KEGG ORTHOLOGY: K09337

ORTHOLOGY: K09337

Entry

K09337                      KO

Symbol

CRX

Name

cone-rod homeobox protein

Disease

H00481

Cone-rod dystrophy and cone dystrophy

H00837

Leber congenital amaurosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K09337  CRX; cone-rod homeobox protein
Transcription factors [BR:ko03000]
Eukaryotic type
  Helix-turn-helix
   Homeo domain Paired-related
    K09337  CRX; cone-rod homeobox protein

Genes

HSA:

1406(CRX)

PTR:	468934(CRX)

PPS:	100978571(CRX)

GGO:	101135543(CRX)

PON:	100462556(CRX) 129047394(TPRX2)

PPYG:

129020743(CRX)

NLE:	100603648(CRX)

HMH:	116479418(CRX)

SSYN:

129461211(CRX)

MCC:	717550(CRX)

MTHB:

126943496

MNI:	105478616(CRX)

CSAB:

103234952(CRX)

CATY:

105595216(CRX)

PANU:

101000263(CRX)

TGE:	112612708(CRX)

MLEU:

105531892(CRX)

RRO:	104673377(CRX)

RBB:	108540203(CRX)

PTEH:

111520119(CRX)

CANG:

105500705(CRX)

CJC:	128930449(CRX)

SBQ:	101034592 101038406(CRX)

CIMI:

108283974(CRX)

ANAN:

105713156(CRX)

CSYR:

103276358(CRX)

MMUR:

105869616(CRX)

LCAT:

123623887(CRX)

PCOQ:

105817599(CRX)

OGA:	100949179(CRX)

MMU:	12951(Crx)

MCAL:

110299053(Crx)

MPAH:

110337104(Crx)

RNO:	60446(Crx)

MCOC:

116100385(Crx)

ANU:	117700348(Crx)

ASYL:

127684102(Crx)

MUN:

110555202

CGE:	100770134(Crx) 113837325 113838844

MAUA:

101835213(Crx)

PROB:

127238612(Crx) 127239008

PLEU:

114681411(Crx)

MORG:

121450031(Crx)

MFOT:

126493314

AAMP:

119821823(Crx)

NGI:	103729181(Crx)

HGL:	101705886(Crx)

CPOC:

100721038

CCAN:

109696547(Crx)

DORD:

105998106(Crx)

DSP:	122125878(Crx)

PLOP:

125368258(Crx)

NCAR:

MMMA:

ITI:

OCU:

OPI:

TUP:	102468792(CRX)

GVR:	103608740(CRX)

CFA:	403577(CRX)

CLUD:

112643887(CRX)

VVP:	112931207(CRX)

VLG:	121476910(CRX)

NPO:

129500914

AML:	100483087(CRX)

UMR:	103657086(CRX)

UAH:	113243205(CRX)

UAR:	123776353(CRX)

ELK:

111160791

LLV:

125089779

MPUF:

101684194(CRX)

MNP:

132005519

MLK:

131818691

NVS:	122913888(CRX)

ORO:	101362436(CRX)

EJU:	114197216(CRX)

ZCA:	113936543(CRX)

MLX:	117998038(CRX)

NSU:	110572819(CRX)

LWW:	102742964(CRX)

FCA:	100379624(CRX)

PYU:	121018702(CRX)

PCOO:

112850767(CRX)

PBG:	122494903(CRX)

PVIV:

125153475(CRX)

LRUF:

124510732

LGF:

123578130

AJU:

106989737

PTG:	102958020(CRX) 107181187(ARGFX)

PPAD:

109253148

PUC:

125915686

PLEZ:

122208891(CRX)

HHV:	120243899(CRX)

BTA:	280756(CRX)

BOM:

102287501

BIU:	109572207(CRX)

BBUB:

102396006(CRX)

BBIS:

104997747(CRX)

CHX:	102180793(CRX)

OAS:	101119581(CRX)

BTAX:

128063684(CRX)

CSUM:

138096590(CRX)

ODA:

120872215

CCAD:

122421591(CRX)

MREE:

136158847(CRX)

OVR:	110150757(CRX)

MBEZ:

129546191

SSC:	100520079(CRX)

CFR:	102504387(CRX)

CBAI:

105062572(CRX)

CDK:	105098926(CRX)

VPC:	102528703(CRX)

BACU:

103005484(CRX)

BMUS:

118885662(CRX)

LVE:	103074435(CRX)

OOR:	101272440(CRX)

LALB:

132510024(CRX)

DLE:	111180465(CRX)

PCAD:

102987281(CRX)

PSIU:

116744323(CRX)

NASI:

112415608(CRX)

ECB:	102148484(CRX)

EPZ:	103567538(CRX)

EAI:

106845146

MYB:	102252535(CRX) 102254046

MYD:	102758010(CRX)

MMYO:

118657506(CRX)

MLF:	102421962(CRX)

MDT:

132216657

MYUM:

138999488

PKL:	118715987(CRX)

EFUS:

103297672

MNA:

107540040

DRO:

112312813

SHON:

118996312(CRX)

AJM:

119035968

PDIC:

114510983(CRX)

PHAS:

123823063(CRX)

PPAM:

129082786

HAI:	109378771(CRX)

RFQ:

117034845

PALE:

102890282

PGIG:

120596762(CRX)

PVP:	105304189(CRX)

RAY:	107515983(CRX)

MJV:	108389592(CRX)

TOD:	119250461(CRX)

SARA:

101552089(CRX)

SFUM:

130044277

SETR:

126027520(CRX)

LAV:	100658375(CRX)

TMU:

101343618

ETF:	101642273(CRX)

DNM:	101426724(CRX)

GAS:

123242980

AFZ:

127556231

TVP:	118835246 118840231(CRX)

PBRV:

138153912

OAA:	100091383(CRX)

TACU:

119946136(CRX)

GGA:	103875463(CRX)

PCOC:

116238692(CRX)

LMUT:

NMEL:

CATA:

AFUL:

TGU:

ATRC:

OMA:

ACOE:

138100492(CRX)

ZLE:

HLE:

AGEN:

HHAR:

CBOY:

CUCA:

RTD:

CRID:

AMJ:	102576692(CRX)

CMY:	102934869(CRX)

CCAY:

125628065

DCC:	119847528(CRX)

CPIC:

101937048(CRX)

TST:	117888747(CRX)

CABI:

116833888

MRV:	120388203(CRX)

ACS:

ASAO:

PVT:

SUND:

PBI:	103048755(CRX)

PMUR:

107295269

CTIG:

120319886(CRX)

TSR:

106555201

PGUT:

117677699

APRI:

131204530

PTEX:

113446017(CRX)

NSS:

113426028

VKO:	123025905(CRX)

PMUA:

PRAF:

ZVI:

HCG:

GJA:

STOW:

125435679(CRX)

EMC:

129343315

XLA:	373653(crx.S) 398118(crx.L)

XTR:	548775(crx)

NPR:	108786678(CRX)

RTEM:

120913386(CRX)

BBUF:

120977314(CRX)

BGAR:

122919548(CRX)

PWL:

138259646

MUO:	115480484(CRX)

GSH:	117366100(CRX)

DRE:	353179(otx5)

SRX:

107757328

SANH:

107663560 107679444

SGH:	107557656 107572216

CCAR:

109062346 109103594

CAUA:

113058850 113090289 113114666 113114667

CGIB:

127972299 128029120

PTET:

122332955(otx5)

LROH:

127176817(otx5)

OMC:	131520623(otx5)

PPRM:

120478239 120478249(otx5)

RKG:	130085486(otx5)

MAMB:

125249692(otx5)

CIDE:

127495611

CERY:

137004976(otx5)

MASI:

127421834 127430067

TROS:

130564847(otx5)

TDW:	130428923(otx5)

MANU:

129437397(otx5)

PDAB:

135771635(otx5)

IPU:	108277615(otx5)

IFU:	128621857(otx5)

PHYP:

113544623

SMEO:

124394943(otx5)

TFD:	113637907(otx5)

TVC:	132857994(otx5)

CGAR:

128532629(otx5)

NGRA:

132900172(otx5)

TRN:	134334469(otx5)

AMEX:

103033864(otx5)

CMAO:

118827030(otx5)

EEE:

113585449

CHAR:

105909735(otx5)

SPIL:

134099431(otx5)

TRU:

101066688

TFS:

130535392

TNG:	GSTEN00026783G001

LCO:

NCC:

TBEN:

PGEO:

GACU:

EMAC:

ELY:

EFO:

PLEP:

SLUC:

ECRA:

ESP:

PFLV:

GAT:

PPUG:

119214210(otx5)

AFB:

CLUM:

PSWI:

CANA:

CVE:

MSAM:

119883327(otx5)

SCHU:

122878500(otx5)

CUD:

SPUL:

LMIX:

ALAT:

ASTR:

MZE:

ONL:

OAU:

OLA:

OML:

CSAI:

133441570(otx5)

XMA:

102217777

XCO:

114161397

XHE:

116737274

PRET:

103474857(crx)

PFOR:

PLAI:

PMEI:

GAF:

PPRL:

CVG:

CTUL:

GMU:

NFU:

KMR:

ALIM:

NWH:

AOCE:

EJA:

BFRE:

MCEP:

POV:

SSEN:

SSOE:

HHIP:

HSP:

PPLT:

SMAU:

LCF:

SDU:	111216795 111232873

SLAL:

111646684 111654230 111656785 111657152

XGL:

HCQ:

SSCV:

SBIA:

PEE:

PTAO:

BPEC:

ENY:

MALB:

BSPL:

SJO:	128360444(otx5)

SSCO:

GMH:

SASA:

STRU:

OTW:	112265275 112266861

OMY:	110503696 110507573

OGO:	123992938 124005862

ONE:	115136950 115141643

OKI:	109904722 109908903

OKE:	118395217 118396943

OMM:	135545254 135551509

OCLA:

139382973 139386110

SALP:

111949622

SNH:	120018876 120029051

CCLU:

121563908 121567510

ELS:

105026879

OEP:	134029293(otx5)

SFM:

PKI:

AANG:

AROT:

CCOG:

LOC:	102686928(crx)

PSPA:

121304899

ARUT:

117398121 117416111

PSEX:

120533584

LCM:	102351276(CRX)

CMK:

RTP:

CPLA:

HOC:

LERI:

LRJ:

SPU:

AFIL:

ACER:

TPRE:

APLN:

DPX:	DAPPUDRAFT_256759

PCLA:

123750198

PTRU:

123505067

ESN:	126987205 126987220

LPOL:

106475960

NAI:	NECAME_10930

HRF:

CRG:

CANU:

CVN:

OED:

AIRR:

MCAF:

NVE:	5517365 5517366

ATEN:

116307357

MCAZ:

138049513

MFOO:

137984361

RES:	135681342 135681476 135681548

TVS:	TRAVEDRAFT_41691

» show all

Reference

PMID:10625658

Authors

Kimura A, Singh D, Wawrousek EF, Kikuchi M, Nakamura M, Shinohara T

Title

Both PCE-1/RX and OTX/CRX interactions are necessary for photoreceptor-specific gene expression.

Journal

J Biol Chem 275:1152-60 (2000)
DOI:10.1074/jbc.275.2.1152

Sequence

[hsa:1406]

Reference

PMID:9390562

Authors

Furukawa T, Morrow EM, Cepko CL

Title

Crx, a novel otx-like homeobox gene, shows photoreceptor-specific expression and regulates photoreceptor differentiation.

Journal

Cell 91:531-41 (1997)
DOI:10.1016/s0092-8674(00)80439-0

Sequence

[mmu:12951]

LinkDB

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