KEGG   PATHWAY: tcf00230
Entry
tcf00230                    Pathway                                
Name
Purine metabolism - Tigriopus californicus (tidepool copepod)
Class
Metabolism; Nucleotide metabolism
Pathway map
tcf00230  Purine metabolism
tcf00230

Module
tcf_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:tcf00230]
tcf_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:tcf00230]
tcf_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:tcf00230]
tcf_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:tcf00230]
tcf_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:tcf00230]
tcf_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:tcf00230]
Other DBs
GO: 0006163 0042278
Organism
Tigriopus californicus (tidepool copepod) [GN:tcf]
Gene
131884173  ADP-ribose pyrophosphatase, mitochondrial-like [KO:K13988] [EC:3.6.1.13]
131877162  phosphoglucomutase-1-like [KO:K01835] [EC:5.4.2.2]
131888156  phosphopentomutase-like [KO:K15779] [EC:5.4.2.2 5.4.2.7]
131880874  ribose-phosphate pyrophosphokinase 2-like [KO:K00948] [EC:2.7.6.1]
131878396  ribose-phosphate pyrophosphokinase 1 isoform X1 [KO:K00948] [EC:2.7.6.1]
131886275  adenylosuccinate lyase-like [KO:K01756] [EC:4.3.2.2]
131892752  adenine phosphoribosyltransferase-like [KO:K00759] [EC:2.4.2.7]
131893493  cytosolic purine 5'-nucleotidase-like isoform X1 [KO:K01081] [EC:3.1.3.5]
131885206  uncharacterized protein LOC131885206 [KO:K01081] [EC:3.1.3.5]
131892816  protein 5NUC-like [KO:K19970] [EC:3.1.3.5]
131893365  protein 5NUC-like [KO:K19970] [EC:3.1.3.5]
131888312  snake venom 5'-nucleotidase-like [KO:K19970] [EC:3.1.3.5]
131885169  purine nucleoside phosphorylase-like isoform X1 [KO:K03783] [EC:2.4.2.1]
131888489  purine nucleoside phosphorylase-like [KO:K03783] [EC:2.4.2.1]
131892175  hypoxanthine-guanine phosphoribosyltransferase-like [KO:K00760] [EC:2.4.2.8]
131883477  hypoxanthine-guanine phosphoribosyltransferase-like [KO:K00760] [EC:2.4.2.8]
131891493  inosine-5'-monophosphate dehydrogenase 2-like [KO:K00088] [EC:1.1.1.205]
131890644  nucleoside diphosphate kinase 6-like [KO:K00940] [EC:2.7.4.6]
131878550  nucleoside diphosphate kinase B-like [KO:K00940] [EC:2.7.4.6]
131878956  nucleoside diphosphate kinase 7-like isoform X1 [KO:K00940] [EC:2.7.4.6]
131893176  ectonucleoside triphosphate diphosphohydrolase 1-like [KO:K01510] [EC:3.6.1.5]
131879425  ectonucleoside triphosphate diphosphohydrolase 1-like [KO:K01510] [EC:3.6.1.5]
131879484  ectonucleoside triphosphate diphosphohydrolase 1-like [KO:K01510] [EC:3.6.1.5]
131879634  ectonucleoside triphosphate diphosphohydrolase 3-like [KO:K01510] [EC:3.6.1.5]
131877346  soluble calcium-activated nucleotidase 1-like [KO:K12304] [EC:3.6.1.6]
131881088  ectonucleoside triphosphate diphosphohydrolase 7-like isoform X1 [KO:K12305] [EC:3.6.1.6]
131885393  ectonucleoside triphosphate diphosphohydrolase 5-like [KO:K01511] [EC:3.6.1.6]
131888956  ectonucleoside triphosphate diphosphohydrolase 5-like [KO:K01511] [EC:3.6.1.6]
131880538  inosine triphosphate pyrophosphatase-like [KO:K01519] [EC:3.6.1.66]
131881123  uncharacterized protein LOC131881123 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
131881124  uncharacterized protein LOC131881124 isoform X1 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
131881125  uncharacterized protein LOC131881125 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
131883888  xanthine dehydrogenase/oxidase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
131884106  xanthine dehydrogenase/oxidase-like [KO:K00106] [EC:1.17.1.4 1.17.3.2]
131882655  GMP synthase [glutamine-hydrolyzing]-like [KO:K01951] [EC:6.3.5.2]
131885442  GMP reductase 2-like [KO:K00364] [EC:1.7.1.7]
131892776  guanine deaminase-like [KO:K01487] [EC:3.5.4.3]
131881926  guanylate kinase-like [KO:K00942] [EC:2.7.4.8]
131877841  guanylate kinase-like [KO:K00942] [EC:2.7.4.8]
131893135  ribonucleoside-diphosphate reductase large subunit-like [KO:K10807] [EC:1.17.4.1]
131880718  ribonucleoside-diphosphate reductase subunit M2 B-like [KO:K10808] [EC:1.17.4.1]
131889936  deoxynucleoside kinase-like [KO:K05961] [EC:2.7.1.145]
131882528  deoxynucleoside kinase-like isoform X1 [KO:K05961] [EC:2.7.1.145]
131885170  deoxynucleoside kinase-like [KO:K05961] [EC:2.7.1.145]
131878958  deoxynucleoside kinase-like [KO:K05961] [EC:2.7.1.145]
131879683  deoxynucleoside kinase-like [KO:K05961] [EC:2.7.1.145]
131882539  guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1-like [KO:K21138] [EC:3.1.7.2]
131889184  exopolyphosphatase PRUNE1-like [KO:K01514] [EC:3.6.1.11]
131882946  adenylate cyclase type 2-like [KO:K08042] [EC:4.6.1.1]
131876822  adenylate cyclase type 2-like [KO:K08042] [EC:4.6.1.1]
131893046  soluble guanylate cyclase 88E-like isoform X1 [KO:K12319] [EC:4.6.1.2]
131882228  soluble guanylate cyclase 88E-like [KO:K12319] [EC:4.6.1.2]
131882517  soluble guanylate cyclase 88E-like isoform X1 [KO:K12319] [EC:4.6.1.2]
131892768  atrial natriuretic peptide receptor 1-like [KO:K12323] [EC:4.6.1.2]
131891810  receptor-type guanylate cyclase Gyc76C-like isoform X1 [KO:K01769] [EC:4.6.1.2]
131885275  dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B-like isoform X1 [KO:K13755] [EC:3.1.4.17]
131877915  cGMP-dependent 3',5'-cyclic phosphodiesterase-like isoform X1 [KO:K18283] [EC:3.1.4.17]
131877104  dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11-like [KO:K13762] [EC:3.1.4.35]
131888889  cGMP-specific 3',5'-cyclic phosphodiesterase-like [KO:K13762] [EC:3.1.4.35]
131886960  retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta-like [KO:K13758]
131880232  cGMP-specific 3',5'-cyclic phosphodiesterase-like isoform X1 [KO:K13763] [EC:3.1.4.35]
131890625  high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A-like isoform X1 [KO:K13761] [EC:3.1.4.35]
131885892  probable 3',5'-cyclic phosphodiesterase pde-5 isoform X1 [KO:K18438] [EC:3.1.4.17 3.1.4.35]
131891211  adenylosuccinate synthetase-like [KO:K01939] [EC:6.3.4.4]
131882967  AMP deaminase 2-like isoform X1 [KO:K01490] [EC:3.5.4.6]
131883152  uncharacterized protein LOC131883152 [KO:K00856] [EC:2.7.1.20]
131888100  adenosine deaminase-like [KO:K01488] [EC:3.5.4.4]
131880092  adenosine deaminase-like [KO:K01488] [EC:3.5.4.4]
131882191  adenosine deaminase 2-like [KO:K19572] [EC:3.5.4.4]
131882525  adenosine deaminase 2-like [KO:K19572] [EC:3.5.4.4]
131884093  adenylate kinase-like [KO:K00939] [EC:2.7.4.3]
131877347  adenylate kinase isoenzyme 1-like isoform X1 [KO:K00939] [EC:2.7.4.3]
131887603  adenylate kinase isoenzyme 1-like [KO:K00939] [EC:2.7.4.3]
131891752  adenylate kinase isoenzyme 6-like [KO:K18532] [EC:2.7.4.3]
131889597  GTP:AMP phosphotransferase AK3, mitochondrial-like [KO:K00944] [EC:2.7.4.10]
131893670  cAMP-specific 3',5'-cyclic phosphodiesterase, isoforms N/G-like isoform X1 [KO:K13293] [EC:3.1.4.53]
131876885  cAMP-specific 3',5'-cyclic phosphodiesterase-like isoform X1 [KO:K13293] [EC:3.1.4.53]
131876886  cAMP-specific 3',5'-cyclic phosphodiesterase-like isoform X1 [KO:K13293] [EC:3.1.4.53]
131887972  uncharacterized protein LOC131887972 [KO:K18436] [EC:3.1.4.53]
131879668  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A-like isoform X1 [KO:K18437] [EC:3.1.4.53]
131889093  glycerophosphocholine choline phosphodiesterase ENPP6-like isoform X1 [KO:K18424] [EC:3.6.1.29]
131891622  bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase-like isoform X1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
131889416  bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase-like [KO:K13811] [EC:2.7.7.4 2.7.1.25]
131891688  uncharacterized protein LOC131891688 [KO:K00860] [EC:2.7.1.25]
131885325  uricase-like [KO:K00365] [EC:1.7.3.3]
131878920  5-hydroxyisourate hydrolase-like [KO:K07127] [EC:3.5.2.17]
131881894  2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase-like [KO:K13485] [EC:4.1.1.97]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
tcf00030  Pentose phosphate pathway
tcf00220  Arginine biosynthesis
tcf00250  Alanine, aspartate and glutamate metabolism
tcf00260  Glycine, serine and threonine metabolism
tcf00340  Histidine metabolism
tcf00630  Glyoxylate and dicarboxylate metabolism
tcf00730  Thiamine metabolism
tcf00740  Riboflavin metabolism
tcf00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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