KEGG   PATHWAY: cvf04814
Entry
cvf04814                    Pathway                                
Name
Motor proteins - Charadrius vociferus (killdeer)
Class
Cellular Processes; Cell motility
Pathway map
cvf04814  Motor proteins
cvf04814

Organism
Charadrius vociferus (killdeer) [GN:cvf]
Gene
104291796  DYNC1H1; LOW QUALITY PROTEIN: cytoplasmic dynein 1 heavy chain 1 [KO:K10413]
104290320  DYNC2H1; cytoplasmic dynein 2 heavy chain 1 [KO:K10414]
104294886  DYNC1I2; cytoplasmic dynein 1 intermediate chain 2 isoform X1 [KO:K10415]
104295596  DYNC1I1; cytoplasmic dynein 1 intermediate chain 1 [KO:K10415]
104292574  DYNC1LI1; cytoplasmic dynein 1 light intermediate chain 1 [KO:K10416]
104283240  DYNC1LI2; cytoplasmic dynein 1 light intermediate chain 2 [KO:K10416]
104282535  DYNC2LI1; cytoplasmic dynein 2 light intermediate chain 1 [KO:K10417]
104289624  DYNLL1; dynein light chain 1, cytoplasmic [KO:K10418]
104289626  dynein light chain 1, cytoplasmic [KO:K10418]
104283300  DYNLL2; dynein light chain 2, cytoplasmic [KO:K10418]
104291198  DYNLRB2; dynein light chain roadblock-type 2 [KO:K10419]
104292704  DYNLRB1; dynein light chain roadblock-type 1 [KO:K10419]
104289423  DYNLT3; dynein light chain Tctex-type 3 [KO:K10420]
104284036  DYNLT1; dynein light chain Tctex-type 1 isoform X1 [KO:K10420]
104292148  TCTE3; tctex1 domain-containing protein 3 [KO:K25419]
104286114  TCTEX1D4; tctex1 domain-containing protein 4 [KO:K25420]
104285537  TCTEX1D1; tctex1 domain-containing protein 1 [KO:K25421]
104291027  DNAH7; dynein heavy chain 7, axonemal [KO:K10408]
104283148  DNAH17; dynein heavy chain 17, axonemal [KO:K10408]
104285316  DNAH5; LOW QUALITY PROTEIN: dynein heavy chain 5, axonemal [KO:K10408]
104287818  DNAH3; dynein heavy chain 3, axonemal [KO:K10408]
104291965  DNAH1; dynein heavy chain 1, axonemal [KO:K10408]
104281559  DNAH11; LOW QUALITY PROTEIN: dynein heavy chain 11, axonemal [KO:K10408]
104282250  DNAH10; dynein heavy chain 10, axonemal [KO:K10408]
104282374  DNAH8; dynein heavy chain 8, axonemal [KO:K10408]
104287238  dynein heavy chain 5, axonemal-like [KO:K10408]
104294712  DNAH9; dynein heavy chain 9, axonemal [KO:K10408]
104295927  DNAH12; dynein heavy chain 12, axonemal [KO:K10408]
104290637  DNAI1; dynein intermediate chain 1, axonemal [KO:K10409]
104287806  DNAI2; dynein intermediate chain 2, axonemal [KO:K11143]
104286305  WDR63; LOW QUALITY PROTEIN: WD repeat-containing protein 63 [KO:K24722]
104285536  WDR78; WD repeat-containing protein 78 [KO:K24723]
104281826  DNALI1; axonemal dynein light intermediate polypeptide 1 [KO:K10410]
104284113  DNAL1; dynein light chain 1, axonemal [KO:K10411]
104283623  DNAL4; dynein light chain 4, axonemal [KO:K10412]
104286980  DCTN1; dynactin subunit 1 [KO:K04648]
104288524  DCTN2; dynactin subunit 2 [KO:K10424]
104290635  DCTN3; dynactin subunit 3 [KO:K10425]
104293154  DCTN4; dynactin subunit 4 [KO:K10426]
104295050  DCTN5; dynactin subunit 5 [KO:K10427]
104287143  DCTN6; dynactin subunit 6 [KO:K10428]
104294623  alpha-centractin [KO:K16575]
104294367  ACTR10; actin-related protein 10 [KO:K16576]
104289486  CAPZA1; F-actin-capping protein subunit alpha-1 [KO:K10364]
104288300  CAPZA2; F-actin-capping protein subunit alpha-2 [KO:K10364]
104281719  CAPZA3; LOW QUALITY PROTEIN: F-actin-capping protein subunit alpha-3 [KO:K10364]
104290810  CAPZB; F-actin-capping protein subunit beta isoform X1 [KO:K10365]
104289653  CCDC64; bicaudal D-related protein 1 [KO:K16756]
104282128  protein Hook homolog 3-like [KO:K16536]
104284915  HOOK3; protein Hook homolog 3 [KO:K16536]
104292329  tubulin alpha-1B chain-like [KO:K07374]
104283170  tubulin alpha-8 chain [KO:K07374]
104285407  tubulin alpha-5 chain [KO:K07374]
104285419  tubulin alpha-5 chain-like [KO:K07374]
104281612  tubulin alpha-4 chain-like [KO:K07374]
104281613  TUBA8; LOW QUALITY PROTEIN: tubulin alpha-8 chain [KO:K07374]
104285871  tubulin alpha-3 chain [KO:K07374]
104284617  tubulin alpha-1D chain-like isoform X1 [KO:K07374]
104284663  TUBAL3; LOW QUALITY PROTEIN: tubulin alpha chain-like 3 [KO:K07374]
104284793  tubulin alpha-1A chain [KO:K07374]
104284810  tubulin alpha-1A chain-like [KO:K07374]
104291133  TUBB3; tubulin beta-3 chain [KO:K07375]
104291255  tubulin beta-7 chain-like [KO:K07375]
104290018  TUBB6; tubulin beta-6 chain [KO:K07375]
104283779  TUBB4B; tubulin beta-4B chain [KO:K07375]
104286634  tubulin beta-2 chain [KO:K07375]
104286635  LOW QUALITY PROTEIN: tubulin beta-2 chain-like [KO:K07375]
104293919  TUBB1; tubulin beta-1 chain isoform X1 [KO:K07375]
104295995  TUBG1; tubulin gamma-1 chain [KO:K10389]
104284359  TUBD1; tubulin delta chain isoform X1 [KO:K10390]
104294064  TUBE1; tubulin epsilon chain [KO:K10391]
104287633  KIF5C; kinesin heavy chain isoform 5C [KO:K10396]
104295370  KIF5B; kinesin-1 heavy chain [KO:K10396]
104291781  KLC1; kinesin light chain 1 isoform X1 [KO:K10407]
104295139  KLC4; kinesin light chain 4 [KO:K10407]
104291970  KIF3A; kinesin-like protein KIF3A [KO:K10394]
104293857  KIF3B; kinesin-like protein KIF3B isoform X1 [KO:K20196]
104293327  KIFAP3; LOW QUALITY PROTEIN: kinesin-associated protein 3 [KO:K25388]
104291171  KIF3C; kinesin-like protein KIF3C [KO:K20197]
104289412  KIF17; LOW QUALITY PROTEIN: kinesin-like protein KIF17 [KO:K20198]
104290463  KIF1B; kinesin-like protein KIF1B isoform X1 [KO:K10392]
104293569  KIF1A; LOW QUALITY PROTEIN: kinesin-like protein KIF1A [KO:K10392]
104295681  KIF13B; kinesin-like protein KIF13B [KO:K17914]
104295981  KIF13A; kinesin-like protein KIF13A [KO:K17914]
104286348  KIF14; kinesin-like protein KIF14 [KO:K17915]
104283264  KIF16B; kinesin-like protein KIF16B [KO:K17916]
104289088  STARD9; stAR-related lipid transfer protein 9 [KO:K16491]
104283496  KIF4A; chromosome-associated kinesin KIF4A [KO:K10395]
104287441  KIF7; kinesin-like protein KIF7 [KO:K18806]
104283198  KIF21B; kinesin-like protein KIF21B [KO:K24185]
104284855  KIF21A; kinesin-like protein KIF21A [KO:K24185]
104291284  KIF27; kinesin-like protein KIF27 [KO:K24186]
104289776  KIF11; kinesin-like protein KIF11 [KO:K10398]
104289794  KIF20B; kinesin-like protein KIF20B [KO:K10402]
104293290  kinesin-like protein KIF20A [KO:K10402]
104293842  KIF20A; kinesin-like protein KIF20A [KO:K10402]
104292675  KIF23; kinesin-like protein KIF23 [KO:K17387]
104286882  CENPE; centromere-associated protein E [KO:K11498]
104293194  KIF18A; kinesin-like protein KIF18A [KO:K10401]
104285300  KIF18B; kinesin-like protein KIF18B [KO:K26156]
104287330  KIF19; kinesin-like protein KIF19 [KO:K26157]
104289688  KIF9; kinesin-like protein KIF9 [KO:K10397]
104282376  KIF6; kinesin-like protein KIF6 [KO:K10397]
104283210  KIF26A; kinesin-like protein KIF26A [KO:K10404]
104294098  KIF26B; kinesin-like protein KIF26B [KO:K10404]
104295291  KIF15; kinesin-like protein KIF15 [KO:K10400]
104292653  kinesin-like protein KIF2A isoform X1 [KO:K10393]
104286115  KIF2C; kinesin-like protein KIF2C [KO:K10393]
104290616  KIF24; kinesin-like protein KIF24 [KO:K10393]
104295722  KIF2A; kinesin-like protein KIF2A isoform X1 [KO:K10393]
104294844  KIFC3; kinesin-like protein KIFC3 [KO:K10406]
104292142  KIF25; kinesin-like protein KIF25 [KO:K18627]
104285294  MYO1D; unconventional myosin-Id [KO:K10356]
104290085  MYO1F; LOW QUALITY PROTEIN: unconventional myosin-If [KO:K10356]
104282236  MYO1H; unconventional myosin-Ih [KO:K10356]
104284480  MYO1A; unconventional myosin-Ia [KO:K10356]
104286556  MYO1C; unconventional myosin-Ic [KO:K10356]
104287042  LOW QUALITY PROTEIN: unconventional myosin-Ig-like [KO:K10356]
104287115  MYO1E; unconventional myosin-Ie [KO:K10356]
104290961  MYO1B; unconventional myosin-Ib isoform X1 [KO:K10356]
104291344  MYO3A; myosin-IIIa [KO:K08834] [EC:2.7.11.1]
104294949  MYO3B; LOW QUALITY PROTEIN: myosin-IIIb [KO:K08834] [EC:2.7.11.1]
104282856  MYO5B; unconventional myosin-Vb [KO:K10357]
104289044  unconventional myosin-Vb-like [KO:K10357]
104287101  MYO5C; unconventional myosin-Vc [KO:K10357]
104287102  MYO5A; unconventional myosin-Va [KO:K10357]
104295944  MYO6; LOW QUALITY PROTEIN: unconventional myosin-VI [KO:K10358]
104283077  MYO7A; unconventional myosin-VIIa [KO:K10359]
104282249  MYO7B; unconventional myosin-VIIb [KO:K21868]
104295408  MYO9B; LOW QUALITY PROTEIN: unconventional myosin-IXb [KO:K10360]
104295783  MYO9A; unconventional myosin-IXa [KO:K10360]
104285307  MYO10; unconventional myosin-X [KO:K12559]
104294962  unconventional myosin-X-like [KO:K12559]
104289590  MYO15A; LOW QUALITY PROTEIN: unconventional myosin-XV [KO:K10361]
104281865  unconventional myosin-XVB-like [KO:K10361]
104292725  MYO16; LOW QUALITY PROTEIN: unconventional myosin-XVI [KO:K17481]
104291628  MYO18A; LOW QUALITY PROTEIN: unconventional myosin-XVIIIa [KO:K10362]
104290106  MYO18B; unconventional myosin-XVIIIb [KO:K10362]
104291877  MYO19; unconventional myosin-XIX [KO:K25838]
104287709  MYH15; myosin-15 isoform X1 [KO:K24220]
104292677  MYH7B; myosin-7B [KO:K24220]
104285576  myosin heavy chain, skeletal muscle, adult-like [KO:K24220]
104286671  myosin-3-like isoform X1 [KO:K24220]
104286676  MYH13; myosin-13 [KO:K24220]
104286677  myosin-3 [KO:K24220]
104294708  myosin heavy chain, skeletal muscle, adult-like [KO:K24220]
104294716  myosin heavy chain, skeletal muscle, adult-like [KO:K24220]
104295654  myosin heavy chain, skeletal muscle, adult-like [KO:K24220]
104295656  myosin heavy chain, skeletal muscle, adult-like [KO:K24220]
104295657  myosin heavy chain, skeletal muscle, adult-like [KO:K24220]
104284354  myosin-6 [KO:K17751]
104285149  LOW QUALITY PROTEIN: myosin-7-like [KO:K17751]
104287837  MYH11; myosin-11 isoform X1 [KO:K10352]
104283660  MYH9; myosin-9 [KO:K10352]
104281939  MYH10; myosin-10 isoform X1 [KO:K10352]
104288722  MYL1; myosin light chain 1/3, skeletal muscle isoform isoform X1 [KO:K05738]
104282417  MYL3; myosin light chain 3 [KO:K12749]
104285387  MYL4; myosin light chain 4 [KO:K12750]
104282221  MYL2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
104285068  MYL7; myosin regulatory light chain 2, atrial isoform [KO:K12754]
104287607  MYL9; myosin regulatory light polypeptide 9 [KO:K12755]
104286519  MYL10; myosin regulatory light chain 10 [KO:K12756]
104281909  myosin regulatory light chain 2, smooth muscle minor isoform-like isoform X1 [KO:K12757]
104281910  myosin regulatory light chain 2, smooth muscle minor isoform isoform X1 [KO:K12757]
104291844  ACTA1; actin, alpha skeletal muscle isoform X1 [KO:K10354]
104289714  ACTA2; actin, aortic smooth muscle isoform X1 [KO:K12313]
104288164  ACTC1; actin, alpha cardiac muscle 1 [KO:K12314]
104282023  actin, gamma-enteric smooth muscle [KO:K12315]
104290146  ACTB; actin, cytoplasmic 1 isoform X1 [KO:K05692]
104291934  TNNC1; troponin C, slow skeletal and cardiac muscles isoform X1 [KO:K05865]
104283165  TNNI1; troponin I, slow skeletal muscle [KO:K10371]
104293965  TNNC2; troponin C, skeletal muscle [KO:K12042]
104292621  TNNI2; troponin I, fast skeletal muscle [KO:K12043]
104292623  TNNT3; troponin T, fast skeletal muscle [KO:K12046]
104283164  TNNT2; LOW QUALITY PROTEIN: troponin T, cardiac muscle [KO:K12045]
104287025  tropomyosin beta chain-like [KO:K10374]
104292236  TPM3; tropomyosin alpha-3 chain isoform X1 [KO:K09290]
104295419  TPM4; tropomyosin alpha-4 chain isoform X1 [KO:K10375]
Reference
PMID:21092854
  Authors
Hirokawa N, Niwa S, Tanaka Y
  Title
Molecular motors in neurons: transport mechanisms and roles in brain function, development, and disease.
  Journal
Neuron 68:610-38 (2010)
DOI:10.1016/j.neuron.2010.09.039
Reference
PMID:25470043 (PDB:4RH7)
  Authors
Schmidt H, Zalyte R, Urnavicius L, Carter AP
  Title
Structure of human cytoplasmic dynein-2 primed for its power stroke.
  Journal
Nature 518:435-438 (2015)
DOI:10.1038/nature14023
Reference
PMID:22398446 (PDB:3VKG 3VKH)
  Authors
Kon T, Oyama T, Shimo-Kon R, Imamula K, Shima T, Sutoh K, Kurisu G
  Title
The 2.8 A crystal structure of the dynein motor domain.
  Journal
Nature 484:345-50 (2012)
DOI:10.1038/nature10955
Reference
PMID:22997337 (PDB:3J1T 3J1U)
  Authors
Redwine WB, Hernandez-Lopez R, Zou S, Huang J, Reck-Peterson SL, Leschziner AE
  Title
Structural basis for microtubule binding and release by dynein.
  Journal
Science 337:1532-1536 (2012)
DOI:10.1126/science.1224151
Reference
PMID:26410600
  Authors
Gibbs KL, Greensmith L, Schiavo G
  Title
Regulation of Axonal Transport by Protein Kinases.
  Journal
Trends Biochem Sci 40:597-610 (2015)
DOI:10.1016/j.tibs.2015.08.003
Reference
PMID:28602352 (PDB:5NUG 5NVS 5NVU 5NW4)
  Authors
Zhang K, Foster HE, Rondelet A, Lacey SE, Bahi-Buisson N, Bird AW, Carter AP
  Title
Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated.
  Journal
Cell 169:1303-1314.e18 (2017)
DOI:10.1016/j.cell.2017.05.025
Reference
PMID:25814576 (PDB:5ADX 5AFR 5AFU)
  Authors
Urnavicius L, Zhang K, Diamant AG, Motz C, Schlager MA, Yu M, Patel NA, Robinson CV, Carter AP
  Title
The structure of the dynactin complex and its interaction with dynein.
  Journal
Science 347:1441-1446 (2015)
DOI:10.1126/science.aaa4080
Reference
PMID:29420470 (PDB:5OWO 6F1T 6F1U 6F1V 6F1Y 6F1Z 6F38 6F3A)
  Authors
Urnavicius L, Lau CK, Elshenawy MM, Morales-Rios E, Motz C, Yildiz A, Carter AP
  Title
Cryo-EM shows how dynactin recruits two dyneins for faster movement.
  Journal
Nature 554:202-206 (2018)
DOI:10.1038/nature25462
Reference
PMID:29662141
  Authors
Reck-Peterson SL, Redwine WB, Vale RD, Carter AP
  Title
The cytoplasmic dynein transport machinery and its many cargoes.
  Journal
Nat Rev Mol Cell Biol 19:382-398 (2018)
DOI:10.1038/s41580-018-0004-3
Reference
PMID:23434508 (PDB:3J2U)
  Authors
Asenjo AB, Chatterjee C, Tan D, DePaoli V, Rice WJ, Diaz-Avalos R, Silvestry M, Sosa H
  Title
Structural model for tubulin recognition and deformation by kinesin-13 microtubule depolymerases.
  Journal
Cell Rep 3:759-68 (2013)
DOI:10.1016/j.celrep.2013.01.030
Reference
PMID:10338210 (PDB:1B7T)
  Authors
Houdusse A, Kalabokis VN, Himmel D, Szent-Gyorgyi AG, Cohen C
  Title
Atomic structure of scallop myosin subfragment S1 complexed with MgADP: a novel conformation of the myosin head.
  Journal
Cell 97:459-70 (1999)
DOI:10.1016/s0092-8674(00)80756-4
Reference
PMID:9428521 (PDB:3KIN)
  Authors
Kozielski F, Sack S, Marx A, Thormahlen M, Schonbrunn E, Biou V, Thompson A, Mandelkow EM, Mandelkow E
  Title
The crystal structure of dimeric kinesin and implications for microtubule-dependent motility.
  Journal
Cell 91:985-94 (1997)
DOI:10.1016/s0092-8674(00)80489-4
Reference
PMID:8316857 (PDB:2MYS)
  Authors
Rayment I, Rypniewski WR, Schmidt-Base K, Smith R, Tomchick DR, Benning MM, Winkelmann DA, Wesenberg G, Holden HM
  Title
Three-dimensional structure of myosin subfragment-1: a molecular motor.
  Journal
Science 261:50-8 (1993)
DOI:10.1126/science.8316857
Reference
PMID:20428469
  Authors
Parker D, Bryant Z, Delp SL
  Title
Coarse-Grained Structural Modeling of Molecular Motors Using Multibody Dynamics.
  Journal
Cell Mol Bioeng 2:366-374 (2009)
DOI:10.1007/s12195-009-0084-4
Reference
PMID:21314430
  Authors
Dominguez R, Holmes KC
  Title
Actin structure and function.
  Journal
Annu Rev Biophys 40:169-86 (2011)
DOI:10.1146/annurev-biophys-042910-155359
Reference
PMID:31919429 (PDB:6KN7 6KN8)
  Authors
Yamada Y, Namba K, Fujii T
  Title
Cardiac muscle thin filament structures reveal calcium regulatory mechanism.
  Journal
Nat Commun 11:153 (2020)
DOI:10.1038/s41467-019-14008-1
Reference
PMID:33912943
  Authors
Kruppa AJ, Buss F
  Title
Motor proteins at the mitochondria-cytoskeleton interface.
  Journal
J Cell Sci 134:239092 (2021)
DOI:10.1242/jcs.226084
KO pathway
ko04814   
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