KEGG   PATHWAY: rmuc00230
Entry
rmuc00230                   Pathway                                
Name
Purine metabolism - Roseomonas mucosa
Class
Metabolism; Nucleotide metabolism
Pathway map
rmuc00230  Purine metabolism
rmuc00230

Module
rmuc_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:rmuc00230]
rmuc_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:rmuc00230]
rmuc_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:rmuc00230]
rmuc_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:rmuc00230]
rmuc_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:rmuc00230]
rmuc_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:rmuc00230]
rmuc_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:rmuc00230]
Other DBs
GO: 0006163 0042278
Organism
Roseomonas mucosa [GN:rmuc]
Gene
FOB66_15795  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
FOB66_13495  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
FOB66_22535  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
FOB66_06435  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
FOB66_15955  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
FOB66_15925  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
FOB66_15935  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
FOB66_06440  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
FOB66_08295  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
FOB66_08300  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
FOB66_15085  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
FOB66_15920  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
FOB66_15905  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
FOB66_18335  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
FOB66_06230  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
FOB66_20385  bifunctional metallophosphatase/5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
FOB66_16015  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
FOB66_09835  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
FOB66_06425  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
FOB66_22600  non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
FOB66_11000  xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
FOB66_17565  2Fe-2S iron-sulfur cluster binding domain-containing protein [KO:K13481] [EC:1.17.1.4]
FOB66_17570  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
FOB66_03985  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
FOB66_20170  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
FOB66_03990  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
FOB66_20175  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
FOB66_03995  (2Fe-2S)-binding protein [KO:K13483]
FOB66_20180  paoA; aldehyde dehydrogenase iron-sulfur subunit [KO:K13483]
FOB66_09850  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
FOB66_07105  nucleoside deaminase [KO:K01487] [EC:3.5.4.3]
FOB66_13180  guanylate kinase [KO:K00942] [EC:2.7.4.8]
FOB66_07250  TSCPD domain-containing protein [KO:K00525] [EC:1.17.4.1]
FOB66_09865  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
FOB66_09870  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
FOB66_05950  dgt; dNTP triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
FOB66_10870  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
FOB66_10320  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
FOB66_06470  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
FOB66_09825  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
FOB66_12530  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
FOB66_06415  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
FOB66_18260  ade; adenine deaminase [KO:K01486] [EC:3.5.4.2]
FOB66_09435  adenine deaminase [KO:K01486] [EC:3.5.4.2]
FOB66_09920  adenine deaminase [KO:K01486] [EC:3.5.4.2]
FOB66_17155  bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
FOB66_12665  YmdB family metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
FOB66_15315  adenylate kinase [KO:K00939] [EC:2.7.4.3]
FOB66_10745  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
FOB66_02475  metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
FOB66_14640  NAD(P)/FAD-dependent oxidoreductase [KO:K22879] [EC:1.14.13.113]
FOB66_19190  NAD(P)/FAD-dependent oxidoreductase [KO:K22879] [EC:1.14.13.113]
FOB66_22505  NAD(P)/FAD-dependent oxidoreductase [KO:K22879] [EC:1.14.13.113]
FOB66_14635  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
FOB66_19495  Asp/Glu racemase [KO:K16841] [EC:5.1.99.3]
FOB66_14665  hydantoin racemase [KO:K16841] [EC:5.1.99.3]
FOB66_08000  amidohydrolase family protein [KO:K01466] [EC:3.5.2.5]
FOB66_12940  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
FOB66_02730  allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
FOB66_02335  (S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
FOB66_04335  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
FOB66_04330  urease subunit beta [KO:K01429] [EC:3.5.1.5]
FOB66_04325  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
rmuc00030  Pentose phosphate pathway
rmuc00220  Arginine biosynthesis
rmuc00250  Alanine, aspartate and glutamate metabolism
rmuc00260  Glycine, serine and threonine metabolism
rmuc00340  Histidine metabolism
rmuc00630  Glyoxylate and dicarboxylate metabolism
rmuc00730  Thiamine metabolism
rmuc00740  Riboflavin metabolism
rmuc00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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