KEGG   PATHWAY: fca00100
Entry
fca00100                    Pathway                                
Name
Steroid biosynthesis - Felis catus (domestic cat)
Class
Metabolism; Lipid metabolism
Pathway map
fca00100  Steroid biosynthesis
fca00100

Module
fca_M00101  Cholesterol biosynthesis, FPP => cholesterol [PATH:fca00100]
fca_M00103  Cholecalciferol biosynthesis [PATH:fca00100]
Other DBs
GO: 0016126
Organism
Felis catus (domestic cat) [GN:fca]
Gene
101084620  FDFT1; squalene synthase isoform X2 [KO:K00801] [EC:2.5.1.21]
101086537  SQLE; squalene monooxygenase [KO:K00511] [EC:1.14.14.17]
101080651  LSS; lanosterol synthase isoform X1 [KO:K01852] [EC:5.4.99.7]
101083499  CYP51A1; lanosterol 14-alpha demethylase isoform X1 [KO:K05917] [EC:1.14.14.154 1.14.15.36]
101083545  TM7SF2; delta(14)-sterol reductase TM7SF2 [KO:K00222] [EC:1.3.1.70]
101085014  LBR; delta(14)-sterol reductase LBR [KO:K19532] [EC:1.3.1.70]
101096978  MSMO1; methylsterol monooxygenase 1 [KO:K07750] [EC:1.14.18.9]
101096551  NSDHL; sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating isoform X1 [KO:K07748] [EC:1.1.1.170]
101083482  HSD17B7; 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 isoform X2 [KO:K13373] [EC:1.1.1.62 1.1.1.270]
101094572  3-beta-hydroxysteroid-Delta(8), Delta(7)-isomerase [KO:K01824] [EC:5.3.3.5]
101098730  DHCR24; delta(24)-sterol reductase [KO:K09828] [EC:1.3.1.72 1.3.1.-]
101099997  SC5D; lathosterol oxidase [KO:K00227] [EC:1.14.19.20]
101089143  DHCR7; 7-dehydrocholesterol reductase isoform X3 [KO:K00213] [EC:1.3.1.21]
101094134  LIPA; LOW QUALITY PROTEIN: lysosomal acid lipase/cholesteryl ester hydrolase [KO:K01052] [EC:3.1.1.13]
101080585  CEL; bile salt-activated lipase [KO:K12298] [EC:3.1.1.13 3.1.1.3]
101099223  SOAT2; sterol O-acyltransferase 2 isoform X2 [KO:K00637] [EC:2.3.1.26]
101081271  SOAT1; sterol O-acyltransferase 1 isoform X1 [KO:K00637] [EC:2.3.1.26]
101093889  CYP2R1; vitamin D 25-hydroxylase isoform X1 [KO:K07419] [EC:1.14.14.24]
100750221  CYP27B1; 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial isoform X2 [KO:K07438] [EC:1.14.15.18]
101096141  CYP24A1; 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial isoform X2 [KO:K07436] [EC:1.14.15.16]
Compound
C00187  Cholesterol
C00448  trans,trans-Farnesyl diphosphate
C00751  Squalene
C01054  (S)-2,3-Epoxysqualene
C01164  7-Dehydrocholesterol
C01189  Lathosterol
C01561  Calcidiol
C01673  Calcitriol
C01694  Ergosterol
C01724  Lanosterol
C01753  beta-Sitosterol
C01789  Campesterol
C01802  Desmosterol
C01902  Cycloartenol
C01943  Obtusifoliol
C02141  Cycloeucalenol
C02530  Cholesterol ester
C03428  Presqualene diphosphate
C03845  5alpha-Cholest-8-en-3beta-ol
C04525  Fecosterol
C05103  4alpha-Methylzymosterol
C05107  7-Dehydrodesmosterol
C05108  14-Demethyllanosterol
C05109  24,25-Dihydrolanosterol
C05437  Zymosterol
C05439  5alpha-Cholesta-7,24-dien-3beta-ol
C05440  Ergosta-5,7,22,24(28)-tetraen-3beta-ol
C05441  Vitamin D2
C05442  Stigmasterol
C05443  Vitamin D3
C07712  Secalciferol
C08813  Brassicasterol
C08821  Isofucosterol
C08830  24-Methylidenecycloartanol
C11455  4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol
C11508  4alpha-Methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol
C11522  24-Methylenelophenol
C11523  24-Ethylidenelophenol
C15776  4alpha-Methylfecosterol
C15777  Episterol
C15780  5-Dehydroepisterol
C15781  24-Methylenecholesterol
C15782  Delta7-Avenasterol
C15783  5-Dehydroavenasterol
C15808  4alpha-Methylzymosterol-4-carboxylate
C15816  3-Keto-4-methylzymosterol
C15915  4,4-Dimethyl-5alpha-cholesta-8-en-3beta-ol
C18231  Calcitetrol
C21106  24-epi-Campesterol
C22112  4alpha-Carboxy-5alpha-cholesta-8,24-dien-3beta-ol
C22116  3beta-Hydroxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-4alpha-carboxylate
C22119  3beta-Hydroxyergosta-7,24(24(1))-dien-4alpha-carboxylate
C22120  4alpha-Carboxy-stigmasta-7,24(24(1))-dien-3beta-ol
C22121  Cycloeucalenone
C22122  Episterone
C22123  Avenastenone
C22136  Zymosterone
Reference
  Authors
Koshiba K, Kamiya Y.
  Title
[Atarasii Syokubutuhorumon no Kagaku] (In Japanese)
  Journal
Koudansya saientific:199-138 (2002)
Reference
PMID:16531502
  Authors
Morikawa T, Mizutani M, Aoki N, Watanabe B, Saga H, Saito S, Oikawa A, Suzuki H, Sakurai N, Shibata D, Wadano A, Sakata K, Ohta D.
  Title
Cytochrome P450 CYP710A encodes the sterol C-22 desaturase in Arabidopsis and tomato.
  Journal
Plant Cell 18:1008-22 (2006)
DOI:10.1105/tpc.105.036012
Reference
PMID:12777052
  Authors
Lange BM, Ghassemian M.
  Title
Genome organization in Arabidopsis thaliana: a survey for genes involved in isoprenoid and chlorophyll metabolism.
  Journal
Plant Mol Biol 51:925-48 (2003)
DOI:10.1023/A:1023005504702
Related
pathway
fca00120  Primary bile acid biosynthesis
fca00140  Steroid hormone biosynthesis
fca00900  Terpenoid backbone biosynthesis
KO pathway
ko00100   
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