KEGG   PATHWAY: ssn00230
Entry
ssn00230                    Pathway                                
Name
Purine metabolism - Shigella sonnei Ss046
Class
Metabolism; Nucleotide metabolism
Pathway map
ssn00230  Purine metabolism
ssn00230

Module
ssn_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:ssn00230]
ssn_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:ssn00230]
ssn_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ssn00230]
ssn_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:ssn00230]
ssn_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:ssn00230]
ssn_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:ssn00230]
Other DBs
GO: 0006163 0042278
Organism
Shigella sonnei Ss046 [GN:ssn]
Gene
SSON_0057  apaH; diadenosine tetraphosphatase [KO:K01525] [EC:3.6.1.41]
SSON_0112  guaC; GMP reductase [KO:K00364] [EC:1.7.1.7]
SSON_0133  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
SSON_0280  gpt; guanine-hypoxanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
SSON_0310  yahI; putative kinase [KO:K00926] [EC:2.7.2.2]
SSON_0367  yaiE; conserved hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
SSON_0456  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
SSON_0461  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
SSON_0464  gsk; inosine-guanosine kinase [KO:K00892] [EC:2.7.1.73]
SSON_0469  ushA; UDP-sugar hydrolase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
SSON_0495  purE; phosphoribosylaminoimidazole carboxylase [KO:K01588] [EC:5.4.99.18]
SSON_0496  purK; phosphoribosylaminoimidazole carboxylase [KO:K01589] [EC:6.3.4.18]
SSON_0497  arcC; putative carbamate kinase [KO:K00926] [EC:2.7.2.2]
SSON_0629  nagD; N-acetylglucosamine metabolism [KO:K02566] [EC:3.1.3.5]
SSON_0642  pgm; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
SSON_1149  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
SSON_1299  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
SSON_1535  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
SSON_1971  prsA; phosphoribosylpyrophosphate synthetase [KO:K00948] [EC:2.7.6.1]
SSON_2029  yedX; conserved hypothetical protein [KO:K07127] [EC:3.5.2.17]
SSON_2047  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
SSON_2293  nrdA; ribonucleoside diphosphate reductase 1, alpha subunit, B1 [KO:K00525] [EC:1.17.4.1]
SSON_2294  nrdB; ribonucleoside-diphosphate reductase 1, beta subunit, B2 [KO:K00526] [EC:1.17.4.1]
SSON_2348  [KO:K08722] [EC:3.1.3.89]
SSON_2370  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
SSON_2557  purC; phosphoribosylaminoimidazole-succinocarboxamide synthetase = SAICAR synthetase [KO:K01923] [EC:6.3.2.6]
SSON_2581  purM; phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
SSON_2582  purN; phosphoribosylglycinamide formyltransferase 1 [KO:K11175] [EC:2.1.2.2]
SSON_2584  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
SSON_2589  guaA; GMP synthetase [KO:K01951] [EC:6.3.5.2]
SSON_2590  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
SSON_2600  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
SSON_2640  purL; phosphoribosylformyl-glycineamide synthetase FGAM synthetase [KO:K01952] [EC:6.3.5.3]
SSON_2719  yfiH; conserved hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
SSON_2820  nrdE; ribonucleoside-diphosphate reductase 2 alpha subunit [KO:K00525] [EC:1.17.4.1]
SSON_2821  nrdF; ribonucleoside-diphosphate reductase 2, beta chain, frag [KO:K00526] [EC:1.17.4.1]
SSON_2892  surE; survival protein [KO:K03787] [EC:3.1.3.5 3.1.3.6]
SSON_2898  cysC; adenosine 5'-phosphosulfate kinase [KO:K00860] [EC:2.7.1.25]
SSON_2899  cysN; ATP-sulfurylase subunit 1 [KO:K00956] [EC:2.7.7.4]
SSON_2900  cysD; ATP-sulfurylase subunit 2 [KO:K00957] [EC:2.7.7.4]
SSON_2938  mazG; conserved hypothetical protein [KO:K04765] [EC:3.6.1.9]
SSON_2941  relA; (p)ppGpp synthetase I [KO:K00951] [EC:2.7.6.5]
SSON_2952  ygdH; conserved hypothetical protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
SSON_3017  [KO:K00087] [EC:1.17.1.4]
SSON_3018  ygeT; putative dehydrogenase [KO:K13479] [EC:1.17.1.4]
SSON_3019  [KO:K13480]
SSON_3025  yqeA; putative kinase [KO:K00926] [EC:2.7.2.2]
SSON_3108  yggV; putative ribosomal protein [KO:K01519] [EC:3.6.1.66]
SSON_3170  icc; regulator of lacZ [KO:K03651] [EC:3.1.4.53]
SSON_3172  yqiE; conserved hypothetical protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
SSON_3528  yrfE; conserved hypothetical protein [KO:K08312] [EC:3.6.1.-]
SSON_3530  yrfG; putative phosphatase [KO:K20881] [EC:3.1.3.-]
SSON_3619  yicP; probable adenine deaminase [KO:K01486] [EC:3.5.4.2]
SSON_3755  spoT; (p)ppGpp synthetase II [KO:K01139] [EC:2.7.6.5 3.1.7.2]
SSON_3757  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
SSON_3950  gppA; guanosine pentaphosphatase; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
SSON_3978  cyaA; adenylate cyclase [KO:K05851] [EC:4.6.1.1]
SSON_4178  purD; phosphoribosylglycinamide synthetase [KO:K01945] [EC:6.3.4.13]
SSON_4179  purH; phosphoribosylaminoimidazolecarboxamideformyltra nsferase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
SSON_4362  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
SSON_4398  cpdB; 2':3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
SSON_4419  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
SSON_4534  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
SSON_4535  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
SSON_4544  yjjX; conserved hypothetical protein [KO:K01529]
SSON_P147  ushA; UshA [KO:K11751] [EC:3.1.3.5 3.6.1.45]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
ssn00030  Pentose phosphate pathway
ssn00220  Arginine biosynthesis
ssn00250  Alanine, aspartate and glutamate metabolism
ssn00260  Glycine, serine and threonine metabolism
ssn00340  Histidine metabolism
ssn00630  Glyoxylate and dicarboxylate metabolism
ssn00730  Thiamine metabolism
ssn00740  Riboflavin metabolism
ssn00790  Folate biosynthesis
KO pathway
ko00230   

DBGET integrated database retrieval system