KEGG   PATHWAY: twl00230
Entry
twl00230                    Pathway                                
Name
Purine metabolism - Tripterygium wilfordii (thunder duke vine)
Class
Metabolism; Nucleotide metabolism
Pathway map
twl00230  Purine metabolism
twl00230

Module
twl_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:twl00230]
twl_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:twl00230]
twl_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:twl00230]
twl_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:twl00230]
twl_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:twl00230]
Other DBs
GO: 0006163 0042278
Organism
Tripterygium wilfordii (thunder duke vine) [GN:twl]
Gene
119985279  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
119989900  nudix hydrolase 10-like [KO:K26956] [EC:3.6.1.13 3.6.1.22]
120000276  nudix hydrolase 2-like [KO:K26956] [EC:3.6.1.13 3.6.1.22]
119988411  nudix hydrolase 2-like isoform X1 [KO:K26956] [EC:3.6.1.13 3.6.1.22]
120007800  nudix hydrolase 2-like [KO:K26956] [EC:3.6.1.13 3.6.1.22]
120012786  nudix hydrolase 23, chloroplastic-like isoform X1 [KO:K18453] [EC:3.6.1.13 3.6.1.18]
119995661  nudix hydrolase 23, chloroplastic-like [KO:K18453] [EC:3.6.1.13 3.6.1.18]
119980619  nudix hydrolase 14, chloroplastic [KO:K18447] [EC:3.6.1.21]
120013588  phosphoglucomutase, cytoplasmic [KO:K01835] [EC:5.4.2.2]
119985679  phosphoglucomutase, chloroplastic isoform X1 [KO:K01835] [EC:5.4.2.2]
119998447  phosphoglucomutase, cytoplasmic-like [KO:K01835] [EC:5.4.2.2]
120017065  ribose-phosphate pyrophosphokinase 1 isoform X1 [KO:K00948] [EC:2.7.6.1]
119983651  ribose-phosphate pyrophosphokinase 1-like [KO:K00948] [EC:2.7.6.1]
119986633  ribose-phosphate pyrophosphokinase 1-like [KO:K00948] [EC:2.7.6.1]
120001338  amidophosphoribosyltransferase, chloroplastic-like [KO:K00764] [EC:2.4.2.14]
120002130  amidophosphoribosyltransferase, chloroplastic-like [KO:K00764] [EC:2.4.2.14]
119991696  amidophosphoribosyltransferase, chloroplastic-like [KO:K00764] [EC:2.4.2.14]
119981409  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
120016027  phosphoribosylglycinamide formyltransferase, chloroplastic isoform X1 [KO:K00601] [EC:2.1.2.2]
120006979  probable phosphoribosylformylglycinamidine synthase, chloroplastic/mitochondrial [KO:K01952] [EC:6.3.5.3]
120013286  phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic/mitochondrial-like [KO:K01933] [EC:6.3.3.1]
120013318  phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic/mitochondrial-like [KO:K01933] [EC:6.3.3.1]
120014483  phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic/mitochondrial-like [KO:K01933] [EC:6.3.3.1]
119987566  phosphoribosylaminoimidazole carboxylase, chloroplastic-like isoform X1 [KO:K11808] [EC:4.1.1.21]
120009191  phosphoribosylaminoimidazole-succinocarboxamide synthase, chloroplastic [KO:K01923] [EC:6.3.2.6]
120013086  adenylosuccinate lyase-like [KO:K01756] [EC:4.3.2.2]
119995815  bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
120016288  adenine phosphoribosyltransferase 4-like [KO:K00759] [EC:2.4.2.7]
119993047  adenine phosphoribosyltransferase 5-like isoform X1 [KO:K00759] [EC:2.4.2.7]
119997655  adenine phosphoribosyltransferase 5-like isoform X1 [KO:K00759] [EC:2.4.2.7]
120009570  adenine phosphoribosyltransferase 1-like [KO:K00759] [EC:2.4.2.7]
119986405  adenine phosphoribosyltransferase 3-like [KO:K00759] [EC:2.4.2.7]
120010125  adenine phosphoribosyltransferase 1, chloroplastic-like [KO:K00759] [EC:2.4.2.7]
120010649  adenine phosphoribosyltransferase 1, chloroplastic-like [KO:K00759] [EC:2.4.2.7]
120001563  5'-nucleotidase SurE-like [KO:K03787] [EC:3.1.3.5 3.1.3.6]
120014603  5'-nucleotidase SurE-like [KO:K03787] [EC:3.1.3.5 3.1.3.6]
120004592  5'-nucleotidase SurE-like [KO:K03787] [EC:3.1.3.5 3.1.3.6]
119998910  5'-nucleotidase SurE-like [KO:K03787] [EC:3.1.3.5 3.1.3.6]
120016297  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
119988243  inosine-5'-monophosphate dehydrogenase 2 [KO:K00088] [EC:1.1.1.205]
119983204  inosine-5'-monophosphate dehydrogenase 2-like [KO:K00088] [EC:1.1.1.205]
119987215  nucleoside diphosphate kinase 3-like [KO:K00940] [EC:2.7.4.6]
119981066  nucleoside diphosphate kinase 3-like isoform X1 [KO:K00940] [EC:2.7.4.6]
119981721  nucleoside diphosphate kinase B-like [KO:K00940] [EC:2.7.4.6]
119984076  nucleoside diphosphate kinase B [KO:K00940] [EC:2.7.4.6]
119986115  nucleoside diphosphate kinase 2, chloroplastic [KO:K00940] [EC:2.7.4.6]
120001959  probable apyrase 6 [KO:K01510] [EC:3.6.1.5]
120002713  probable apyrase 6 [KO:K01510] [EC:3.6.1.5]
120008883  probable apyrase 6 [KO:K01510] [EC:3.6.1.5]
119993852  apyrase 2-like [KO:K14641] [EC:3.6.1.5]
119997726  apyrase 2-like [KO:K14641] [EC:3.6.1.5]
120015186  inosine triphosphate pyrophosphatase-like isoform X1 [KO:K01519] [EC:3.6.1.66]
120007020  inosine triphosphate pyrophosphatase isoform X1 [KO:K01519] [EC:3.6.1.66]
119996112  xanthine dehydrogenase 1-like isoform X1 [KO:K00106] [EC:1.17.1.4 1.17.3.2]
119990830  nudix hydrolase 25-like [KO:K26955] [EC:3.6.1.17]
120001617  nudix hydrolase 25-like [KO:K26955] [EC:3.6.1.17]
119987549  GMP synthase [glutamine-hydrolyzing]-like [KO:K01951] [EC:6.3.5.2]
120017149  GMP synthase [glutamine-hydrolyzing]-like [KO:K01951] [EC:6.3.5.2]
120012777  guanylate kinase 3, chloroplastic-like [KO:K00942] [EC:2.7.4.8]
120013309  guanylate kinase 2 [KO:K00942] [EC:2.7.4.8]
119985258  guanylate kinase 2-like isoform X1 [KO:K00942] [EC:2.7.4.8]
119992100  ribonucleoside-diphosphate reductase large subunit [KO:K10807] [EC:1.17.4.1]
120008415  ribonucleoside-diphosphate reductase large subunit-like isoform X1 [KO:K10807] [EC:1.17.4.1]
120013504  ribonucleoside-diphosphate reductase small chain A [KO:K10808] [EC:1.17.4.1]
119996208  ribonucleoside-diphosphate reductase small chain [KO:K10808] [EC:1.17.4.1]
119996356  ribonucleoside-diphosphate reductase small chain-like [KO:K10808] [EC:1.17.4.1]
120001425  5'-deoxynucleotidase HDDC2 [KO:K07023] [EC:3.1.3.89]
120004995  5'-deoxynucleotidase HDDC2 isoform X1 [KO:K07023] [EC:3.1.3.89]
119980427  protein prune homolog 2-like [KO:K01514] [EC:3.6.1.11]
120013539  probable GTP diphosphokinase RSH2, chloroplastic isoform X1 [KO:K00951] [EC:2.7.6.5]
120002274  probable GTP diphosphokinase RSH2, chloroplastic [KO:K00951] [EC:2.7.6.5]
119981616  putative GTP diphosphokinase RSH1, chloroplastic isoform X1 [KO:K00951] [EC:2.7.6.5]
120005984  probable GTP diphosphokinase CRSH, chloroplastic [KO:K00951] [EC:2.7.6.5]
119984860  putative GTP diphosphokinase RSH1, chloroplastic [KO:K00951] [EC:2.7.6.5]
119991849  phytosulfokine receptor 1 [KO:K27625] [EC:2.7.11.1 4.6.1.2]
119995424  adenylosuccinate synthetase 2, chloroplastic [KO:K01939] [EC:6.3.4.4]
119999071  adenylosuccinate synthetase 2, chloroplastic-like [KO:K01939] [EC:6.3.4.4]
120013721  AMP deaminase-like isoform X1 [KO:K01490] [EC:3.5.4.6]
119993379  AMP deaminase [KO:K01490] [EC:3.5.4.6]
119990234  adenosine kinase 2-like [KO:K00856] [EC:2.7.1.20]
120004751  adenosine kinase 1-like [KO:K00856] [EC:2.7.1.20]
119999015  adenosine kinase 1 [KO:K00856] [EC:2.7.1.20]
120011226  probable adenylate kinase 7, mitochondrial [KO:K00939] [EC:2.7.4.3]
120000125  adenylate kinase 4-like isoform X1 [KO:K00939] [EC:2.7.4.3]
120000128  adenylate kinase 4-like isoform X1 [KO:K00939] [EC:2.7.4.3]
119988867  probable adenylate kinase 6, chloroplastic [KO:K00939] [EC:2.7.4.3]
119980241  probable adenylate kinase 6, chloroplastic [KO:K00939] [EC:2.7.4.3]
120004892  probable adenylate kinase 6, chloroplastic [KO:K00939] [EC:2.7.4.3]
119983561  adenylate kinase 4 [KO:K00939] [EC:2.7.4.3]
119996457  adenylate kinase 5, chloroplastic [KO:K00939] [EC:2.7.4.3]
119984704  adenylate kinase, chloroplastic [KO:K00939] [EC:2.7.4.3]
119985094  probable adenylate kinase 7, mitochondrial isoform X1 [KO:K00939] [EC:2.7.4.3]
119985952  adenylate kinase 4-like [KO:K00939] [EC:2.7.4.3]
120016252  adenylate kinase isoenzyme 6 homolog [KO:K18532] [EC:2.7.4.3]
120016987  cancer-related nucleoside-triphosphatase homolog isoform X1 [KO:K06928] [EC:3.6.1.15]
119993088  ectonucleotide pyrophosphatase/phosphodiesterase family member 3-like [KO:K01513] [EC:3.1.4.1 3.6.1.9]
119996780  venom phosphodiesterase-like [KO:K01513] [EC:3.1.4.1 3.6.1.9]
119992866  bifunctional bis(5'-adenosyl)-triphosphatase/adenylylsulfatase FHIT isoform X1 [KO:K01522] [EC:3.6.1.29]
120000803  ATP sulfurylase 2-like isoform X1 [KO:K13811] [EC:2.7.7.4 2.7.1.25]
120014575  ATP sulfurylase 1, chloroplastic-like [KO:K13811] [EC:2.7.7.4 2.7.1.25]
120003519  ATP sulfurylase 1, chloroplastic-like [KO:K13811] [EC:2.7.7.4 2.7.1.25]
120009860  ATP sulfurylase 2-like [KO:K13811] [EC:2.7.7.4 2.7.1.25]
120014864  adenylyl-sulfate kinase 3-like [KO:K00860] [EC:2.7.1.25]
119982195  adenylyl-sulfate kinase, chloroplastic-like isoform X1 [KO:K00860] [EC:2.7.1.25]
119984732  adenylyl-sulfate kinase 3-like [KO:K00860] [EC:2.7.1.25]
119997825  adenylyl-sulfate kinase 3-like [KO:K00860] [EC:2.7.1.25]
119989287  uricase-2 [KO:K00365] [EC:1.7.3.3]
119982907  uric acid degradation bifunctional protein TTL isoform X1 [KO:K13484] [EC:3.5.2.17 4.1.1.97]
119989902  allantoinase isoform X1 [KO:K01466] [EC:3.5.2.5]
119988211  allantoate deiminase 2-like [KO:K02083] [EC:3.5.3.9]
120004898  allantoate deiminase 2 [KO:K02083] [EC:3.5.3.9]
120016816  (S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
120015476  ureidoglycolate hydrolase [KO:K18151] [EC:3.5.1.116]
120000124  urease [KO:K01427] [EC:3.5.1.5]
120000127  urease-like [KO:K01427] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
twl00030  Pentose phosphate pathway
twl00220  Arginine biosynthesis
twl00250  Alanine, aspartate and glutamate metabolism
twl00260  Glycine, serine and threonine metabolism
twl00340  Histidine metabolism
twl00630  Glyoxylate and dicarboxylate metabolism
twl00730  Thiamine metabolism
twl00740  Riboflavin metabolism
twl00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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