KEGG   PATHWAY: cmax00270
Entry
cmax00270                   Pathway                                
Name
Cysteine and methionine metabolism - Cucurbita maxima (winter squash)
Description
Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted from serine (via acetylserine) by transfer of hydrogen sulfide [MD:M00021]. In animals, methionine-derived homocysteine is used as sulfur source and its condensation product with serine (cystathionine) is converted to cysteine [MD:M00338]. Cysteine is metabolized to pyruvate in multiple routes. Methionine is an essential amino acid, which animals cannot synthesize. In bacteria and plants, methionine is synthesized from aspartate [MD:M00017]. S-Adenosylmethionine (SAM), synthesized from methionine and ATP, is a methyl group donor in many important transfer reactions including DNA methylation for regulation of gene expression. SAM may also be used to regenerate methionine in the methionine salvage pathway [MD:M00034].
Class
Metabolism; Amino acid metabolism
Pathway map
cmax00270  Cysteine and methionine metabolism
cmax00270

Module
cmax_M00021  Cysteine biosynthesis, serine => cysteine [PATH:cmax00270]
cmax_M00034  Methionine salvage pathway [PATH:cmax00270]
cmax_M00368  Ethylene biosynthesis, methionine => ethylene [PATH:cmax00270]
Other DBs
GO: 0006534 0006555
Organism
Cucurbita maxima (winter squash) [GN:cmax]
Gene
111480608  serine acetyltransferase 1, chloroplastic-like [KO:K00640] [EC:2.3.1.30]
111474114  serine acetyltransferase 1, chloroplastic-like [KO:K00640] [EC:2.3.1.30]
111465397  serine acetyltransferase 5 [KO:K00640] [EC:2.3.1.30]
111497355  serine acetyltransferase 2-like [KO:K00640] [EC:2.3.1.30]
111493685  cysteine synthase [KO:K01738] [EC:2.5.1.47]
111495347  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
111495355  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
111466399  cysteine synthase, chloroplastic/chromoplastic-like isoform X1 [KO:K01738] [EC:2.5.1.47]
111465603  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
111492818  cysteine synthase, chloroplastic/chromoplastic [KO:K01738] [EC:2.5.1.47]
111473555  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
111473556  cysteine synthase-like isoform X1 [KO:K01738] [EC:2.5.1.47]
111476428  cysteine synthase 2 [KO:K01738] [EC:2.5.1.47]
111499275  bifunctional L-3-cyanoalanine synthase/cysteine synthase 1, mitochondrial [KO:K13034] [EC:2.5.1.47 4.4.1.9]
111466006  cystathionine beta-lyase, chloroplastic isoform X1 [KO:K01760] [EC:4.4.1.13]
111488001  homocysteine S-methyltransferase 2-like [KO:K00547] [EC:2.1.1.10]
111467714  homocysteine S-methyltransferase 1-like [KO:K00547] [EC:2.1.1.10]
111494830  homocysteine S-methyltransferase 3-like [KO:K00547] [EC:2.1.1.10]
111499379  homocysteine S-methyltransferase 3-like [KO:K00547] [EC:2.1.1.10]
111487630  homocysteine S-methyltransferase 1-like [KO:K00547] [EC:2.1.1.10]
111474318  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase-like [KO:K00549] [EC:2.1.1.14]
111482249  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase [KO:K00549] [EC:2.1.1.14]
111473439  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase-like [KO:K00549] [EC:2.1.1.14]
111473442  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase-like [KO:K00549] [EC:2.1.1.14]
111479880  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase-like [KO:K00549] [EC:2.1.1.14]
111485391  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1-like [KO:K00549] [EC:2.1.1.14]
111497829  S-adenosylmethionine synthase 1-like [KO:K00789] [EC:2.5.1.6]
111481528  S-adenosylmethionine synthase 2-like [KO:K00789] [EC:2.5.1.6]
111488251  S-adenosylmethionine synthase 1 [KO:K00789] [EC:2.5.1.6]
111477898  S-adenosylmethionine synthase 3 [KO:K00789] [EC:2.5.1.6]
111493080  S-adenosylmethionine synthase 2-like [KO:K00789] [EC:2.5.1.6]
111468605  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
111479298  S-adenosylmethionine decarboxylase proenzyme 4-like [KO:K01611] [EC:4.1.1.50]
111493976  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
111481497  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
111499056  S-adenosylmethionine decarboxylase proenzyme 4 [KO:K01611] [EC:4.1.1.50]
111492585  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
111494461  S-adenosylmethionine decarboxylase proenzyme 4-like [KO:K01611] [EC:4.1.1.50]
111467782  spermine synthase-like [KO:K00797] [EC:2.5.1.16]
111495031  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
111466453  spermidine synthase-like [KO:K00797] [EC:2.5.1.16]
111491249  spermine synthase-like isoform X1 [KO:K00797] [EC:2.5.1.16]
111485649  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
111497722  spermidine synthase [KO:K00797] [EC:2.5.1.16]
111493502  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
111465632  nicotianamine synthase [KO:K05953] [EC:2.5.1.43]
111486493  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
111485338  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
111486247  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1-like [KO:K01244] [EC:3.2.2.16]
111468484  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 2-like [KO:K01244] [EC:3.2.2.16]
111482834  methylthioribose kinase [KO:K00899] [EC:2.7.1.100]
111467061  methylthioribose-1-phosphate isomerase [KO:K08963] [EC:5.3.1.23]
111482722  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
111480956  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
111480080  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
111473097  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
111499393  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 4-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
111476876  uncharacterized protein LOC111476876 isoform X1 [KO:K23977] [EC:2.6.1.117]
111469691  tyrosine aminotransferase-like [KO:K00815] [EC:2.6.1.5]
111469693  tyrosine aminotransferase-like [KO:K00815] [EC:2.6.1.5]
111469736  tyrosine aminotransferase-like [KO:K00815] [EC:2.6.1.5]
111469919  tyrosine aminotransferase-like isoform X1 [KO:K00815] [EC:2.6.1.5]
111480434  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
111488646  aromatic aminotransferase ISS1 [KO:K00837] [EC:2.6.1.-]
111465256  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
111498738  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
111469051  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
111489794  DNA (cytosine-5)-methyltransferase 1B-like isoform X1 [KO:K00558] [EC:2.1.1.37]
111498655  putative DNA (cytosine-5)-methyltransferase CMT1 isoform X1 [KO:K00558] [EC:2.1.1.37]
111485397  DNA (cytosine-5)-methyltransferase CMT3-like isoform X1 [KO:K00558] [EC:2.1.1.37]
111466330  DNA (cytosine-5)-methyltransferase CMT3 [KO:K00558] [EC:2.1.1.37]
111493532  uncharacterized protein LOC111493532 [KO:K17398] [EC:2.1.1.37]
111473468  adenosylhomocysteinase-like [KO:K01251] [EC:3.13.2.1]
111499104  adenosylhomocysteinase [KO:K01251] [EC:3.13.2.1]
111499253  1-aminocyclopropane-1-carboxylate synthase CMW33 [KO:K20772] [EC:4.4.1.14]
111499264  1-aminocyclopropane-1-carboxylate synthase 2-like isoform X1 [KO:K20772] [EC:4.4.1.14]
111479912  1-aminocyclopropane-1-carboxylate synthase [KO:K20772] [EC:4.4.1.14]
111482963  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
111485190  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
111491962  1-aminocyclopropane-1-carboxylate synthase CMA101-like [KO:K01762] [EC:4.4.1.14]
111478535  1-aminocyclopropane-1-carboxylate synthase CMA101-like [KO:K01762] [EC:4.4.1.14]
111496971  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
111497071  1-aminocyclopropane-1-carboxylate synthase CMA101 [KO:K01762] [EC:4.4.1.14]
111483220  1-aminocyclopropane-1-carboxylate synthase 9-like [KO:K01762] [EC:4.4.1.14]
111483239  1-aminocyclopropane-1-carboxylate synthase 9-like [KO:K01762] [EC:4.4.1.14]
111480303  1-aminocyclopropane-1-carboxylate oxidase 5-like [KO:K05933] [EC:1.14.17.4]
111478800  1-aminocyclopropane-1-carboxylate oxidase 3-like [KO:K05933] [EC:1.14.17.4]
111477086  1-aminocyclopropane-1-carboxylate oxidase 5-like [KO:K05933] [EC:1.14.17.4]
111465402  1-aminocyclopropane-1-carboxylate oxidase 1 [KO:K05933] [EC:1.14.17.4]
111497285  1-aminocyclopropane-1-carboxylate oxidase 3 [KO:K05933] [EC:1.14.17.4]
111485921  1-aminocyclopropane-1-carboxylate oxidase 1 [KO:K05933] [EC:1.14.17.4]
111469659  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
111488972  aspartokinase 2, chloroplastic-like isoform X1 [KO:K00928] [EC:2.7.2.4]
111487804  aspartokinase 2, chloroplastic-like isoform X1 [KO:K00928] [EC:2.7.2.4]
111472020  bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic-like isoform X1 [KO:K12524] [EC:2.7.2.4 1.1.1.3]
111487985  uncharacterized protein LOC111487985 [KO:K00133] [EC:1.2.1.11]
111491326  uncharacterized protein LOC111491326 [KO:K00133] [EC:1.2.1.11]
111500161  cystathionine gamma-synthase 1, chloroplastic-like [KO:K01739] [EC:2.5.1.48]
111482275  cystathionine gamma-synthase 1, chloroplastic-like [KO:K01739] [EC:2.5.1.48]
111496411  branched-chain amino acid aminotransferase 1, mitochondrial-like [KO:K00826] [EC:2.6.1.42]
111478065  branched-chain amino acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
111492027  branched-chain amino acid aminotransferase 1, mitochondrial-like [KO:K00826] [EC:2.6.1.42]
111496740  branched-chain amino acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
111478223  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
111470260  alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
111479964  alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
111482939  alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
111468865  glutamate--cysteine ligase, chloroplastic-like [KO:K01919] [EC:6.3.2.2]
111491577  glutamate--cysteine ligase, chloroplastic-like [KO:K01919] [EC:6.3.2.2]
111495981  glutathione synthetase, chloroplastic-like isoform X1 [KO:K21456] [EC:6.3.2.3]
111495982  glutathione synthetase, chloroplastic-like isoform X1 [KO:K21456] [EC:6.3.2.3]
111476984  aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
111480790  aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
111486028  aspartate aminotransferase, mitochondrial-like [KO:K14455] [EC:2.6.1.1]
111468196  aspartate aminotransferase, mitochondrial-like [KO:K14455] [EC:2.6.1.1]
111478240  aspartate aminotransferase, mitochondrial-like [KO:K14455] [EC:2.6.1.1]
111496202  aspartate aminotransferase, chloroplastic-like [KO:K00811] [EC:2.6.1.1]
111491805  aspartate aminotransferase, chloroplastic isoform X1 [KO:K00811] [EC:2.6.1.1]
111480542  thiosulfate/3-mercaptopyruvate sulfurtransferase 1, mitochondrial-like isoform X1 [KO:K01011] [EC:2.8.1.1 2.8.1.2]
111482701  thiosulfate/3-mercaptopyruvate sulfurtransferase 1, mitochondrial-like [KO:K01011] [EC:2.8.1.1 2.8.1.2]
111468835  L-lactate dehydrogenase A-like [KO:K00016] [EC:1.1.1.27]
111491257  L-lactate dehydrogenase A-like [KO:K00016] [EC:1.1.1.27]
111466307  D-cysteine desulfhydrase 2, mitochondrial isoform X1 [KO:K05396] [EC:4.4.1.15]
111495123  putative D-cysteine desulfhydrase 1, mitochondrial isoform X1 [KO:K05396] [EC:4.4.1.15]
111492816  bifunctional D-cysteine desulfhydrase/1-aminocyclopropane-1-carboxylate deaminase, mitochondrial-like [KO:K05396] [EC:4.4.1.15]
111493740  probable L-cysteine desulfhydrase, chloroplastic [KO:K22207] [EC:4.4.1.28]
111468593  probable L-cysteine desulfhydrase, chloroplastic [KO:K22207] [EC:4.4.1.28]
111494766  malate dehydrogenase, cytoplasmic-like [KO:K00025] [EC:1.1.1.37]
111479208  malate dehydrogenase-like isoform X1 [KO:K00025] [EC:1.1.1.37]
111498914  malate dehydrogenase [KO:K00025] [EC:1.1.1.37]
111482765  malate dehydrogenase, mitochondrial [KO:K00026] [EC:1.1.1.37]
111496925  malate dehydrogenase, glyoxysomal [KO:K00026] [EC:1.1.1.37]
111484814  malate dehydrogenase, chloroplastic-like [KO:K00026] [EC:1.1.1.37]
111471234  malate dehydrogenase, chloroplastic [KO:K00026] [EC:1.1.1.37]
111477593  malate dehydrogenase, glyoxysomal-like isoform X1 [KO:K00026] [EC:1.1.1.37]
111480781  malate dehydrogenase, mitochondrial [KO:K00026] [EC:1.1.1.37]
111482202  probable S-sulfocysteine synthase, chloroplastic [KO:K22846] [EC:2.5.1.144]
111479396  D-3-phosphoglycerate dehydrogenase 1, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
111482644  D-3-phosphoglycerate dehydrogenase 1, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
111479899  D-3-phosphoglycerate dehydrogenase 2, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
111493010  D-3-phosphoglycerate dehydrogenase 1, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
111470134  phosphoserine aminotransferase 2, chloroplastic [KO:K00831] [EC:2.6.1.52]
Compound
C00019  S-Adenosyl-L-methionine
C00021  S-Adenosyl-L-homocysteine
C00022  Pyruvate
C00041  L-Alanine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00065  L-Serine
C00073  L-Methionine
C00094  Sulfite
C00097  L-Cysteine
C00109  2-Oxobutanoate
C00155  L-Homocysteine
C00170  5'-Methylthioadenosine
C00197  3-Phospho-D-glycerate
C00263  L-Homoserine
C00283  Hydrogen sulfide
C00409  Methanethiol
C00441  L-Aspartate 4-semialdehyde
C00491  L-Cystine
C00506  L-Cysteate
C00606  3-Sulfino-L-alanine
C00793  D-Cysteine
C00957  Mercaptopyruvate
C00979  O-Acetyl-L-serine
C01005  O-Phospho-L-serine
C01077  O-Acetyl-L-homoserine
C01118  O-Succinyl-L-homoserine
C01137  S-Adenosylmethioninamine
C01180  4-Methylthio-2-oxobutanoic acid
C01234  1-Aminocyclopropane-1-carboxylate
C01817  L-Homocystine
C01962  Thiocysteine
C02218  Dehydroalanine
C02291  L-Cystathionine
C02356  (S)-2-Aminobutanoate
C02989  L-Methionine S-oxide
C03082  4-Phospho-L-aspartate
C03089  5-Methylthio-D-ribose
C03145  N-Formylmethionine
C03232  3-Phosphonooxypyruvate
C03431  S-Inosyl-L-homocysteine
C03539  S-Ribosyl-L-homocysteine
C04188  S-Methyl-5-thio-D-ribose 1-phosphate
C04582  S-Methyl-5-thio-D-ribulose 1-phosphate
C05324  Nicotianamine
C05524  Aminoacyl-L-methionine
C05526  S-Glutathionyl-L-cysteine
C05527  3-Sulfinylpyruvate
C05528  3-Sulfopyruvate
C05823  3-Mercaptolactate
C05824  S-Sulfo-L-cysteine
C06547  Ethylene
C08276  3-(Methylthio)propanoate
C09306  Sulfur dioxide
C11437  1-Deoxy-D-xylulose 5-phosphate
C11481  HSO3-
C11499  (S)-3-Sulfolactate
C11537  (2R)-3-Sulfolactate
C15606  1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one
C15650  2,3-Diketo-5-methylthiopentyl-1-phosphate
C15651  2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate
C18049  N-Acyl-L-homoserine lactone
C19787  5'-S-Methyl-5'-thioinosine
C21015  gamma-L-Glutamyl-L-2-aminobutyrate
C21016  Ophthalmate
C22359  S-Methyl-1-thio-D-xylulose 5-phosphate
Reference
PMID:15102328
  Authors
Sekowska A, Denervaud V, Ashida H, Michoud K, Haas D, Yokota A, Danchin A
  Title
Bacterial variations on the methionine salvage pathway.
  Journal
BMC Microbiol 4:9 (2004)
DOI:10.1186/1471-2180-4-9
Reference
PMID:14551435
  Authors
Ashida H, Saito Y, Kojima C, Kobayashi K, Ogasawara N, Yokota A.
  Title
A functional link between RuBisCO-like protein of Bacillus and photosynthetic RuBisCO.
  Journal
Science 302:286-90 (2003)
DOI:10.1126/science.1086997
Reference
PMID:12022921
  Authors
Sekowska A, Danchin A.
  Title
The methionine salvage pathway in Bacillus subtilis.
  Journal
BMC Microbiol 2:8 (2002)
DOI:10.1186/1471-2180-2-8
Reference
PMID:12670965
  Authors
Berger BJ, English S, Chan G, Knodel MH.
  Title
Methionine regeneration and aminotransferases in Bacillus subtilis, Bacillus cereus, and Bacillus anthracis.
  Journal
J Bacteriol 185:2418-31 (2003)
DOI:10.1128/JB.185.8.2418-2431.2003
Reference
PMID:17169919
  Authors
Goyer A, Collakova E, Shachar-Hill Y, Hanson AD
  Title
Functional characterization of a methionine gamma-lyase in Arabidopsis and its implication in an alternative to the reverse trans-sulfuration pathway.
  Journal
Plant Cell Physiol 48:232-42 (2007)
DOI:10.1093/pcp/pcl055
Reference
PMID:17030798
  Authors
Rebeille F, Jabrin S, Bligny R, Loizeau K, Gambonnet B, Van Wilder V, Douce R, Ravanel S
  Title
Methionine catabolism in Arabidopsis cells is initiated by a gamma-cleavage process and leads to S-methylcysteine and isoleucine syntheses.
  Journal
Proc Natl Acad Sci U S A 103:15687-92 (2006)
DOI:10.1073/pnas.0606195103
Reference
PMID:18625006
  Authors
Pirkov I, Norbeck J, Gustafsson L, Albers E
  Title
A complete inventory of all enzymes in the eukaryotic methionine salvage pathway.
  Journal
FEBS J 275:4111-20 (2008)
DOI:10.1111/j.1742-4658.2008.06552.x
Reference
PMID:18391471
  Authors
Ashida H, Saito Y, Kojima C, Yokota A
  Title
Enzymatic characterization of 5-methylthioribulose-1-phosphate dehydratase of the methionine salvage pathway in Bacillus subtilis.
  Journal
Biosci Biotechnol Biochem 72:959-67 (2008)
DOI:10.1271/bbb.70651
Reference
PMID:10613873
  Authors
Kitabatake M, So MW, Tumbula DL, Soll D
  Title
Cysteine biosynthesis pathway in the archaeon Methanosarcina barkeri encoded by acquired bacterial genes?
  Journal
J Bacteriol 182:143-5 (2000)
DOI:10.1128/JB.182.1.143-145.2000
Reference
PMID:12644499
  Authors
Mino K, Ishikawa K
  Title
Characterization of a novel thermostable O-acetylserine sulfhydrylase from Aeropyrum pernix K1.
  Journal
J Bacteriol 185:2277-84 (2003)
DOI:10.1128/JB.185.7.2277-2284.2003
Reference
PMID:18520135
  Authors
Tanabe S
  Title
Development of assay methods for endogenous inorganic sulfur compounds and sulfurtransferases and evaluation of the physiological functions of bound sulfur.
  Journal
Yakugaku Zasshi 128:881-900 (2008)
DOI:10.1248/yakushi.128.881
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
PMID:19270684
  Authors
Gutierrez JA, Crowder T, Rinaldo-Matthis A, Ho MC, Almo SC, Schramm VL
  Title
Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing.
  Journal
Nat Chem Biol 5:251-7 (2009)
DOI:10.1038/nchembio.153
Related
pathway
cmax00010  Glycolysis / Gluconeogenesis
cmax00250  Alanine, aspartate and glutamate metabolism
cmax00260  Glycine, serine and threonine metabolism
cmax00290  Valine, leucine and isoleucine biosynthesis
cmax00430  Taurine and hypotaurine metabolism
cmax00480  Glutathione metabolism
cmax00620  Pyruvate metabolism
cmax00640  Propanoate metabolism
cmax00770  Pantothenate and CoA biosynthesis
cmax00900  Terpenoid backbone biosynthesis
cmax00920  Sulfur metabolism
KO pathway
ko00270   
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