KEGG   PATHWAY: mtr00230
Entry
mtr00230                    Pathway                                
Name
Purine metabolism - Medicago truncatula (barrel medic)
Class
Metabolism; Nucleotide metabolism
Pathway map
mtr00230  Purine metabolism
mtr00230

Module
mtr_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:mtr00230]
mtr_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:mtr00230]
mtr_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:mtr00230]
mtr_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:mtr00230]
mtr_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:mtr00230]
Other DBs
GO: 0006163 0042278
Organism
Medicago truncatula (barrel medic) [GN:mtr]
Gene
11416144  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
25493698  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
11432723  nudix hydrolase 2 [KO:K26956] [EC:3.6.1.13 3.6.1.22]
25494321  nudix hydrolase 2 [KO:K26956] [EC:3.6.1.13 3.6.1.22]
25501943  nudix hydrolase 2 isoform X3 [KO:K26956] [EC:3.6.1.13 3.6.1.22]
25490725  nudix hydrolase 10 [KO:K26956] [EC:3.6.1.13 3.6.1.22]
25486266  nudix hydrolase 2 isoform X1 [KO:K26956] [EC:3.6.1.13 3.6.1.22]
11437937  nudix hydrolase 23, chloroplastic [KO:K18453] [EC:3.6.1.13 3.6.1.18]
11426348  nudix hydrolase 14, chloroplastic isoform X1 [KO:K18447] [EC:3.6.1.21]
11413693  phosphoglucomutase, cytoplasmic [KO:K01835] [EC:5.4.2.2]
11414670  phosphoglucomutase, chloroplastic [KO:K01835] [EC:5.4.2.2]
25500166  ribose-phosphate pyrophosphokinase 1 [KO:K00948] [EC:2.7.6.1]
11415474  ribose-phosphate pyrophosphokinase 1 [KO:K00948] [EC:2.7.6.1]
11438087  amidophosphoribosyltransferase, chloroplastic [KO:K00764] [EC:2.4.2.14]
11407383  LOW QUALITY PROTEIN: phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
11431305  phosphoribosylglycinamide formyltransferase, chloroplastic [KO:K00601] [EC:2.1.2.2]
25502246  probable phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial [KO:K01952] [EC:6.3.5.3]
25495271  probable phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial [KO:K01952] [EC:6.3.5.3]
11440983  phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic/mitochondrial [KO:K01933] [EC:6.3.3.1]
11405596  phosphoribosylaminoimidazole carboxylase, chloroplastic [KO:K11808] [EC:4.1.1.21]
11426009  phosphoribosylaminoimidazole-succinocarboxamide synthase, chloroplastic [KO:K01923] [EC:6.3.2.6]
11444747  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
11429175  bifunctional purine biosynthesis protein PurH isoform X1 [KO:K00602] [EC:2.1.2.3 3.5.4.10]
11437125  bifunctional purine biosynthesis protein PurH isoform X1 [KO:K00602] [EC:2.1.2.3 3.5.4.10]
25493618  adenine phosphoribosyltransferase 4 isoform X1 [KO:K00759] [EC:2.4.2.7]
11436051  adenine phosphoribosyltransferase 5 isoform X1 [KO:K00759] [EC:2.4.2.7]
11439020  adenine phosphoribosyltransferase 4 [KO:K00759] [EC:2.4.2.7]
25489954  adenine phosphoribosyltransferase 1 [KO:K00759] [EC:2.4.2.7]
11417330  5'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
11425771  5'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
11438663  uncharacterized protein LOC11438663 isoform X1 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
11439598  5'-nucleotidase SurE isoform X2 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
25485030  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
11439043  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
25500090  nucleoside diphosphate kinase 1 [KO:K00940] [EC:2.7.4.6]
11407961  nucleoside diphosphate kinase 2, chloroplastic [KO:K00940] [EC:2.7.4.6]
11413244  probable apyrase 6 [KO:K01510] [EC:3.6.1.5]
112416222  nucleoside-triphosphatase-like [KO:K14641] [EC:3.6.1.5]
25495872  apyrase 2 [KO:K14641] [EC:3.6.1.5]
11443103  apyrase 2 [KO:K14641] [EC:3.6.1.5]
11441027  nucleoside-triphosphatase [KO:K14641] [EC:3.6.1.5]
11441028  nucleoside-triphosphatase isoform X1 [KO:K14641] [EC:3.6.1.5]
11436281  nucleoside-triphosphatase [KO:K14641] [EC:3.6.1.5]
25483117  inosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
11431418  xanthine dehydrogenase 1 isoform X1 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
11419267  nudix hydrolase 25 [KO:K26955] [EC:3.6.1.17]
25502051  GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
25486064  guanylate kinase 3, chloroplastic [KO:K00942] [EC:2.7.4.8]
11433812  guanylate kinase 2 isoform X3 [KO:K00942] [EC:2.7.4.8]
11438405  ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
25488510  ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
25502786  ribonucleoside-diphosphate reductase small chain [KO:K10808] [EC:1.17.4.1]
25480771  ribonucleoside-diphosphate reductase small chain [KO:K10808] [EC:1.17.4.1]
25497818  ribonucleoside-diphosphate reductase small chain [KO:K10808] [EC:1.17.4.1]
25494012  ribonucleoside-diphosphate reductase small chain A [KO:K10808] [EC:1.17.4.1]
25483253  ribonucleoside-diphosphate reductase small chain [KO:K10808] [EC:1.17.4.1]
25480606  5'-deoxynucleotidase HDDC2 [KO:K07023] [EC:3.1.3.89]
25494275  5'-deoxynucleotidase HDDC2 [KO:K07023] [EC:3.1.3.89]
25494276  5'-deoxynucleotidase HDDC2 [KO:K07023] [EC:3.1.3.89]
11421249  probable GTP diphosphokinase RSH2, chloroplastic [KO:K00951] [EC:2.7.6.5]
25499616  putative GTP diphosphokinase RSH1, chloroplastic [KO:K00951] [EC:2.7.6.5]
11428310  probable GTP diphosphokinase CRSH, chloroplastic [KO:K00951] [EC:2.7.6.5]
11440429  adenylosuccinate synthetase 2, chloroplastic [KO:K01939] [EC:6.3.4.4]
25502814  probable AMP deaminase [KO:K01490] [EC:3.5.4.6]
112417574  AMP deaminase-like [KO:K01490] [EC:3.5.4.6]
11411569  AMP deaminase [KO:K01490] [EC:3.5.4.6]
25494427  LOW QUALITY PROTEIN: adenosine kinase 2 [KO:K00856] [EC:2.7.1.20]
11421324  adenosine kinase 2 [KO:K00856] [EC:2.7.1.20]
120576796  probable adenylate kinase 7, mitochondrial [KO:K00939] [EC:2.7.4.3]
11429873  adenylate kinase, chloroplastic [KO:K00939] [EC:2.7.4.3]
11407139  adenylate kinase 4 [KO:K00939] [EC:2.7.4.3]
25488395  adenylate kinase 5, chloroplastic [KO:K00939] [EC:2.7.4.3]
25484059  probable adenylate kinase 1, chloroplastic [KO:K00939] [EC:2.7.4.3]
11432926  adenylate kinase 1, chloroplastic [KO:K00939] [EC:2.7.4.3]
11432884  adenylate kinase isoenzyme 6 homolog [KO:K18532] [EC:2.7.4.3]
11411926  cancer-related nucleoside-triphosphatase homolog isoform X4 [KO:K06928] [EC:3.6.1.15]
11436512  venom phosphodiesterase 2 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
11439434  ectonucleotide pyrophosphatase/phosphodiesterase family member 1 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
25489167  bifunctional bis(5'-adenosyl)-triphosphatase/adenylylsulfatase FHIT [KO:K01522] [EC:3.6.1.29]
25489168  bifunctional bis(5'-adenosyl)-triphosphatase/adenylylsulfatase FHIT [KO:K01522] [EC:3.6.1.29]
25489174  bifunctional bis(5'-adenosyl)-triphosphatase/adenylylsulfatase FHIT [KO:K01522] [EC:3.6.1.29]
25495488  ATP sulfurylase 2 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
25485115  ATP sulfurylase 1, chloroplastic [KO:K13811] [EC:2.7.7.4 2.7.1.25]
25498985  adenylyl-sulfate kinase 3 [KO:K00860] [EC:2.7.1.25]
11407258  adenylyl-sulfate kinase 3-like isoform X1 [KO:K00860] [EC:2.7.1.25]
11418757  adenylyl-sulfate kinase 3 isoform X1 [KO:K00860] [EC:2.7.1.25]
25483173  uricase-2 isozyme 1 [KO:K00365] [EC:1.7.3.3]
25500241  uric acid degradation bifunctional protein TTL isoform X2 [KO:K13484] [EC:3.5.2.17 4.1.1.97]
11417093  hydroxyisourate hydrolase-like isoform X1 [KO:K19964] [EC:3.5.2.17]
11415969  hydroxyisourate hydrolase-like isoform X1 [KO:K19964] [EC:3.5.2.17]
11410877  hydroxyisourate hydrolase isoform X2 [KO:K19964] [EC:3.5.2.17]
11424917  allantoinase [KO:K01466] [EC:3.5.2.5]
25486381  allantoate deiminase 2 [KO:K02083] [EC:3.5.3.9]
25493588  (S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
11425622  ureidoglycolate hydrolase [KO:K18151] [EC:3.5.1.116]
11429087  urease isoform X1 [KO:K01427] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
mtr00030  Pentose phosphate pathway
mtr00220  Arginine biosynthesis
mtr00250  Alanine, aspartate and glutamate metabolism
mtr00260  Glycine, serine and threonine metabolism
mtr00340  Histidine metabolism
mtr00630  Glyoxylate and dicarboxylate metabolism
mtr00730  Thiamine metabolism
mtr00740  Riboflavin metabolism
mtr00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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