KEGG   PATHWAY: mdm00270
Entry
mdm00270                    Pathway                                
Name
Cysteine and methionine metabolism - Malus domestica (apple)
Description
Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted from serine (via acetylserine) by transfer of hydrogen sulfide [MD:M00021]. In animals, methionine-derived homocysteine is used as sulfur source and its condensation product with serine (cystathionine) is converted to cysteine [MD:M00338]. Cysteine is metabolized to pyruvate in multiple routes. Methionine is an essential amino acid, which animals cannot synthesize. In bacteria and plants, methionine is synthesized from aspartate [MD:M00017]. S-Adenosylmethionine (SAM), synthesized from methionine and ATP, is a methyl group donor in many important transfer reactions including DNA methylation for regulation of gene expression. SAM may also be used to regenerate methionine in the methionine salvage pathway [MD:M00034].
Class
Metabolism; Amino acid metabolism
Pathway map
mdm00270  Cysteine and methionine metabolism
mdm00270

Module
mdm_M00021  Cysteine biosynthesis, serine => cysteine [PATH:mdm00270]
mdm_M00034  Methionine salvage pathway [PATH:mdm00270]
mdm_M00368  Ethylene biosynthesis, methionine => ethylene [PATH:mdm00270]
Other DBs
GO: 0006534 0006555
Organism
Malus domestica (apple) [GN:mdm]
Gene
103401004  serine acetyltransferase 2-like isoform X1 [KO:K00640] [EC:2.3.1.30]
103427793  serine acetyltransferase 1, chloroplastic [KO:K00640] [EC:2.3.1.30]
103450147  serine acetyltransferase 5-like [KO:K00640] [EC:2.3.1.30]
103455681  serine acetyltransferase 2 [KO:K00640] [EC:2.3.1.30]
103407278  serine acetyltransferase 5-like [KO:K00640] [EC:2.3.1.30]
114819605  serine acetyltransferase 1, chloroplastic-like [KO:K00640] [EC:2.3.1.30]
103448310  cysteine synthase 2 isoform X1 [KO:K01738] [EC:2.5.1.47]
103451006  cysteine synthase [KO:K01738] [EC:2.5.1.47]
103453124  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
103427551  cysteine synthase 2 [KO:K01738] [EC:2.5.1.47]
103434138  cysteine synthase-like isoform X1 [KO:K01738] [EC:2.5.1.47]
103434146  cysteine synthase [KO:K01738] [EC:2.5.1.47]
103436725  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
103408707  cysteine synthase-like isoform X1 [KO:K01738] [EC:2.5.1.47]
103416847  cysteine synthase [KO:K01738] [EC:2.5.1.47]
103413984  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
103401891  L-3-cyanoalanine synthase 1, mitochondrial [KO:K13034] [EC:2.5.1.47 4.4.1.9]
103405317  L-3-cyanoalanine synthase 2, mitochondrial [KO:K13034] [EC:2.5.1.47 4.4.1.9]
103449879  cystathionine beta-lyase, chloroplastic [KO:K01760] [EC:4.4.1.13]
103430706  cystathionine beta-lyase, chloroplastic-like [KO:K01760] [EC:4.4.1.13]
103448967  LOW QUALITY PROTEIN: homocysteine S-methyltransferase 2 [KO:K00547] [EC:2.1.1.10]
103432414  homocysteine S-methyltransferase 2-like [KO:K00547] [EC:2.1.1.10]
103402706  HMT; homocysteine S-methyltransferase 1 [KO:K00547] [EC:2.1.1.10]
103424053  homocysteine S-methyltransferase 3-like [KO:K00547] [EC:2.1.1.10]
103449328  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1-like [KO:K00549] [EC:2.1.1.14]
103453893  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase [KO:K00549] [EC:2.1.1.14]
103422946  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase isoform X1 [KO:K00549] [EC:2.1.1.14]
103450820  S-adenosylmethionine synthase 2-like [KO:K00789] [EC:2.5.1.6]
103450000  S-adenosylmethionine synthase 4 [KO:K00789] [EC:2.5.1.6]
103452632  S-adenosylmethionine synthase 2 [KO:K00789] [EC:2.5.1.6]
103452744  S-adenosylmethionine synthase 2 [KO:K00789] [EC:2.5.1.6]
103433106  S-adenosylmethionine synthase 3 [KO:K00789] [EC:2.5.1.6]
103433836  S-adenosylmethionine synthase 5-like [KO:K00789] [EC:2.5.1.6]
103436288  S-adenosylmethionine synthase 4-like [KO:K00789] [EC:2.5.1.6]
103426242  S-adenosylmethionine synthase 1 [KO:K00789] [EC:2.5.1.6]
114827086  S-adenosylmethionine synthase 1 [KO:K00789] [EC:2.5.1.6]
103453041  S-adenosylmethionine decarboxylase proenzyme 4 [KO:K01611] [EC:4.1.1.50]
103403819  S-adenosylmethionine decarboxylase proenzyme 4-like [KO:K01611] [EC:4.1.1.50]
103451713  SAMDC; uncharacterized protein LOC103451713 [KO:K01611] [EC:4.1.1.50]
103425910  LOW QUALITY PROTEIN: S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
108171783  uncharacterized LOC108171783 [KO:K01611] [EC:4.1.1.50]
103402794  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
103455238  spermidine synthase 2-like [KO:K00797] [EC:2.5.1.16]
103438138  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
103403001  uncharacterized protein LOC103403001 [KO:K00797] [EC:2.5.1.16]
103451952  uncharacterized protein LOC103451952 [KO:K00797] [EC:2.5.1.16]
103406584  LOW QUALITY PROTEIN: spermine synthase-like [KO:K00797] [EC:2.5.1.16]
103417915  spermine synthase-like [KO:K00797] [EC:2.5.1.16]
103420793  spermine synthase-like [KO:K00797] [EC:2.5.1.16]
103420795  spermine synthase-like [KO:K00797] [EC:2.5.1.16]
103450853  LOW QUALITY PROTEIN: nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
103433868  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
114827619  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 2-like [KO:K01244] [EC:3.2.2.16]
103401297  methylthioribose kinase isoform X2 [KO:K00899] [EC:2.7.1.100]
103401300  methylthioribose kinase-like [KO:K00899] [EC:2.7.1.100]
103425089  methylthioribose kinase-like [KO:K00899] [EC:2.7.1.100]
103400927  LOW QUALITY PROTEIN: methylthioribose-1-phosphate isomerase-like [KO:K08963] [EC:5.3.1.23]
103451249  methylthioribose-1-phosphate isomerase-like [KO:K08963] [EC:5.3.1.23]
103448693  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 1 isoform X1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
103422882  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
103453168  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2 [KO:K08967] [EC:1.13.11.53 1.13.11.54]
103403944  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 2-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
103416852  LOW QUALITY PROTEIN: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 1 [KO:K08967] [EC:1.13.11.53 1.13.11.54]
114821499  uncharacterized protein LOC114821499 [KO:K23977] [EC:2.6.1.117]
103450660  LOW QUALITY PROTEIN: uncharacterized protein LOC103450660 [KO:K23977] [EC:2.6.1.117]
103448720  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
103405636  tyrosine aminotransferase-like [KO:K00815] [EC:2.6.1.5]
114824039  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
103429245  aromatic aminotransferase ISS1-like isoform X1 [KO:K00837] [EC:2.6.1.-]
103440674  aromatic aminotransferase ISS1 [KO:K00837] [EC:2.6.1.-]
103446265  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
103437427  methionine gamma-lyase [KO:K01761] [EC:4.4.1.11]
103452551  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
103452459  DNA (cytosine-5)-methyltransferase CMT3 [KO:K00558] [EC:2.1.1.37]
103409483  DNA (cytosine-5)-methyltransferase CMT2 isoform X1 [KO:K00558] [EC:2.1.1.37]
103425030  LOW QUALITY PROTEIN: DNA (cytosine-5)-methyltransferase 1-like [KO:K00558] [EC:2.1.1.37]
103412678  neurofilament heavy polypeptide-like [KO:K00558] [EC:2.1.1.37]
103433929  uncharacterized protein LOC103433929 [KO:K17398] [EC:2.1.1.37]
103450927  uncharacterized protein LOC103450927 [KO:K17398] [EC:2.1.1.37]
103443415  adenosylhomocysteinase [KO:K01251] [EC:3.13.2.1]
103425185  adenosylhomocysteinase [KO:K01251] [EC:3.13.2.1]
103425187  adenosylhomocysteinase-like [KO:K01251] [EC:3.13.2.1]
103411726  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
103428489  1-aminocyclopropane-1-carboxylate synthase 1-like [KO:K20772] [EC:4.4.1.14]
103408235  1-aminocyclopropane-1-carboxylate synthase 1 [KO:K20772] [EC:4.4.1.14]
103439201  1-aminocyclopropane-1-carboxylate synthase [KO:K20772] [EC:4.4.1.14]
103400119  LOW QUALITY PROTEIN: 1-aminocyclopropane-1-carboxylate synthase 8 [KO:K01762] [EC:4.4.1.14]
103406931  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
103415406  1-aminocyclopropane-1-carboxylate synthase 8-like isoform X1 [KO:K01762] [EC:4.4.1.14]
103450091  LOW QUALITY PROTEIN: 1-aminocyclopropane-1-carboxylate synthase 7 [KO:K01762] [EC:4.4.1.14]
103405045  1-aminocyclopropane-1-carboxylate synthase isoform X1 [KO:K01762] [EC:4.4.1.14]
103430893  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
103443111  LOW QUALITY PROTEIN: 1-aminocyclopropane-1-carboxylate synthase 8-like [KO:K01762] [EC:4.4.1.14]
114821009  1-aminocyclopropane-1-carboxylate synthase [KO:K01762] [EC:4.4.1.14]
103453365  1-aminocyclopropane-1-carboxylate oxidase [KO:K05933] [EC:1.14.17.4]
103400792  1-aminocyclopropane-1-carboxylate oxidase 1 [KO:K05933] [EC:1.14.17.4]
103404960  1-aminocyclopropane-1-carboxylate oxidase [KO:K05933] [EC:1.14.17.4]
103434461  1-aminocyclopropane-1-carboxylate oxidase 2 [KO:K05933] [EC:1.14.17.4]
103446762  1-aminocyclopropane-1-carboxylate oxidase 1 [KO:K05933] [EC:1.14.17.4]
103411280  1-aminocyclopropane-1-carboxylate oxidase [KO:K05933] [EC:1.14.17.4]
103433177  aspartokinase 1, chloroplastic isoform X1 [KO:K00928] [EC:2.7.2.4]
103421581  aspartokinase 2, chloroplastic-like isoform X3 [KO:K00928] [EC:2.7.2.4]
103425766  aspartokinase 2, chloroplastic-like isoform X1 [KO:K00928] [EC:2.7.2.4]
103411884  LOW QUALITY PROTEIN: bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic-like [KO:K12524] [EC:2.7.2.4 1.1.1.3]
103425227  bifunctional aspartokinase/homoserine dehydrogenase 1, chloroplastic-like isoform X1 [KO:K12524] [EC:2.7.2.4 1.1.1.3]
103444584  uncharacterized protein LOC103444584 [KO:K00133] [EC:1.2.1.11]
103451531  uncharacterized protein LOC103451531 [KO:K00133] [EC:1.2.1.11]
103404615  cystathionine gamma-synthase 1, chloroplastic-like [KO:K01739] [EC:2.5.1.48]
103432045  cystathionine gamma-synthase 1, chloroplastic-like [KO:K01739] [EC:2.5.1.48]
103445182  branched-chain-amino-acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
103436475  putative branched-chain-amino-acid aminotransferase 7 [KO:K00826] [EC:2.6.1.42]
103455852  branched-chain-amino-acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
103436029  branched-chain amino acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
103431826  branched-chain amino acid aminotransferase 2, chloroplastic-like isoform X1 [KO:K00826] [EC:2.6.1.42]
103428748  branched-chain-amino-acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
103425095  branched-chain amino acid aminotransferase 2, chloroplastic-like isoform X1 [KO:K00826] [EC:2.6.1.42]
114824835  LOW QUALITY PROTEIN: putative branched-chain-amino-acid aminotransferase 7 [KO:K00826] [EC:2.6.1.42]
103450725  alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
103433731  alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
103416128  alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
103403980  glutamate--cysteine ligase, chloroplastic-like isoform X1 [KO:K01919] [EC:6.3.2.2]
103424413  LOW QUALITY PROTEIN: glutamate--cysteine ligase, chloroplastic-like [KO:K01919] [EC:6.3.2.2]
114825636  glutamate--cysteine ligase, chloroplastic-like [KO:K01919] [EC:6.3.2.2]
103433984  glutathione synthetase, chloroplastic-like [KO:K21456] [EC:6.3.2.3]
103450967  LOW QUALITY PROTEIN: glutathione synthetase, chloroplastic [KO:K21456] [EC:6.3.2.3]
103441178  aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
103410741  aspartate aminotransferase, cytoplasmic-like [KO:K14454] [EC:2.6.1.1]
103415469  aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
103405859  aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
103440751  aspartate aminotransferase, chloroplastic [KO:K00811] [EC:2.6.1.1]
103445864  thiosulfate/3-mercaptopyruvate sulfurtransferase 1, mitochondrial-like [KO:K01011] [EC:2.8.1.1 2.8.1.2]
103435398  thiosulfate/3-mercaptopyruvate sulfurtransferase 1, mitochondrial-like [KO:K01011] [EC:2.8.1.1 2.8.1.2]
103419846  thiosulfate/3-mercaptopyruvate sulfurtransferase 1, mitochondrial-like [KO:K01011] [EC:2.8.1.1 2.8.1.2]
103403474  L-lactate dehydrogenase B [KO:K00016] [EC:1.1.1.27]
103455678  bifunctional D-cysteine desulfhydrase/1-aminocyclopropane-1-carboxylate deaminase, mitochondrial [KO:K05396] [EC:4.4.1.15]
103452055  D-cysteine desulfhydrase 2, mitochondrial isoform X1 [KO:K05396] [EC:4.4.1.15]
114825426  putative D-cysteine desulfhydrase 1, mitochondrial [KO:K05396] [EC:4.4.1.15]
103419434  probable L-cysteine desulfhydrase, chloroplastic [KO:K22207] [EC:4.4.1.28]
103450813  probable L-cysteine desulfhydrase, chloroplastic [KO:K22207] [EC:4.4.1.28]
103450812  probable L-cysteine desulfhydrase, chloroplastic [KO:K22207] [EC:4.4.1.28]
103453451  malate dehydrogenase [KO:K00025] [EC:1.1.1.37]
103405182  malate dehydrogenase-like [KO:K00025] [EC:1.1.1.37]
103435358  malate dehydrogenase-like isoform X1 [KO:K00025] [EC:1.1.1.37]
114827711  malate dehydrogenase-like isoform X1 [KO:K00025] [EC:1.1.1.37]
103455965  malate dehydrogenase, glyoxysomal-like [KO:K00026] [EC:1.1.1.37]
103437822  malate dehydrogenase, chloroplastic [KO:K00026] [EC:1.1.1.37]
103436249  malate dehydrogenase, glyoxysomal [KO:K00026] [EC:1.1.1.37]
103405405  malate dehydrogenase, glyoxysomal [KO:K00026] [EC:1.1.1.37]
103431524  malate dehydrogenase, mitochondrial [KO:K00026] [EC:1.1.1.37]
103424543  malate dehydrogenase, chloroplastic-like [KO:K00026] [EC:1.1.1.37]
103448751  LOW QUALITY PROTEIN: malate dehydrogenase, mitochondrial-like [KO:K00026] [EC:1.1.1.37]
103413454  S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent), chloroplastic-like [KO:K22846] [EC:2.5.1.144]
103453917  S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent), chloroplastic-like [KO:K22846] [EC:2.5.1.144]
103405207  D-3-phosphoglycerate dehydrogenase 2, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
103443230  D-3-phosphoglycerate dehydrogenase 2, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
103436439  D-3-phosphoglycerate dehydrogenase 1, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
103401006  phosphoserine aminotransferase 1, chloroplastic-like [KO:K00831] [EC:2.6.1.52]
103454697  phosphoserine aminotransferase 1, chloroplastic-like [KO:K00831] [EC:2.6.1.52]
Compound
C00019  S-Adenosyl-L-methionine
C00021  S-Adenosyl-L-homocysteine
C00022  Pyruvate
C00041  L-Alanine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00065  L-Serine
C00073  L-Methionine
C00094  Sulfite
C00097  L-Cysteine
C00109  2-Oxobutanoate
C00155  L-Homocysteine
C00170  5'-Methylthioadenosine
C00197  3-Phospho-D-glycerate
C00263  L-Homoserine
C00283  Hydrogen sulfide
C00409  Methanethiol
C00441  L-Aspartate 4-semialdehyde
C00491  L-Cystine
C00506  L-Cysteate
C00606  3-Sulfino-L-alanine
C00793  D-Cysteine
C00957  Mercaptopyruvate
C00979  O-Acetyl-L-serine
C01005  O-Phospho-L-serine
C01077  O-Acetyl-L-homoserine
C01118  O-Succinyl-L-homoserine
C01137  S-Adenosylmethioninamine
C01180  4-Methylthio-2-oxobutanoic acid
C01234  1-Aminocyclopropane-1-carboxylate
C01817  L-Homocystine
C01962  Thiocysteine
C02218  Dehydroalanine
C02291  L-Cystathionine
C02356  (S)-2-Aminobutanoate
C02989  L-Methionine S-oxide
C03082  4-Phospho-L-aspartate
C03089  5-Methylthio-D-ribose
C03145  N-Formylmethionine
C03232  3-Phosphonooxypyruvate
C03431  S-Inosyl-L-homocysteine
C03539  S-Ribosyl-L-homocysteine
C04188  S-Methyl-5-thio-D-ribose 1-phosphate
C04582  S-Methyl-5-thio-D-ribulose 1-phosphate
C05324  Nicotianamine
C05524  Aminoacyl-L-methionine
C05526  S-Glutathionyl-L-cysteine
C05527  3-Sulfinylpyruvate
C05528  3-Sulfopyruvate
C05823  3-Mercaptolactate
C05824  S-Sulfo-L-cysteine
C06547  Ethylene
C08276  3-(Methylthio)propanoate
C09306  Sulfur dioxide
C11437  1-Deoxy-D-xylulose 5-phosphate
C11481  HSO3-
C11499  (S)-3-Sulfolactate
C11537  (2R)-3-Sulfolactate
C15606  1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one
C15650  2,3-Diketo-5-methylthiopentyl-1-phosphate
C15651  2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate
C18049  N-Acyl-L-homoserine lactone
C19787  5'-S-Methyl-5'-thioinosine
C21015  gamma-L-Glutamyl-L-2-aminobutyrate
C21016  Ophthalmate
C22359  S-Methyl-1-thio-D-xylulose 5-phosphate
Reference
PMID:15102328
  Authors
Sekowska A, Denervaud V, Ashida H, Michoud K, Haas D, Yokota A, Danchin A
  Title
Bacterial variations on the methionine salvage pathway.
  Journal
BMC Microbiol 4:9 (2004)
DOI:10.1186/1471-2180-4-9
Reference
PMID:14551435
  Authors
Ashida H, Saito Y, Kojima C, Kobayashi K, Ogasawara N, Yokota A.
  Title
A functional link between RuBisCO-like protein of Bacillus and photosynthetic RuBisCO.
  Journal
Science 302:286-90 (2003)
DOI:10.1126/science.1086997
Reference
PMID:12022921
  Authors
Sekowska A, Danchin A.
  Title
The methionine salvage pathway in Bacillus subtilis.
  Journal
BMC Microbiol 2:8 (2002)
DOI:10.1186/1471-2180-2-8
Reference
PMID:12670965
  Authors
Berger BJ, English S, Chan G, Knodel MH.
  Title
Methionine regeneration and aminotransferases in Bacillus subtilis, Bacillus cereus, and Bacillus anthracis.
  Journal
J Bacteriol 185:2418-31 (2003)
DOI:10.1128/JB.185.8.2418-2431.2003
Reference
PMID:17169919
  Authors
Goyer A, Collakova E, Shachar-Hill Y, Hanson AD
  Title
Functional characterization of a methionine gamma-lyase in Arabidopsis and its implication in an alternative to the reverse trans-sulfuration pathway.
  Journal
Plant Cell Physiol 48:232-42 (2007)
DOI:10.1093/pcp/pcl055
Reference
PMID:17030798
  Authors
Rebeille F, Jabrin S, Bligny R, Loizeau K, Gambonnet B, Van Wilder V, Douce R, Ravanel S
  Title
Methionine catabolism in Arabidopsis cells is initiated by a gamma-cleavage process and leads to S-methylcysteine and isoleucine syntheses.
  Journal
Proc Natl Acad Sci U S A 103:15687-92 (2006)
DOI:10.1073/pnas.0606195103
Reference
PMID:18625006
  Authors
Pirkov I, Norbeck J, Gustafsson L, Albers E
  Title
A complete inventory of all enzymes in the eukaryotic methionine salvage pathway.
  Journal
FEBS J 275:4111-20 (2008)
DOI:10.1111/j.1742-4658.2008.06552.x
Reference
PMID:18391471
  Authors
Ashida H, Saito Y, Kojima C, Yokota A
  Title
Enzymatic characterization of 5-methylthioribulose-1-phosphate dehydratase of the methionine salvage pathway in Bacillus subtilis.
  Journal
Biosci Biotechnol Biochem 72:959-67 (2008)
DOI:10.1271/bbb.70651
Reference
PMID:10613873
  Authors
Kitabatake M, So MW, Tumbula DL, Soll D
  Title
Cysteine biosynthesis pathway in the archaeon Methanosarcina barkeri encoded by acquired bacterial genes?
  Journal
J Bacteriol 182:143-5 (2000)
DOI:10.1128/JB.182.1.143-145.2000
Reference
PMID:12644499
  Authors
Mino K, Ishikawa K
  Title
Characterization of a novel thermostable O-acetylserine sulfhydrylase from Aeropyrum pernix K1.
  Journal
J Bacteriol 185:2277-84 (2003)
DOI:10.1128/JB.185.7.2277-2284.2003
Reference
PMID:18520135
  Authors
Tanabe S
  Title
Development of assay methods for endogenous inorganic sulfur compounds and sulfurtransferases and evaluation of the physiological functions of bound sulfur.
  Journal
Yakugaku Zasshi 128:881-900 (2008)
DOI:10.1248/yakushi.128.881
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
PMID:19270684
  Authors
Gutierrez JA, Crowder T, Rinaldo-Matthis A, Ho MC, Almo SC, Schramm VL
  Title
Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing.
  Journal
Nat Chem Biol 5:251-7 (2009)
DOI:10.1038/nchembio.153
Related
pathway
mdm00010  Glycolysis / Gluconeogenesis
mdm00250  Alanine, aspartate and glutamate metabolism
mdm00260  Glycine, serine and threonine metabolism
mdm00290  Valine, leucine and isoleucine biosynthesis
mdm00430  Taurine and hypotaurine metabolism
mdm00480  Glutathione metabolism
mdm00620  Pyruvate metabolism
mdm00640  Propanoate metabolism
mdm00770  Pantothenate and CoA biosynthesis
mdm00900  Terpenoid backbone biosynthesis
mdm00920  Sulfur metabolism
KO pathway
ko00270   
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