KEGG   PATHWAY: hsy00230
Entry
hsy00230                    Pathway                                
Name
Purine metabolism - Hydractinia symbiolongicarpus
Class
Metabolism; Nucleotide metabolism
Pathway map
hsy00230  Purine metabolism
hsy00230

Module
hsy_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:hsy00230]
hsy_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:hsy00230]
hsy_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:hsy00230]
hsy_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:hsy00230]
hsy_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:hsy00230]
Other DBs
GO: 0006163 0042278
Organism
Hydractinia symbiolongicarpus [GN:hsy]
Gene
130623575  ADP-ribose pyrophosphatase, mitochondrial-like isoform X1 [KO:K13988] [EC:3.6.1.13]
130645744  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase-like isoform X1 [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
130630659  phosphoglucomutase-1-like [KO:K01835] [EC:5.4.2.2]
130655532  phosphopentomutase-like [KO:K15779] [EC:5.4.2.2 5.4.2.7]
130654405  ribose-phosphate pyrophosphokinase 2-like [KO:K00948] [EC:2.7.6.1]
130654876  amidophosphoribosyltransferase-like [KO:K00764] [EC:2.4.2.14]
130645429  trifunctional purine biosynthetic protein adenosine-3-like [KO:K11787] [EC:6.3.4.13 2.1.2.2 6.3.3.1]
130644335  phosphoribosylformylglycinamidine synthase-like [KO:K01952] [EC:6.3.5.3]
130654877  multifunctional protein ADE2-like [KO:K01587] [EC:4.1.1.21 6.3.2.6]
130655238  multifunctional protein ADE2-like [KO:K01587] [EC:4.1.1.21 6.3.2.6]
130649390  LOW QUALITY PROTEIN: adenylosuccinate lyase-like [KO:K01756] [EC:4.3.2.2]
130621815  bifunctional purine biosynthesis protein ATIC-like [KO:K00602] [EC:2.1.2.3 3.5.4.10]
130613699  adenine phosphoribosyltransferase-like [KO:K00759] [EC:2.4.2.7]
130644654  cytosolic purine 5'-nucleotidase-like isoform X1 [KO:K01081] [EC:3.1.3.5]
130614861  snake venom 5'-nucleotidase-like [KO:K01081] [EC:3.1.3.5]
130640809  snake venom 5'-nucleotidase-like [KO:K19970] [EC:3.1.3.5]
130641184  snake venom 5'-nucleotidase-like [KO:K19970] [EC:3.1.3.5]
130614451  snake venom 5'-nucleotidase-like [KO:K19970] [EC:3.1.3.5]
130613897  purine nucleoside phosphorylase-like [KO:K03783] [EC:2.4.2.1]
130621777  hypoxanthine-guanine phosphoribosyltransferase-like isoform X1 [KO:K00760] [EC:2.4.2.8]
130621779  hypoxanthine-guanine phosphoribosyltransferase-like isoform X1 [KO:K00760] [EC:2.4.2.8]
130653594  inosine-5'-monophosphate dehydrogenase 2-like [KO:K00088] [EC:1.1.1.205]
130656069  nucleoside diphosphate kinase B-like [KO:K00940] [EC:2.7.4.6]
130636055  nucleoside diphosphate kinase 7-like [KO:K00940] [EC:2.7.4.6]
130622478  nucleoside diphosphate kinase B-like [KO:K00940] [EC:2.7.4.6]
130644437  adenylate kinase 9-like [KO:K18533] [EC:2.7.4.3 2.7.4.6]
130656709  ectonucleoside triphosphate diphosphohydrolase 1-like isoform X1 [KO:K01510] [EC:3.6.1.5]
130613749  ectonucleoside triphosphate diphosphohydrolase 2-like [KO:K01510] [EC:3.6.1.5]
130644643  ectonucleoside triphosphate diphosphohydrolase 8-like [KO:K01510] [EC:3.6.1.5]
130648680  soluble calcium-activated nucleotidase 1-like [KO:K12304] [EC:3.6.1.6]
130644271  ectonucleoside triphosphate diphosphohydrolase 7-like [KO:K12305] [EC:3.6.1.6]
130653605  U8 snoRNA-decapping enzyme-like [KO:K16855] [EC:3.6.1.62 3.6.1.64]
130654875  inosine triphosphate pyrophosphatase-like [KO:K01519] [EC:3.6.1.66]
130655556  GMP synthase [glutamine-hydrolyzing]-like [KO:K01951] [EC:6.3.5.2]
130622508  GMP reductase 2-like [KO:K00364] [EC:1.7.1.7]
130641810  uncharacterized protein LOC130641810 isoform X1 [KO:K00942] [EC:2.7.4.8]
130655549  ribonucleoside-diphosphate reductase large subunit-like [KO:K10807] [EC:1.17.4.1]
130654173  ribonucleoside-diphosphate reductase subunit M2 B-like [KO:K10808] [EC:1.17.4.1]
130642034  5'-deoxynucleotidase HDDC2-like [KO:K07023] [EC:3.1.3.89]
130614894  guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1-like [KO:K21138] [EC:3.1.7.2]
130621516  exopolyphosphatase PRUNE1-like [KO:K01514] [EC:3.6.1.11]
130647287  adenylate cyclase type 3-like [KO:K08043] [EC:4.6.1.1]
130648305  adenylate cyclase type 3-like [KO:K08043] [EC:4.6.1.1]
130621182  adenylate cyclase type 5-like [KO:K08046] [EC:4.6.1.1]
130655321  adenylate cyclase type 9-like [KO:K08049] [EC:4.6.1.1]
130613251  adenylate cyclase type 10-like isoform X1 [KO:K11265] [EC:4.6.1.1]
130656078  guanylate cyclase soluble subunit beta-1-like isoform X1 [KO:K12319] [EC:4.6.1.2]
130628940  atrial natriuretic peptide receptor 1-like isoform X1 [KO:K12323] [EC:4.6.1.2]
130622253  retinal guanylyl cyclase 2-like [KO:K12323] [EC:4.6.1.2]
130646582  atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
130647397  atrial natriuretic peptide receptor 1-like isoform X1 [KO:K12323] [EC:4.6.1.2]
130647777  atrial natriuretic peptide receptor 1-like isoform X1 [KO:K12323] [EC:4.6.1.2]
130647415  guanylate cyclase 32E-like isoform X1 [KO:K01769] [EC:4.6.1.2]
130654886  cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A-like isoform X1 [KO:K19021] [EC:3.1.4.17]
130641993  retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta-like [KO:K13758]
130640987  high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like [KO:K13761] [EC:3.1.4.35]
130613108  probable 3',5'-cyclic phosphodiesterase pde-5 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
130645545  cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A-like [KO:K18438] [EC:3.1.4.17 3.1.4.35]
130655162  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11-like isoform X1 [KO:K13298] [EC:3.1.4.17 3.1.4.35]
130645214  cGMP-specific 3',5'-cyclic phosphodiesterase-like [KO:K13298] [EC:3.1.4.17 3.1.4.35]
130622660  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A-like [KO:K13298] [EC:3.1.4.17 3.1.4.35]
130656335  adenylosuccinate synthetase-like [KO:K01939] [EC:6.3.4.4]
130635994  AMP deaminase 2-like isoform X1 [KO:K01490] [EC:3.5.4.6]
130655271  uncharacterized protein LOC130655271 isoform X1 [KO:K00856] [EC:2.7.1.20]
130655814  adenosine deaminase-like [KO:K01488] [EC:3.5.4.4]
130641405  adenosine deaminase-like [KO:K01488] [EC:3.5.4.4]
130657530  adenosine deaminase 2-like isoform X1 [KO:K19572] [EC:3.5.4.4]
130657537  adenosine deaminase 2-like [KO:K19572] [EC:3.5.4.4]
130657756  adenosine deaminase 2-like [KO:K19572] [EC:3.5.4.4]
130656878  adenylate kinase 7-like [KO:K00939] [EC:2.7.4.3]
130612390  adenylate kinase 8-like [KO:K00939] [EC:2.7.4.3]
130646965  adenylate kinase-like [KO:K00939] [EC:2.7.4.3]
130657088  adenylate kinase isoenzyme 6-like [KO:K18532] [EC:2.7.4.3]
130629779  GTP:AMP phosphotransferase AK3, mitochondrial-like [KO:K00944] [EC:2.7.4.10]
130641805  cancer-related nucleoside-triphosphatase homolog [KO:K06928] [EC:3.6.1.15]
130630513  ectonucleotide pyrophosphatase/phosphodiesterase family member 3-like [KO:K01513] [EC:3.1.4.1 3.6.1.9]
130630598  cAMP-specific 3',5'-cyclic phosphodiesterase 4C-like [KO:K13293] [EC:3.1.4.53]
130631298  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B-like isoform X1 [KO:K18437] [EC:3.1.4.53]
130625845  bis(5'-adenosyl)-triphosphatase-like [KO:K01522] [EC:3.6.1.29]
130657383  bis(5'-adenosyl)-triphosphatase enpp4-like [KO:K18424] [EC:3.6.1.29]
130642077  bis(5'-adenosyl)-triphosphatase ENPP4-like [KO:K18424] [EC:3.6.1.29]
130614248  bis(5'-adenosyl)-triphosphatase ENPP4-like [KO:K18424] [EC:3.6.1.29]
130614333  bis(5'-adenosyl)-triphosphatase ENPP4-like [KO:K18424] [EC:3.6.1.29]
130644919  bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase-like [KO:K13811] [EC:2.7.7.4 2.7.1.25]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
hsy00030  Pentose phosphate pathway
hsy00220  Arginine biosynthesis
hsy00250  Alanine, aspartate and glutamate metabolism
hsy00260  Glycine, serine and threonine metabolism
hsy00340  Histidine metabolism
hsy00630  Glyoxylate and dicarboxylate metabolism
hsy00730  Thiamine metabolism
hsy00740  Riboflavin metabolism
hsy00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

DBGET integrated database retrieval system