KEGG   PATHWAY: cmax00230
Entry
cmax00230                   Pathway                                
Name
Purine metabolism - Cucurbita maxima (winter squash)
Class
Metabolism; Nucleotide metabolism
Pathway map
cmax00230  Purine metabolism
cmax00230

Module
cmax_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:cmax00230]
cmax_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:cmax00230]
cmax_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:cmax00230]
cmax_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:cmax00230]
cmax_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:cmax00230]
Other DBs
GO: 0006163 0042278
Organism
Cucurbita maxima (winter squash) [GN:cmax]
Gene
111490346  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase-like [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
111495463  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase-like [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
111468256  nudix hydrolase 7-like isoform X1 [KO:K26956] [EC:3.6.1.13 3.6.1.22]
111477931  nudix hydrolase 10-like [KO:K26956] [EC:3.6.1.13 3.6.1.22]
111486492  nudix hydrolase 7-like isoform X1 [KO:K26956] [EC:3.6.1.13 3.6.1.22]
111481706  nudix hydrolase 23, chloroplastic [KO:K18453] [EC:3.6.1.13 3.6.1.18]
111468947  nudix hydrolase 14, chloroplastic [KO:K18447] [EC:3.6.1.21]
111468945  phosphoglucomutase, chloroplastic-like [KO:K01835] [EC:5.4.2.2]
111487591  LOW QUALITY PROTEIN: phosphoglucomutase, cytoplasmic-like [KO:K01835] [EC:5.4.2.2]
111472098  phosphoglucomutase, cytoplasmic [KO:K01835] [EC:5.4.2.2]
111490889  phosphoglucomutase, chloroplastic-like [KO:K01835] [EC:5.4.2.2]
111465041  ribose-phosphate pyrophosphokinase 1-like [KO:K00948] [EC:2.7.6.1]
111470638  ribose-phosphate pyrophosphokinase 1 isoform X1 [KO:K00948] [EC:2.7.6.1]
111491511  ribose-phosphate pyrophosphokinase 1-like [KO:K00948] [EC:2.7.6.1]
111498414  ribose-phosphate pyrophosphokinase 1-like [KO:K00948] [EC:2.7.6.1]
111484214  amidophosphoribosyltransferase, chloroplastic-like [KO:K00764] [EC:2.4.2.14]
111499617  amidophosphoribosyltransferase, chloroplastic-like [KO:K00764] [EC:2.4.2.14]
111483025  phosphoribosylamine--glycine ligase-like [KO:K01945] [EC:6.3.4.13]
111484875  phosphoribosylamine--glycine ligase-like [KO:K01945] [EC:6.3.4.13]
111488685  phosphoribosylglycinamide formyltransferase, chloroplastic [KO:K00601] [EC:2.1.2.2]
111477214  probable phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial [KO:K01952] [EC:6.3.5.3]
111490471  probable phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial [KO:K01952] [EC:6.3.5.3]
111476680  phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic/mitochondrial [KO:K01933] [EC:6.3.3.1]
111487615  phosphoribosylaminoimidazole carboxylase, chloroplastic-like isoform X1 [KO:K11808] [EC:4.1.1.21]
111489012  phosphoribosylaminoimidazole carboxylase, chloroplastic-like isoform X1 [KO:K11808] [EC:4.1.1.21]
111492147  phosphoribosylaminoimidazole-succinocarboxamide synthase, chloroplastic [KO:K01923] [EC:6.3.2.6]
111478258  uncharacterized protein LOC111478258 [KO:K01756] [EC:4.3.2.2]
111490986  uncharacterized protein LOC111490986 [KO:K01756] [EC:4.3.2.2]
111490103  uncharacterized protein LOC111490103 [KO:K00602] [EC:2.1.2.3 3.5.4.10]
111495272  uncharacterized protein LOC111495272 isoform X1 [KO:K00602] [EC:2.1.2.3 3.5.4.10]
111496082  adenine phosphoribosyltransferase 1-like [KO:K00759] [EC:2.4.2.7]
111492000  adenine phosphoribosyltransferase 1, chloroplastic isoform X1 [KO:K00759] [EC:2.4.2.7]
111469144  adenine phosphoribosyltransferase 3-like isoform X1 [KO:K00759] [EC:2.4.2.7]
111465123  adenine phosphoribosyltransferase 3-like [KO:K00759] [EC:2.4.2.7]
111491812  adenine phosphoribosyltransferase 5-like [KO:K00759] [EC:2.4.2.7]
111498514  adenine phosphoribosyltransferase 3-like [KO:K00759] [EC:2.4.2.7]
111496329  adenine phosphoribosyltransferase 5-like [KO:K00759] [EC:2.4.2.7]
111479092  uncharacterized protein LOC111479092 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
111492732  uncharacterized protein LOC111492732 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
111479950  uncharacterized protein LOC111479950 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
111472327  uncharacterized protein LOC111472327 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
111487323  uncharacterized protein LOC111487323 [KO:K00760] [EC:2.4.2.8]
111468080  inosine-5'-monophosphate dehydrogenase 2 [KO:K00088] [EC:1.1.1.205]
111489986  uncharacterized protein LOC111489986 [KO:K00940] [EC:2.7.4.6]
111472907  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
111495146  uncharacterized protein LOC111495146 [KO:K00940] [EC:2.7.4.6]
111481322  nucleoside diphosphate kinase 3-like [KO:K00940] [EC:2.7.4.6]
111471351  probable apyrase 6 isoform X1 [KO:K01510] [EC:3.6.1.5]
111493176  probable apyrase 6 [KO:K01510] [EC:3.6.1.5]
111466003  apyrase 2-like isoform X1 [KO:K14641] [EC:3.6.1.5]
111476496  apyrase 2-like [KO:K14641] [EC:3.6.1.5]
111478226  apyrase 2-like [KO:K14641] [EC:3.6.1.5]
111479791  inosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
111485375  xanthine dehydrogenase 1-like isoform X1 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
111488683  nudix hydrolase 25 [KO:K26955] [EC:3.6.1.17]
111491012  uncharacterized protein LOC111491012 [KO:K01951] [EC:6.3.5.2]
111472329  guanylate kinase 3, chloroplastic-like isoform X1 [KO:K00942] [EC:2.7.4.8]
111466032  guanylate kinase 2-like [KO:K00942] [EC:2.7.4.8]
111467216  guanylate kinase 2-like [KO:K00942] [EC:2.7.4.8]
111479039  guanylate kinase 3, chloroplastic [KO:K00942] [EC:2.7.4.8]
111478750  ribonucleoside-diphosphate reductase large subunit-like [KO:K10807] [EC:1.17.4.1]
111496788  ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
111489238  ribonucleoside-diphosphate reductase small chain-like [KO:K10808] [EC:1.17.4.1]
111482520  ribonucleoside-diphosphate reductase small chain [KO:K10808] [EC:1.17.4.1]
111468637  HD domain-containing protein 2-like [KO:K07023] [EC:3.1.3.89]
111487961  HD domain-containing protein C4G3.17-like [KO:K07023] [EC:3.1.3.89]
111494015  HD domain-containing protein 2-like isoform X1 [KO:K07023] [EC:3.1.3.89]
111468905  HD domain-containing protein C4G3.17 [KO:K07023] [EC:3.1.3.89]
111497113  exopolyphosphatase PRUNE1-like [KO:K01514] [EC:3.6.1.11]
111479357  probable GTP diphosphokinase CRSH, chloroplastic [KO:K00951] [EC:2.7.6.5]
111482468  putative GTP diphosphokinase RSH1, chloroplastic isoform X1 [KO:K00951] [EC:2.7.6.5]
111494380  probable GTP diphosphokinase RSH2, chloroplastic [KO:K00951] [EC:2.7.6.5]
111488570  probable GTP diphosphokinase RSH2, chloroplastic [KO:K00951] [EC:2.7.6.5]
111479883  probable GTP diphosphokinase RSH3, chloroplastic [KO:K00951] [EC:2.7.6.5]
111492725  probable GTP diphosphokinase RSH2, chloroplastic [KO:K00951] [EC:2.7.6.5]
111492821  putative GTP diphosphokinase RSH1, chloroplastic isoform X1 [KO:K00951] [EC:2.7.6.5]
111486697  phytosulfokine receptor 1 [KO:K27625] [EC:2.7.11.1 4.6.1.2]
111488483  phytosulfokine receptor 1-like [KO:K27625] [EC:2.7.11.1 4.6.1.2]
111465996  adenylosuccinate synthetase, chloroplastic-like [KO:K01939] [EC:6.3.4.4]
111467197  adenylosuccinate synthetase, chloroplastic [KO:K01939] [EC:6.3.4.4]
111478175  AMP deaminase [KO:K01490] [EC:3.5.4.6]
111466243  AMP deaminase-like [KO:K01490] [EC:3.5.4.6]
111498669  adenosine kinase 2-like [KO:K00856] [EC:2.7.1.20]
111488880  adenosine kinase 2-like [KO:K00856] [EC:2.7.1.20]
111490228  adenylate kinase 4 [KO:K00939] [EC:2.7.4.3]
111481491  probable adenylate kinase 7, mitochondrial [KO:K00939] [EC:2.7.4.3]
111471193  adenylate kinase 1, chloroplastic-like [KO:K00939] [EC:2.7.4.3]
111485087  adenylate kinase 4-like [KO:K00939] [EC:2.7.4.3]
111487004  probable adenylate kinase 6, chloroplastic isoform X1 [KO:K00939] [EC:2.7.4.3]
111487285  adenylate kinase, chloroplastic-like isoform X1 [KO:K00939] [EC:2.7.4.3]
111486703  probable adenylate kinase 7, mitochondrial [KO:K00939] [EC:2.7.4.3]
111488943  adenylate kinase, chloroplastic [KO:K00939] [EC:2.7.4.3]
111465483  adenylate kinase 5, chloroplastic isoform X1 [KO:K00939] [EC:2.7.4.3]
111477697  adenylate kinase-like [KO:K00939] [EC:2.7.4.3]
111499909  adenylate kinase isoenzyme 6 homolog [KO:K18532] [EC:2.7.4.3]
111483633  adenylate kinase isoenzyme 6 homolog isoform X1 [KO:K18532] [EC:2.7.4.3]
111470238  cancer-related nucleoside-triphosphatase homolog isoform X1 [KO:K06928] [EC:3.6.1.15]
111493831  ectonucleotide pyrophosphatase/phosphodiesterase family member 1-like [KO:K01513] [EC:3.1.4.1 3.6.1.9]
111465258  bifunctional bis(5'-adenosyl)-triphosphatase/adenylylsulfatase FHIT [KO:K01522] [EC:3.6.1.29]
111498527  bifunctional bis(5'-adenosyl)-triphosphatase/adenylylsulfatase FHIT-like [KO:K01522] [EC:3.6.1.29]
111479239  ATP sulfurylase 1, chloroplastic-like [KO:K13811] [EC:2.7.7.4 2.7.1.25]
111480215  ATP sulfurylase 2 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
111499372  ATP sulfurylase 1, chloroplastic-like [KO:K13811] [EC:2.7.7.4 2.7.1.25]
111472843  adenylyl-sulfate kinase 3-like [KO:K00860] [EC:2.7.1.25]
111482821  adenylyl-sulfate kinase 3-like [KO:K00860] [EC:2.7.1.25]
111497257  adenylyl-sulfate kinase 3-like isoform X1 [KO:K00860] [EC:2.7.1.25]
111483165  adenylyl-sulfate kinase 3-like [KO:K00860] [EC:2.7.1.25]
111467578  uricase-2-like [KO:K00365] [EC:1.7.3.3]
111482298  uricase-2 isozyme 2-like [KO:K00365] [EC:1.7.3.3]
111475233  uric acid degradation bifunctional protein TTL [KO:K13484] [EC:3.5.2.17 4.1.1.97]
111473810  uric acid degradation bifunctional protein TTL-like [KO:K13484] [EC:3.5.2.17 4.1.1.97]
111490122  allantoinase [KO:K01466] [EC:3.5.2.5]
111490121  allantoate deiminase 2-like [KO:K02083] [EC:3.5.3.9]
111495274  allantoate deiminase 1 isoform X1 [KO:K02083] [EC:3.5.3.9]
111498454  (S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
111474417  ureidoglycolate hydrolase [KO:K18151] [EC:3.5.1.116]
111492303  urease [KO:K01427] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
cmax00030  Pentose phosphate pathway
cmax00220  Arginine biosynthesis
cmax00250  Alanine, aspartate and glutamate metabolism
cmax00260  Glycine, serine and threonine metabolism
cmax00340  Histidine metabolism
cmax00630  Glyoxylate and dicarboxylate metabolism
cmax00730  Thiamine metabolism
cmax00740  Riboflavin metabolism
cmax00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

DBGET integrated database retrieval system