KEGG ORTHOLOGY: K08540

ORTHOLOGY: K08540

Entry

K08540                      KO

Symbol

NR1I2, PXR

Name

pregnane X receptor

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K08540  NR1I2, PXR; pregnane X receptor
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors
    K08540  NR1I2, PXR; pregnane X receptor
Transcription factors [BR:ko03000]
Eukaryotic type
  Zinc finger
   Cys4 thyroid hormone receptor-like
    K08540  NR1I2, PXR; pregnane X receptor
Nuclear receptors [BR:ko03310]
1. Thyroid hormone like
  1I. Vitamin D3 like receptor
   K08540  NR1I2, PXR; pregnane X receptor

Genes

HSA:	8856(NR1I2)

PTR:	745458(NR1I2)

PPS:	100971952(NR1I2)

GGO:	101124311(NR1I2)

PON:	100439068(NR1I2)

PPYG:

129033777(NR1I2)

NLE:	100606090(NR1I2)

HMH:	116466310(NR1I2)

SSYN:

129471549(NR1I2)

MCC:	574226(NR1I2)

MCF:	101866453(NR1I2)

MTHB:

126949241

MNI:	105470331(NR1I2)

CSAB:

103228220(NR1I2)

CATY:

105589735(NR1I2)

PANU:

101024860(NR1I2)

TGE:	112618744(NR1I2)

MLEU:

105544618(NR1I2)

RRO:	104657625(NR1I2)

RBB:	108541782(NR1I2)

TFN:	117083460(NR1I2)

PTEH:

111541944(NR1I2)

CANG:

105510737(NR1I2)

CJC:	100402185(NR1I2)

SBQ:	101051844(NR1I2)

CIMI:

108292530(NR1I2)

ANAN:

105725016(NR1I2)

CSYR:

103258338(NR1I2)

MMUR:

105879916(NR1I2)

LCAT:

123630507(NR1I2)

PCOQ:

105808627(NR1I2)

OGA:	100953062(NR1I2)

MMU:	18171(Nr1i2)

MCAL:

110311710(Nr1i2)

MPAH:

110329982(Nr1i2)

RNO:	84385(Nr1i2)

MCOC:

116086407(Nr1i2)

ANU:	117718070(Nr1i2)

ASYL:

127666199(Nr1i2)

MUN:	110555391(Nr1i2)

CGE:	100767943(Nr1i2)

MAUA:

101843045(Nr1i2)

PROB:

127227161(Nr1i2)

PLEU:

114701482(Nr1i2)

MORG:

121461841(Nr1i2)

MFOT:

126505875

AAMP:

119825084(Nr1i2)

NGI:	103741947(Nr1i2)

HGL:	101722589(Nr1i2)

CPOC:

100719967(Nr1i2)

CCAN:

109685335(Nr1i2)

DORD:

105987934(Nr1i2)

DSP:	122096791(Nr1i2)

DMER:

138832330(Nr1i2)

PLOP:

125351085 125351086 125351735 125351737

NCAR:

124993659

MMMA:

107136283(Nr1i2)

ITI:	101968338(Nr1i2)

OCU:	100008739(NR1I2)

OPI:	101526532(NR1I2)

OCZ:	121171340(NR1I2)

TUP:	102477993(NR1I2)

GVR:	103595391(NR1I2)

CFA:	403482(NR1I2)

VVP:	112913702(NR1I2)

NPO:	129503653(NR1I2)

AML:	100482668(NR1I2)

UMR:	103678841(NR1I2)

UAH:	113251950(NR1I2)

UAR:	123784021(NR1I2)

ELK:

111151789

LLV:

125097845

MPUF:

101679741(NR1I2)

MNP:	132012196(NR1I2)

MLK:	131825082(NR1I2)

NVS:	122910433(NR1I2)

ORO:	101370910(NR1I2)

EJU:	114214749(NR1I2)

ZCA:	113915917(NR1I2)

MLX:	118000907(NR1I2)

NSU:	110582656(NR1I2)

LWW:	102744661(NR1I2)

FCA:	101088355(NR1I2)

PYU:	121036285(NR1I2)

PCOO:

112849872(NR1I2)

PBG:	122491480(NR1I2)

PVIV:

125174489(NR1I2)

LRUF:

124527226

LGF:	123610929(NR1I2)

AJU:

106968286

PTG:	102972449(NR1I2)

PPAD:

109266232(NR1I2)

PUC:

125921784

PLEZ:

122229278(NR1I2)

HHV:	120242923(NR1I2)

BTA:	493713(NR1I2)

BOM:	102275741(NR1I2)

BIU:	109577914(NR1I2)

BBUB:

102409277(NR1I2)

BBIS:

104992482(NR1I2)

CHX:	102176075(NR1I2)

OAS:	101118075(NR1I2)

BTAX:

128052535(NR1I2) 128071397

CSUM:

138091642(NR1I2)

ODA:	120881866(NR1I2)

CCAD:

122444735(NR1I2)

MREE:

136173298(NR1I2)

OVR:	110142606(NR1I2)

MBEZ:

129550623(NR1I2)

SSC:	397228(NR1I2)

CFR:	102504445(NR1I2)

CBAI:

105081597(NR1I2)

CDK:	105090322(NR1I2)

VPC:	102544525(NR1I2)

BACU:

103015313(NR1I2)

BMUS:

118894011(NR1I2)

LVE:	103077693(NR1I2)

OOR:	101283009(NR1I2)

LALB:

132520587(NR1I2)

GMF:	115853828(NR1I2)

DDP:	132424091(NR1I2)

DLE:	111176431(NR1I2)

PSIU:

116753206(NR1I2)

PPHC:

136122226(NR1I2)

NASI:

112416017(NR1I2)

ECB:	100070909(NR1I2)

EPZ:	103547435(NR1I2)

EAI:	106829142(NR1I2)

MYB:	102248255(NR1I2)

MYD:	102752721(NR1I2)

MMYO:

118677353(NR1I2)

MLF:	102417828(NR1I2)

MDT:	132230378(NR1I2)

MYUM:

139003874(NR1I2)

PKL:	118723276(NR1I2)

EFUS:

103290719(NR1I2)

MNA:	107527337(NR1I2)

DRO:	112320610(NR1I2)

SHON:

118986593(NR1I2)

AJM:	119059199(NR1I2)

PDIC:

114490796(NR1I2)

PHAS:

123827256(NR1I2)

MMF:	118617444(NR1I2)

PPAM:

129069628(NR1I2)

HAI:	109387254(NR1I2)

RFQ:	117035837(NR1I2)

PALE:

102894709(NR1I2)

PGIG:

120586667(NR1I2)

PVP:	105288921(NR1I2)

RAY:	107517740(NR1I2)

MJV:	108388990(NR1I2)

TOD:	119258113(NR1I2)

SARA:

101538620(NR1I2)

SETR:

126025775(NR1I2)

LAV:	100659436(NR1I2)

TMU:

101349874

ETF:	101658058(NR1I2)

DNM:	101433898(NR1I2)

MDO:	100016690(NR1I2)

GAS:	123241553(NR1I2)

SHR:	100919932(NR1I2)

AFZ:

127557195

PCW:	110208030(NR1I2)

TVP:	118837137(NR1I2)

PBRV:

138147419(NR1I2)

MLAO:

141507170(NR1I2)

XLA:	379051(nr1i2.L) 399017(nr1i2.S)

XTR:	100038168(nr1i2)

NPR:

108803211

RTEM:

120928104(NR1I2)

ACAT:

141129468(NR1I2)

BBUF:

120994336(NR1I2)

BGAR:

122922698(NR1I2)

DTC:	141091422(NR1I2)

PWL:	138248787(NR1I2)

MUO:	115470653(NR1I2)

GSH:	117358946(NR1I2)

DRE:	565875(nr1i2)

SRX:	107715907 107721572

SANH:

107661291 107702743

SGH:	107551996(nr1i2) 107578608

CCAR:

109054821 122134364

CAUA:

113053286 113108967

CGIB:

127964367 128019475

PTET:

122332294(nr1i2)

LROH:

127170680(nr1i2)

GRF:	141340446(nr1i2)

OMC:	131547335(nr1i2)

PPRM:

120487287(nr1i2)

RKG:	130076049(nr1i2)

MAMB:

125269957(nr1i2)

CIDE:

127519322

CERY:

137036343(nr1i2)

MASI:

127447047 127448193

TROS:

130556036(nr1i2)

TDW:	130427795(nr1i2)

MANU:

129452475(nr1i2)

PDAB:

135782597(nr1i2)

IPU:

108266405

IFU:	128608693(nr1i2)

PHYP:

113525859(nr1i2)

SMEO:

124383163(nr1i2)

TFD:	113653130(nr1i2)

TVC:	132850411(nr1i2)

CGAR:

128524643(nr1i2)

NGRA:

132892058(nr1i2)

TRN:	134324491(nr1i2)

AMEX:

111194878(nr1i2)

CMAO:

118808226(nr1i2)

EEE:	113578527(nr1i2)

CHAR:

105904054(nr1i2)

SPIL:

134078690(nr1i2)

ASAD:

121699608(nr1i2)

TRU:	100126185(nr1i2)

TFS:	130527392(nr1i2)

TNG:	GSTEN00026021G001

LCO:	104936876(nr1i2)

NCC:	104952808(nr1i2)

TBEN:

117481111(nr1i2)

CGOB:

115026344(nr1i2)

PGEO:

117466246(nr1i2)

GACU:

117535813(nr1i2)

EMAC:

134866891(nr1i2)

ELY:	117249279(nr1i2)

EFO:	125900029(nr1i2)

SLUC:

116046935(nr1i2)

PFLV:

114564180(nr1i2)

AFB:	129104374(nr1i2)

PSWI:

130200668(nr1i2)

CVE:	137868245(nr1i2)

MSAM:

119904212(nr1i2)

SCHU:

122885557(nr1i2)

ALAT:

119025322(nr1i2)

MZE:	101487359(nr1i2)

ONL:	100534472(nr1i2)

OAU:	116316161(nr1i2)

OML:	112155092(nr1i2)

XMA:	102224653(nr1i2)

XCO:	114147694(nr1i2)

XHE:	116722564(nr1i2)

PRET:

108166995(nr1i2)

PLAI:

106959386(nr1i2)

PMEI:

106927572(nr1i2)

GAF:	122839426(nr1i2)

PPRL:

129361210(nr1i2)

CVG:	107092049(nr1i2)

CTUL:

119798515(nr1i2)

GMU:	124870914(nr1i2)

NFU:	107389864(nr1i2)

KMR:	108232355(nr1i2)

ALIM:

106531307(nr1i2)

NWH:	119418886(nr1i2)

AOCE:

111578106(nr1i2)

EJA:	138200970(nr1i2)

BFRE:

138629760(nr1i2)

MCEP:

125017150(nr1i2)

SSEN:

122760663(nr1i2)

SSOE:

131443683(nr1i2)

LCF:

127142500

SDU:	111218540(nr1i2)

SLAL:

111662082(nr1i2)

XGL:	120801944(nr1i2)

BPEC:

110166623(nr1i2)

ENY:	140359543(nr1i2)

BSPL:

114846882(nr1i2)

SJO:	128368260(nr1i2)

SSCO:

133993218(nr1i2)

TTY:	137192808(nr1i2)

SASA:

106586651

STRU:

115161152

OTW:	112241181(nr1i2)

OMY:	100136707(nr1i2)

OGO:	124044136(nr1i2)

ONE:

115115748

OKI:

109869793

OKE:	118380636(nr1i2)

OMM:	135519104(nr1i2)

OCLA:

139403850

SALP:

111979176

SNH:	120058452(nr1i2)

SFON:

129821035(nr1i2)

CCLU:

121537088(nr1i2)

ELS:	105027874(nr1i2)

OEP:	134017499(nr1i2)

SFM:	108929511(nr1i2)

PKI:

111861029

AANG:

118222904(nr1i2)

AROT:

135251848(nr1i2)

LOC:

102695553

PSPA:

121320752(nr1i2) 121327571

ARUT:

117405091

PSEX:

120522918(nr1i2)

LCM:	102353372(NR1I2)

CMK:	103180160(nr1i2)

LRJ:

133339715

AJJ:

139976955

PFLL:

139129660

DMK:	116917611 116917612 116922976

LSAX:

YBA:

MMER:

RPHI:

Reference

PMID:19297428

Authors

Li Y, Ross-Viola JS, Shay NF, Moore DD, Ricketts ML

Title

Human CYP3A4 and murine Cyp3A11 are regulated by equol and genistein via the pregnane X receptor in a species-specific manner.

Journal

J Nutr 139:898-904 (2009)
DOI:10.3945/jn.108.103572

Sequence

[mmu:18171] [hsa:8856]

LinkDB

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