KEGG   PATHWAY: gja03083
Entry
gja03083                    Pathway                                
Name
Polycomb repressive complex - Gekko japonicus (Schlegel's Japanese gecko)
Class
Genetic Information Processing; Chromosome
Pathway map
gja03083  Polycomb repressive complex
gja03083

Organism
Gekko japonicus (Schlegel's Japanese gecko) [GN:gja]
Gene
107123351  EZH1; enhancer of zeste 1 polycomb repressive complex 2 subunit [KO:K17451] [EC:2.1.1.356]
107119624  EZH2; enhancer of zeste 2 polycomb repressive complex 2 subunit [KO:K11430] [EC:2.1.1.356]
107124299  EED; embryonic ectoderm development [KO:K11462]
107121718  SUZ12; SUZ12 polycomb repressive complex 2 subunit [KO:K11463]
107107744  RBBP4; RB binding protein 4, chromatin remodeling factor [KO:K10752]
107115671  PHF1; PHD finger protein 1 [KO:K11467]
107112257  MTF2; metal response element binding transcription factor 2 [KO:K11485]
107118789  PHF19; PHD finger protein 19 [KO:K11486]
107114420  chromosome unknown open reading frame, human C10orf12 [KO:K26260]
107114462  LCOR; ligand dependent nuclear receptor corepressor [KO:K26260]
107118925  AEBP2; AE binding protein 2 [KO:K17452]
107107294  protein Jumonji-like [KO:K11478]
107106808  BAP1; BRCA1 associated protein 1 [KO:K08588] [EC:3.4.19.12]
107123199  ASXL3; additional sex combs like 3, transcriptional regulator [KO:K11471]
107113756  ASXL2; additional sex combs like 2, transcriptional regulator [KO:K11471]
107123015  ASXL1; additional sex combs like 1, transcriptional regulator [KO:K11471]
107108561  OGT; O-linked N-acetylglucosamine (GlcNAc) transferase [KO:K09667] [EC:2.4.1.255]
107108393  host cell factor 1-like [KO:K14966]
107121525  YY1; YY1 transcription factor [KO:K09201]
107120379  MBD5; methyl-CpG binding domain protein 5 [KO:K23219]
107118956  MBD6; methyl-CpG binding domain protein 6 [KO:K26585]
107117309  FOXK1; forkhead box K1 [KO:K09404]
107121873  FOXK2; forkhead box K2 [KO:K09404]
107111755  RNF2; ring finger protein 2 [KO:K10695] [EC:2.3.2.27]
107112069  RING1; ring finger protein 1 [KO:K10695] [EC:2.3.2.27]
107120123  PCGF2; polycomb group ring finger 2 [KO:K11460]
107109392  BMI1; BMI1 proto-oncogene, polycomb ring finger [KO:K11459]
107119859  CBX2; chromobox 2 [KO:K11451]
107119856  CBX4; chromobox 4 [KO:K11452] [EC:2.3.2.-]
107117116  CBX6; chromobox 6 [KO:K11453]
107117115  CBX7; chromobox 7 [KO:K11454]
107119857  CBX8; chromobox 8 [KO:K11455]
107109224  PHC1; polyhomeotic homolog 1 [KO:K11456]
107113363  polyhomeotic-like protein 2 [KO:K11457]
107110783  PHC3; polyhomeotic homolog 3 [KO:K11458]
107115843  sex comb on midleg-like protein 2 [KO:K11465]
107110856  SCMH1; sex comb on midleg homolog 1 (Drosophila) [KO:K11461]
107107218  SFMBT1; Scm-like with four mbt domains 1 [KO:K26269]
107111923  aurora kinase C-like [KO:K11479] [EC:2.7.11.1]
107120722  aurora kinase B-A-like [KO:K11479] [EC:2.7.11.1]
107105760  UBE2D3; ubiquitin conjugating enzyme E2 D3 [KO:K06689] [EC:2.3.2.23]
107114924  ubiquitin-conjugating enzyme E2 D2 [KO:K06689] [EC:2.3.2.23]
107124659  UBE2D1; ubiquitin conjugating enzyme E2 D1 [KO:K06689] [EC:2.3.2.23]
107121900  USP45; ubiquitin specific peptidase 45 [KO:K11844] [EC:3.4.19.12]
107120319  USP16; ubiquitin specific peptidase 16 [KO:K11844] [EC:3.4.19.12]
107126008  RYBP; RING1 and YY1 binding protein [KO:K11469]
107107116  YAF2; YY1 associated factor 2 [KO:K11468]
107121481  PCGF1; polycomb group ring finger 1 [KO:K11487]
107109113  KDM2A; lysine demethylase 2A [KO:K10276] [EC:1.14.11.27]
107115913  lysine-specific demethylase 2B-like [KO:K10276] [EC:1.14.11.27]
107116549  BCOR; BCL6 corepressor [KO:K23215]
107106068  BCORL1; BCL6 corepressor-like 1 [KO:K26199]
107125984  SKP1; S-phase kinase associated protein 1 [KO:K03094]
107125671  USP7; ubiquitin specific peptidase 7 [KO:K11838] [EC:3.4.19.12]
107111776  PCGF3; polycomb group ring finger 3 [KO:K11488]
107109532  PCGF5; polycomb group ring finger 5 [KO:K11489]
107109804  CSNK2B; casein kinase 2 beta [KO:K03115]
107116487  AUTS2; autism susceptibility candidate 2 [KO:K23214]
107111221  FBRS; fibrosin [KO:K26253]
107120984  FBRSL1; fibrosin like 1 [KO:K26254]
107109125  DCAF7; DDB1 and CUL4 associated factor 7 [KO:K11805]
107105536  TEX10; testis expressed 10 [KO:K14827]
107109304  CREBBP; CREB binding protein [KO:K04498] [EC:2.3.1.48]
107117161  EP300; E1A binding protein p300 [KO:K04498] [EC:2.3.1.48]
107117921  PCGF6; polycomb group ring finger 6 [KO:K11470]
107114817  E2F6; E2F transcription factor 6 [KO:K09390]
107110920  TFDP1; transcription factor Dp-1 [KO:K04683]
107121946  MAX; MYC associated factor X [KO:K04453]
107126015  MAX gene-associated protein-like [KO:K23399]
107126016  MAX gene-associated protein-like [KO:K23399]
107105651  L3MBTL1; l(3)mbt-like 1 (Drosophila) [KO:K24387]
107110557  L3MBTL3; l(3)mbt-like 3 (Drosophila) [KO:K24387]
107117139  L3MBTL2; L3MBTL2 polycomb repressive complex 1 subunit [KO:K24387]
107116638  CBX3; chromobox 3 [KO:K11586]
107106566  WDR5; WD repeat domain 5 [KO:K14963]
107107742  HDAC1; histone deacetylase 1 [KO:K06067] [EC:3.5.1.98]
107121973  histone deacetylase 2 [KO:K06067] [EC:3.5.1.98]
Reference
PMID:21881606
  Authors
Richly H, Aloia L, Di Croce L
  Title
Roles of the Polycomb group proteins in stem cells and cancer.
  Journal
Cell Death Dis 2:e204 (2011)
DOI:10.1038/cddis.2011.84
Reference
PMID:28202673
  Authors
Chittock EC, Latwiel S, Miller TC, Muller CW
  Title
Molecular architecture of polycomb repressive complexes.
  Journal
Biochem Soc Trans 45:193-205 (2017)
DOI:10.1042/BST20160173
Reference
PMID:33202645
  Authors
Geng Z, Gao Z
  Title
Mammalian PRC1 Complexes: Compositional Complexity and Diverse Molecular Mechanisms.
  Journal
Int J Mol Sci 21:ijms21228594 (2020)
DOI:10.3390/ijms21228594
Reference
PMID:35681061
  Authors
Kim JJ, Kingston RE
  Title
Context-specific Polycomb mechanisms in development.
  Journal
Nat Rev Genet 23:680-695 (2022)
DOI:10.1038/s41576-022-00499-0
Reference
PMID:36076977
  Authors
Dong GJ, Xu JL, Qi YR, Yuan ZQ, Zhao W
  Title
Critical Roles of Polycomb Repressive Complexes in Transcription and Cancer.
  Journal
Int J Mol Sci 23:ijms23179574 (2022)
DOI:10.3390/ijms23179574
Reference
PMID:37086328
  Authors
Ryan CW, Peirent ER, Regan SL, Guxholli A, Bielas SL
  Title
H2A monoubiquitination: insights from human genetics and animal models.
  Journal
Hum Genet 10.1007/s00439-023-02557-x (2023)
DOI:10.1007/s00439-023-02557-x
KO pathway
ko03083   
LinkDB

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