KEGG   PATHWAY: nsy00230
Entry
nsy00230                    Pathway                                
Name
Purine metabolism - Nicotiana sylvestris (wood tobacco)
Class
Metabolism; Nucleotide metabolism
Pathway map
nsy00230  Purine metabolism
nsy00230

Module
nsy_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:nsy00230]
nsy_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:nsy00230]
nsy_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:nsy00230]
nsy_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:nsy00230]
nsy_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:nsy00230]
Other DBs
GO: 0006163 0042278
Organism
Nicotiana sylvestris (wood tobacco) [GN:nsy]
Gene
104218770  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase-like [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
104242644  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase-like [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
104247852  nudix hydrolase 10-like [KO:K26956] [EC:3.6.1.13 3.6.1.22]
104245765  nudix hydrolase 10-like isoform X1 [KO:K26956] [EC:3.6.1.13 3.6.1.22]
104218885  nudix hydrolase 2-like isoform X1 [KO:K26956] [EC:3.6.1.13 3.6.1.22]
104229792  nudix hydrolase 2-like isoform X1 [KO:K26956] [EC:3.6.1.13 3.6.1.22]
104249700  nudix hydrolase 23, chloroplastic isoform X1 [KO:K18453] [EC:3.6.1.13 3.6.1.18]
104219747  nudix hydrolase 14, chloroplastic [KO:K18447] [EC:3.6.1.21]
104221526  phosphoglucomutase, cytoplasmic [KO:K01835] [EC:5.4.2.2]
104232687  phosphoglucomutase, chloroplastic isoform X1 [KO:K01835] [EC:5.4.2.2]
104232136  phosphoglucomutase, cytoplasmic-like isoform X1 [KO:K01835] [EC:5.4.2.2]
104230802  ribose-phosphate pyrophosphokinase 1-like isoform X1 [KO:K00948] [EC:2.7.6.1]
104222219  ribose-phosphate pyrophosphokinase 1-like [KO:K00948] [EC:2.7.6.1]
104233852  ribose-phosphate pyrophosphokinase 1 [KO:K00948] [EC:2.7.6.1]
104213697  amidophosphoribosyltransferase, chloroplastic-like [KO:K00764] [EC:2.4.2.14]
104219351  amidophosphoribosyltransferase, chloroplastic-like [KO:K00764] [EC:2.4.2.14]
104248466  phosphoribosylamine--glycine ligase-like [KO:K01945] [EC:6.3.4.13]
104237095  phosphoribosylamine--glycine ligase-like [KO:K01945] [EC:6.3.4.13]
104222607  phosphoribosylglycinamide formyltransferase, chloroplastic [KO:K00601] [EC:2.1.2.2]
104236313  probable phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial [KO:K01952] [EC:6.3.5.3]
104232976  phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic [KO:K01933] [EC:6.3.3.1]
104210402  phosphoribosylaminoimidazole carboxylase, chloroplastic isoform X1 [KO:K11808] [EC:4.1.1.21]
104227966  phosphoribosylaminoimidazole-succinocarboxamide synthase, chloroplastic [KO:K01923] [EC:6.3.2.6]
104235405  adenylosuccinate lyase-like [KO:K01756] [EC:4.3.2.2]
104224591  adenylosuccinate lyase-like [KO:K01756] [EC:4.3.2.2]
104222808  bifunctional purine biosynthesis protein purH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
104247970  adenine phosphoribosyltransferase 3-like [KO:K00759] [EC:2.4.2.7]
104235194  adenine phosphoribosyltransferase 1-like [KO:K00759] [EC:2.4.2.7]
104236039  adenine phosphoribosyltransferase 5-like [KO:K00759] [EC:2.4.2.7]
104237876  uncharacterized protein LOC104237876 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
104242507  uncharacterized protein LOC104242507 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
104231414  uncharacterized protein LOC104231414 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
104244504  uncharacterized protein LOC104244504 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
104216583  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
104240449  inosine-5'-monophosphate dehydrogenase 2-like [KO:K00088] [EC:1.1.1.205]
104229262  nucleoside diphosphate kinase 2, chloroplastic-like [KO:K00940] [EC:2.7.4.6]
104210156  nucleoside diphosphate kinase 3-like [KO:K00940] [EC:2.7.4.6]
104227481  nucleoside diphosphate kinase 2, chloroplastic [KO:K00940] [EC:2.7.4.6]
104236536  nucleoside diphosphate kinase 1 [KO:K00940] [EC:2.7.4.6]
104211008  nucleoside diphosphate kinase 1-like [KO:K00940] [EC:2.7.4.6]
104219394  nucleoside diphosphate kinase 1-like [KO:K00940] [EC:2.7.4.6]
104223629  probable apyrase 6 [KO:K01510] [EC:3.6.1.5]
104221379  apyrase 2-like [KO:K14641] [EC:3.6.1.5]
104240806  apyrase-like [KO:K14641] [EC:3.6.1.5]
104210731  apyrase 1-like [KO:K14641] [EC:3.6.1.5]
104225104  inosine triphosphate pyrophosphatase-like [KO:K01519] [EC:3.6.1.66]
104226098  inosine triphosphate pyrophosphatase-like [KO:K01519] [EC:3.6.1.66]
104224061  xanthine dehydrogenase 1-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
104250010  nudix hydrolase 25 isoform X1 [KO:K26955] [EC:3.6.1.17]
104216278  GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
104216467  guanylate kinase 2-like [KO:K00942] [EC:2.7.4.8]
104214115  guanylate kinase 2, chloroplastic/mitochondrial [KO:K00942] [EC:2.7.4.8]
104245038  ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
104246768  ribonucleoside-diphosphate reductase large subunit-like [KO:K10807] [EC:1.17.4.1]
104237583  ribonucleoside-diphosphate reductase small chain [KO:K10808] [EC:1.17.4.1]
104232223  HD domain-containing protein 2 [KO:K07023] [EC:3.1.3.89]
104222738  HD domain-containing protein 2 homolog [KO:K07023] [EC:3.1.3.89]
104240935  uncharacterized protein LOC104240935 [KO:K01514] [EC:3.6.1.11]
104231877  probable GTP diphosphokinase CRSH, chloroplastic [KO:K00951] [EC:2.7.6.5]
104248546  LOW QUALITY PROTEIN: putative GTP diphosphokinase RSH1, chloroplastic [KO:K00951] [EC:2.7.6.5]
104242241  probable GTP diphosphokinase RSH2, chloroplastic [KO:K00951] [EC:2.7.6.5]
104239548  putative GTP diphosphokinase RSH1, chloroplastic [KO:K00951] [EC:2.7.6.5]
104231275  phytosulfokine receptor 1 [KO:K27625] [EC:2.7.11.1 4.6.1.2]
104249937  adenylosuccinate synthetase, chloroplastic [KO:K01939] [EC:6.3.4.4]
104233451  adenylosuccinate synthetase, chloroplastic-like [KO:K01939] [EC:6.3.4.4]
104210522  AMP deaminase [KO:K01490] [EC:3.5.4.6]
104222754  probable AMP deaminase [KO:K01490] [EC:3.5.4.6]
104240846  adenosine kinase 2-like [KO:K00856] [EC:2.7.1.20]
104230519  adenosine kinase 2 [KO:K00856] [EC:2.7.1.20]
104223285  adenylate kinase 4 [KO:K00939] [EC:2.7.4.3]
104225594  adenylate kinase 5, chloroplastic [KO:K00939] [EC:2.7.4.3]
104231798  adenylate kinase 4 [KO:K00939] [EC:2.7.4.3]
104240827  adenylate kinase 4-like [KO:K00939] [EC:2.7.4.3]
104211400  adenylate kinase, chloroplastic isoform X1 [KO:K00939] [EC:2.7.4.3]
104224313  adenylate kinase [KO:K00939] [EC:2.7.4.3]
104239348  probable adenylate kinase 7, mitochondrial [KO:K00939] [EC:2.7.4.3]
104239971  probable adenylate kinase 6, chloroplastic [KO:K00939] [EC:2.7.4.3]
104231887  adenylate kinase isoenzyme 6 homolog [KO:K18532] [EC:2.7.4.3]
104240840  cancer-related nucleoside-triphosphatase [KO:K06928] [EC:3.6.1.15]
104233758  ectonucleotide pyrophosphatase/phosphodiesterase family member 1-like [KO:K01513] [EC:3.1.4.1 3.6.1.9]
104243647  bis(5'-adenosyl)-triphosphatase [KO:K01522] [EC:3.6.1.29]
104227790  ATP sulfurylase 1, chloroplastic-like [KO:K13811] [EC:2.7.7.4 2.7.1.25]
104234839  ATP sulfurylase 1, chloroplastic-like [KO:K13811] [EC:2.7.7.4 2.7.1.25]
104213769  ATP sulfurylase 2 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
104234483  adenylyl-sulfate kinase 3-like [KO:K00860] [EC:2.7.1.25]
104235913  adenylyl-sulfate kinase 3-like [KO:K00860] [EC:2.7.1.25]
104243758  adenylyl-sulfate kinase 3-like [KO:K00860] [EC:2.7.1.25]
104215352  adenylyl-sulfate kinase 3-like [KO:K00860] [EC:2.7.1.25]
104211356  uricase-2 isozyme 1 [KO:K00365] [EC:1.7.3.3]
104241157  uric acid degradation bifunctional protein TTL isoform X1 [KO:K13484] [EC:3.5.2.17 4.1.1.97]
104214902  allantoinase isoform X1 [KO:K01466] [EC:3.5.2.5]
104224519  allantoate deiminase [KO:K02083] [EC:3.5.3.9]
104224652  (S)-ureidoglycine aminohydrolase isoform X1 [KO:K14977] [EC:3.5.3.26]
104249923  ureidoglycolate hydrolase [KO:K18151] [EC:3.5.1.116]
104229192  urease [KO:K01427] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
nsy00030  Pentose phosphate pathway
nsy00220  Arginine biosynthesis
nsy00250  Alanine, aspartate and glutamate metabolism
nsy00260  Glycine, serine and threonine metabolism
nsy00340  Histidine metabolism
nsy00630  Glyoxylate and dicarboxylate metabolism
nsy00730  Thiamine metabolism
nsy00740  Riboflavin metabolism
nsy00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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