KEGG ORTHOLOGY: K08539

ORTHOLOGY: K08539

Entry

K08539                      KO

Symbol

VDR, NR1I1

Name

vitamin D3 receptor

Pathway

map04928

Parathyroid hormone synthesis, secretion and action

map04961

Endocrine and other factor-regulated calcium reabsorption

map04978

Mineral absorption

map05152

Tuberculosis

map05207

Chemical carcinogenesis - receptor activation

Disease

H00342

Tuberculosis

H01143

Vitamin D-dependent rickets

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    K08539  VDR, NR1I1; vitamin D3 receptor
  09154 Digestive system
   04978 Mineral absorption
    K08539  VDR, NR1I1; vitamin D3 receptor
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    K08539  VDR, NR1I1; vitamin D3 receptor
09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    K08539  VDR, NR1I1; vitamin D3 receptor
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K08539  VDR, NR1I1; vitamin D3 receptor
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K08539  VDR, NR1I1; vitamin D3 receptor
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K08539  VDR, NR1I1; vitamin D3 receptor
  09183 Protein families: signaling and cellular processes
   03310 Nuclear receptors
    K08539  VDR, NR1I1; vitamin D3 receptor
Protein phosphatases and associated proteins [BR:ko01009]
Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K08539  VDR, NR1I1; vitamin D3 receptor
Transcription factors [BR:ko03000]
Eukaryotic type
  Zinc finger
   Cys4 thyroid hormone receptor-like
    K08539  VDR, NR1I1; vitamin D3 receptor
Nuclear receptors [BR:ko03310]
1. Thyroid hormone like
  1I. Vitamin D3 like receptor
   K08539  VDR, NR1I1; vitamin D3 receptor

Other DBs

GO:

0008434

Genes

HSA:

7421(VDR)

PTR:	451858(VDR)

PPS:	100982355(VDR)

GGO:	101126712(VDR)

PON:	100174538(VDR)

PPYG:

129009694(VDR)

NLE:	100590313(VDR)

HMH:	116461876(VDR)

SSYN:

129491167(VDR)

MCC:	706964(VDR)

MCF:	102130594(VDR)

MTHB:

126930172

MNI:	105470057(VDR)

CSAB:

103238213(VDR)

CATY:

105580437(VDR)

PANU:

101026835(VDR)

TGE:	112635044(VDR)

MLEU:

105544946(VDR)

RRO:	104654837(VDR)

RBB:	108515961(VDR)

TFN:	117090219(VDR)

PTEH:

111555283(VDR)

CANG:

105507671(VDR)

CJC:	100399941(VDR)

SBQ:	101042864(VDR)

CIMI:

108304860(VDR)

ANAN:

105721842(VDR)

CSYR:

103269602(VDR)

MMUR:

105865468(VDR)

LCAT:

123640468(VDR)

PCOQ:

105805511(VDR)

OGA:	100963533(VDR)

MMU:	22337(Vdr)

MCAL:

110310549(Vdr)

MPAH:

110334846(Vdr)

RNO:	24873(Vdr)

MCOC:

116078840(Vdr)

ANU:	117718524(Vdr)

MUN:	110546178(Vdr)

CGE:	100767048(Vdr)

MAUA:

101829584(Vdr)

PROB:

127226014(Vdr)

PLEU:

114708567(Vdr)

MORG:

121441484(Vdr)

MFOT:

126493797

AAMP:

119823888(Vdr)

NGI:	103740628(Vdr)

HGL:	101710294(Vdr)

CPOC:

100734655(Vdr)

CCAN:

109691617(Vdr)

DORD:

105987558(Vdr)

DSP:	122106360(Vdr)

PLOP:

125365528(Vdr)

NCAR:

124983883

MMMA:

107148577(Vdr)

OCU:

100008907

OPI:	101523565(VDR)

TUP:	102503250(VDR)

GVR:	103595446(VDR)

CFA:	486588(VDR)

CLUD:

112678245(VDR)

VVP:	112921079(VDR)

VLG:	121480010(VDR)

NPO:	129505676(VDR)

AML:	100470517(VDR)

UMR:	103675426(VDR)

UAH:	113257683(VDR)

UAR:	123794808(VDR)

ELK:

111157858

LLV:

125107149

MPUF:

101685653(VDR)

MNP:	132019622(VDR)

MLK:	131838834(VDR)

NVS:	122891522(VDR)

ORO:	101371063(VDR)

EJU:	114224094(VDR)

ZCA:	113923154(VDR)

MLX:	118008915(VDR)

NSU:	110593603(VDR)

LWW:	102739653(VDR)

FCA:	100316614(VDR)

PYU:	121038664(VDR)

PCOO:

112867517(VDR)

PBG:	122473330(VDR)

PVIV:

125170734(VDR)

LRUF:

124500956

PTG:	102967814(VDR)

PPAD:

109249026(VDR)

PUC:

125920196

AJU:

106969352

HHV:	120239043(VDR)

BTA:	533656(VDR)

BOM:	102283144(VDR)

BIU:	109559171(VDR)

BBUB:

102405633(VDR)

BBIS:

104986858(VDR)

CHX:	102177594(VDR)

OAS:	101107273(VDR)

BTAX:

128048516(VDR)

ODA:	120858137 120861319

CCAD:

122427208(VDR)

MBEZ:

129536654(VDR)

SSC:	396628(VDR)

CFR:	102515222(VDR)

CBAI:

105076170(VDR)

CDK:	105103804(VDR)

VPC:	102528163(VDR)

BACU:

103007377(VDR)

BMUS:

118902138(VDR)

LVE:	103079238(VDR)

OOR:	101277927(VDR)

DLE:	111174071(VDR)

PCAD:

102985024

PSIU:

116760240(VDR)

NASI:

112394038(VDR)

ECB:	100034072(VDR)

EPZ:	103546790(VDR)

EAI:	106836840(VDR)

MYB:	102256724(VDR)

MYD:	102771685(VDR)

MMYO:

118650200(VDR)

MLF:	102425669(VDR)

MDT:	132227500(VDR)

PKL:	118729445(VDR)

EFUS:

103285233(VDR)

MNA:	107528141(VDR)

DRO:	112318327(VDR)

SHON:

118997450(VDR)

AJM:	119042013(VDR)

PDIC:

114513324(VDR)

PHAS:

123813049(VDR)

MMF:	118624015(VDR)

PPAM:

129084682(VDR)

HAI:	109372509(VDR)

RFQ:	117028540(VDR)

PALE:

102890826(VDR)

PGIG:

120618232(VDR)

PVP:	105297502(VDR)

RAY:	107499895(VDR)

MJV:	108392456(VDR)

TOD:	119247595(VDR)

SARA:

101539341(VDR)

SETR:

126022338(VDR)

LAV:	100675066(VDR)

TMU:

101343980

ETF:	101663644(VDR)

DNM:	101435111(VDR)

MDO:	100027837(VDR)

GAS:	123249445(VDR)

SHR:	100921806(VDR)

AFZ:

127537837

PCW:	110201495(VDR)

TVP:	118851784(VDR)

OAA:	100089302(VDR)

GGA:	395988(VDR)

PCOC:

116234935(VDR)

MGP:	100540002(VDR)

CJO:	107306955(VDR)

TPAI:

128073570(VDR)

LMUT:

125685502(VDR)

NMEL:

110390899(VDR)

APLA:

101791260(VDR)

ACYG:

106049588(VDR)

CATA:

118261406(VDR)

AFUL:

116499960(VDR)

TGU:	100221284(VDR)

LSR:	110480531(VDR)

SCAN:

103824966

PMOA:

120501827(VDR)

OTC:

121335585

PRUF:

121356084(VDR)

GFR:	102032089(VDR)

FAB:	101818160(VDR)

OMA:	130265889(VDR)

PHI:	102108660(VDR)

PMAJ:

107198741(VDR)

CCAE:

111942129(VDR)

CBRC:

103620428(VDR)

ETL:	114072063(VDR)

ZAB:	102070501(VDR)

ZLE:	135459077(VDR)

ACHL:

103802430(VDR)

SVG:	106863614(VDR)

MMEA:

130586748(VDR)

HRT:	120764466(VDR)

SATI:

136372764(VDR)

FPG:	101920347(VDR)

FCH:	102060237(VDR)

CCRI:

104164665(VDR)

NNT:	104406365(VDR)

SHAB:

115618627(VDR)

ACUN:

113490811(VDR)

TALA:

104358542(VDR)

ACHC:

115350871(VDR)

HALD:

104316874(VDR)

HLE:	104830279(VDR)

AGEN:

126046450

GCL:

127028440

CSTI:

104561026

LDI:	104352373(VDR)

DPUB:

104299178(VDR)

EGZ:	104124296(VDR)

NNI:	104017529(VDR)

PCRI:

104030294(VDR)

PCAO:

104052891(VDR)

PADL:

103921334(VDR)

AFOR:

103895991(VDR)

FGA:	104083172(VDR)

GSTE:

104264744(VDR)

CLV:	102091345(VDR)

MUI:	104533724(VDR)

PGUU:

104472228(VDR)

PLET:

104618276(VDR)

CMAC:

104474632

CUCA:

104055636(VDR)

TEO:	104378372(VDR)

BREG:

104640591(VDR)

OHA:	104331487(VDR)

ACAR:

104529777(VDR)

CPEA:

104393003(VDR)

CVF:

104293549

RTD:	128901341(VDR)

AAM:	106485575(VDR)

AROW:

112960904(VDR)

NPD:	112952238(VDR)

TGT:	104566288(VDR)

DNE:	112994909(VDR)

SCAM:

104145516(VDR)

ASN:	102377130(VDR)

AMJ:	102577245(VDR)

CPOO:

109323460(VDR)

GGN:	109295318(VDR)

PSS:	102450544(VDR)

CMY:	102936599(VDR)

CCAY:

125627580(VDR)

DCC:	119845620(VDR)

CPIC:

101946974(VDR)

TST:	117888603(VDR)

CABI:

116828483(VDR)

MRV:	120391059(VDR)

ACS:	100559117(vdr)

ASAO:

132767656(VDR)

PVT:	110074384(VDR)

SUND:

121920839(VDR)

PBI:	103053117(VDR)

PMUR:

107291589(VDR)

CTIG:

120309969(VDR)

TSR:	106540378(VDR)

PGUT:

117662672(VDR)

APRI:

131189965(VDR)

PTEX:

113445497(VDR)

NSS:	113418437(VDR)

VKO:	123029760(VDR)

PMUA:

114593039(VDR)

PRAF:

128406783(VDR)

ZVI:	118077574(VDR)

HCG:	128347647(VDR)

GJA:	107119667(VDR)

STOW:

125430076(VDR)

EMC:	129346093(VDR)

XLA:	108708623(vdr.L) 378575(vdr.S)

XTR:	100491661(vdr)

NPR:	108793560(VDR)

RTEM:

120929389(VDR)

BBUF:

120996140(VDR)

BGAR:

122932925(VDR)

MUO:	115466718(VDR)

GSH:	117358040(VDR)

DRE:	30076(vdra) 564511(vdrb)

SRX:	107711077 107733590 107747630 107748291

SANH:

107667372 107673565 107701250 107702164

SGH:	107565314 107582718 107585146

CCAR:

109053355 109066506 109080787 109080788

CAUA:

113041353 113050348 113065759 113094038 113097595

CGIB:

127944995 127959449 128011455 128015724

PTET:

122347220(vdrb) 122347266

LROH:

127161939(vdra) 127166577(vdrb)

OMC:	131532304(vdra) 131542232(vdrb)

PPRM:

120484108(vdra) 120491365(vdrb)

RKG:	130069430(vdra) 130087567(vdrb)

MAMB:

125260698(vdra) 125273645(vdrb)

CIDE:

127505565 127514432

CERY:

137009807(vdra) 137010582(vdrb)

MASI:

127418619 127420284 127446505 127448838

TROS:

130556410(vdrb) 130571830(vdra)

TDW:	130408907(vdra) 130424494(vdrb)

MANU:

129450046(vdrb)

IPU:	108272216(vdrb) 108276459(vdra)

IFU:	128614786(vdrb) 128618930(vdra)

PHYP:

113530284(vdr) 113545847

SMEO:

124393144(vdrb) 124399335(vdra)

TFD:	113641858(vdra) 113660525(vdrb)

TVC:	132844158(vdrb) 132861853(vdra)

TRN:	134316627(vdrb) 134333078(vdra)

AMEX:

103045245(vdrb) 103045919(vdra)

CMAO:

118808239(vdrb) 118822170(vdra)

EEE:	113570306 113574573

CHAR:

105895934

TRU:	101063381 101075951

TFS:	130524362 130530416

TNG:	GSTEN00010085G001 GSTEN00013513G001 GSTEN00013514G001

LCO:	104929893 104937510

NCC:	104949576(vdr)

TBEN:

CGOB:

PGEO:

GACU:

EMAC:

ELY:	117257493 117257793

EFO:	125886951 125891320

PLEP:

121947225 121949622

SLUC:

116040711 116067703

ECRA:

117943381 117947284

ESP:	116688051 116692359

PFLV:

114554225 114559252

GAT:	120829448 120834978

PPUG:

119222279 119229608

AFB:	129099796 129105753

CLUM:

PSWI:

MSAM:

SCHU:

CUD:	121505094 121517260

ALAT:

119021195 119022671

ASTR:

137595121 137606050

MZE:	101467549 101474679

ONL:	100695813 100696631

OAU:	116311198 116326505

OLA:	100169844(vdralpha) 100169845(vdr)

OML:	112144739 112159254

CSAI:

133448827(vdrb) 133456580

XMA:	102227505 102231441

XCO:	114135384 114161274

XHE:	116710492 116723584

PRET:

103464934 103466861

PFOR:

103139516 103156109

PLAI:

106952768(vdr)

PMEI:

106933383(vdr)

GAF:	122827699 122833768

PPRL:

129352713 129371599

CVG:	107096638 107103431

CTUL:

119775623 119791757

GMU:	124856444 124867356

NFU:	107385536 107391321

KMR:	108233105 108239853

ALIM:

106518359 106522380 106535289

NWH:	119411698 119417733

AOCE:

111565886 111577005

MCEP:

125006675 125007701

CSEM:

103384745 103386109

POV:	109629378 109630952

SSEN:

122768106 122777751

HHIP:

117761317 117765304

HSP:	118104480 118110734

PPLT:

128441913 128446960

SMAU:

118308731 118316740

LCF:	108882657 108884043

SDU:	111221695 111230693

SLAL:

111655257 111667759

XGL:	120783237 120804384

HCQ:	109511784 109522239

SSCV:

125977681 125988751

SBIA:

133490830 133507482

PEE:	133400166 133408307

PTAO:

133475409 133483344

BPEC:

110157973 110165704

MALB:

109956265 109967218(vdr)

BSPL:

114855551 114858442

SJO:	128355028 128357858

SASA:

100136371 100136412(vdr0) 106565233 106566896

STRU:

115150157 115165835 115168165 115208313

OTW:	112221988 112244981 112246240 112267746

OMY:	100136219 110493951 110528497 110532402

OGO:	124002473 124027074 124032076 124045846

ONE:	115102287 115131812 115132270 115142795

OKI:	109867661 109869863 109908093 116374233

OKE:	118360920 118372250 118388984 118400575

SALP:

111966563 111970458 111976267 112074754

SNH:	120059182 120061205 120064230(vdrb) 120065408

CCLU:

121538455 121545591 121575539 121578020

ELS:	105022772 105024800

SFM:	108918597 108939286

PKI:	111840340 111851692

AANG:

118208312

LOC:	102691130(vdr)

PSPA:

121308891

ARUT:

117401064 117962563

PSEX:

120524950

LCM:	102360440(VDR)

CMK:

CPLA:

HOC:

LERI:

PMRN:

103091731 116941047 116948345

LRJ:	133344769 133345191 133349771

BBEL:

109463407

CIN:	751590(vdr-b) 778791(vdr-a)

SCLV:

120330841 120331580 120343952

CSET:

123314414

OTU:

111415169

DMK:

116926214

PJA:	122251684 122259324

PCHN:

125029083

HAME:

121867802 121878292 121878351

PCLA:

PTRU:

TCF:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

DFR:

CSCU:

PTEP:

UDV:

SDM:	118189166 118201160

LPOL:

106460522 106464311 106465460 106473867 106475368

PMEO:

129587073

HRO:	HELRODRAFT_87546

PVUL:

126815995 126816386 126816390

PCAN:

112564238 112564427

BGT:	106057761 106060579 106060663 106077941

GAE:	121383643 121384802

HRF:	124112455 124119305 124132903 124139390

HRJ:	124252825 124274386 124280647

CRG:	105328926 105333761 105336419

CANU:

128180405 128181137 128181910

CVN:	111133851 111134737 111135284

OED:	125657607 125659151 125659748

MYI:	110446740 110451062 110456932

PMAX:

117338828 117339336 117339612

MMER:

123535063 123536228 123546814 123547514 123547835

RPHI:

132716260 132739265 132743410 132749421

DPOL:

127841980 127851510 127858826

MAEA:

128211190 128211630 128212107 128230371 128237256 128240137 128240186 128240698

OBI:	106868710 106877119

OSN:	115223314 115224978 115232418 115232533

LJP:	135466769 135469329

LAK:

106160755

LLON:

135489608 135489775 135491713 135502290

» show all

Reference

PMID:2835767

Authors

Baker AR, McDonnell DP, Hughes M, Crisp TM, Mangelsdorf DJ, Haussler MR, Pike JW, Shine J, O'Malley BW

Title

Cloning and expression of full-length cDNA encoding human vitamin D receptor.

Journal

Proc Natl Acad Sci U S A 85:3294-8 (1988)
DOI:10.1073/pnas.85.10.3294

Sequence

[hsa:7421]

Reference

PMID:16406653

Authors

Ebert R, Schutze N, Adamski J, Jakob F

Title

Vitamin D signaling is modulated on multiple levels in health and disease.

Journal

Mol Cell Endocrinol 248:149-59 (2006)
DOI:10.1016/j.mce.2005.11.039

LinkDB

DBGET integrated database retrieval system