 Eukaryotic type
|
Basic leucine zipper (bZIP)
|
 AP-1(-like) components, Jun
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AP-1(-like) components, Fos
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AP-1(-like) components, Maf
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AP-1(-like) components, NF-E2
|
 K09039 NFE2; nuclear factor erythroid 2
K09040 NFE2L1_3; nuclear factor erythroid 2-related factor 1/3
K05638 NFE2L2, NRF2; nuclear factor erythroid 2-related factor 2
K09041 NFE2N, CNC; nuclear factor erythroid 2, invertebrate
K09042 BACH; transcription regulator BACH
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AP-1(-like) components, Fungal regulators
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AP-1(-like) components, CRE-BP/ATF
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CREB
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C/EBP-like factors
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bZIP/PAR
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Plant bZIP factors
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ZIP only
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Basic helix-loop-helix (bHLH)
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Ubiquitous (class A) factors
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Myogenic transcription factors
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Achaete-Scute
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Tal/Twist/Atonal/Hen, Lymphoid factors
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Tal/Twist/Atonal/Hen, Mesodermal Twist-like factors
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Tal/Twist/Atonal/Hen, HEN
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Tal/Twist/Atonal/Hen, Mesp
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Tal/Twist/Atonal/Hen, Atonal
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Tal/Twist/Atonal/Hen, Pancreatic factors
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Hairy, Hairy/E(SPL)
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K06054 HES1; hairy and enhancer of split 1
K09087 HES2_6_7; hairy and enhancer of split 2/6/7
K09088 HES3; hairy and enhancer of split 3
K09089 HES4; hairy and enhancer of split 4
K06055 HES5; hairy and enhancer of split 5
K09090 HESN; hairy and enhancer of split, invertebrate
K09091 HEY; hairy and enhancer of split related with YRPW motif
K03729 BHLHB2, DEC1; class B basic helix-loop-helix protein 2
K03730 BHLHB3, DEC2; class B basic helix-loop-helix protein 3
K09092 TCFL5, CHA; transcription factor-like 5
K27237 CWO; transcription factor CWO
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Hairy, Fungal regulators
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Factors with PAS domain
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Yabby
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INO
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HLH domain only
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Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
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Other basic domains
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Zinc finger
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Cys4 thyroid hormone receptor-like
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K05547 THRA, NR1A1; thyroid hormone receptor alpha
K08362 THRB, NR1A2; thyroid hormone receptor beta
K08527 RARA, NR1B1; retinoic acid receptor alpha
K08528 RARB, NR1B2; retinoic acid receptor beta
K08529 RARG, NR1B3; retinoic acid receptor gamma
K07294 NR1C1, PPARA; peroxisome proliferator-activated receptor alpha
K04504 NR1C2, PPARD; peroxisome proliferator-activated receptor delta
K08530 NR1C3, PPARG; peroxisome proliferator-activated receptor gamma
K03728 NR1D1; nuclear receptor subfamily 1 group D member 1
K08531 NR1D2; nuclear receptor subfamily 1 group D member 2
K08701 NR1D3; nuclear receptor subfamily 1 group D member 3
K08532 NR1F1, RORA; RAR-related orphan receptor alpha
K08533 NR1F2, RORB; RAR-related orphan receptor beta
K08534 NR1F3, RORC; RAR-related orphan receptor gamma
K14033 NR1F4; nuclear receptor subfamily 1 group F member 4
K08536 NR1H3, LXRA; liver X receptor alpha
K08535 NR1H2, LXRB; liver X receptor beta
K08537 NR1H4, FXR; farnesoid X receptor
K08538 NR1H5, FXRB; farnesoid X receptor beta
K14034 NR1H1, EcR; ecdysone receptor
K08539 VDR, NR1I1; vitamin D3 receptor
K08540 NR1I2, PXR; pregnane X receptor
K08541 NR1I3, CAR; constitutive androstane receptor
K14035 NR1IN; nuclear receptor subfamily 1 group I
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Cys4 hepatocyte nuclear factor 4-like
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Cys4 estrogen receptor-like
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K08550 ESR1, NR3A1; estrogen receptor alpha
K08551 ESR2, NR3A2; estrogen receptor beta
K08552 NR3B1, ESRRA; estrogen-related receptor alpha
K08553 NR3B2, ESRRB; estrogen-related receptor beta
K08554 NR3B3, ESRRG; estrogen-related receptor gamma
K08703 NR3BN, ERR; estrogen-related receptor ERR
K05771 NR3C1, GR; glucocorticoid receptor
K08555 NR3C2, MR; mineralocorticoid receptor
K08556 PGR, NR3C3; progesterone receptor
K08557 AR, NR3C4; androgen receptor
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Cys4 nerve growth factor IB-like
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Cys4 Fushi tarazu-F1-like
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Cys4 germ cell nuclear factor
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Cys4 Knirps/DAX1-like
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Cys4 GATA-factors
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Cys2His2 SP/KLF family and related proteins
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K04684 SP1; transcription factor Sp1
K09192 SP2; transcription factor Sp2
K09193 SP3; transcription factor Sp3
K09194 SP4; transcription factor Sp4
K09195 SP5; transcription factor Sp5
K09196 SP6; transcription factor Sp6
K09197 SP7; transcription factor Sp7
K09198 SP8; transcription factor Sp8
K09199 SP9; transcription factor Sp9
K09200 SP-N; transcription factor Sp, invertebrate
K09204 KLF1; krueppel-like factor 1
K17845 KLF2; krueppel-like factor 2
K15605 KLF3; krueppel-like factor 3
K17846 KLF4; krueppel-like factor 4
K09206 KLF5; krueppel-like factor 5
K09207 KLF6_7; krueppel-like factor 6/7
K09205 KLF8_12; krueppel-like factor 8/12
K09208 KLF9S, BTEB; krueppel-like factor 9/13/14/16
K09209 KLF10_11, TIEG; krueppel-like factor 10/11
K09210 KLF15; krueppel-like factor 15
K09211 KLF17; krueppel-like factor 17
K09203 EGR1; early growth response protein 1
K12496 EGR2; early growth response protein 2
K12497 EGR3; early growth response protein 3
K12498 EGR4; early growth response protein 4
K09202 SWI5; regulatory protein SWI5
K09234 WT1; Wilms tumor protein 1
K27541 ZFX_Y; zinc finger X/Y-chromosomal protein
K12379 HKB; huckebein
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Cys2His2 GLI-like
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Cys2His2 Snail
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Cys2His2 BTB-ZF factors
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Cys2His2 BED
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Cys2His2 PRDM
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Cys2His2 metabolic regulators in fungi
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Cys2His2 others
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Cys2HisCys zinc factors
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Cys3His zinc factors
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Cys2CysHis zinc factors
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CXXC CpG-binding proteins
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Cys6 metabolic regulators in fungi
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Other zinc fingers
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Helix-turn-helix
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Homeo domain ANTP: HOXL
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K21950 HOXA9; homeobox protein Hox-A9
K09294 HOX_9; homeobox protein HoxB/C/D9
K17443 HOXA10; homrobox protein Hox-A10
K17444 HOXC10; homrobox protein Hox-C10
K09295 HOXD10; homrobox protein Hox-D10
K21951 HOXA11; homeobox protein Hox-A11
K09296 HOX_11; homeobox protein HoxC/D11
K09297 HOX_12; homeobox protein HoxC/D12
K09298 HOX_13; homeobox protein HoxA/B/C/D13
K09301 HOX_1; homeobox protein HoxA/B/D1
K09302 HOX_2; homeobox protein HoxA/B2
K09303 HOX_3; homeobox protein HoxA/B/D3
K09304 HOX_4; homeobox protein HoxA/B/C/D4
K09305 HOX_5; homeobox protein HoxA/B/C5
K09306 HOX_6; homeobox protein HoxA/B/C6
K09307 HOX_7; homeobox protein HoxA/B7
K09308 HOX_8; homeobox protein HoxB/C/D8
K09310 GSH; homeobox protein GSH
K07594 IPF1, PDX1; insulin promoter factor 1
K09312 CDX1_4; homeobox protein CDX1/4
K22234 CDX2; homeobox protein CDX2
K09320 EVX; homeobox even-skipped homolog protein
K09321 GBX; homeobox protein GBX
K08025 HLXB9, HB9; homeobox protein HB9
K09322 MEOX, MOX; homeobox protein MOX
K09300 ABDB; homeobox protein abdominal-B and related proteins
K18659 BCD; homeotic protein bicoid
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Homeo domain ANTP: NKL
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Homeo domain Paired-related
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K09452 ARX; homeobox protein aristaless-related
K09323 ALX3; homeobox protein aristaless-like 3
K09451 ALX4; homeobox protein aristaless-like 4
K09324 GSC; homeobox protein goosecoid
K09325 GSCL; homeobox protein goosecoid-like
K09326 OTX1; homeobox protein OTX1
K18490 OTX2; homeobox protein OTX2
K09327 PROP1; homeobox protein prophet of Pit-1
K09328 UNC4; homeobox protein Unc-4
K09329 PRRX, PMX; paired mesoderm homeobox protein
K09330 PHOX2, PMX2; paired mesoderm homeobox protein 2
K09331 SHOX; short stature homeobox protein
K09332 RAX, RX; retina and anterior neural fold homeobox protein
K09333 RAXL; retina and anterior neural fold homeobox-like protein
K09334 ALX1, CART1; ALX homeobox protein 1
K09335 VSX1; visual system homeobox protein 1
K09336 VSX2, CHX10; visual system homeobox protein 2
K09337 CRX; cone-rod homeobox protein
K18491 ESX1; homeobox protein ESX1
K24199 NOBOX; homeobox protein NOBOX
K09356 PITX1; paired-like homeodomain transcription factor 1
K04686 PITX2; paired-like homeodomain transcription factor 2
K09357 PITX3; paired-like homeodomain transcription factor 3
K09354 HESX1; homeobox protein expressed in ES cells 1
K24892 ARGFX; arginine-fifty homeobox
K24893 DMBX1; diencephalon/mesencephalon homeobox protein 1
K24894 DPRX; divergent paired-related homeobox
K24895 DRGX, PRRXL1; dorsal root ganglia homeobox protein
K24896 DUX; double homeobox protein
K24897 HOPX; homeodomain-only protein
K24898 ISX; intestine-specific homeobox
K24899 LEUTX; leucine-twenty homeobox
K24900 MIXL1; homeobox protein MIXL1
K24901 OTP; homeobox protein orthopedia
K24902 RHOXF1; rhox homeobox family member 1
K24903 RHOXF2; rhox homeobox family member 2
K24904 SEBOX; homeobox protein SEBOX
K24905 TPRX1; tetra-peptide repeat homeobox protein 1
K09382 PAX1_9; paired box protein 1/9
K15608 PAX2; paired box protein 2
K09381 PAX3_7; paired box protein 3/7
K08032 PAX4; paired box protein 4
K09383 PAX5; paired box protein 5
K08031 PAX6; paired box protein 6
K09293 PAX8; paired box protein 8
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Homeo domain LIM
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Homeo domain POU
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Homeo domain SINE
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Homeo domain ZF
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Homeo domain CUT
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Homeo domain PROS
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Homeo domain TALE
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Homeo domain other
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Fork head/winged helix developmental regulators
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Fork head/winged helix tissue-specific regulators
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Fork head/winged helix cell cycle-controlling factors, E2F
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Fork head/winged helix cell cycle-controlling factors, DP
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Fork head/winged helix other regulators
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Stork head/winged helix factors
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Heat shock factors
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Tryptophan clusters Myb, Myb-factors
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K09420 MYB, C-MYB; transcriptional activator Myb
K09421 MYBL1, A-MYB; myb-related protein A
K21769 MYBL2, B-MYB; myb-related protein B
K09422 MYBP; transcription factor MYB, plant
K23865 MYB30; transcription factor MYB30
K16166 PAP1, MYB75; transcription factor MYB75
K12133 LHY; MYB-related transcription factor LHY
K12134 CCA1; circadian clock associated 1
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Tryptophan clusters Myb, Myb-like factors
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Tryptophan clusters Ets-type
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Tryptophan clusters interferon-regulating factors
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TEA domain
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ARID
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beta-Scaffold factors with minor groove contacts
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RHR (Rel homology region) Rel/Ankyrin
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K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
K04469 NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2
K04735 RELA; transcription factor p65
K09253 RELB; transcription factor RelB
K09254 REL; c-Rel proto-oncogene protein
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RHR (Rel homology region) Ankyrin only
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RHR (Rel homology region) NF-AT
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STAT
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p53
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MADS-box regulators of differentiation, MEF-2
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MADS-box regulators of differentiation, Homeotic genes
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MADS-box regulators of differentiation, Yeast regulators
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MADS-box responders to external signals
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SAND domain-containing proteins
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TATA-binding proteins
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HMG SOX
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HMG TCF-1
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HMG TOX
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K28489 TOX; thymocyte selection-associated high mobility group box protein
K11651 SMARCE1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
K24660 HMG20A; high mobility group protein 20A
K24650 HMG20B; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related
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HMG2-related
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K09272 SSRP1, POB3; FACT complex subunit SSRP1/POB3
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UBF
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Other HMG box factors
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Heteromeric CCAAT factors
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Grainyhead
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K09275 TFCP2; transcription factor CP2 and related proteins
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Cold-shock domain factors, DbpA-like
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Cold-shock domain factors, YB-1/DbpB-like
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Cold-shock domain factors, FRG Y2-like
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Runt
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K08367 RUNX1, AML1; runt-related transcription factor 1
K09278 RUNX2, AML3; runt-related transcription factor 2
K09279 RUNX3, AML2; runt-related transcription factor 3
K20213 RUN; RUNX transcription factor Runt
K20214 LZ; RUNX transcription factor Lozenge
K09280 RUNXA_B; runt-related transcription factor
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MYRF
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Other transcription factors
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HMGI(Y)
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NUPR
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Pocket domain Rb
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Pocket domain CBP
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T-box
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DMRT
|
K19488 DMRT1; doublesex- and mab-3-related transcription factor 1
K19489 DMRT2; doublesex- and mab-3-related transcription factor 2
K19490 DMRT3; doublesex- and mab-3-related transcription factor 3
K19491 DMRT4_5, DMRTA; doublesex- and mab-3-related transcription factor 4/5
K19492 DMRT6, DMRTB; doublesex- and mab-3-related transcription factor 6
K19493 DMRT7, DMRTC2; doublesex- and mab-3-related transcription factor 7
K19494 DMRT8, DMRTC1; doublesex- and mab-3-related transcription factor 8
|
LRRFIP
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TCP
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AP2/ERF
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K09284 AP2; AP2-like factor, euAP2 lineage
K09285 OVM, ANT; AP2-like factor, ANT lineage
K09287 RAV; RAV-like factor
K09286 EREBP; EREBP-like factor
K14516 ERF1; ethylene-responsive transcription factor 1
K14517 ERF2; ethylene-responsive transcription factor 2
K14507 ORCA2_3; AP2-domain DNA-binding protein ORCA2/3
K13432 PTI4; pathogenesis-related genes transcriptional activator PTI4
K13433 PTI5; pathogenesis-related genes transcriptional activator PTI5
K13434 PTI6; pathogenesis-related genes transcriptional activator PTI6
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WRKY
|
LOB
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GRAS
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NAC
|
Copper-fist proteins fungal regulators
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Others
|
|
Prokaryotic type
|
Helix-turn-helix
|
AraC family
|
LysR family
|
DeoR family
|
LacI family
|
GntR family
|
TetR/AcrR family
|
Lrp/AsnC family
|
LuxR family
|
MarR family
|
MerR family
|
Fur family
|
IclR family
|
CRP/FNR family
|
Rrf2 family
|
ArsR family
|
XRE family
|
PadR family
|
Other families
|
K26252 dtxR, ideR; DtxR family transcriptional regulator, iron-dependent repressor
K03709 troR, sirR, scaR, mntR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
K11924 mntR; DtxR family transcriptional regulator, manganese transport regulator
K23238 rpiR, alsR; RpiR family transcriptional regulator, repressor of rpiB and als operon
K03481 glvR; RpiR family transcriptional regulator, glv operon transcriptional regulator
K15835 murR; RpiR family transcriptional regulator, murPQ operon repressor
K19337 hexR; RpiR family transcriptional regulator, carbohydrate utilization regulator
K02171 blaI; BlaI family transcriptional regulator, penicillinase repressor
K02546 mecI; BlaI family transcriptional regulator, methicillin resistance regulatory protein
K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
K03720 trpR; TrpR family transcriptional regulator, trp operon repressor
K02688 prpR; transcriptional regulator, propionate catabolism operon regulatory protein
K07724 ner, nlp, sfsB; Ner family transcriptional regulator
K11925 sgrR; SgrR family transcriptional regulator
K06211 nadR; HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes [EC:2.7.7.1 2.7.1.22]
K13655 mqsA; HTH-type transcriptional regulator / antitoxin MqsA
K14056 puuR; HTH-type transcriptional regulator, repressor for puuD
K15773 hipB; HTH-type transcriptional regulator / antitoxin HipB
K18830 pezA; HTH-type transcriptional regulator / antitoxin PezA
K20480 nprR, nprA; HTH-type transcriptional regulator, quorum sensing regulator NprR
K20342 comR; HTH-type transcriptional regulator, regulator for ComX
K20373 rgg2; HTH-type transcriptional regulator, SHP2-responsive activator
K20374 rgg3; HTH-type transcriptional regulator, SHP3-responsive repressor
K22299 rghR; HTH-type transcriptional regulator, competence development regulator
K22300 dicA; HTH-type transcriptional regulator, cell division transcriptional repressor
K20391 plcR; HTH-type transcriptional regulator, pleiotropic regulator of extracellular virulence genes
K20375 ropB, rgg1; HTH-type transcriptional regulator, pheromone-responsive regulator
K20380 traA; HTH-type transcriptional regulator, pheromone-responsive repressor
K18831 higA; HTH-type transcriptional regulator / antitoxin HigA
K20388 cylR2; HTH-type transcriptional regulator, cytolysin regulator
K20377 prgX; HTH-type transcriptional regulator, major conjugation operon repressor
K21557 susR; HTH-type transcriptional regulator, polysaccharide utilization system transcription regulator
K09720 nrpRI; HTH-type transcriptional regulator, global nitrogen regulator NrpRI
K22109 gbsR; HTH-type transcriptional regulator, glycine betaine synthesis regulator
K22301 opcR; HTH-type transcriptional regulator, osmoprotectant uptake regulator
K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
K06930 bat; HTH-type transcriptional regulator, bacterioopsin transcriptional activator and related proteins
K23348 dmsR; HTH-type transcriptional regulator, dimethyl sulfoxide reductase transcription regulator
K09714 tfx; HTH-type transcriptional regulator, fmd operon transcriptional regulator
K09685 purR; HTH-type transcriptional regulator, purine operon repressor
K26599 gfcR; HTH-type transcriptional regulator, activator of D-glucose/D-fructose catabolism
K10941 flrA, fleQ, flaK; sigma-54 dependent transcriptional regulator, flagellar regulatory protein
K18219 txr; sigma-54 dependent transcriptional regulator, tetracycline resistant transcriptional regulator
K20919 vpsR, cpsR; sigma-54 dependent transcriptional regulator, positive regulator of biofilm formation
K17473 dgaR; sigma-54 dependent transcriptional regulator, dga operon transcriptional activator
K19505 gfrR; sigma-54 dependent transcriptional regulator, gfr operon transcriptional activator
K21405 acoR; sigma-54 dependent transcriptional regulator, acetoin dehydrogenase operon transcriptional activator AcoR
K11908 vasH; sigma-54 dependent transcriptional regulator
K11917 sfa3; sigma-54 dependent transcriptional regulator
K11914 sfa2; sigma-54 dependent transcriptional regulator
K26990 rsoA; sigma-O factor regulatory protein RsoA
K12146 hyfR; hydrogenase-4 transcriptional activator
K12266 norR; anaerobic nitric oxide reductase transcription regulator
K15836 fhlA; formate hydrogenlyase transcriptional activator
K02584 nifA; Nif-specific regulatory protein
K02647 cdaR; carbohydrate diacid regulator
K06714 rocR; arginine utilization regulatory protein
K02019 modE; molybdate transport system regulatory protein
K01926 rex; redox-sensing transcriptional repressor
K03706 codY; transcriptional pleiotropic repressor
K17071 dcmR; transcriptional repressor of dcmA and dcmR
K07725 csa3; CRISPR-associated protein Csa3
K21829 dauR; D-arginine utilization repressor
K27097 espR; ESX-1-secreted protein regulator
K07726 K07726; putative transcriptional regulator
K07727 K07727; putative transcriptional regulator
K07728 K07728; putative transcriptional regulator
K07729 K07729; putative transcriptional regulator
K07730 K07730; putative transcriptional regulator
K07731 K07731; putative transcriptional regulator
|
Ribbon-helix-helix
|
Other transcription factors
|
Transcription Factors