KEGG   PATHWAY: pswi00564
Entry
pswi00564                   Pathway                                
Name
Glycerophospholipid metabolism - Pseudoliparis swirei (Mariana hadal snailfish)
Class
Metabolism; Lipid metabolism
Pathway map
pswi00564  Glycerophospholipid metabolism
pswi00564

Module
pswi_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:pswi00564]
pswi_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:pswi00564]
pswi_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:pswi00564]
Other DBs
GO: 0006650
Organism
Pseudoliparis swirei (Mariana hadal snailfish) [GN:pswi]
Gene
130188202  phospho1; probable phosphatase phospho1 [KO:K06124] [EC:3.1.3.75]
130188484  pla2g10; group 10 secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
130188660  [KO:K00999] [EC:2.7.8.11]
130188666  cdipt; CDP-diacylglycerol--inositol 3-phosphatidyltransferase [KO:K00999] [EC:2.7.8.11]
130188902  ppap2d; phosphatidic acid phosphatase type 2D [KO:K01080] [EC:3.1.3.4]
130188979  [KO:K16342] [EC:3.1.1.4]
130189236  [KO:K00967] [EC:2.7.7.14]
130189482  [KO:K01080] [EC:3.1.3.4]
130189510  pcyt2; ethanolamine-phosphate cytidylyltransferase [KO:K00967] [EC:2.7.7.14]
130189716  pla2g6; 85/88 kDa calcium-independent phospholipase A2 [KO:K16343] [EC:3.1.1.4]
130189790  pnpla6; LOW QUALITY PROTEIN: patatin-like phospholipase domain-containing protein 6 [KO:K14676] [EC:3.1.1.5]
130190335  sgms2a; phosphatidylcholine:ceramide cholinephosphotransferase 2 [KO:K04714] [EC:2.7.8.27 2.7.8.48 3.1.4.62]
130190400  dgke; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
130190418  pla2g12a; group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
130190471  [KO:K01047] [EC:3.1.1.4]
130190918  [KO:K00968] [EC:2.7.7.15]
130191122  tafazzin; tafazzin isoform X1 [KO:K13511] [EC:2.3.1.-]
130191862  ptdss1b; phosphatidylserine synthase 1 [KO:K08729] [EC:2.7.8.-]
130191964  pld2; phospholipase D2 isoform X1 [KO:K01115] [EC:3.1.4.4]
130192842  lpin1a; phosphatidate phosphatase LPIN1 [KO:K15728] [EC:3.1.3.4]
130193112  lpcat2; lysophosphatidylcholine acyltransferase 2 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
130194399  [KO:K16342] [EC:3.1.1.4]
130194486  plpp3; phospholipid phosphatase 3 isoform X1 [KO:K01080] [EC:3.1.3.4]
130194523  lypla2; acyl-protein thioesterase 2 [KO:K06130] [EC:3.1.1.5]
130194779  chka; choline kinase alpha [KO:K14156] [EC:2.7.1.32 2.7.1.82]
130195031  dgkzb; diacylglycerol kinase zeta [KO:K00901] [EC:2.7.1.107]
130195073  ptdss2; phosphatidylserine synthase 2 [KO:K08730] [EC:2.7.8.29]
130195138  [KO:K00894] [EC:2.7.1.82]
130195937  lcat; phosphatidylcholine-sterol acyltransferase [KO:K00650] [EC:2.3.1.43]
130195938  pla2g15; group XV phospholipase A2 [KO:K06129] [EC:3.1.1.5]
130195966  chkb; choline/ethanolamine kinase [KO:K14156] [EC:2.7.1.32 2.7.1.82]
130196107  [KO:K01047] [EC:3.1.1.4]
130196287  [KO:K13506] [EC:2.3.1.15]
130196378  agpat9l; glycerol-3-phosphate acyltransferase 3-like [KO:K13506] [EC:2.3.1.15]
130196445  pla2g1b; phospholipase A2 [KO:K01047] [EC:3.1.1.4]
130196591  [KO:K01080] [EC:3.1.3.4]
130196844  cds2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
130197004  plpp5; phospholipid phosphatase 5 isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
130197183  gpat2; glycerol-3-phosphate acyltransferase 2, mitochondrial [KO:K00629] [EC:2.3.1.15]
130197304  cds1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
130197353  [KO:K14676] [EC:3.1.1.5]
130197398  [KO:K01047] [EC:3.1.1.4]
130197687  [KO:K00968] [EC:2.7.7.15]
130198038  [KO:K01080] [EC:3.1.3.4]
130198632  lpin2; phosphatidate phosphatase LPIN2 isoform X1 [KO:K15728] [EC:3.1.3.4]
130199764  dgkaa; diacylglycerol kinase, alpha a isoform X1 [KO:K00901] [EC:2.7.1.107]
130200162  [KO:K00006] [EC:1.1.1.8]
130200308  chpt1; cholinephosphotransferase 1 [KO:K00994] [EC:2.7.8.2]
130200362  etnk1; ethanolamine kinase 1 [KO:K00894] [EC:2.7.1.82]
130200453  dgki; diacylglycerol kinase iota isoform X1 [KO:K00901] [EC:2.7.1.107]
130201035  pld1a; phospholipase D1a isoform X1 [KO:K01115] [EC:3.1.4.4]
130201194  plpp2a; phospholipid phosphatase 2 isoform X1 [KO:K01080] [EC:3.1.3.4]
130201209  [KO:K16817] [EC:3.1.1.32 3.1.1.4]
130201210  [KO:K16817] [EC:3.1.1.32 3.1.1.4]
130201305  dgkh; diacylglycerol kinase eta isoform X1 [KO:K00901] [EC:2.7.1.107]
130201444  [KO:K14621] [EC:3.1.1.4 3.1.1.5]
130201568  [KO:K16860] [EC:3.1.4.4]
130201713  [KO:K16817] [EC:3.1.1.32 3.1.1.4]
130201789  lclat1; lysocardiolipin acyltransferase 1 isoform X1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
130201931  mboat2a; lysophospholipid acyltransferase 2 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
130202261  si:dkey-177p2.18; phospholipase B1, membrane-associated isoform X1 [KO:K14621] [EC:3.1.1.4 3.1.1.5]
130202386  lpgat1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 [KO:K13514] [EC:2.3.1.-]
130202432  lpin1b; phosphatidate phosphatase LPIN1 [KO:K15728] [EC:3.1.3.4]
130202433  gnpat2; dihydroxyacetone phosphate acyltransferase isoform X1 [KO:K00649] [EC:2.3.1.42]
130202487  gpcpd1; glycerophosphocholine phosphodiesterase GPCPD1 isoform X1 [KO:K18695] [EC:3.1.4.2]
130202944  gnpat; dihydroxyacetone phosphate acyltransferase isoform X1 [KO:K00649] [EC:2.3.1.42]
130203022  [KO:K14621] [EC:3.1.1.4 3.1.1.5]
130203214  adprm; manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
130203365  [KO:K00901] [EC:2.7.1.107]
130203368  [KO:K00995] [EC:2.7.8.5]
130203438  [KO:K22697] [EC:2.7.8.48 3.1.4.62]
130203465  gpam; glycerol-3-phosphate acyltransferase 1, mitochondrial [KO:K00629] [EC:2.3.1.15]
130203644  lpcat1; lysophosphatidylcholine acyltransferase 1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
130203826  pemt; phosphatidylethanolamine N-methyltransferase [KO:K00551] [EC:2.1.1.17 2.1.1.71]
130204040  [KO:K06124] [EC:3.1.3.75]
130204101  [KO:K00623] [EC:2.3.1.6]
130204106  agpat3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma [KO:K13523] [EC:2.3.1.51 2.3.1.-]
130204220  [KO:K00901] [EC:2.7.1.107]
130204474  [KO:K00006] [EC:1.1.1.8]
130204569  gpd2; glycerol-3-phosphate dehydrogenase, mitochondrial isoform X1 [KO:K00111] [EC:1.1.5.3]
130204895  [KO:K01047] [EC:3.1.1.4]
130205070  pla2g3; group 3 secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
130205265  pnpla7a; patatin-like phospholipase domain-containing protein 7a isoform X1 [KO:K14676] [EC:3.1.1.5]
130205270  agpat2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta isoform X1 [KO:K13509] [EC:2.3.1.51]
130205369  plpp1a; phospholipid phosphatase 1 isoform X1 [KO:K01080] [EC:3.1.3.4]
130205666  [KO:K01047] [EC:3.1.1.4]
130205691  gpat4; LOW QUALITY PROTEIN: glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
130205722  pisd; phosphatidylserine decarboxylase proenzyme, mitochondrial [KO:K01613] [EC:4.1.1.65]
130205941  pcyt1ba; choline-phosphate cytidylyltransferase B isoform X1 [KO:K00968] [EC:2.7.7.15]
130206061  pld1b; phospholipase D1 isoform X1 [KO:K01115] [EC:3.1.4.4]
130206146  lypla1; acyl-protein thioesterase 1 isoform X1 [KO:K06128] [EC:3.1.1.5]
130206182  [KO:K15728] [EC:3.1.3.4]
130207062  crls1; cardiolipin synthase (CMP-forming) [KO:K08744] [EC:2.7.8.41]
130207146  [KO:K00623] [EC:2.3.1.6]
130207266  plpp4; phospholipid phosphatase 4 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
130207307  sgms1a; phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1 [KO:K04714] [EC:2.7.8.27 2.7.8.48 3.1.4.62]
130207378  agpat5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon [KO:K19007] [EC:2.3.1.51]
130207424  pla2g12b; group XIIB secretory phospholipase A2-like protein [KO:K01047] [EC:3.1.1.4]
130207442  [KO:K22697] [EC:2.7.8.48 3.1.4.62]
130207552  pla2g4f.1; cytosolic phospholipase A2 zeta [KO:K16342] [EC:3.1.1.4]
130207553  [KO:K16342] [EC:3.1.1.4]
130207554  [KO:K16342] [EC:3.1.1.4]
130208298  cept1b; choline/ethanolaminephosphotransferase 1b isoform X1 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
130208337  [KO:K15728] [EC:3.1.3.4]
130208528  etnk2; ethanolamine kinase 2 isoform X1 [KO:K00894] [EC:2.7.1.82]
130208626  pla1a; phospholipase A1 member A [KO:K13618] [EC:3.1.1.111]
130208950  dgkab; diacylglycerol kinase, alpha b [KO:K00901] [EC:2.7.1.107]
130209078  [KO:K00006] [EC:1.1.1.8]
130209209  [KO:K16817] [EC:3.1.1.32 3.1.1.4]
130209343  pld7; uncharacterized protein pld7 isoform X1 [KO:K16860] [EC:3.1.4.4]
130209475  pmt; phosphoethanolamine methyltransferase isoform X1 [KO:K05929] [EC:2.1.1.103]
130209797  [KO:K00901] [EC:2.7.1.107]
130210414  proca1; uncharacterized protein proca1 [KO:K01047] [EC:3.1.1.4]
130211120  pld3; 5'-3' exonuclease PLD3 [KO:K16860] [EC:3.1.4.4]
130211561  lpcat4; lysophospholipid acyltransferase LPCAT4 isoform X1 [KO:K13512] [EC:2.3.1.23 2.3.1.-]
130211898  etnppl; ethanolamine-phosphate phospho-lyase isoform X1 [KO:K14286] [EC:4.2.3.2]
130211947  ache; acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
130212675  [KO:K13510] [EC:2.3.1.23 2.3.1.67]
130212700  dgkb; diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
130213287  ptdss1a; phosphatidylserine synthase 1 isoform X1 [KO:K08729] [EC:2.7.8.-]
130213397  mboat7; lysophospholipid acyltransferase 7 [KO:K13516] [EC:2.3.1.-]
130213460  lpcat3; lysophospholipid acyltransferase 5 isoform X1 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
130213512  mboat1; lysophospholipid acyltransferase 1 isoform X1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
pswi00010  Glycolysis / Gluconeogenesis
pswi00260  Glycine, serine and threonine metabolism
pswi00561  Glycerolipid metabolism
pswi00562  Inositol phosphate metabolism
pswi00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
pswi00565  Ether lipid metabolism
pswi00620  Pyruvate metabolism
KO pathway
ko00564   

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