KEGG   PATHWAY: smil00230
Entry
smil00230                   Pathway                                
Name
Purine metabolism - Salvia miltiorrhiza (redroot sage)
Class
Metabolism; Nucleotide metabolism
Pathway map
smil00230  Purine metabolism
smil00230

Module
smil_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:smil00230]
smil_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:smil00230]
smil_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:smil00230]
smil_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:smil00230]
Other DBs
GO: 0006163 0042278
Organism
Salvia miltiorrhiza (redroot sage) [GN:smil]
Gene
131019671  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase-like [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
131019672  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase-like [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
131005113  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase-like [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
130986172  nudix hydrolase 2-like isoform X1 [KO:K26956] [EC:3.6.1.13 3.6.1.22]
130988800  nudix hydrolase 23, chloroplastic isoform X1 [KO:K18453] [EC:3.6.1.13 3.6.1.18]
131026367  nudix hydrolase 14, chloroplastic isoform X1 [KO:K18447] [EC:3.6.1.21]
130993542  phosphoglucomutase, chloroplastic [KO:K01835] [EC:5.4.2.2]
130995931  phosphoglucomutase, cytoplasmic [KO:K01835] [EC:5.4.2.2]
130992770  ribose-phosphate pyrophosphokinase 1-like isoform X1 [KO:K00948] [EC:2.7.6.1]
131022158  ribose-phosphate pyrophosphokinase 1 isoform X1 [KO:K00948] [EC:2.7.6.1]
131001022  amidophosphoribosyltransferase, chloroplastic-like [KO:K00764] [EC:2.4.2.14]
131005590  amidophosphoribosyltransferase, chloroplastic-like [KO:K00764] [EC:2.4.2.14]
130985158  phosphoribosylamine--glycine ligase-like [KO:K01945] [EC:6.3.4.13]
131014756  phosphoribosylamine--glycine ligase-like [KO:K01945] [EC:6.3.4.13]
130985855  phosphoribosylglycinamide formyltransferase, chloroplastic [KO:K00601] [EC:2.1.2.2]
131005860  probable phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial [KO:K01952] [EC:6.3.5.3]
131005861  probable phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial [KO:K01952] [EC:6.3.5.3]
130985132  phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic/mitochondrial-like isoform X1 [KO:K01933] [EC:6.3.3.1]
130992626  phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic/mitochondrial-like [KO:K01933] [EC:6.3.3.1]
130992627  phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic/mitochondrial-like [KO:K01933] [EC:6.3.3.1]
130985195  phosphoribosylaminoimidazole carboxylase, chloroplastic [KO:K11808] [EC:4.1.1.21]
131026247  phosphoribosylaminoimidazole-succinocarboxamide synthase, chloroplastic [KO:K01923] [EC:6.3.2.6]
130994661  uncharacterized protein LOC130994661 [KO:K01756] [EC:4.3.2.2]
131025582  uncharacterized protein LOC131025582 [KO:K01756] [EC:4.3.2.2]
131000344  uncharacterized protein LOC131000344 isoform X1 [KO:K00602] [EC:2.1.2.3 3.5.4.10]
130992271  adenine phosphoribosyltransferase 5-like [KO:K00759] [EC:2.4.2.7]
131025253  adenine phosphoribosyltransferase 4-like isoform X1 [KO:K00759] [EC:2.4.2.7]
130995276  adenine phosphoribosyltransferase 5-like [KO:K00759] [EC:2.4.2.7]
130998626  adenine phosphoribosyltransferase 1-like isoform X1 [KO:K00759] [EC:2.4.2.7]
131004268  adenine phosphoribosyltransferase 5-like isoform X1 [KO:K00759] [EC:2.4.2.7]
130993027  LOW QUALITY PROTEIN: uncharacterized protein LOC130993027 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
131001064  uncharacterized protein LOC131001064 isoform X1 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
130991338  uncharacterized protein LOC130991338 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
130991480  uncharacterized protein LOC130991480 [KO:K03787] [EC:3.1.3.5 3.1.3.6]
130994881  uncharacterized protein LOC130994881 [KO:K00760] [EC:2.4.2.8]
131024512  nucleoside diphosphate kinase 3-like [KO:K00940] [EC:2.7.4.6]
131017803  nucleoside diphosphate kinase 3-like [KO:K00940] [EC:2.7.4.6]
131020588  nucleoside diphosphate kinase 1-like [KO:K00940] [EC:2.7.4.6]
131021598  nucleoside diphosphate kinase 2, chloroplastic [KO:K00940] [EC:2.7.4.6]
131022810  nucleoside diphosphate kinase 1 [KO:K00940] [EC:2.7.4.6]
130995795  probable apyrase 6 [KO:K01510] [EC:3.6.1.5]
130992591  apyrase 2-like isoform X1 [KO:K14641] [EC:3.6.1.5]
131026219  apyrase-like [KO:K14641] [EC:3.6.1.5]
131026221  apyrase-like [KO:K14641] [EC:3.6.1.5]
131001272  inosine triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
131015788  xanthine dehydrogenase 2-like isoform X1 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
130986497  nudix hydrolase 25 [KO:K26955] [EC:3.6.1.17]
131015673  uncharacterized protein LOC131015673 [KO:K01951] [EC:6.3.5.2]
130990136  guanylate kinase 2 [KO:K00942] [EC:2.7.4.8]
130991573  guanylate kinase 2, chloroplastic/mitochondrial [KO:K00942] [EC:2.7.4.8]
130993720  ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
131020935  ribonucleoside-diphosphate reductase small chain A [KO:K10808] [EC:1.17.4.1]
131024432  uncharacterized protein LOC131024432 isoform X1 [KO:K07023] [EC:3.1.3.89]
131024442  uncharacterized protein LOC131024442 isoform X1 [KO:K07023] [EC:3.1.3.89]
131005025  uncharacterized protein LOC131005025 isoform X1 [KO:K07023] [EC:3.1.3.89]
131026358  uncharacterized protein LOC131026358 [KO:K01514] [EC:3.6.1.11]
130995385  putative GTP diphosphokinase RSH1, chloroplastic isoform X1 [KO:K00951] [EC:2.7.6.5]
131013110  probable GTP diphosphokinase RSH2, chloroplastic [KO:K00951] [EC:2.7.6.5]
131004094  probable GTP diphosphokinase RSH2, chloroplastic [KO:K00951] [EC:2.7.6.5]
131021612  probable GTP diphosphokinase CRSH, chloroplastic [KO:K00951] [EC:2.7.6.5]
131021640  probable GTP diphosphokinase CRSH, chloroplastic [KO:K00951] [EC:2.7.6.5]
130996294  phytosulfokine receptor 1 [KO:K27625] [EC:2.7.11.1 4.6.1.2]
130990132  adenylosuccinate synthetase 1, chloroplastic [KO:K01939] [EC:6.3.4.4]
130995712  AMP deaminase-like isoform X1 [KO:K01490] [EC:3.5.4.6]
131016530  AMP deaminase [KO:K01490] [EC:3.5.4.6]
130997764  adenosine kinase 2-like [KO:K00856] [EC:2.7.1.20]
131020539  adenosine kinase 2 [KO:K00856] [EC:2.7.1.20]
131010186  adenylate kinase, chloroplastic [KO:K00939] [EC:2.7.4.3]
131014936  probable adenylate kinase 6, chloroplastic [KO:K00939] [EC:2.7.4.3]
131016704  adenylate kinase [KO:K00939] [EC:2.7.4.3]
130987431  probable adenylate kinase 7, mitochondrial [KO:K00939] [EC:2.7.4.3]
130987546  adenylate kinase 5, chloroplastic isoform X1 [KO:K00939] [EC:2.7.4.3]
130987811  adenylate kinase 4 [KO:K00939] [EC:2.7.4.3]
131003517  adenylate kinase 4 isoform X1 [KO:K00939] [EC:2.7.4.3]
131000690  adenylate kinase isoenzyme 6 homolog [KO:K18532] [EC:2.7.4.3]
131023791  uncharacterized protein LOC131023791 isoform X1 [KO:K06928] [EC:3.6.1.15]
130986415  uncharacterized protein LOC130986415 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
131004899  uncharacterized protein LOC131004899 [KO:K01513] [EC:3.1.4.1 3.6.1.9]
130992172  bifunctional bis(5'-adenosyl)-triphosphatase/adenylylsulfatase FHIT isoform X1 [KO:K01522] [EC:3.6.1.29]
130995560  ATP sulfurylase 2 isoform X1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
131001117  ATP sulfurylase 1, chloroplastic-like isoform X1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
130991365  ATP sulfurylase 1, chloroplastic-like [KO:K13811] [EC:2.7.7.4 2.7.1.25]
131000267  adenylyl-sulfate kinase 3-like isoform X1 [KO:K00860] [EC:2.7.1.25]
131021557  adenylyl-sulfate kinase 3-like isoform X1 [KO:K00860] [EC:2.7.1.25]
130997402  uricase-2 isozyme 1 [KO:K00365] [EC:1.7.3.3]
131015862  uric acid degradation bifunctional protein TTL-like isoform X1 [KO:K13484] [EC:3.5.2.17 4.1.1.97]
131015874  uric acid degradation bifunctional protein TTL-like isoform X1 [KO:K13484] [EC:3.5.2.17 4.1.1.97]
130985524  allantoinase [KO:K01466] [EC:3.5.2.5]
131026249  allantoate deiminase 2 [KO:K02083] [EC:3.5.3.9]
131009545  (S)-ureidoglycine aminohydrolase isoform X1 [KO:K14977] [EC:3.5.3.26]
131001092  ureidoglycolate hydrolase [KO:K18151] [EC:3.5.1.116]
130995592  urease [KO:K01427] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
smil00030  Pentose phosphate pathway
smil00220  Arginine biosynthesis
smil00250  Alanine, aspartate and glutamate metabolism
smil00260  Glycine, serine and threonine metabolism
smil00340  Histidine metabolism
smil00630  Glyoxylate and dicarboxylate metabolism
smil00730  Thiamine metabolism
smil00740  Riboflavin metabolism
smil00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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