KEGG   PATHWAY: pvir00053
Entry
pvir00053                   Pathway                                
Name
Ascorbate and aldarate metabolism - Panicum virgatum (switchgrass)
Class
Metabolism; Carbohydrate metabolism
Pathway map
pvir00053  Ascorbate and aldarate metabolism
pvir00053

Module
pvir_M00114  Ascorbate biosynthesis, plants, fructose-6P => ascorbate [PATH:pvir00053]
Other DBs
GO: 0019852 0019577 0019572
Organism
Panicum virgatum (switchgrass) [GN:pvir]
Gene
120688499  UDP-glucose 6-dehydrogenase 4-like [KO:K00012] [EC:1.1.1.22]
120690048  UDP-glucose 6-dehydrogenase 5-like [KO:K00012] [EC:1.1.1.22]
120646890  UDP-glucose 6-dehydrogenase 4-like [KO:K00012] [EC:1.1.1.22]
120678463  UDP-glucose 6-dehydrogenase 4 [KO:K00012] [EC:1.1.1.22]
120692779  UDP-glucose 6-dehydrogenase 2 [KO:K00012] [EC:1.1.1.22]
120649708  UDP-glucose 6-dehydrogenase 5-like [KO:K00012] [EC:1.1.1.22]
120704388  UDP-sugar pyrophosphorylase [KO:K12447] [EC:2.7.7.64]
120668692  UDP-sugar pyrophosphorylase-like [KO:K12447] [EC:2.7.7.64]
120673759  glucuronokinase 1-like isoform X1 [KO:K16190] [EC:2.7.1.43]
120706703  glucuronokinase 1-like isoform X1 [KO:K16190] [EC:2.7.1.43]
120670417  probable inositol oxygenase [KO:K00469] [EC:1.13.99.1]
120704861  probable inositol oxygenase [KO:K00469] [EC:1.13.99.1]
120672526  NADPH-dependent aldo-keto reductase, chloroplastic-like isoform X1 [KO:K00002] [EC:1.1.1.2]
120673108  NADPH-dependent aldo-keto reductase, chloroplastic-like isoform X1 [KO:K00002] [EC:1.1.1.2]
120673109  aldo-keto reductase family 4 member C10-like [KO:K00002] [EC:1.1.1.2]
120708649  aldo-keto reductase family 4 member C10-like [KO:K00002] [EC:1.1.1.2]
120708651  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
120708653  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
120665272  aldo-keto reductase family 4 member C10-like isoform X1 [KO:K00002] [EC:1.1.1.2]
120665273  aldo-keto reductase family 4 member C10-like [KO:K00002] [EC:1.1.1.2]
120667680  aldo-keto reductase family 1 member C23-like protein [KO:K00002] [EC:1.1.1.2]
120698377  LOW QUALITY PROTEIN: aldose reductase [KO:K00002] [EC:1.1.1.2]
120698478  aldo-keto reductase family 4 member C10-like [KO:K00002] [EC:1.1.1.2]
120698479  aldo-keto reductase family 4 member C10-like [KO:K00002] [EC:1.1.1.2]
120655450  L-gulonolactone oxidase 3-like [KO:K00103] [EC:1.1.3.8]
120648401  L-gulonolactone oxidase 2-like [KO:K00103] [EC:1.1.3.8]
120707520  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
120678572  L-gulonolactone oxidase 2-like [KO:K00103] [EC:1.1.3.8]
120678668  L-gulonolactone oxidase 2-like [KO:K00103] [EC:1.1.3.8]
120693536  L-gulonolactone oxidase 2-like [KO:K00103] [EC:1.1.3.8]
120679522  L-gulonolactone oxidase 5-like [KO:K00103] [EC:1.1.3.8]
120711194  probable L-gulonolactone oxidase 4 [KO:K00103] [EC:1.1.3.8]
120712184  L-gulonolactone oxidase 2-like [KO:K00103] [EC:1.1.3.8]
120712304  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
120667685  LOW QUALITY PROTEIN: probable truncated L-gulonolactone oxidase 7, mitochondrial [KO:K00103] [EC:1.1.3.8]
120698286  L-gulonolactone oxidase 3-like [KO:K00103] [EC:1.1.3.8]
120685784  GDP-mannose 3,5-epimerase 2-like [KO:K10046] [EC:5.1.3.18 5.1.3.-]
120644778  GDP-mannose 3,5-epimerase 2 [KO:K10046] [EC:5.1.3.18 5.1.3.-]
120690158  GDP-mannose 3,5-epimerase 1 [KO:K10046] [EC:5.1.3.18 5.1.3.-]
120678581  GDP-mannose 3,5-epimerase 1-like [KO:K10046] [EC:5.1.3.18 5.1.3.-]
120651043  GDP-mannose 3,5-epimerase 1-like [KO:K10046] [EC:5.1.3.18 5.1.3.-]
120711419  GDP-mannose 3,5-epimerase 1-like [KO:K10046] [EC:5.1.3.18 5.1.3.-]
120700116  GDP-L-galactose phosphorylase 1-like [KO:K14190] [EC:2.7.7.69]
120675751  GDP-L-galactose phosphorylase 1-like isoform X1 [KO:K14190] [EC:2.7.7.69]
120696906  GDP-L-galactose phosphorylase 2-like [KO:K14190] [EC:2.7.7.69]
120666608  GDP-L-galactose phosphorylase 2-like [KO:K14190] [EC:2.7.7.69]
120666912  GDP-L-galactose phosphorylase 1-like [KO:K14190] [EC:2.7.7.69]
120691757  inositol monophosphatase 3-like [KO:K10047] [EC:3.1.3.25 3.1.3.93]
120650449  inositol monophosphatase 3-like [KO:K10047] [EC:3.1.3.25 3.1.3.93]
120706421  bifunctional phosphatase IMPL2, chloroplastic-like [KO:K18649] [EC:3.1.3.25 3.1.3.93 3.1.3.15]
120699475  L-galactose dehydrogenase-like [KO:K17744] [EC:1.1.1.316]
120666191  L-galactose dehydrogenase-like [KO:K17744] [EC:1.1.1.316]
120684672  L-galactono-1,4-lactone dehydrogenase 1, mitochondrial [KO:K00225] [EC:1.3.2.3]
120643526  L-galactono-1,4-lactone dehydrogenase 2, mitochondrial-like isoform X1 [KO:K00225] [EC:1.3.2.3]
120702857  UDP-glucuronate 4-epimerase 1-like [KO:K08679] [EC:5.1.3.6]
120657444  UDP-glucuronate 4-epimerase 1-like [KO:K08679] [EC:5.1.3.6]
120644595  UDP-glucuronate 4-epimerase 1-like [KO:K08679] [EC:5.1.3.6]
120691086  UDP-glucuronate 4-epimerase 2-like [KO:K08679] [EC:5.1.3.6]
120661158  UDP-glucuronate 4-epimerase 6-like [KO:K08679] [EC:5.1.3.6]
120679954  UDP-glucuronate 4-epimerase 6-like [KO:K08679] [EC:5.1.3.6]
120680182  UDP-glucuronate 4-epimerase 6-like [KO:K08679] [EC:5.1.3.6]
120680241  UDP-glucuronate 4-epimerase 6-like [KO:K08679] [EC:5.1.3.6]
120695777  UDP-glucuronate 4-epimerase 6-like [KO:K08679] [EC:5.1.3.6]
120653003  UDP-glucuronate 4-epimerase 2-like [KO:K08679] [EC:5.1.3.6]
120712937  UDP-glucuronate 4-epimerase 6-like [KO:K08679] [EC:5.1.3.6]
120668903  UDP-glucuronate 4-epimerase 1-like [KO:K08679] [EC:5.1.3.6]
120671225  monodehydroascorbate reductase 3, cytosolic-like [KO:K08232] [EC:1.6.5.4]
120656965  monodehydroascorbate reductase 2, peroxisomal [KO:K08232] [EC:1.6.5.4]
120656966  monodehydroascorbate reductase 1, peroxisomal-like [KO:K08232] [EC:1.6.5.4]
120659993  monodehydroascorbate reductase 3, cytosolic [KO:K08232] [EC:1.6.5.4]
120677744  monodehydroascorbate reductase 4, cytosolic [KO:K08232] [EC:1.6.5.4]
120678334  monodehydroascorbate reductase 5, chlorplastic [KO:K08232] [EC:1.6.5.4]
120649632  monodehydroascorbate reductase 1, peroxisomal-like isoform X1 [KO:K08232] [EC:1.6.5.4]
120711394  monodehydroascorbate reductase 5, chlorplastic-like [KO:K08232] [EC:1.6.5.4]
120713832  monodehydroascorbate reductase 4, cytosolic-like [KO:K08232] [EC:1.6.5.4]
120640175  probable L-ascorbate peroxidase 3, peroxisomal [KO:K00434] [EC:1.11.1.11]
120640948  probable L-ascorbate peroxidase 8, chloroplastic isoform X1 [KO:K00434] [EC:1.11.1.11]
120641028  probable L-ascorbate peroxidase 7, chloroplastic [KO:K00434] [EC:1.11.1.11]
120687989  L-ascorbate peroxidase 1, cytosolic-like [KO:K00434] [EC:1.11.1.11]
120662269  L-ascorbate peroxidase 2, cytosolic [KO:K00434] [EC:1.11.1.11]
120663742  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial [KO:K00434] [EC:1.11.1.11]
120678459  putative L-ascorbate peroxidase 6 isoform X1 [KO:K00434] [EC:1.11.1.11]
120678528  probable L-ascorbate peroxidase 4, peroxisomal [KO:K00434] [EC:1.11.1.11]
120696865  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial [KO:K00434] [EC:1.11.1.11]
120682240  probable L-ascorbate peroxidase 8, chloroplastic [KO:K00434] [EC:1.11.1.11]
120682370  probable L-ascorbate peroxidase 7, chloroplastic [KO:K00434] [EC:1.11.1.11]
120652750  L-ascorbate peroxidase 1, cytosolic [KO:K00434] [EC:1.11.1.11]
120712855  putative L-ascorbate peroxidase 6 isoform X1 [KO:K00434] [EC:1.11.1.11]
120683430  probable L-ascorbate peroxidase 3, peroxisomal [KO:K00434] [EC:1.11.1.11]
120713778  probable L-ascorbate peroxidase 4, peroxisomal [KO:K00434] [EC:1.11.1.11]
120670112  probable glutathione S-transferase DHAR2, chloroplastic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
120703055  probable glutathione S-transferase DHAR2, chloroplastic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
120664052  probable glutathione S-transferase DHAR1, cytosolic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
120697269  probable glutathione S-transferase DHAR1, cytosolic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
120667827  probable glutathione S-transferase DHAR1, cytosolic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
120670572  L-ascorbate oxidase-like [KO:K00423] [EC:1.10.3.3]
120670590  L-ascorbate oxidase-like [KO:K00423] [EC:1.10.3.3]
120703719  L-ascorbate oxidase-like [KO:K00423] [EC:1.10.3.3]
120675521  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
120710778  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
120667429  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
120698327  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
120640655  benzaldehyde dehydrogenase, mitochondrial-like isoform X1 [KO:K00128] [EC:1.2.1.3]
120685688  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
120641383  aldehyde dehydrogenase family 3 member F1-like [KO:K00128] [EC:1.2.1.3]
120656625  aldehyde dehydrogenase family 3 member F1-like [KO:K00128] [EC:1.2.1.3]
120657119  benzaldehyde dehydrogenase, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
120703420  aldehyde dehydrogenase family 2 member B7, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
120643849  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
120696860  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
120710971  aldehyde dehydrogenase family 3 member F1-like isoform X1 [KO:K00128] [EC:1.2.1.3]
120682871  aldehyde dehydrogenase family 3 member F1-like [KO:K00128] [EC:1.2.1.3]
120669652  benzaldehyde dehydrogenase, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
120660777  aldehyde dehydrogenase family 7 member A1-like [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
120679927  aldehyde dehydrogenase family 7 member A1-like [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
Compound
C00022  Pyruvate
C00026  2-Oxoglutarate
C00029  UDP-glucose
C00072  Ascorbate
C00096  GDP-mannose
C00137  myo-Inositol
C00167  UDP-glucuronate
C00191  D-Glucuronate
C00216  D-Arabinose
C00231  D-Xylulose 5-phosphate
C00259  L-Arabinose
C00333  D-Galacturonate
C00433  2,5-Dioxopentanoate
C00545  L-Arabinonate
C00558  D-Tagaturonate
C00617  UDP-D-galacturonate
C00618  3-Dehydro-L-gulonate
C00652  D-Arabinono-1,4-lactone
C00679  5-Dehydro-4-deoxy-D-glucarate
C00684  2-Dehydro-3-deoxy-L-arabinonate
C00800  L-Gulonate
C00818  D-Glucarate
C00878  D-Arabinonate
C00879  D-Galactarate
C01040  L-Gulono-1,4-lactone
C01041  Monodehydroascorbate
C01101  L-Ribulose 5-phosphate
C01114  L-Arabinono-1,4-lactone
C01115  L-Galactono-1,4-lactone
C01146  2-Hydroxy-3-oxopropanoate
C01620  Threonate
C01825  L-Galactose
C02280  GDP-L-galactose
C02670  D-Glucuronolactone
C03033  beta-D-Glucuronoside
C03064  3-Dehydro-L-threonate
C03289  L-xylo-Hexulonolactone
C03291  L-Xylulose 5-phosphate
C03826  2-Dehydro-3-deoxy-D-xylonate
C03921  2-Dehydro-3-deoxy-D-glucarate
C04037  1-Phospho-alpha-D-galacturonate
C04575  (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385  D-Glucuronate 1-phosphate
C05411  L-Xylonate
C05412  L-Lyxonate
C05422  Dehydroascorbate
C06316  Dehydro-D-arabinono-1,4-lactone
C14899  3-Dehydro-L-gulonate 6-phosphate
C15923  L-Gulose
C15924  L-Gulose 1-phosphate
C15925  GDP-L-gulose
C15926  beta-L-Galactose 1-phosphate
C15930  L-Galactonate
C16186  L-Ascorbate 6-phosphate
C20889  D-Galactaro-1,5-lactone
C20896  D-Galactaro-1,4-lactone
C21955  L-Galactono-1,5-lactone
Reference
PMID:17222174
  Authors
Linster CL, Van Schaftingen E
  Title
Vitamin C. Biosynthesis, recycling and degradation in mammals.
  Journal
FEBS J 274:1-22 (2007)
DOI:10.1111/j.1742-4658.2006.05607.x
Reference
PMID:15564123
  Authors
Valpuesta V, Botella MA.
  Title
Biosynthesis of L-ascorbic acid in plants: new pathways for an old antioxidant.
  Journal
Trends Plant Sci 9:573-7 (2004)
DOI:10.1016/j.tplants.2004.10.002
Reference
PMID:10517845
  Authors
Davey MW, Gilot C, Persiau G, Ostergaard J, Han Y, Bauw GC, Van Montagu MC.
  Title
Ascorbate biosynthesis in Arabidopsis cell suspension culture.
  Journal
Plant Physiol 121:535-43 (1999)
DOI:10.1104/pp.121.2.535
Reference
PMID:16595667
  Authors
Conklin PL, Gatzek S, Wheeler GL, Dowdle J, Raymond MJ, Rolinski S, Isupov M, Littlechild JA, Smirnoff N.
  Title
Arabidopsis thaliana VTC4 encodes L-galactose-1-P phosphatase, a plant ascorbic acid biosynthetic enzyme.
  Journal
J Biol Chem 281:15662-70 (2006)
DOI:10.1074/jbc.M601409200
Reference
PMID:17462988
  Authors
Linster CL, Gomez TA, Christensen KC, Adler LN, Young BD, Brenner C, Clarke SG.
  Title
Arabidopsis VTC2 Encodes a GDP-L-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants.
  Journal
J Biol Chem 282:18879-85 (2007)
DOI:10.1074/jbc.M702094200
Reference
PMID:14996803
  Authors
Campos E, Baldoma L, Aguilar J, Badia J.
  Title
Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in LaAscorbate dissimilation in Escherichia coli.
  Journal
J Bacteriol 186:1720-8 (2004)
DOI:10.1128/JB.186.6.1720-1728.2004
Reference
PMID:12644495
  Authors
Zhang Z, Aboulwafa M, Smith MH, Saier MH Jr.
  Title
The ascorbate transporter of Escherichia coli.
  Journal
J Bacteriol 185:2243-50 (2003)
DOI:10.1128/JB.185.7.2243-2250.2003
Related
pathway
pvir00020  Citrate cycle (TCA cycle)
pvir00040  Pentose and glucuronate interconversions
pvir00051  Fructose and mannose metabolism
pvir00520  Amino sugar and nucleotide sugar metabolism
pvir00630  Glyoxylate and dicarboxylate metabolism
KO pathway
ko00053   
LinkDB

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