KEGG   PATHWAY: plg00230
Entry
plg00230                    Pathway                                
Name
Purine metabolism - Paucimonas lemoignei
Class
Metabolism; Nucleotide metabolism
Pathway map
plg00230  Purine metabolism
plg00230

Module
plg_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:plg00230]
plg_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:plg00230]
plg_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:plg00230]
plg_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:plg00230]
plg_M00546  Purine degradation, xanthine => urea [PATH:plg00230]
plg_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:plg00230]
plg_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:plg00230]
Other DBs
GO: 0006163 0042278
Organism
Paucimonas lemoignei [GN:plg]
Gene
NCTC10937_00726  nudF; mutT/nudix family protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
NCTC10937_00248  nudE; ADP-ribose diphosphatase NudE [KO:K08312] [EC:3.6.1.-]
NCTC10937_02652  pgm; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
NCTC10937_00185  algC; phosphomannomutase/phosphoglucomutase AlgC [KO:K15778] [EC:5.4.2.8 5.4.2.2]
NCTC10937_01730  purF_1; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
NCTC10937_00839  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
NCTC10937_04038  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
NCTC10937_01396  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
NCTC10937_01389  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
NCTC10937_04037  purM; protein PurM [KO:K01933] [EC:6.3.3.1]
NCTC10937_05198  purK; phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
NCTC10937_05199  purE; phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
NCTC10937_01560  purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
NCTC10937_03528  purB; adenylosuccinate lyase PurB [KO:K01756] [EC:4.3.2.2]
NCTC10937_00840  purH; bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
NCTC10937_03730  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
NCTC10937_02258  5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
NCTC10937_01495  surE; stationary phase survival protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
NCTC10937_00247  HAD superfamily hydrolase [KO:K20881] [EC:3.1.3.-]
NCTC10937_03637  Uncharacterized protein conserved in bacteria [KO:K09913] [EC:2.4.2.1 2.4.2.2]
NCTC10937_00959  yfiH; multi-copper polyphenol oxidoreductase, laccase [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
NCTC10937_04374  hpt; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
NCTC10937_01376  guaB; inosine-5-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
NCTC10937_01359  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
NCTC10937_00362  rdgB; non-canonical purine NTP pyrophosphatase RdgB [KO:K01519] [EC:3.6.1.66]
NCTC10937_00181  xpt; xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
NCTC10937_03752  hcrC; xanthine dehydrogenase, small subunit [KO:K13481] [EC:1.17.1.4]
NCTC10937_03753  hcrA_4; xanthine dehydrogenase [KO:K13482] [EC:1.17.1.4]
NCTC10937_00908  hcrA_1; aldehyde oxidase and xanthine dehydrogenase [KO:K11177] [EC:1.17.1.4]
NCTC10937_03037  hcrA_3; aldehyde oxidase and xanthine dehydrogenase family protein [KO:K11177] [EC:1.17.1.4]
NCTC10937_02408  hcrA_2; xanthine dehydrogenase, molybdenum binding subunit apoprotein [KO:K11177] [EC:1.17.1.4]
NCTC10937_03036  hcrB_3; oxidoreductase, molybdopterin-binding subunit [KO:K11178] [EC:1.17.1.4]
NCTC10937_02409  hcrB_2; molybdopterin dehydrogenase [KO:K11178] [EC:1.17.1.4]
NCTC10937_00907  hcrB_1; molybdopterin dehydrogenase [KO:K11178] [EC:1.17.1.4]
NCTC10937_03035  cutS_3; (2Fe-2S)-binding domain-containing protein [KO:K13483]
NCTC10937_02410  cutS_2; xanthine dehydrogenase iron-sulfur-binding subunit [KO:K13483]
NCTC10937_00906  cutS_1; 2Fe-2S iron-sulfur cluster binding domain-containing protein [KO:K13483]
NCTC10937_01377  guaA_1; ExsB family transcriptional regulator [KO:K01951] [EC:6.3.5.2]
NCTC10937_03755  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
NCTC10937_00193  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
NCTC10937_04067  nrdA; ribonucleotide-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
NCTC10937_04069  nrdB; ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
NCTC10937_02075  dgt; deoxyguanosinetriphosphate triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
NCTC10937_00195  spoT; RelA/SpoT protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
NCTC10937_05114  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
NCTC10937_04043  relA; GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
NCTC10937_00108  cyaA; adenylate cyclase [KO:K05851] [EC:4.6.1.1]
NCTC10937_00760  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
NCTC10937_04759  amn; protein Amn [KO:K01241] [EC:3.2.2.4]
NCTC10937_02850  ygdH; lysine decarboxylase [KO:K06966] [EC:3.2.2.10 3.2.2.-]
NCTC10937_04730  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
NCTC10937_01441  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
NCTC10937_04042  mazG; nucleoside triphosphate pyrophosphohydrolase MazG [KO:K04765] [EC:3.6.1.9]
NCTC10937_00555  cpdA_1; cAMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
NCTC10937_03044  cpdA_3; metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
NCTC10937_00730  cpdA_2; metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
NCTC10937_04940  apaH; bis(5'-nucleosyl)-tetraphosphatase, symmetrical [KO:K01525] [EC:3.6.1.41]
NCTC10937_01044  cysNC; bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
NCTC10937_01042  cysD; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
NCTC10937_02948  dihydropyrimidine dehydrogenase subunit A [KO:K22879] [EC:1.14.13.113]
NCTC10937_03760  pucM; transthyretin family protein [KO:K07127] [EC:3.5.2.17]
NCTC10937_03762  uraD; OHCU decarboxylase [KO:K13485] [EC:4.1.1.97]
NCTC10937_04455  Asp/Glu racemase [KO:K16841] [EC:5.1.99.3]
NCTC10937_03761  polysaccharide deacetylase [KO:K16842] [EC:3.5.2.5]
NCTC10937_03763  allantoicase [KO:K01477] [EC:3.5.3.4]
NCTC10937_03764  allA; ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
NCTC10937_02186  ureidoglycolate lyase [KO:K16856] [EC:4.3.2.3]
NCTC10937_00810  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
NCTC10937_00811  ureB; urease subunit beta [KO:K01429] [EC:3.5.1.5]
NCTC10937_00814  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
NCTC10937_02925  ywrD_4; gamma-glutamyltransferase [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
plg00030  Pentose phosphate pathway
plg00220  Arginine biosynthesis
plg00250  Alanine, aspartate and glutamate metabolism
plg00260  Glycine, serine and threonine metabolism
plg00340  Histidine metabolism
plg00630  Glyoxylate and dicarboxylate metabolism
plg00730  Thiamine metabolism
plg00740  Riboflavin metabolism
plg00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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