KEGG   PATHWAY: msyl00230
Entry
msyl00230                   Pathway                                
Name
Purine metabolism - Malus sylvestris (European crab apple)
Class
Metabolism; Nucleotide metabolism
Pathway map
msyl00230  Purine metabolism
msyl00230

Module
msyl_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:msyl00230]
msyl_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:msyl00230]
msyl_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:msyl00230]
msyl_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:msyl00230]
msyl_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:msyl00230]
Other DBs
GO: 0006163 0042278
Organism
Malus sylvestris (European crab apple) [GN:msyl]
Gene
126600770  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
126623685  nudix hydrolase 2-like [KO:K26956] [EC:3.6.1.13 3.6.1.22]
126634340  nudix hydrolase 2-like [KO:K26956] [EC:3.6.1.13 3.6.1.22]
126609929  nudix hydrolase 2-like [KO:K26956] [EC:3.6.1.13 3.6.1.22]
126591507  nudix hydrolase 10-like [KO:K26956] [EC:3.6.1.13 3.6.1.22]
126634339  nudix hydrolase 2-like [KO:K26956] [EC:3.6.1.13 3.6.1.22]
126584144  nudix hydrolase 2 isoform X1 [KO:K26956] [EC:3.6.1.13 3.6.1.22]
126600927  nudix hydrolase 23, chloroplastic-like isoform X1 [KO:K18453] [EC:3.6.1.13 3.6.1.18]
126594388  nudix hydrolase 23, chloroplastic-like isoform X1 [KO:K18453] [EC:3.6.1.13 3.6.1.18]
126618402  nudix hydrolase 14, chloroplastic [KO:K18447] [EC:3.6.1.21]
126629077  phosphoglucomutase, chloroplastic-like [KO:K01835] [EC:5.4.2.2]
126606329  phosphoglucomutase, cytoplasmic [KO:K01835] [EC:5.4.2.2]
126623623  phosphoglucomutase, chloroplastic [KO:K01835] [EC:5.4.2.2]
126609836  ribose-phosphate pyrophosphokinase 1 [KO:K00948] [EC:2.7.6.1]
126625717  ribose-phosphate pyrophosphokinase 1-like [KO:K00948] [EC:2.7.6.1]
126628804  ribose-phosphate pyrophosphokinase 1-like [KO:K00948] [EC:2.7.6.1]
126584941  amidophosphoribosyltransferase, chloroplastic-like [KO:K00764] [EC:2.4.2.14]
126624622  amidophosphoribosyltransferase, chloroplastic-like [KO:K00764] [EC:2.4.2.14]
126602423  phosphoribosylamine--glycine ligase-like isoform X1 [KO:K01945] [EC:6.3.4.13]
126632129  phosphoribosylamine--glycine ligase-like [KO:K01945] [EC:6.3.4.13]
126587491  phosphoribosylglycinamide formyltransferase, chloroplastic-like [KO:K00601] [EC:2.1.2.2]
126615111  phosphoribosylglycinamide formyltransferase, chloroplastic-like [KO:K00601] [EC:2.1.2.2]
126615757  probable phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial [KO:K01952] [EC:6.3.5.3]
126619957  probable phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial [KO:K01952] [EC:6.3.5.3]
126631053  phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic/mitochondrial-like isoform X1 [KO:K01933] [EC:6.3.3.1]
126631054  phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic/mitochondrial-like [KO:K01933] [EC:6.3.3.1]
126631055  phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic/mitochondrial-like [KO:K01933] [EC:6.3.3.1]
126605417  phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic/mitochondrial-like [KO:K01933] [EC:6.3.3.1]
126605420  phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic/mitochondrial-like [KO:K01933] [EC:6.3.3.1]
126623683  phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic/mitochondrial-like [KO:K01933] [EC:6.3.3.1]
126619431  phosphoribosylaminoimidazole carboxylase, chloroplastic-like isoform X1 [KO:K11808] [EC:4.1.1.21]
126594208  phosphoribosylaminoimidazole carboxylase, chloroplastic-like isoform X1 [KO:K11808] [EC:4.1.1.21]
126631699  phosphoribosylaminoimidazole-succinocarboxamide synthase, chloroplastic-like [KO:K01923] [EC:6.3.2.6]
126605408  phosphoribosylaminoimidazole-succinocarboxamide synthase, chloroplastic-like [KO:K01923] [EC:6.3.2.6]
126619312  uncharacterized protein LOC126619312 [KO:K01756] [EC:4.3.2.2]
126598363  uncharacterized protein LOC126598363 isoform X1 [KO:K00602] [EC:2.1.2.3 3.5.4.10]
126592728  uncharacterized protein LOC126592728 [KO:K00602] [EC:2.1.2.3 3.5.4.10]
126627094  adenine phosphoribosyltransferase 3-like [KO:K00759] [EC:2.4.2.7]
126601721  adenine phosphoribosyltransferase 1-like [KO:K00759] [EC:2.4.2.7]
126617769  adenine phosphoribosyltransferase 3 [KO:K00759] [EC:2.4.2.7]
126631988  adenine phosphoribosyltransferase 1-like [KO:K00759] [EC:2.4.2.7]
126631990  adenine phosphoribosyltransferase 1, chloroplastic-like [KO:K00759] [EC:2.4.2.7]
126604104  adenine phosphoribosyltransferase 5-like isoform X1 [KO:K00759] [EC:2.4.2.7]
126632242  adenine phosphoribosyltransferase 5-like isoform X1 [KO:K00759] [EC:2.4.2.7]
126583145  uncharacterized protein LOC126583145 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
126597477  uncharacterized protein LOC126597477 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
126609388  uncharacterized protein LOC126609388 isoform X1 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
126585044  uncharacterized protein LOC126585044 [KO:K00760] [EC:2.4.2.8]
126624496  uncharacterized protein LOC126624496 [KO:K00760] [EC:2.4.2.8]
126586787  inosine-5'-monophosphate dehydrogenase 2-like [KO:K00088] [EC:1.1.1.205]
126586788  inosine-5'-monophosphate dehydrogenase 2-like [KO:K00088] [EC:1.1.1.205]
126624598  inosine-5'-monophosphate dehydrogenase 2-like [KO:K00088] [EC:1.1.1.205]
126625316  nucleoside diphosphate kinase III, chloroplastic/mitochondrial-like [KO:K00940] [EC:2.7.4.6]
126626688  nucleoside diphosphate kinase 2, chloroplastic-like [KO:K00940] [EC:2.7.4.6]
126599668  nucleoside diphosphate kinase III, chloroplastic/mitochondrial-like [KO:K00940] [EC:2.7.4.6]
126600922  nucleoside diphosphate kinase 2, chloroplastic [KO:K00940] [EC:2.7.4.6]
126629554  nucleoside diphosphate kinase 1 [KO:K00940] [EC:2.7.4.6]
126589858  probable apyrase 6 [KO:K01510] [EC:3.6.1.5]
126607129  probable apyrase 6 isoform X1 [KO:K01510] [EC:3.6.1.5]
126596945  probable apyrase 6 isoform X1 [KO:K01510] [EC:3.6.1.5]
126599230  apyrase 2-like [KO:K14641] [EC:3.6.1.5]
126593669  apyrase 2-like [KO:K14641] [EC:3.6.1.5]
126596168  inosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
126614755  xanthine dehydrogenase 1-like isoform X1 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
126588952  xanthine dehydrogenase 1-like isoform X1 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
126589823  xanthine dehydrogenase 1-like isoform X1 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
126606233  nudix hydrolase 25-like [KO:K26955] [EC:3.6.1.17]
126595717  nudix hydrolase 25-like [KO:K26955] [EC:3.6.1.17]
126626415  uncharacterized protein LOC126626415 [KO:K01951] [EC:6.3.5.2]
126600634  uncharacterized protein LOC126600634 [KO:K01951] [EC:6.3.5.2]
126599247  guanylate kinase 2-like [KO:K00942] [EC:2.7.4.8]
126593049  guanylate kinase 2-like isoform X1 [KO:K00942] [EC:2.7.4.8]
126606373  guanylate kinase 2, chloroplastic/mitochondrial-like [KO:K00942] [EC:2.7.4.8]
126596822  guanylate kinase 2, chloroplastic/mitochondrial-like [KO:K00942] [EC:2.7.4.8]
126627882  ribonucleoside-diphosphate reductase large subunit-like [KO:K10807] [EC:1.17.4.1]
126604459  ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
126597766  ribonucleoside-diphosphate reductase small chain A-like [KO:K10808] [EC:1.17.4.1]
126609785  ribonucleoside-diphosphate reductase small chain-like [KO:K10808] [EC:1.17.4.1]
126583853  ribonucleoside-diphosphate reductase small chain [KO:K10808] [EC:1.17.4.1]
126606832  ribonucleoside-diphosphate reductase small chain A-like isoform X1 [KO:K10808] [EC:1.17.4.1]
126597725  uncharacterized protein LOC126597725 [KO:K07023] [EC:3.1.3.89]
126594899  uncharacterized protein LOC126594899 [KO:K07023] [EC:3.1.3.89]
126607502  5'-deoxynucleotidase hdd1 [KO:K07023] [EC:3.1.3.89]
126587950  uncharacterized protein LOC126587950 isoform X1 [KO:K01514] [EC:3.6.1.11]
126623732  uncharacterized protein LOC126623732 isoform X1 [KO:K01514] [EC:3.6.1.11]
126609888  probable GTP diphosphokinase RSH2, chloroplastic [KO:K00951] [EC:2.7.6.5]
126616747  putative GTP diphosphokinase RSH1, chloroplastic [KO:K00951] [EC:2.7.6.5]
126591294  putative GTP diphosphokinase RSH1, chloroplastic [KO:K00951] [EC:2.7.6.5]
126596174  probable GTP diphosphokinase CRSH, chloroplastic [KO:K00951] [EC:2.7.6.5]
126581936  probable GTP diphosphokinase RSH2, chloroplastic [KO:K00951] [EC:2.7.6.5]
126607642  phytosulfokine receptor 1-like isoform X1 [KO:K27625] [EC:2.7.11.1 4.6.1.2]
126597521  phytosulfokine receptor 1 [KO:K27625] [EC:2.7.11.1 4.6.1.2]
126586693  adenylosuccinate synthetase 2, chloroplastic-like [KO:K01939] [EC:6.3.4.4]
126603163  adenylosuccinate synthetase 2, chloroplastic-like [KO:K01939] [EC:6.3.4.4]
126623293  adenylosuccinate synthetase 2, chloroplastic-like [KO:K01939] [EC:6.3.4.4]
126619188  AMP deaminase-like [KO:K01490] [EC:3.5.4.6]
126597029  AMP deaminase-like [KO:K01490] [EC:3.5.4.6]
126629781  adenosine kinase 2 [KO:K00856] [EC:2.7.1.20]
126630725  adenosine kinase 2-like [KO:K00856] [EC:2.7.1.20]
126617793  adenosine kinase 2-like isoform X1 [KO:K00856] [EC:2.7.1.20]
126593812  adenosine kinase 2-like isoform X1 [KO:K00856] [EC:2.7.1.20]
126626085  adenylate kinase 4 [KO:K00939] [EC:2.7.4.3]
126610954  probable adenylate kinase 7, mitochondrial [KO:K00939] [EC:2.7.4.3]
126599682  adenylate kinase 4-like [KO:K00939] [EC:2.7.4.3]
126627369  probable adenylate kinase 7, mitochondrial [KO:K00939] [EC:2.7.4.3]
126614036  adenylate kinase 5, chloroplastic isoform X1 [KO:K00939] [EC:2.7.4.3]
126630576  probable adenylate kinase 6, chloroplastic [KO:K00939] [EC:2.7.4.3]
126603519  adenylate kinase, chloroplastic [KO:K00939] [EC:2.7.4.3]
126632127  adenylate kinase 2, chloroplastic-like isoform X1 [KO:K00939] [EC:2.7.4.3]
126618840  adenylate kinase 1, chloroplastic-like [KO:K00939] [EC:2.7.4.3]
126633373  adenylate kinase 4-like [KO:K00939] [EC:2.7.4.3]
126633570  probable adenylate kinase 6, chloroplastic [KO:K00939] [EC:2.7.4.3]
126593675  adenylate kinase 1, chloroplastic-like [KO:K00939] [EC:2.7.4.3]
126587546  adenylate kinase isoenzyme 6 homolog [KO:K18532] [EC:2.7.4.3]
126605000  uncharacterized protein LOC126605000 isoform X1 [KO:K06928] [EC:3.6.1.15]
126605085  uncharacterized protein LOC126605085 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
126605522  uncharacterized protein LOC126605522 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
126589701  bifunctional bis(5'-adenosyl)-triphosphatase/adenylylsulfatase FHIT-like [KO:K01522] [EC:3.6.1.29]
126616671  bifunctional bis(5'-adenosyl)-triphosphatase/adenylylsulfatase FHIT [KO:K01522] [EC:3.6.1.29]
126603143  ATP sulfurylase 2-like [KO:K13811] [EC:2.7.7.4 2.7.1.25]
126633443  ATP sulfurylase 2-like [KO:K13811] [EC:2.7.7.4 2.7.1.25]
126607238  ATP sulfurylase 1, chloroplastic [KO:K13811] [EC:2.7.7.4 2.7.1.25]
126596919  ATP sulfurylase 1, chloroplastic-like [KO:K13811] [EC:2.7.7.4 2.7.1.25]
126601009  adenylyl-sulfate kinase 3-like isoform X1 [KO:K00860] [EC:2.7.1.25]
126587534  adenylyl-sulfate kinase 3-like [KO:K00860] [EC:2.7.1.25]
126603528  adenylyl-sulfate kinase 1, chloroplastic-like isoform X1 [KO:K00860] [EC:2.7.1.25]
126594270  adenylyl-sulfate kinase 3-like [KO:K00860] [EC:2.7.1.25]
126609350  adenylyl-sulfate kinase 3-like isoform X1 [KO:K00860] [EC:2.7.1.25]
126624649  adenylyl-sulfate kinase 3-like [KO:K00860] [EC:2.7.1.25]
126610121  uricase-2 isozyme 1-like isoform X1 [KO:K00365] [EC:1.7.3.3]
126629916  uricase-2-like [KO:K00365] [EC:1.7.3.3]
126629868  uric acid degradation bifunctional protein TTL isoform X1 [KO:K13484] [EC:3.5.2.17 4.1.1.97]
126587208  allantoinase-like isoform X1 [KO:K01466] [EC:3.5.2.5]
126622363  allantoinase-like [KO:K01466] [EC:3.5.2.5]
126587379  allantoate deiminase 2 [KO:K02083] [EC:3.5.3.9]
126625674  (S)-ureidoglycine aminohydrolase-like [KO:K14977] [EC:3.5.3.26]
126620035  (S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
126597016  ureidoglycolate hydrolase [KO:K18151] [EC:3.5.1.116]
126596712  urease-like [KO:K01427] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
msyl00030  Pentose phosphate pathway
msyl00220  Arginine biosynthesis
msyl00250  Alanine, aspartate and glutamate metabolism
msyl00260  Glycine, serine and threonine metabolism
msyl00340  Histidine metabolism
msyl00630  Glyoxylate and dicarboxylate metabolism
msyl00730  Thiamine metabolism
msyl00740  Riboflavin metabolism
msyl00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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