KEGG   PATHWAY: tdc00270
Entry
tdc00270                    Pathway                                
Name
Cysteine and methionine metabolism - Triticum dicoccoides (wild emmer wheat)
Description
Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted from serine (via acetylserine) by transfer of hydrogen sulfide [MD:M00021]. In animals, methionine-derived homocysteine is used as sulfur source and its condensation product with serine (cystathionine) is converted to cysteine [MD:M00338]. Cysteine is metabolized to pyruvate in multiple routes. Methionine is an essential amino acid, which animals cannot synthesize. In bacteria and plants, methionine is synthesized from aspartate [MD:M00017]. S-Adenosylmethionine (SAM), synthesized from methionine and ATP, is a methyl group donor in many important transfer reactions including DNA methylation for regulation of gene expression. SAM may also be used to regenerate methionine in the methionine salvage pathway [MD:M00034].
Class
Metabolism; Amino acid metabolism
Pathway map
tdc00270  Cysteine and methionine metabolism
tdc00270

Module
tdc_M00021  Cysteine biosynthesis, serine => cysteine [PATH:tdc00270]
tdc_M00034  Methionine salvage pathway [PATH:tdc00270]
tdc_M00368  Ethylene biosynthesis, methionine => ethylene [PATH:tdc00270]
Other DBs
GO: 0006534 0006555
Organism
Triticum dicoccoides (wild emmer wheat) [GN:tdc]
Gene
119291907  probable serine acetyltransferase 2 [KO:K00640] [EC:2.3.1.30]
119276969  probable serine acetyltransferase 1 [KO:K00640] [EC:2.3.1.30]
119349166  probable serine acetyltransferase 5 [KO:K00640] [EC:2.3.1.30]
119284794  probable serine acetyltransferase 4 [KO:K00640] [EC:2.3.1.30]
119268982  probable serine acetyltransferase 1 [KO:K00640] [EC:2.3.1.30]
119304015  probable serine acetyltransferase 2 [KO:K00640] [EC:2.3.1.30]
119288263  probable serine acetyltransferase 5 [KO:K00640] [EC:2.3.1.30]
119291369  probable serine acetyltransferase 4 [KO:K00640] [EC:2.3.1.30]
119325973  cysteine synthase-like isoform X1 [KO:K01738] [EC:2.5.1.47]
119329954  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
119329955  cysteine synthase, chloroplastic/chromoplastic-like isoform X1 [KO:K01738] [EC:2.5.1.47]
119330164  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
119367846  cysteine synthase-like isoform X1 [KO:K01738] [EC:2.5.1.47]
119316687  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
119298844  cysteine synthase [KO:K01738] [EC:2.5.1.47]
119267063  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
119284938  cysteine synthase 2-like [KO:K01738] [EC:2.5.1.47]
119359520  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
119287716  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
119287717  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
119307110  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
119274878  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
119311137  bifunctional L-3-cyanoalanine synthase/cysteine synthase 1, mitochondrial-like [KO:K13034] [EC:2.5.1.47 4.4.1.9]
119302459  bifunctional L-3-cyanoalanine synthase/cysteine synthase, mitochondrial-like isoform X1 [KO:K13034] [EC:2.5.1.47 4.4.1.9]
119330883  cystathionine beta-lyase, chloroplastic-like [KO:K01760] [EC:4.4.1.13]
119339932  cystathionine beta-lyase, chloroplastic-like [KO:K01760] [EC:4.4.1.13]
119281576  homocysteine S-methyltransferase 4-like [KO:K00547] [EC:2.1.1.10]
119299229  homocysteine S-methyltransferase 3-like [KO:K00547] [EC:2.1.1.10]
119284963  homocysteine S-methyltransferase 1-like [KO:K00547] [EC:2.1.1.10]
119272125  homocysteine S-methyltransferase 4-like [KO:K00547] [EC:2.1.1.10]
119307492  homocysteine S-methyltransferase 3 [KO:K00547] [EC:2.1.1.10]
119291173  homocysteine S-methyltransferase 1 [KO:K00547] [EC:2.1.1.10]
119294549  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1-like [KO:K00549] [EC:2.1.1.14]
119298863  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1-like [KO:K00549] [EC:2.1.1.14]
119287143  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1 [KO:K00549] [EC:2.1.1.14]
119307137  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1-like [KO:K00549] [EC:2.1.1.14]
119276021  S-adenosylmethionine synthase 1-like [KO:K00789] [EC:2.5.1.6]
119316513  S-adenosylmethionine synthase [KO:K00789] [EC:2.5.1.6]
119317352  S-adenosylmethionine synthase 2 [KO:K00789] [EC:2.5.1.6]
119317353  S-adenosylmethionine synthase 3 [KO:K00789] [EC:2.5.1.6]
119268092  S-adenosylmethionine synthase 1 [KO:K00789] [EC:2.5.1.6]
119320265  S-adenosylmethionine synthase 3 [KO:K00789] [EC:2.5.1.6]
119322711  S-adenosylmethionine synthase 2-like [KO:K00789] [EC:2.5.1.6]
119322785  S-adenosylmethionine synthase [KO:K00789] [EC:2.5.1.6]
119309607  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
119364786  S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
119317079  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
119355631  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
119301674  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
119322986  S-adenosylmethionine decarboxylase proenzyme-like [KO:K01611] [EC:4.1.1.50]
119327715  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
119328176  spermine synthase-like isoform X1 [KO:K00797] [EC:2.5.1.16]
119331322  spermidine synthase 1 [KO:K00797] [EC:2.5.1.16]
119301182  spermine synthase-like isoform X1 [KO:K00797] [EC:2.5.1.16]
119337561  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
119338328  spermidine synthase 1 [KO:K00797] [EC:2.5.1.16]
119342183  spermine synthase-like [KO:K00797] [EC:2.5.1.16]
119308720  spermine synthase-like [KO:K00797] [EC:2.5.1.16]
119326313  probable nicotianamine synthase 4 [KO:K05953] [EC:2.5.1.43]
119326368  nicotianamine synthase 1 [KO:K05953] [EC:2.5.1.43]
119314708  nicotianamine synthase-like 5 protein [KO:K05953] [EC:2.5.1.43]
119314969  probable nicotianamine synthase 4 [KO:K05953] [EC:2.5.1.43]
119296327  probable nicotianamine synthase 6 [KO:K05953] [EC:2.5.1.43]
119352811  nicotianamine synthase-like 5 protein isoform X1 [KO:K05953] [EC:2.5.1.43]
119352918  probable nicotianamine synthase 2 [KO:K05953] [EC:2.5.1.43]
119353188  nicotianamine synthase 9-like [KO:K05953] [EC:2.5.1.43]
119316430  nicotianamine synthase 1-like [KO:K05953] [EC:2.5.1.43]
119316432  nicotianamine synthase 1-like [KO:K05953] [EC:2.5.1.43]
119316457  nicotianamine synthase 1-like [KO:K05953] [EC:2.5.1.43]
119318492  probable nicotianamine synthase 4 [KO:K05953] [EC:2.5.1.43]
119285513  probable nicotianamine synthase 2 [KO:K05953] [EC:2.5.1.43]
119323111  nicotianamine synthase 1-like [KO:K05953] [EC:2.5.1.43]
119323112  nicotianamine synthase 1-like [KO:K05953] [EC:2.5.1.43]
119304374  probable nicotianamine synthase 2 [KO:K05953] [EC:2.5.1.43]
119361851  nicotianamine synthase-like 5 protein [KO:K05953] [EC:2.5.1.43]
119361948  probable nicotianamine synthase 2 [KO:K05953] [EC:2.5.1.43]
119362308  nicotianamine synthase 9 [KO:K05953] [EC:2.5.1.43]
119325023  nicotianamine synthase-like 5 protein [KO:K05953] [EC:2.5.1.43]
119329303  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase-like [KO:K01244] [EC:3.2.2.16]
119282035  5'-methylthioadenosine nucleosidase-like [KO:K01244] [EC:3.2.2.16]
119318699  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase-like isoform X1 [KO:K01244] [EC:3.2.2.16]
119288195  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase-like [KO:K01244] [EC:3.2.2.16]
119366266  methylthioribose kinase 1-like [KO:K00899] [EC:2.7.1.100]
119357001  methylthioribose kinase 1 [KO:K00899] [EC:2.7.1.100]
119295371  methylthioribose-1-phosphate isomerase-like [KO:K08963] [EC:5.3.1.23]
119300312  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
119307915  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
119292822  uncharacterized protein LOC119292822 [KO:K08967] [EC:1.13.11.53 1.13.11.54]
119349385  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 4-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
119316943  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 4-like isoform X1 [KO:K08967] [EC:1.13.11.53 1.13.11.54]
119283368  uncharacterized protein LOC119283368 [KO:K08967] [EC:1.13.11.53 1.13.11.54]
119358074  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 4-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
119290548  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 4-like [KO:K08967] [EC:1.13.11.53 1.13.11.54]
119309955  probable N-succinyldiaminopimelate aminotransferase DapC [KO:K23977] [EC:2.6.1.117]
119301801  probable N-succinyldiaminopimelate aminotransferase DapC [KO:K23977] [EC:2.6.1.117]
119295535  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
119316485  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
119331696  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
119318133  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
119335162  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
119285752  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
119322784  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
119323644  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
119363173  nicotianamine aminotransferase 1-like [KO:K00815] [EC:2.6.1.5]
119267336  aromatic aminotransferase ISS1-like [KO:K00837] [EC:2.6.1.-]
119275206  aromatic aminotransferase ISS1-like [KO:K00837] [EC:2.6.1.-]
119284317  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
119336475  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
119271774  methionine gamma-lyase-like [KO:K01761] [EC:4.4.1.11]
119363670  DNA (cytosine-5)-methyltransferase 1B isoform X1 [KO:K00558] [EC:2.1.1.37]
119292766  DNA (cytosine-5)-methyltransferase CMT1-like [KO:K00558] [EC:2.1.1.37]
119329745  DNA (cytosine-5)-methyltransferase 1-like [KO:K00558] [EC:2.1.1.37]
119283412  DNA (cytosine-5)-methyltransferase CMT1-like [KO:K00558] [EC:2.1.1.37]
119284473  DNA (cytosine-5)-methyltransferase CMT3-like [KO:K00558] [EC:2.1.1.37]
119300233  LOW QUALITY PROTEIN: DNA (cytosine-5)-methyltransferase 1A-like [KO:K00558] [EC:2.1.1.37]
119318456  DNA (cytosine-5)-methyltransferase 1-like isoform X1 [KO:K00558] [EC:2.1.1.37]
119334104  DNA (cytosine-5)-methyltransferase CMT1-like [KO:K00558] [EC:2.1.1.37]
119334730  DNA (cytosine-5)-methyltransferase 1A-like isoform X1 [KO:K00558] [EC:2.1.1.37]
119319258  DNA (cytosine-5)-methyltransferase CMT3-like [KO:K00558] [EC:2.1.1.37]
119285321  DNA (cytosine-5)-methyltransferase CMT2-like isoform X1 [KO:K00558] [EC:2.1.1.37]
119357858  DNA (cytosine-5)-methyltransferase 1B-like [KO:K00558] [EC:2.1.1.37]
119323478  DNA (cytosine-5)-methyltransferase CMT3-like isoform X1 [KO:K00558] [EC:2.1.1.37]
119339671  DNA (cytosine-5)-methyltransferase 1-like [KO:K00558] [EC:2.1.1.37]
119306462  DNA (cytosine-5)-methyltransferase 1A-like [KO:K00558] [EC:2.1.1.37]
119324139  DNA (cytosine-5)-methyltransferase 1-like isoform X1 [KO:K00558] [EC:2.1.1.37]
119340985  DNA (cytosine-5)-methyltransferase 1A-like [KO:K00558] [EC:2.1.1.37]
119290777  DNA (cytosine-5)-methyltransferase CMT2-like [KO:K00558] [EC:2.1.1.37]
119325869  proline-rich protein 12-like isoform X1 [KO:K17398] [EC:2.1.1.37]
119364823  bromodomain-containing protein 4-like isoform X1 [KO:K17398] [EC:2.1.1.37]
119365895  adenosylhomocysteinase-like [KO:K01251] [EC:3.13.2.1]
119365934  adenosylhomocysteinase [KO:K01251] [EC:3.13.2.1]
119356680  adenosylhomocysteinase-like [KO:K01251] [EC:3.13.2.1]
119356709  adenosylhomocysteinase-like [KO:K01251] [EC:3.13.2.1]
119365129  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
119355993  1-aminocyclopropane-1-carboxylate synthase-like [KO:K20772] [EC:4.4.1.14]
119294913  1-aminocyclopropane-1-carboxylate synthase 1-like [KO:K01762] [EC:4.4.1.14]
119267206  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
119286804  1-aminocyclopropane-1-carboxylate synthase 1-like [KO:K01762] [EC:4.4.1.14]
119275063  1-aminocyclopropane-1-carboxylate synthase 7-like [KO:K01762] [EC:4.4.1.14]
119309902  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
119309907  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
119325893  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
119325903  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
119326530  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
119364849  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
119364859  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
119295291  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
119318031  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
119318032  1-aminocyclopropane-1-carboxylate oxidase 3-like [KO:K05933] [EC:1.14.17.4]
119318033  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
119318035  1-aminocyclopropane-1-carboxylate oxidase 3-like [KO:K05933] [EC:1.14.17.4]
119334362  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
119335741  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
119301783  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
119301784  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
119320090  1-aminocyclopropane-1-carboxylate oxidase 1-like isoform X1 [KO:K05933] [EC:1.14.17.4]
119320303  1-aminocyclopropane-1-carboxylate oxidase 3-like isoform X1 [KO:K05933] [EC:1.14.17.4]
119286479  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
119323684  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
119340494  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
119325003  1-aminocyclopropane-1-carboxylate oxidase 1-like [KO:K05933] [EC:1.14.17.4]
119310670  aspartokinase 1, chloroplastic-like [KO:K00928] [EC:2.7.2.4]
119312833  aspartokinase 1, chloroplastic-like [KO:K00928] [EC:2.7.2.4]
119278259  aspartokinase 2, chloroplastic-like [KO:K00928] [EC:2.7.2.4]
119270192  aspartokinase 2, chloroplastic-like [KO:K00928] [EC:2.7.2.4]
119287419  aspartokinase 1, chloroplastic-like [KO:K00928] [EC:2.7.2.4]
119339597  aspartokinase 1, chloroplastic-like [KO:K00928] [EC:2.7.2.4]
119301233  bifunctional aspartokinase/homoserine dehydrogenase 2, chloroplastic isoform X1 [KO:K12524] [EC:2.7.2.4 1.1.1.3]
119308766  bifunctional aspartokinase/homoserine dehydrogenase 2, chloroplastic-like isoform X1 [KO:K12524] [EC:2.7.2.4 1.1.1.3]
119311901  aspartate-semialdehyde dehydrogenase-like [KO:K00133] [EC:1.2.1.11]
119303233  aspartate-semialdehyde dehydrogenase-like [KO:K00133] [EC:1.2.1.11]
119300898  bifunctional aspartokinase/homoserine dehydrogenase 1-like [KO:K00003] [EC:1.1.1.3]
119308410  bifunctional aspartokinase/homoserine dehydrogenase 1-like [KO:K00003] [EC:1.1.1.3]
119343815  cystathionine gamma-synthase 1, chloroplastic-like [KO:K01739] [EC:2.5.1.48]
119344617  cystathionine gamma-synthase 1, chloroplastic-like [KO:K01739] [EC:2.5.1.48]
119344680  cystathionine gamma-synthase 1, chloroplastic-like [KO:K01739] [EC:2.5.1.48]
119345168  cystathionine gamma-synthase 1, chloroplastic-like [KO:K01739] [EC:2.5.1.48]
119346144  probable cystathionine gamma-synthase 2 [KO:K01739] [EC:2.5.1.48]
119347801  cystathionine gamma-synthase 1, chloroplastic-like [KO:K01739] [EC:2.5.1.48]
119367033  probable cystathionine gamma-synthase 2 [KO:K01739] [EC:2.5.1.48]
119367034  probable cystathionine gamma-synthase 2 [KO:K01739] [EC:2.5.1.48]
119367037  probable cystathionine gamma-synthase 2 [KO:K01739] [EC:2.5.1.48]
119367040  probable cystathionine gamma-synthase 2 [KO:K01739] [EC:2.5.1.48]
119296170  cystathionine gamma-synthase 1, chloroplastic-like isoform X1 [KO:K01739] [EC:2.5.1.48]
119285889  cystathionine gamma-synthase 1, chloroplastic-like isoform X1 [KO:K01739] [EC:2.5.1.48]
119357507  probable cystathionine gamma-synthase 2 [KO:K01739] [EC:2.5.1.48]
119292152  branched-chain amino acid aminotransferase 2, chloroplastic-like isoform X1 [KO:K00826] [EC:2.6.1.42]
119365238  branched-chain amino acid aminotransferase 2, chloroplastic-like isoform X1 [KO:K00826] [EC:2.6.1.42]
119285012  branched-chain-amino-acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
119356096  branched-chain amino acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
119338670  branched-chain amino acid aminotransferase 2, chloroplastic-like [KO:K00826] [EC:2.6.1.42]
119304243  branched-chain amino acid aminotransferase 2, chloroplastic-like isoform X1 [KO:K00826] [EC:2.6.1.42]
119274910  branched-chain amino acid aminotransferase 2, chloroplastic-like isoform X1 [KO:K00826] [EC:2.6.1.42]
119291115  branched-chain-amino-acid aminotransferase 2, chloroplastic-like isoform X1 [KO:K00826] [EC:2.6.1.42]
119291579  alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
119348682  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
119296203  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial-like isoform X1 [KO:K00827] [EC:2.6.1.44 2.6.1.40]
119283776  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
119284591  alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial-like [KO:K00827] [EC:2.6.1.44 2.6.1.40]
119322959  glutamate--cysteine ligase B, chloroplastic-like [KO:K01919] [EC:6.3.2.2]
119363431  glutamate--cysteine ligase B, chloroplastic [KO:K01919] [EC:6.3.2.2]
119329657  glutathione synthetase, chloroplastic-like isoform X1 [KO:K21456] [EC:6.3.2.3]
119315840  glutathione synthetase, chloroplastic-like [KO:K21456] [EC:6.3.2.3]
119300288  glutathione synthetase, chloroplastic-like [KO:K21456] [EC:6.3.2.3]
119337085  glutathione synthetase, chloroplastic-like [KO:K21456] [EC:6.3.2.3]
119324306  glutathione synthetase, chloroplastic-like [KO:K21456] [EC:6.3.2.3]
119307919  glutathione synthetase, chloroplastic-like [KO:K21456] [EC:6.3.2.3]
119277054  aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
119269062  aspartate aminotransferase, cytoplasmic-like [KO:K14454] [EC:2.6.1.1]
119330792  aspartate aminotransferase, mitochondrial-like [KO:K14455] [EC:2.6.1.1]
119319280  aspartate aminotransferase, mitochondrial-like [KO:K14455] [EC:2.6.1.1]
119322700  aspartate aminotransferase, mitochondrial-like [KO:K14455] [EC:2.6.1.1]
119338875  aspartate aminotransferase, mitochondrial-like [KO:K14455] [EC:2.6.1.1]
119318325  aspartate aminotransferase, chloroplastic-like isoform X1 [KO:K00811] [EC:2.6.1.1]
119323469  aspartate aminotransferase, chloroplastic-like isoform X1 [KO:K00811] [EC:2.6.1.1]
119364683  thiosulfate sulfurtransferase-like isoform X1 [KO:K01011] [EC:2.8.1.1 2.8.1.2]
119315818  thiosulfate/3-mercaptopyruvate sulfurtransferase 1, mitochondrial-like [KO:K01011] [EC:2.8.1.1 2.8.1.2]
119315821  thiosulfate/3-mercaptopyruvate sulfurtransferase 1, mitochondrial-like [KO:K01011] [EC:2.8.1.1 2.8.1.2]
119299212  thiosulfate/3-mercaptopyruvate sulfurtransferase 2-like [KO:K01011] [EC:2.8.1.1 2.8.1.2]
119355528  uncharacterized protein LOC119355528 isoform X1 [KO:K01011] [EC:2.8.1.1 2.8.1.2]
119323143  thiosulfate/3-mercaptopyruvate sulfurtransferase 1, mitochondrial-like [KO:K01011] [EC:2.8.1.1 2.8.1.2]
119323144  thiosulfate/3-mercaptopyruvate sulfurtransferase 1, mitochondrial-like [KO:K01011] [EC:2.8.1.1 2.8.1.2]
119307503  thiosulfate/3-mercaptopyruvate sulfurtransferase 2-like isoform X1 [KO:K01011] [EC:2.8.1.1 2.8.1.2]
119328302  L-lactate dehydrogenase B-like [KO:K00016] [EC:1.1.1.27]
119349461  L-lactate dehydrogenase B-like [KO:K00016] [EC:1.1.1.27]
119314858  L-lactate dehydrogenase A-like [KO:K00016] [EC:1.1.1.27]
119367127  L-lactate dehydrogenase B-like [KO:K00016] [EC:1.1.1.27]
119358832  L-lactate dehydrogenase B [KO:K00016] [EC:1.1.1.27]
119323214  L-lactate dehydrogenase A [KO:K00016] [EC:1.1.1.27]
119340369  L-lactate dehydrogenase B-like [KO:K00016] [EC:1.1.1.27]
119340542  L-lactate dehydrogenase B-like [KO:K00016] [EC:1.1.1.27]
119276671  putative D-cysteine desulfhydrase 2, mitochondrial [KO:K05396] [EC:4.4.1.15]
119279395  putative D-cysteine desulfhydrase 1, mitochondrial [KO:K05396] [EC:4.4.1.15]
119268736  putative D-cysteine desulfhydrase 2, mitochondrial [KO:K05396] [EC:4.4.1.15]
119303674  putative D-cysteine desulfhydrase 1, mitochondrial [KO:K05396] [EC:4.4.1.15]
119323244  putative D-cysteine desulfhydrase 1, mitochondrial [KO:K05396] [EC:4.4.1.15]
119306513  putative D-cysteine desulfhydrase 1, mitochondrial [KO:K05396] [EC:4.4.1.15]
119276115  putative L-cysteine desulfhydrase 1 isoform X1 [KO:K22207] [EC:4.4.1.28]
119268049  putative L-cysteine desulfhydrase 1 [KO:K22207] [EC:4.4.1.28]
119332873  malate dehydrogenase, cytoplasmic [KO:K00025] [EC:1.1.1.37]
119269103  malate dehydrogenase, cytoplasmic-like [KO:K00025] [EC:1.1.1.37]
119276401  malate dehydrogenase 1, mitochondrial-like [KO:K00026] [EC:1.1.1.37]
119293066  malate dehydrogenase 1, mitochondrial-like [KO:K00026] [EC:1.1.1.37]
119311978  malate dehydrogenase, glyoxysomal-like [KO:K00026] [EC:1.1.1.37]
119328995  malate dehydrogenase, chloroplastic-like [KO:K00026] [EC:1.1.1.37]
119349120  malate dehydrogenase, chloroplastic-like [KO:K00026] [EC:1.1.1.37]
119349661  malate dehydrogenase, mitochondrial-like [KO:K00026] [EC:1.1.1.37]
119298802  malate dehydrogenase, glyoxysomal [KO:K00026] [EC:1.1.1.37]
119268512  malate dehydrogenase 1, mitochondrial-like [KO:K00026] [EC:1.1.1.37]
119336902  malate dehydrogenase, chloroplastic-like [KO:K00026] [EC:1.1.1.37]
119303315  malate dehydrogenase, glyoxysomal-like [KO:K00026] [EC:1.1.1.37]
119287810  malate dehydrogenase, chloroplastic-like [KO:K00026] [EC:1.1.1.37]
119307052  malate dehydrogenase, glyoxysomal-like [KO:K00026] [EC:1.1.1.37]
119277364  cysteine synthase-like [KO:K22846] [EC:2.5.1.144]
119269365  cysteine synthase-like [KO:K22846] [EC:2.5.1.144]
119275971  D-3-phosphoglycerate dehydrogenase 3, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
119366048  D-3-phosphoglycerate dehydrogenase 1, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
119330637  D-3-phosphoglycerate dehydrogenase 3, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
119267601  D-3-phosphoglycerate dehydrogenase 3, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
119356812  D-3-phosphoglycerate dehydrogenase 1, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
119339367  D-3-phosphoglycerate dehydrogenase 3, chloroplastic-like [KO:K00058] [EC:1.1.1.95 1.1.1.399]
119291461  phosphoserine aminotransferase 1, chloroplastic-like [KO:K00831] [EC:2.6.1.52]
119284710  phosphoserine aminotransferase 1, chloroplastic-like [KO:K00831] [EC:2.6.1.52]
Compound
C00019  S-Adenosyl-L-methionine
C00021  S-Adenosyl-L-homocysteine
C00022  Pyruvate
C00041  L-Alanine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00065  L-Serine
C00073  L-Methionine
C00094  Sulfite
C00097  L-Cysteine
C00109  2-Oxobutanoate
C00155  L-Homocysteine
C00170  5'-Methylthioadenosine
C00197  3-Phospho-D-glycerate
C00263  L-Homoserine
C00283  Hydrogen sulfide
C00409  Methanethiol
C00441  L-Aspartate 4-semialdehyde
C00491  L-Cystine
C00506  L-Cysteate
C00606  3-Sulfino-L-alanine
C00793  D-Cysteine
C00957  Mercaptopyruvate
C00979  O-Acetyl-L-serine
C01005  O-Phospho-L-serine
C01077  O-Acetyl-L-homoserine
C01118  O-Succinyl-L-homoserine
C01137  S-Adenosylmethioninamine
C01180  4-Methylthio-2-oxobutanoic acid
C01234  1-Aminocyclopropane-1-carboxylate
C01817  L-Homocystine
C01962  Thiocysteine
C02218  Dehydroalanine
C02291  L-Cystathionine
C02356  (S)-2-Aminobutanoate
C02989  L-Methionine S-oxide
C03082  4-Phospho-L-aspartate
C03089  5-Methylthio-D-ribose
C03145  N-Formylmethionine
C03232  3-Phosphonooxypyruvate
C03431  S-Inosyl-L-homocysteine
C03539  S-Ribosyl-L-homocysteine
C04188  S-Methyl-5-thio-D-ribose 1-phosphate
C04582  S-Methyl-5-thio-D-ribulose 1-phosphate
C05324  Nicotianamine
C05524  Aminoacyl-L-methionine
C05526  S-Glutathionyl-L-cysteine
C05527  3-Sulfinylpyruvate
C05528  3-Sulfopyruvate
C05823  3-Mercaptolactate
C05824  S-Sulfo-L-cysteine
C06547  Ethylene
C08276  3-(Methylthio)propanoate
C09306  Sulfur dioxide
C11437  1-Deoxy-D-xylulose 5-phosphate
C11481  HSO3-
C11499  (S)-3-Sulfolactate
C11537  (2R)-3-Sulfolactate
C15606  1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one
C15650  2,3-Diketo-5-methylthiopentyl-1-phosphate
C15651  2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate
C18049  N-Acyl-L-homoserine lactone
C19787  5'-S-Methyl-5'-thioinosine
C21015  gamma-L-Glutamyl-L-2-aminobutyrate
C21016  Ophthalmate
C22359  S-Methyl-1-thio-D-xylulose 5-phosphate
Reference
PMID:15102328
  Authors
Sekowska A, Denervaud V, Ashida H, Michoud K, Haas D, Yokota A, Danchin A
  Title
Bacterial variations on the methionine salvage pathway.
  Journal
BMC Microbiol 4:9 (2004)
DOI:10.1186/1471-2180-4-9
Reference
PMID:14551435
  Authors
Ashida H, Saito Y, Kojima C, Kobayashi K, Ogasawara N, Yokota A.
  Title
A functional link between RuBisCO-like protein of Bacillus and photosynthetic RuBisCO.
  Journal
Science 302:286-90 (2003)
DOI:10.1126/science.1086997
Reference
PMID:12022921
  Authors
Sekowska A, Danchin A.
  Title
The methionine salvage pathway in Bacillus subtilis.
  Journal
BMC Microbiol 2:8 (2002)
DOI:10.1186/1471-2180-2-8
Reference
PMID:12670965
  Authors
Berger BJ, English S, Chan G, Knodel MH.
  Title
Methionine regeneration and aminotransferases in Bacillus subtilis, Bacillus cereus, and Bacillus anthracis.
  Journal
J Bacteriol 185:2418-31 (2003)
DOI:10.1128/JB.185.8.2418-2431.2003
Reference
PMID:17169919
  Authors
Goyer A, Collakova E, Shachar-Hill Y, Hanson AD
  Title
Functional characterization of a methionine gamma-lyase in Arabidopsis and its implication in an alternative to the reverse trans-sulfuration pathway.
  Journal
Plant Cell Physiol 48:232-42 (2007)
DOI:10.1093/pcp/pcl055
Reference
PMID:17030798
  Authors
Rebeille F, Jabrin S, Bligny R, Loizeau K, Gambonnet B, Van Wilder V, Douce R, Ravanel S
  Title
Methionine catabolism in Arabidopsis cells is initiated by a gamma-cleavage process and leads to S-methylcysteine and isoleucine syntheses.
  Journal
Proc Natl Acad Sci U S A 103:15687-92 (2006)
DOI:10.1073/pnas.0606195103
Reference
PMID:18625006
  Authors
Pirkov I, Norbeck J, Gustafsson L, Albers E
  Title
A complete inventory of all enzymes in the eukaryotic methionine salvage pathway.
  Journal
FEBS J 275:4111-20 (2008)
DOI:10.1111/j.1742-4658.2008.06552.x
Reference
PMID:18391471
  Authors
Ashida H, Saito Y, Kojima C, Yokota A
  Title
Enzymatic characterization of 5-methylthioribulose-1-phosphate dehydratase of the methionine salvage pathway in Bacillus subtilis.
  Journal
Biosci Biotechnol Biochem 72:959-67 (2008)
DOI:10.1271/bbb.70651
Reference
PMID:10613873
  Authors
Kitabatake M, So MW, Tumbula DL, Soll D
  Title
Cysteine biosynthesis pathway in the archaeon Methanosarcina barkeri encoded by acquired bacterial genes?
  Journal
J Bacteriol 182:143-5 (2000)
DOI:10.1128/JB.182.1.143-145.2000
Reference
PMID:12644499
  Authors
Mino K, Ishikawa K
  Title
Characterization of a novel thermostable O-acetylserine sulfhydrylase from Aeropyrum pernix K1.
  Journal
J Bacteriol 185:2277-84 (2003)
DOI:10.1128/JB.185.7.2277-2284.2003
Reference
PMID:18520135
  Authors
Tanabe S
  Title
Development of assay methods for endogenous inorganic sulfur compounds and sulfurtransferases and evaluation of the physiological functions of bound sulfur.
  Journal
Yakugaku Zasshi 128:881-900 (2008)
DOI:10.1248/yakushi.128.881
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
PMID:19270684
  Authors
Gutierrez JA, Crowder T, Rinaldo-Matthis A, Ho MC, Almo SC, Schramm VL
  Title
Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing.
  Journal
Nat Chem Biol 5:251-7 (2009)
DOI:10.1038/nchembio.153
Related
pathway
tdc00010  Glycolysis / Gluconeogenesis
tdc00250  Alanine, aspartate and glutamate metabolism
tdc00260  Glycine, serine and threonine metabolism
tdc00290  Valine, leucine and isoleucine biosynthesis
tdc00430  Taurine and hypotaurine metabolism
tdc00480  Glutathione metabolism
tdc00620  Pyruvate metabolism
tdc00640  Propanoate metabolism
tdc00770  Pantothenate and CoA biosynthesis
tdc00900  Terpenoid backbone biosynthesis
tdc00920  Sulfur metabolism
KO pathway
ko00270   
LinkDB

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