
112696942  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1 [KO:K00549] [EC:2.1.1.14]
112754812  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 2 [KO:K00549] [EC:2.1.1.14]
112716846  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase [KO:K00549] [EC:2.1.1.14]
112783370  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase [KO:K00549] [EC:2.1.1.14]
112695610  S-adenosylmethionine synthase 1 [KO:K00789] [EC:2.5.1.6]
112695681  S-adenosylmethionine synthase 1 [KO:K00789] [EC:2.5.1.6]
112696025  S-adenosylmethionine synthase 3-like [KO:K00789] [EC:2.5.1.6]
112696036  S-adenosylmethionine synthase 3-like [KO:K00789] [EC:2.5.1.6]
112696054  S-adenosylmethionine synthase 3-like [KO:K00789] [EC:2.5.1.6]
112696568  S-adenosylmethionine synthase 3 [KO:K00789] [EC:2.5.1.6]
112754196  S-adenosylmethionine synthase 3 [KO:K00789] [EC:2.5.1.6]
112797165  S-adenosylmethionine synthase 3-like [KO:K00789] [EC:2.5.1.6]
112756986  S-adenosylmethionine synthase 1 [KO:K00789] [EC:2.5.1.6]
112758002  S-adenosylmethionine synthase 1 [KO:K00789] [EC:2.5.1.6]
112722671  S-adenosylmethionine synthase [KO:K00789] [EC:2.5.1.6]
112707447  S-adenosylmethionine synthase [KO:K00789] [EC:2.5.1.6]
112744690  S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
112750478  S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
112795815  S-adenosylmethionine decarboxylase proenzyme 4-like [KO:K01611] [EC:4.1.1.50]
112796005  S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
112719731  S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
112797982  S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
112705120  S-adenosylmethionine decarboxylase proenzyme 4 [KO:K01611] [EC:4.1.1.50]
112723012  S-adenosylmethionine decarboxylase proenzyme 4-like [KO:K01611] [EC:4.1.1.50]
112741120  S-adenosylmethionine decarboxylase proenzyme 4-like [KO:K01611] [EC:4.1.1.50]
112747154  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
112733933  spermidine synthase 2 [KO:K00797] [EC:2.5.1.16]
112750030  spermidine synthase [KO:K00797] [EC:2.5.1.16]
112791811  spermidine synthase 2 [KO:K00797] [EC:2.5.1.16]
112799836  spermidine synthase 2 [KO:K00797] [EC:2.5.1.16]
112705937  spermine synthase isoform X1 [KO:K00797] [EC:2.5.1.16]
112801105  spermidine synthase [KO:K00797] [EC:2.5.1.16]
112766201  spermine synthase [KO:K00797] [EC:2.5.1.16]
112768963  nicotianamine synthase [KO:K05953] [EC:2.5.1.43]
112710725  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
112695583  nicotianamine synthase [KO:K05953] [EC:2.5.1.43]
112703449  nicotianamine synthase [KO:K05953] [EC:2.5.1.43]
112779605  nicotianamine synthase [KO:K05953] [EC:2.5.1.43]
112758211  nicotianamine synthase [KO:K05953] [EC:2.5.1.43]
112705915  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1 [KO:K01244] [EC:3.2.2.16]
112764535  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1 [KO:K01244] [EC:3.2.2.16]
112711950  methylthioribose kinase isoform X1 [KO:K00899] [EC:2.7.1.100]
112711952  methylthioribose kinase [KO:K00899] [EC:2.7.1.100]
112776186  methylthioribose kinase [KO:K00899] [EC:2.7.1.100]
112776447  methylthioribose kinase isoform X2 [KO:K00899] [EC:2.7.1.100]
112800830  methylthioribose kinase isoform X1 [KO:K00899] [EC:2.7.1.100]
112726501  methylthioribose kinase [KO:K00899] [EC:2.7.1.100]
112766029  methylthioribose kinase 1-like isoform X1 [KO:K00899] [EC:2.7.1.100]
112771014  methylthioribose-1-phosphate isomerase [KO:K08963] [EC:5.3.1.23]
112757025  methylthioribose-1-phosphate isomerase-like [KO:K08963] [EC:5.3.1.23]
112707753  methylthioribose-1-phosphate isomerase [KO:K08963] [EC:5.3.1.23]
112770646  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
112707419  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
112729006  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
112711752  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2 [KO:K08967] [EC:1.13.11.53 1.13.11.54]
112711754  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 1 [KO:K08967] [EC:1.13.11.53 1.13.11.54]
112775449  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 1 [KO:K08967] [EC:1.13.11.53 1.13.11.54]
112776232  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2 [KO:K08967] [EC:1.13.11.53 1.13.11.54]
112761377  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
112706088  uncharacterized protein LOC112706088 [KO:K23977] [EC:2.6.1.117]
112764218  uncharacterized protein LOC112764218 [KO:K23977] [EC:2.6.1.117]
112789831  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
112790135  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
112771508  probable aminotransferase TAT2 isoform X1 [KO:K00815] [EC:2.6.1.5]
112772365  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
112737703  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
112737991  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
112707148  probable aminotransferase TAT2 isoform X1 [KO:K00815] [EC:2.6.1.5]
112707762  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
112709814  aromatic aminotransferase ISS1 [KO:K00837] [EC:2.6.1.-]
112777275  aromatic aminotransferase ISS1 isoform X1 [KO:K00837] [EC:2.6.1.-]
112775751  methionine gamma-lyase [KO:K01761] [EC:4.4.1.11]
112795594  methionine gamma-lyase [KO:K01761] [EC:4.4.1.11]
112740223  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
112747667  DNA (cytosine-5)-methyltransferase 1-like [KO:K00558] [EC:2.1.1.37]
112751272  DNA (cytosine-5)-methyltransferase CMT3 [KO:K00558] [EC:2.1.1.37]
112751621  DNA (cytosine-5)-methyltransferase 1 [KO:K00558] [EC:2.1.1.37]
112798058  DNA (cytosine-5)-methyltransferase CMT2 isoform X1 [KO:K00558] [EC:2.1.1.37]
112783544  DNA (cytosine-5)-methyltransferase CMT2 isoform X1 [KO:K00558] [EC:2.1.1.37]
112800277  DNA (cytosine-5)-methyltransferase 1-like [KO:K00558] [EC:2.1.1.37]
112801761  DNA (cytosine-5)-methyltransferase 1 [KO:K00558] [EC:2.1.1.37]
112802078  DNA (cytosine-5)-methyltransferase CMT3 [KO:K00558] [EC:2.1.1.37]
112695529  uncharacterized protein LOC112695529 [KO:K17398] [EC:2.1.1.37]
112758112  uncharacterized protein LOC112758112 [KO:K17398] [EC:2.1.1.37]
112792643  adenosylhomocysteinase [KO:K01251] [EC:3.13.2.1]
112795682  adenosylhomocysteinase [KO:K01251] [EC:3.13.2.1]
112736247  adenosylhomocysteinase [KO:K01251] [EC:3.13.2.1]
112740966  adenosylhomocysteinase [KO:K01251] [EC:3.13.2.1]
112732600  1-aminocyclopropane-1-carboxylate synthase [KO:K20772] [EC:4.4.1.14]
112732856  1-aminocyclopropane-1-carboxylate synthase [KO:K20772] [EC:4.4.1.14]
112790850  1-aminocyclopropane-1-carboxylate synthase [KO:K20772] [EC:4.4.1.14]
112797527  1-aminocyclopropane-1-carboxylate synthase 1 [KO:K20772] [EC:4.4.1.14]
112799681  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
112726355  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
112744203  1-aminocyclopropane-1-carboxylate synthase 1 [KO:K20772] [EC:4.4.1.14]
112732346  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
112748160  1-aminocyclopropane-1-carboxylate synthase 3-like [KO:K01762] [EC:4.4.1.14]
112790692  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
112751325  1-aminocyclopropane-1-carboxylate synthase 7 [KO:K01762] [EC:4.4.1.14]
112720599  1-aminocyclopropane-1-carboxylate synthase 3 [KO:K01762] [EC:4.4.1.14]
112705087  1-aminocyclopropane-1-carboxylate synthase 3-like [KO:K01762] [EC:4.4.1.14]
112800461  1-aminocyclopropane-1-carboxylate synthase 3 [KO:K01762] [EC:4.4.1.14]
112800765  1-aminocyclopropane-1-carboxylate synthase CMA101 [KO:K01762] [EC:4.4.1.14]
112764004  1-aminocyclopropane-1-carboxylate synthase 3-like [KO:K01762] [EC:4.4.1.14]
112802033  1-aminocyclopropane-1-carboxylate synthase 7 [KO:K01762] [EC:4.4.1.14]
112766489  1-aminocyclopropane-1-carboxylate oxidase [KO:K05933] [EC:1.14.17.4]
112766935  1-aminocyclopropane-1-carboxylate oxidase [KO:K05933] [EC:1.14.17.4]
112751340  1-aminocyclopropane-1-carboxylate oxidase 1 [KO:K05933] [EC:1.14.17.4]
112795960  1-aminocyclopropane-1-carboxylate oxidase [KO:K05933] [EC:1.14.17.4]
112702258  1-aminocyclopropane-1-carboxylate oxidase [KO:K05933] [EC:1.14.17.4]
112702261  1-aminocyclopropane-1-carboxylate oxidase [KO:K05933] [EC:1.14.17.4]
112702266  1-aminocyclopropane-1-carboxylate oxidase [KO:K05933] [EC:1.14.17.4]
112722852  1-aminocyclopropane-1-carboxylate oxidase [KO:K05933] [EC:1.14.17.4]
112706026  1-aminocyclopropane-1-carboxylate oxidase 5 [KO:K05933] [EC:1.14.17.4]
112706058  1-aminocyclopropane-1-carboxylate oxidase [KO:K05933] [EC:1.14.17.4]
112741262  1-aminocyclopropane-1-carboxylate oxidase [KO:K05933] [EC:1.14.17.4]
112762594  1-aminocyclopropane-1-carboxylate oxidase 5 [KO:K05933] [EC:1.14.17.4]
112764097  1-aminocyclopropane-1-carboxylate oxidase [KO:K05933] [EC:1.14.17.4]
112764645  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
112802019  1-aminocyclopropane-1-carboxylate oxidase 1 [KO:K05933] [EC:1.14.17.4]
112709028  aspartokinase 1, chloroplastic [KO:K00928] [EC:2.7.2.4]
112771097  aspartokinase 2, chloroplastic isoform X1 [KO:K00928] [EC:2.7.2.4]
112697116  aspartokinase 2, chloroplastic isoform X1 [KO:K00928] [EC:2.7.2.4]
112755014  aspartokinase 2, chloroplastic isoform X1 [KO:K00928] [EC:2.7.2.4]
112792634  bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic [KO:K12524] [EC:2.7.2.4 1.1.1.3]
112736252  bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic [KO:K12524] [EC:2.7.2.4 1.1.1.3]
112734205  uncharacterized protein LOC112734205 [KO:K00133] [EC:1.2.1.11]
112792044  uncharacterized protein LOC112792044 [KO:K00133] [EC:1.2.1.11]
112745395  homoserine kinase [KO:K00872] [EC:2.7.1.39]
112727606  homoserine kinase [KO:K00872] [EC:2.7.1.39]
112716416  cystathionine gamma-synthase 1, chloroplastic isoform X1 [KO:K27857] [EC:2.5.1.160]
112797810  cystathionine gamma-synthase 1, chloroplastic [KO:K27857] [EC:2.5.1.160]
112744507  cystathionine gamma-synthase 1, chloroplastic [KO:K27857] [EC:2.5.1.160]
112782319  cystathionine gamma-synthase 1, chloroplastic isoform X1 [KO:K27857] [EC:2.5.1.160]
112728658  branched-chain-amino-acid aminotransferase 6 isoform X1 [KO:K00826] [EC:2.6.1.42]
112728659  branched-chain-amino-acid aminotransferase 6 [KO:K00826] [EC:2.6.1.42]
112729468  branched-chain-amino-acid aminotransferase 6-like [KO:K00826] [EC:2.6.1.42]
112791346  putative branched-chain-amino-acid aminotransferase 7 [KO:K00826] [EC:2.6.1.42]
112791347  putative branched-chain-amino-acid aminotransferase 7 isoform X1 [KO:K00826] [EC:2.6.1.42]
112791348  branched-chain-amino-acid aminotransferase 6-like [KO:K00826] [EC:2.6.1.42]
112800455  branched-chain amino acid aminotransferase 2, chloroplastic isoform X1 [KO:K00826] [EC:2.6.1.42]
112706394  branched-chain-amino-acid aminotransferase 2, chloroplastic [KO:K00826] [EC:2.6.1.42]
112766219  branched-chain-amino-acid aminotransferase 2, chloroplastic [KO:K00826] [EC:2.6.1.42]
112733266  alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
112791240  alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
112751474  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial isoform X1 [KO:K00827] [EC:2.6.1.44 2.6.1.40]
112793367  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
112719918  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial isoform X1 [KO:K00827] [EC:2.6.1.44 2.6.1.40]
112797146  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
112728127  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
112743801  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
112732760  glutamate--cysteine ligase, chloroplastic [KO:K01919] [EC:6.3.2.2]
112790902  glutamate--cysteine ligase, chloroplastic isoform X1 [KO:K01919] [EC:6.3.2.2]
112696427  glutamate--cysteine ligase, chloroplastic isoform X1 [KO:K01919] [EC:6.3.2.2]
112754397  glutamate--cysteine ligase, chloroplastic isoform X1 [KO:K01919] [EC:6.3.2.2]
112763542  glutamate--cysteine ligase, chloroplastic [KO:K01919] [EC:6.3.2.2]
112695494  glutathione synthetase, chloroplastic [KO:K21456] [EC:6.3.2.3]
112758175  glutathione synthetase, chloroplastic [KO:K21456] [EC:6.3.2.3]
112716157  aspartate aminotransferase 1 [KO:K14454] [EC:2.6.1.1]
112783205  aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
112789911  aspartate aminotransferase, mitochondrial-like [KO:K14455] [EC:2.6.1.1]
112789912  aspartate aminotransferase, mitochondrial-like [KO:K14455] [EC:2.6.1.1]
112737780  aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
112697536  aspartate aminotransferase P2, mitochondrial [KO:K00811] [EC:2.6.1.1]
112755759  aspartate aminotransferase P2, mitochondrial [KO:K00811] [EC:2.6.1.1]
112771170  thiosulfate/3-mercaptopyruvate sulfurtransferase 2 isoform X1 [KO:K01011] [EC:2.8.1.1 2.8.1.2]
112703388  thiosulfate/3-mercaptopyruvate sulfurtransferase 2 isoform X1 [KO:K01011] [EC:2.8.1.1 2.8.1.2]
112802888  L-lactate dehydrogenase A [KO:K00016] [EC:1.1.1.27]
112749602  L-lactate dehydrogenase B-like [KO:K00016] [EC:1.1.1.27]
112720825  L-lactate dehydrogenase A [KO:K00016] [EC:1.1.1.27]
112801526  L-lactate dehydrogenase B-like [KO:K00016] [EC:1.1.1.27]
112715109  D-cysteine desulfhydrase 2, mitochondrial isoform X1 [KO:K05396] [EC:4.4.1.15]
112784032  D-cysteine desulfhydrase 2, mitochondrial isoform X1 [KO:K05396] [EC:4.4.1.15]
112727441  bifunctional D-cysteine desulfhydrase/1-aminocyclopropane-1-carboxylate deaminase, mitochondrial [KO:K05396] [EC:4.4.1.15]
112743949  bifunctional D-cysteine desulfhydrase/1-aminocyclopropane-1-carboxylate deaminase, mitochondrial [KO:K05396] [EC:4.4.1.15]
112710614  L-cysteine desulfhydrase-like [KO:K22207] [EC:4.4.1.28]
112710680  probable L-cysteine desulfhydrase, chloroplastic [KO:K22207] [EC:4.4.1.28]
112695619  probable L-cysteine desulfhydrase, chloroplastic [KO:K22207] [EC:4.4.1.28]
112775364  L-cysteine desulfhydrase [KO:K22207] [EC:4.4.1.28]
112775746  probable L-cysteine desulfhydrase, chloroplastic [KO:K22207] [EC:4.4.1.28]
112757987  probable L-cysteine desulfhydrase, chloroplastic [KO:K22207] [EC:4.4.1.28]
112711210  malate dehydrogenase, cytoplasmic [KO:K00025] [EC:1.1.1.37]
112711212  malate dehydrogenase [KO:K00025] [EC:1.1.1.37]
112735613  malate dehydrogenase, cytoplasmic isoform X1 [KO:K00025] [EC:1.1.1.37]
112776382  malate dehydrogenase, cytoplasmic [KO:K00025] [EC:1.1.1.37]
112776383  malate dehydrogenase [KO:K00025] [EC:1.1.1.37]
112726743  malate dehydrogenase, cytoplasmic isoform X1 [KO:K00025] [EC:1.1.1.37]
112728667  malate dehydrogenase 2, peroxisomal [KO:K00026] [EC:1.1.1.37]
112710233  malate dehydrogenase, chloroplastic [KO:K00026] [EC:1.1.1.37]
112748103  malate dehydrogenase, glyoxysomal-like [KO:K00026] [EC:1.1.1.37]
112790043  malate dehydrogenase, mitochondrial [KO:K00026] [EC:1.1.1.37]
112791339  malate dehydrogenase 2, peroxisomal [KO:K00026] [EC:1.1.1.37]
112718423  malate dehydrogenase, chloroplastic [KO:K00026] [EC:1.1.1.37]
112737907  malate dehydrogenase, mitochondrial [KO:K00026] [EC:1.1.1.37]
112722502  malate dehydrogenase, chloroplastic [KO:K00026] [EC:1.1.1.37]
112800443  malate dehydrogenase, glyoxysomal-like [KO:K00026] [EC:1.1.1.37]
112696861  S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent), chloroplastic isoform X1 [KO:K22846] [EC:2.5.1.144]
112754722  S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent), chloroplastic isoform X1 [KO:K22846] [EC:2.5.1.144]
112711965  D-3-phosphoglycerate dehydrogenase 1, chloroplastic [KO:K00058] [EC:1.1.1.95 1.1.1.399]
112773142  D-3-phosphoglycerate dehydrogenase 2, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
112775052  D-3-phosphoglycerate dehydrogenase 1, chloroplastic [KO:K00058] [EC:1.1.1.95 1.1.1.399]
112795532  D-3-phosphoglycerate dehydrogenase 2, chloroplastic [KO:K00058] [EC:1.1.1.95 1.1.1.399]
112703824  D-3-phosphoglycerate dehydrogenase 2, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
112740807  D-3-phosphoglycerate dehydrogenase 2, chloroplastic [KO:K00058] [EC:1.1.1.95 1.1.1.399]
112747661  phosphoserine aminotransferase 2, chloroplastic-like [KO:K00831] [EC:2.6.1.52]
112800271  phosphoserine aminotransferase 2, chloroplastic-like [KO:K00831] [EC:2.6.1.52]
Compound
C00019  S-Adenosyl-L-methionine
C00021  S-Adenosyl-L-homocysteine
C00022  Pyruvate
C00041  L-Alanine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00065  L-Serine
C00073  L-Methionine
C00094  Sulfite
C00097  L-Cysteine
C00109  2-Oxobutanoate
C00155  L-Homocysteine
C00170  5'-Methylthioadenosine
C00197  3-Phospho-D-glycerate
C00263  L-Homoserine
C00283  Hydrogen sulfide
C00409  Methanethiol
C00441  L-Aspartate 4-semialdehyde
C00491  L-Cystine
C00506  L-Cysteate
C00606  3-Sulfino-L-alanine
C00793  D-Cysteine
C00957  Mercaptopyruvate
C00979  O-Acetyl-L-serine
C01005  O-Phospho-L-serine
C01077  O-Acetyl-L-homoserine
C01102  O-Phospho-L-homoserine
C01118  O-Succinyl-L-homoserine
C01137  S-Adenosylmethioninamine
C01180  4-Methylthio-2-oxobutanoic acid
C01234  1-Aminocyclopropane-1-carboxylate
C01817  L-Homocystine
C01962  Thiocysteine
C02218  Dehydroalanine
C02291  L-Cystathionine
C02356  (S)-2-Aminobutanoate
C02989  L-Methionine S-oxide
C03082  4-Phospho-L-aspartate
C03089  5-Methylthio-D-ribose
C03145  N-Formylmethionine
C03232  3-Phosphonooxypyruvate
C03431  S-Inosyl-L-homocysteine
C03539  S-Ribosyl-L-homocysteine
C04188  S-Methyl-5-thio-D-ribose 1-phosphate
C04582  S-Methyl-5-thio-D-ribulose 1-phosphate
C05324  Nicotianamine
C05524  Aminoacyl-L-methionine
C05526  S-Glutathionyl-L-cysteine
C05527  3-Sulfinylpyruvate
C05528  3-Sulfopyruvate
C05823  3-Mercaptolactate
C05824  S-Sulfo-L-cysteine
C06547  Ethylene
C08276  3-(Methylthio)propanoate
C09306  Sulfur dioxide
C11437  1-Deoxy-D-xylulose 5-phosphate
C11481  HSO3-
C11499  (S)-3-Sulfolactate
C11537  (2R)-3-Sulfolactate
C15606  1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one
C15650  2,3-Diketo-5-methylthiopentyl-1-phosphate
C15651  2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate
C18049  N-Acyl-L-homoserine lactone
C19787  5'-S-Methyl-5'-thioinosine
C21015  gamma-L-Glutamyl-L-2-aminobutyrate
C21016  Ophthalmate
C22359  S-Methyl-1-thio-D-xylulose 5-phosphate
Reference
  Authors
Sekowska A, Denervaud V, Ashida H, Michoud K, Haas D, Yokota A, Danchin A
  Title
Bacterial variations on the methionine salvage pathway.
  Journal
BMC Microbiol 4:9 (2004)
DOI:10.1186/1471-2180-4-9
Reference
  Authors
Ashida H, Saito Y, Kojima C, Kobayashi K, Ogasawara N, Yokota A.
  Title
A functional link between RuBisCO-like protein of Bacillus and photosynthetic RuBisCO.
  Journal
Science 302:286-90 (2003)
DOI:10.1126/science.1086997
Reference
  Authors
Sekowska A, Danchin A.
  Title
The methionine salvage pathway in Bacillus subtilis.
  Journal
BMC Microbiol 2:8 (2002)
DOI:10.1186/1471-2180-2-8
Reference
  Authors
Berger BJ, English S, Chan G, Knodel MH.
  Title
Methionine regeneration and aminotransferases in Bacillus subtilis, Bacillus cereus, and Bacillus anthracis.
  Journal
J Bacteriol 185:2418-31 (2003)
DOI:10.1128/JB.185.8.2418-2431.2003
Reference
  Authors
Goyer A, Collakova E, Shachar-Hill Y, Hanson AD
  Title
Functional characterization of a methionine gamma-lyase in Arabidopsis and its implication in an alternative to the reverse trans-sulfuration pathway.
  Journal
Plant Cell Physiol 48:232-42 (2007)
DOI:10.1093/pcp/pcl055
Reference
  Authors
Rebeille F, Jabrin S, Bligny R, Loizeau K, Gambonnet B, Van Wilder V, Douce R, Ravanel S
  Title
Methionine catabolism in Arabidopsis cells is initiated by a gamma-cleavage process and leads to S-methylcysteine and isoleucine syntheses.
  Journal
Proc Natl Acad Sci U S A 103:15687-92 (2006)
DOI:10.1073/pnas.0606195103
Reference
  Authors
Pirkov I, Norbeck J, Gustafsson L, Albers E
  Title
A complete inventory of all enzymes in the eukaryotic methionine salvage pathway.
  Journal
FEBS J 275:4111-20 (2008)
DOI:10.1111/j.1742-4658.2008.06552.x
Reference
  Authors
Ashida H, Saito Y, Kojima C, Yokota A
  Title
Enzymatic characterization of 5-methylthioribulose-1-phosphate dehydratase of the methionine salvage pathway in Bacillus subtilis.
  Journal
Biosci Biotechnol Biochem 72:959-67 (2008)
DOI:10.1271/bbb.70651
Reference
  Authors
Kitabatake M, So MW, Tumbula DL, Soll D
  Title
Cysteine biosynthesis pathway in the archaeon Methanosarcina barkeri encoded by acquired bacterial genes?
  Journal
J Bacteriol 182:143-5 (2000)
DOI:10.1128/JB.182.1.143-145.2000
Reference
  Authors
Mino K, Ishikawa K
  Title
Characterization of a novel thermostable O-acetylserine sulfhydrylase from Aeropyrum pernix K1.
  Journal
J Bacteriol 185:2277-84 (2003)
DOI:10.1128/JB.185.7.2277-2284.2003
Reference
  Authors
Tanabe S
  Title
Development of assay methods for endogenous inorganic sulfur compounds and sulfurtransferases and evaluation of the physiological functions of bound sulfur.
  Journal
Yakugaku Zasshi 128:881-900 (2008)
DOI:10.1248/yakushi.128.881
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
  Authors
Gutierrez JA, Crowder T, Rinaldo-Matthis A, Ho MC, Almo SC, Schramm VL
  Title
Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing.
  Journal
Nat Chem Biol 5:251-7 (2009)
DOI:10.1038/nchembio.153
Related
pathway
ahf00010  Glycolysis / Gluconeogenesis
ahf00250  Alanine, aspartate and glutamate metabolism
ahf00260  Glycine, serine and threonine metabolism
ahf00290  Valine, leucine and isoleucine biosynthesis
ahf00430  Taurine and hypotaurine metabolism
ahf00480  Glutathione metabolism
ahf00620  Pyruvate metabolism
ahf00640  Propanoate metabolism
ahf00770  Pantothenate and CoA biosynthesis
ahf00900  Terpenoid backbone biosynthesis
ahf00920  Sulfur metabolism
KO pathway
ko00270   
LinkDB

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