KEGG    Network variation - Autophagy
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ENTRYnt06532
NameAutophagy
CategoryPathway view; Cellular process
Pathwayhsa04140 Autophagy - animal
Display drug-target relation   disease type
N00155      mTORC1ULK1_complexPI3KC3-C1
N00177    KSHV     vBCL2(BECN1+PIK3C3+ATG1..
N01717        ATXN3BECN1
    SCA3     ATXN3*
N01715        PIPI3KC3-C1PI3P(WIPI,ZFYVE1)
    NBIA5           WDR45*
    NEDSBAS           WDR45B*
N01142    RAB1A(C9orf72+WDR41+SMC..ULK1_complex
    FTDALS1   C9orf72*
 
N00156    LC3ATG4ATG7ATG3(ATG12+ATG5+ATG16L..LC3-II
    SCAR31     ATG7*
    SCAR25         ATG5*
    IBD10         ATG16L1*
N00176    KSHV     vFLIPATG3
N01284    Shigella     IcsPC3=ATG16L
N01716          Ubiquitinated_prot..=(SQSTM1,NBR1,OPTN,..=LC3-II
    PDB3/DMRV/FTDALS3         SQSTM1*
    ALS12         OPTN*
    GLC1E         OPTN*
 
N01718    RUBCNLRUBCNPI3KC3-C2
    SCAR15   RUBCN*
 
N01719    (EPM2A+NHLRC1)(BECN1,PIK3C3,PIK3..
    EPM2A EPM2A*
    EPM2B NHLRC1*
 
N01720    (VAMP8,STX7)=SNAP29=(STX17,YKT6)
    CEDNIK   SNAP29*
N01721    RAB7=(EPG5,PLEKHM1,BIRC..=LC3-II
    CMT2B RAB7A*
    HLD12/DYT32   VPS11*
    HSAN9   TECPR2*
N01722    LAMP2=GORASP2=LC3-II
    DD LAMP2*

Disease nameDisease category
KSHVH00041Kaposi sarcomaCancer
SCA3H00063Spinocerebellar ataxia (SCA)Neurodegenerative disease
NBIA5H00833Neurodegeneration with brain iron accumulationNervous system disease
NEDSBASH02470Neurodevelopmental disorder with structural brain abnormalitiesCongenital malformation
FTDALS1H02342Frontotemporal dementia and amyotrophic lateral sclerosisNervous system disease
SCAR31H01891Autosomal recessive spinocerebellar ataxiasNeurodegenerative disease
SCAR25H01891Autosomal recessive spinocerebellar ataxiasNeurodegenerative disease
IBD10H01227Inflammatory bowel disease (IBD)Immune system disease
ShigellaH00299ShigellosisBacterial infectious disease
PDB3/DMRV/FTDALS3H00437Paget disease of boneMusculoskeletal disease
H00594Distal myopathyNervous system disease
H02342Frontotemporal dementia and amyotrophic lateral sclerosisNervous system disease
ALS12H00058Amyotrophic lateral sclerosis (ALS)Neurodegenerative disease
GLC1EH00612Primary open angle glaucomaNervous system disease
SCAR15H01891Autosomal recessive spinocerebellar ataxiasNeurodegenerative disease
EPM2AH00810Progressive myoclonic epilepsyNervous system disease
EPM2BH00810Progressive myoclonic epilepsyNervous system disease
CEDNIKH00799CEDNIK syndromeCongenital malformation
CMT2BH00264Charcot-Marie-Tooth diseaseNeurodegenerative disease
HLD12/DYT32H00679Hypomyelinating leukodystrophyInherited metabolic disorder
H00831Primary dystoniaNervous system disease
HSAN9H00265Hereditary sensory and autonomic neuropathyNervous system disease
DDH00150Danon diseaseInherited metabolic disorder, Lysosomal disease