KEGG   PATHWAY: vvp04814
Entry
vvp04814                    Pathway                                
Name
Motor proteins - Vulpes vulpes (red fox)
Class
Cellular Processes; Cell motility
Pathway map
vvp04814  Motor proteins
vvp04814

Organism
Vulpes vulpes (red fox) [GN:vvp]
Gene
112907400  [KO:K07375]
112907410  [KO:K07375]
112907429  TUBAL3; tubulin alpha chain-like 3 [KO:K07374]
112907504  [KO:K07374]
112907570  [KO:K07374]
112907602  KIF4A; chromosome-associated kinesin KIF4A [KO:K10395]
112907895  WDR78; LOW QUALITY PROTEIN: WD repeat-containing protein 78 [KO:K24723]
112907900  TCTEX1D1; tctex1 domain-containing protein 1 [KO:K25421]
112907972  CAPZA1; F-actin-capping protein subunit alpha-1 [KO:K10364]
112908292  DCTN5; dynactin subunit 5 [KO:K10427]
112908367  CENPE; centromere-associated protein E [KO:K11498]
112908523  KIF3C; kinesin-like protein KIF3C isoform X1 [KO:K20197]
112908593  DNAH12; dynein heavy chain 12, axonemal [KO:K10408]
112908703  DNAL4; dynein light chain 4, axonemal [KO:K10412]
112909083  BICDL2; BICD family-like cargo adapter 2 isoform X1 [KO:K16756]
112909313  DNAH5; dynein heavy chain 5, axonemal [KO:K10408]
112909344  TNNI3; troponin I, cardiac muscle [KO:K12044]
112909381  TNNT1; troponin T, slow skeletal muscle [KO:K10372]
112909670  MYO1F; unconventional myosin-If [KO:K10356]
112910238  DYNLRB2; dynein light chain roadblock-type 2 [KO:K10419]
112910492  TNNC1; troponin C, slow skeletal and cardiac muscles isoform X1 [KO:K05865]
112910510  MYO1H; unconventional myosin-Ih [KO:K10356]
112910532  DNAH1; dynein heavy chain 1, axonemal isoform X1 [KO:K10408]
112910660  KIF18B; kinesin-like protein KIF18B [KO:K26156]
112910789  TUBG1; tubulin gamma-1 chain [KO:K10389]
112910811  [KO:K10389]
112911068  [KO:K07374]
112911170  KIFC2; kinesin-like protein KIFC2 [KO:K10406]
112911274  KIF1A; kinesin-like protein KIF1A isoform X1 [KO:K10392]
112911411  TUBB4B; tubulin beta-4B chain isoform X1 [KO:K07375]
112911627  KIF27; kinesin-like protein KIF27 [KO:K24186]
112911677  [KO:K10364]
112911687  MYL7; myosin regulatory light chain 2, atrial isoform [KO:K12754]
112911702  MYO1G; unconventional myosin-Ig [KO:K10356]
112911823  TUBB4A; LOW QUALITY PROTEIN: tubulin beta-4A chain [KO:K07375]
112912342  KIF9; kinesin-like protein KIF9 isoform X1 [KO:K10397]
112912851  [KO:K10357]
112913093  [KO:K09290]
112913119  MYO9B; unconventional myosin-IXb isoform X1 [KO:K10360]
112913137  TPM4; tropomyosin alpha-4 chain isoform X1 [KO:K10375]
112913164  KIF15; kinesin-like protein KIF15 [KO:K10400]
112913253  MYL3; myosin light chain 3 [KO:K12749]
112913571  TUBB; tubulin beta chain [KO:K07375]
112913662  KIF20B; kinesin-like protein KIF20B isoform X1 [KO:K10402]
112913681  MYH15; myosin-15 [KO:K24220]
112913768  [KO:K10393]
112913890  KIFC1; kinesin-like protein KIFC1 isoform X1 [KO:K10405]
112913962  KIF6; kinesin-like protein KIF6 [KO:K10397]
112914003  KLC4; kinesin light chain 4 [KO:K10407]
112914127  [KO:K10374]
112914208  DNAH8; dynein heavy chain 8, axonemal [KO:K10408]
112914663  DNALI1; axonemal dynein light intermediate polypeptide 1 [KO:K10410]
112914805  TCTEX1D4; tctex1 domain-containing protein 4 [KO:K25420]
112914808  KIF2C; kinesin-like protein KIF2C [KO:K10393]
112915185  ACTR1B; beta-centractin [KO:K16575]
112915203  DYNC2LI1; cytoplasmic dynein 2 light intermediate chain 1 isoform X1 [KO:K10417]
112915472  ACTR1A; alpha-centractin [KO:K16575]
112915812  DNAH11; LOW QUALITY PROTEIN: dynein heavy chain 11, axonemal [KO:K10408]
112916098  DCTN6; dynactin subunit 6 [KO:K10428]
112916166  HOOK3; protein Hook homolog 3 isoform X1 [KO:K16536]
112916319  [KO:K07374]
112916415  DYNC1I2; cytoplasmic dynein 1 intermediate chain 2 isoform X1 [KO:K10415]
112916565  MYO3B; myosin-IIIb [KO:K08834] [EC:2.7.11.1]
112916688  DNAH6; dynein heavy chain 6, axonemal [KO:K10408]
112916720  DCTN1; dynactin subunit 1 isoform X1 [KO:K04648]
112916733  ACTG2; actin, gamma-enteric smooth muscle [KO:K12315]
112917067  MYO5C; unconventional myosin-Vc [KO:K10357]
112917075  MYO5A; unconventional myosin-Va [KO:K10357]
112917077  KIF3A; kinesin-like protein KIF3A isoform X1 [KO:K10394]
112917444  TUBA8; tubulin alpha-8 chain [KO:K07374]
112917542  CAPZA3; F-actin-capping protein subunit alpha-3 [KO:K10364]
112917916  DYNLL2; dynein light chain 2, cytoplasmic [KO:K10418]
112917939  TUBD1; tubulin delta chain [KO:K10390]
112917958  MYO19; unconventional myosin-XIX isoform X1 [KO:K25838]
112918003  MYO1D; unconventional myosin-Id [KO:K10356]
112918138  KIF2B; kinesin-like protein KIF2B [KO:K10393]
112918704  MYL5; myosin light chain 5 [KO:K12753]
112918879  TPM3; tropomyosin alpha-3 chain isoform X1 [KO:K09290]
112919920  ACTC1; actin, alpha cardiac muscle 1 [KO:K12314]
112919990  STARD9; stAR-related lipid transfer protein 9 [KO:K16491]
112920518  KIF13A; kinesin-like protein KIF13A [KO:K17914]
112920591  MYL4; myosin light chain 4 [KO:K12750]
112920653  DNAI2; dynein intermediate chain 2, axonemal [KO:K11143]
112920713  [KO:K10375]
112920763  KIF19; kinesin-like protein KIF19 isoform X1 [KO:K26157]
112920795  MYO15B; myosin XVB [KO:K10361]
112920857  DNAH17; LOW QUALITY PROTEIN: dynein heavy chain 17, axonemal [KO:K10408]
112920888  ACTG1; LOW QUALITY PROTEIN: actin, cytoplasmic 2 [KO:K05692]
112921105  [KO:K07374]
112921106  TUBA1C; tubulin alpha-1C chain [KO:K07374]
112921195  KIF21A; kinesin-like protein KIF21A [KO:K24185]
112921338  MYO1E; unconventional myosin-Ie [KO:K10356]
112921387  ACTR10; actin-related protein 10 [KO:K16576]
112921588  KIF5B; kinesin-1 heavy chain [KO:K10396]
112921599  DYNC1LI1; cytoplasmic dynein 1 light intermediate chain 1 [KO:K10416]
112921668  KIF7; LOW QUALITY PROTEIN: kinesin-like protein KIF7 [KO:K18806]
112921961  KIF20A; kinesin-like protein KIF20A [KO:K10402]
112922341  KIF5A; kinesin heavy chain isoform X1 [KO:K10396]
112922343  DCTN2; dynactin subunit 2 isoform X1 [KO:K10424]
112922362  MYO1A; unconventional myosin-Ia [KO:K10356]
112922390  MYL6; myosin light polypeptide 6 isoform X1 [KO:K12751]
112922391  MYL6B; myosin light chain 6B [KO:K12751]
112922521  [KO:K07374]
112922524  [KO:K07374]
112922591  MYL1; myosin light chain 1/3, skeletal muscle isoform isoform X1 [KO:K05738]
112922739  KIF16B; kinesin-like protein KIF16B isoform X1 [KO:K17916]
112922812  DNAH7; dynein heavy chain 7, axonemal [KO:K10408]
112922859  TPM1; tropomyosin alpha-1 chain isoform X1 [KO:K10373]
112922918  MYO1B; unconventional myosin-Ib isoform X1 [KO:K10356]
112923087  KIF12; kinesin-like protein KIF12 isoform X1 [KO:K10399]
112923198  MYO18B; unconventional myosin-XVIIIb [KO:K10362]
112923351  MYH11; myosin-11 isoform X1 [KO:K10352]
112923392  DNAH3; dynein heavy chain 3, axonemal [KO:K10408]
112923428  [KO:K10404]
112923438  DNAH14; LOW QUALITY PROTEIN: dynein heavy chain 14, axonemal [KO:K10408]
112923477  KIFAP3; kinesin-associated protein 3 isoform X1 [KO:K25388]
112923907  DYNC1I1; cytoplasmic dynein 1 intermediate chain 1 isoform X1 [KO:K10415]
112923957  TNNI2; troponin I, fast skeletal muscle [KO:K12043]
112923958  TNNT3; troponin T, fast skeletal muscle isoform X1 [KO:K12046]
112924226  KLC2; kinesin light chain 2 [KO:K10407]
112924488  WDR63; WD repeat-containing protein 63 [KO:K24722]
112924650  TUBB3; tubulin beta-3 chain [KO:K07375]
112924657  KIF1B; kinesin-like protein KIF1B isoform X1 [KO:K10392]
112924745  [KO:K24220]
112924784  KIF1C; kinesin-like protein KIF1C [KO:K10392]
112924856  DNAH2; dynein heavy chain 2, axonemal isoform X1 [KO:K10408]
112924883  MYH10; myosin-10 isoform X1 [KO:K10352]
112924895  [KO:K24220]
112924896  MYH8; myosin-8 isoform X1 [KO:K24220]
112924897  [KO:K24220]
112924899  [KO:K24220]
112924900  [KO:K24220]
112924905  DNAH9; dynein heavy chain 9, axonemal [KO:K10408]
112925014  MYO15A; unconventional myosin-XV [KO:K10361]
112925071  MYO10; unconventional myosin-X [KO:K12559]
112925188  TUBE1; tubulin epsilon chain isoform X1 [KO:K10391]
112925208  TCTE3; tctex1 domain-containing protein 3 [KO:K25419]
112925250  MYO5B; unconventional myosin-Vb [KO:K10357]
112925264  [KO:K12757]
112925265  [KO:K12757]
112925302  TUBB6; tubulin beta-6 chain [KO:K07375]
112925909  DYNC2H1; cytoplasmic dynein 2 heavy chain 1 [KO:K10414]
112926370  MYO6; unconventional myosin-VI isoform X1 [KO:K10358]
112926472  [KO:K17751]
112926516  [KO:K17751]
112926740  KIF13B; kinesin-like protein KIF13B [KO:K17914]
112926866  KIF5C; kinesin heavy chain [KO:K10396]
112927192  DCTN4; dynactin subunit 4 isoform X1 [KO:K10426]
112927254  DNAL1; dynein light chain 1, axonemal [KO:K10411]
112927392  ACTA1; actin, alpha skeletal muscle [KO:K10354]
112927498  MYO16; unconventional myosin-XVI [KO:K17481]
112927533  DCTN3; dynactin subunit 3 [KO:K10425]
112927537  DNAI1; dynein intermediate chain 1, axonemal [KO:K10409]
112927544  KIF24; kinesin-like protein KIF24 [KO:K10393]
112927962  KIF11; kinesin-like protein KIF11 [KO:K10398]
112928190  MYL9; myosin regulatory light polypeptide 9 [KO:K12755]
112928222  MYH7B; myosin-7B isoform X1 [KO:K24220]
112928233  DYNLRB1; dynein light chain roadblock-type 1 isoform X1 [KO:K10419]
112928258  KIF3B; kinesin-like protein KIF3B [KO:K20196]
112928623  MYO7A; unconventional myosin-VIIa [KO:K10359]
112929085  MYH9; myosin-9 isoform X1 [KO:K10352]
112929326  ACTB; LOW QUALITY PROTEIN: actin, cytoplasmic 1 [KO:K05692]
112929343  KIF22; kinesin-like protein KIF22 [KO:K10403]
112929344  MYLPF; myosin regulatory light chain 2, skeletal muscle isoform [KO:K12758]
112929354  [KO:K26157]
112929390  DYNC1LI2; cytoplasmic dynein 1 light intermediate chain 2 [KO:K10416]
112929654  KIFC3; kinesin-like protein KIFC3 isoform X1 [KO:K10406]
112929814  CAPZB; F-actin-capping protein subunit beta isoform X1 [KO:K10365]
112929827  KIF17; kinesin-like protein KIF17 isoform X1 [KO:K20198]
112929898  CAPZA2; F-actin-capping protein subunit alpha-2 [KO:K10364]
112929941  DYNLT3; dynein light chain Tctex-type 3 [KO:K10420]
112930254  KIF26A; kinesin-like protein KIF26A [KO:K10404]
112930275  DYNC1H1; cytoplasmic dynein 1 heavy chain 1 [KO:K10413]
112930295  KLC1; kinesin light chain 1 isoform X1 [KO:K10407]
112930822  TPM2; tropomyosin beta chain isoform X1 [KO:K10374]
112931122  MYO3A; myosin-IIIa [KO:K08834] [EC:2.7.11.1]
112931259  KLC3; kinesin light chain 3 isoform X1 [KO:K10407]
112931466  MYH14; myosin-14 isoform X1 [KO:K10352]
112931912  TNNC2; troponin C, skeletal muscle [KO:K12042]
112931966  ACTA2; actin, aortic smooth muscle [KO:K12313]
112932261  TUBB1; tubulin beta-1 chain [KO:K07375]
112932733  MYO7B; unconventional myosin-VIIb [KO:K21868]
112932886  DYNLL1; dynein light chain 1, cytoplasmic [KO:K10418]
112932891  BICDL1; BICD family-like cargo adapter 1 isoform X1 [KO:K16756]
112932966  KIF25; kinesin-like protein KIF25 [KO:K18627]
112933060  MYO1C; unconventional myosin-Ic isoform X1 [KO:K10356]
112933164  MYO18A; unconventional myosin-XVIIIa isoform X1 [KO:K10362]
112933463  MYO9A; unconventional myosin-IXa isoform X1 [KO:K10360]
112933821  DNAH10; dynein heavy chain 10, axonemal [KO:K10408]
112934536  TNNT2; troponin T, cardiac muscle isoform X1 [KO:K12045]
112934540  KIF14; kinesin-like protein KIF14 [KO:K17915]
112934542  TNNI1; troponin I, slow skeletal muscle [KO:K10371]
112934546  [KO:K07374]
112934578  KIF21B; kinesin-like protein KIF21B isoform X1 [KO:K24185]
112935034  KIF18A; kinesin-like protein KIF18A [KO:K10401]
112935156  DYNLT1; dynein light chain Tctex-type 1 [KO:K10420]
112935243  MYL2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform [KO:K10351]
112935472  KIF2A; kinesin-like protein KIF2A [KO:K10393]
112935732  MYL10; myosin regulatory light chain 10 [KO:K12756]
Reference
PMID:21092854
  Authors
Hirokawa N, Niwa S, Tanaka Y
  Title
Molecular motors in neurons: transport mechanisms and roles in brain function, development, and disease.
  Journal
Neuron 68:610-38 (2010)
DOI:10.1016/j.neuron.2010.09.039
Reference
PMID:25470043 (PDB:4RH7)
  Authors
Schmidt H, Zalyte R, Urnavicius L, Carter AP
  Title
Structure of human cytoplasmic dynein-2 primed for its power stroke.
  Journal
Nature 518:435-438 (2015)
DOI:10.1038/nature14023
Reference
PMID:22398446 (PDB:3VKG 3VKH)
  Authors
Kon T, Oyama T, Shimo-Kon R, Imamula K, Shima T, Sutoh K, Kurisu G
  Title
The 2.8 A crystal structure of the dynein motor domain.
  Journal
Nature 484:345-50 (2012)
DOI:10.1038/nature10955
Reference
PMID:22997337 (PDB:3J1T 3J1U)
  Authors
Redwine WB, Hernandez-Lopez R, Zou S, Huang J, Reck-Peterson SL, Leschziner AE
  Title
Structural basis for microtubule binding and release by dynein.
  Journal
Science 337:1532-1536 (2012)
DOI:10.1126/science.1224151
Reference
PMID:26410600
  Authors
Gibbs KL, Greensmith L, Schiavo G
  Title
Regulation of Axonal Transport by Protein Kinases.
  Journal
Trends Biochem Sci 40:597-610 (2015)
DOI:10.1016/j.tibs.2015.08.003
Reference
PMID:28602352 (PDB:5NUG 5NVS 5NVU 5NW4)
  Authors
Zhang K, Foster HE, Rondelet A, Lacey SE, Bahi-Buisson N, Bird AW, Carter AP
  Title
Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated.
  Journal
Cell 169:1303-1314.e18 (2017)
DOI:10.1016/j.cell.2017.05.025
Reference
PMID:25814576 (PDB:5ADX 5AFR 5AFU)
  Authors
Urnavicius L, Zhang K, Diamant AG, Motz C, Schlager MA, Yu M, Patel NA, Robinson CV, Carter AP
  Title
The structure of the dynactin complex and its interaction with dynein.
  Journal
Science 347:1441-1446 (2015)
DOI:10.1126/science.aaa4080
Reference
PMID:29420470 (PDB:5OWO 6F1T 6F1U 6F1V 6F1Y 6F1Z 6F38 6F3A)
  Authors
Urnavicius L, Lau CK, Elshenawy MM, Morales-Rios E, Motz C, Yildiz A, Carter AP
  Title
Cryo-EM shows how dynactin recruits two dyneins for faster movement.
  Journal
Nature 554:202-206 (2018)
DOI:10.1038/nature25462
Reference
PMID:29662141
  Authors
Reck-Peterson SL, Redwine WB, Vale RD, Carter AP
  Title
The cytoplasmic dynein transport machinery and its many cargoes.
  Journal
Nat Rev Mol Cell Biol 19:382-398 (2018)
DOI:10.1038/s41580-018-0004-3
Reference
PMID:23434508 (PDB:3J2U)
  Authors
Asenjo AB, Chatterjee C, Tan D, DePaoli V, Rice WJ, Diaz-Avalos R, Silvestry M, Sosa H
  Title
Structural model for tubulin recognition and deformation by kinesin-13 microtubule depolymerases.
  Journal
Cell Rep 3:759-68 (2013)
DOI:10.1016/j.celrep.2013.01.030
Reference
PMID:10338210 (PDB:1B7T)
  Authors
Houdusse A, Kalabokis VN, Himmel D, Szent-Gyorgyi AG, Cohen C
  Title
Atomic structure of scallop myosin subfragment S1 complexed with MgADP: a novel conformation of the myosin head.
  Journal
Cell 97:459-70 (1999)
DOI:10.1016/s0092-8674(00)80756-4
Reference
PMID:9428521 (PDB:3KIN)
  Authors
Kozielski F, Sack S, Marx A, Thormahlen M, Schonbrunn E, Biou V, Thompson A, Mandelkow EM, Mandelkow E
  Title
The crystal structure of dimeric kinesin and implications for microtubule-dependent motility.
  Journal
Cell 91:985-94 (1997)
DOI:10.1016/s0092-8674(00)80489-4
Reference
PMID:8316857 (PDB:2MYS)
  Authors
Rayment I, Rypniewski WR, Schmidt-Base K, Smith R, Tomchick DR, Benning MM, Winkelmann DA, Wesenberg G, Holden HM
  Title
Three-dimensional structure of myosin subfragment-1: a molecular motor.
  Journal
Science 261:50-8 (1993)
DOI:10.1126/science.8316857
Reference
PMID:20428469
  Authors
Parker D, Bryant Z, Delp SL
  Title
Coarse-Grained Structural Modeling of Molecular Motors Using Multibody Dynamics.
  Journal
Cell Mol Bioeng 2:366-374 (2009)
DOI:10.1007/s12195-009-0084-4
Reference
PMID:21314430
  Authors
Dominguez R, Holmes KC
  Title
Actin structure and function.
  Journal
Annu Rev Biophys 40:169-86 (2011)
DOI:10.1146/annurev-biophys-042910-155359
Reference
PMID:31919429 (PDB:6KN7 6KN8)
  Authors
Yamada Y, Namba K, Fujii T
  Title
Cardiac muscle thin filament structures reveal calcium regulatory mechanism.
  Journal
Nat Commun 11:153 (2020)
DOI:10.1038/s41467-019-14008-1
Reference
PMID:33912943
  Authors
Kruppa AJ, Buss F
  Title
Motor proteins at the mitochondria-cytoskeleton interface.
  Journal
J Cell Sci 134:239092 (2021)
DOI:10.1242/jcs.226084
KO pathway
ko04814   

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