PATHWAY: cdk05022 Help
Entry
Name
Pathways of neurodegeneration - multiple diseases - Camelus dromedarius (Arabian camel)
Description
Neurodegeneration is generally defined as progressive, irreversible loss of neurons, which may affect either the peripheral or central nervous system (CNS). Neurodegenerative diseases (NDs) include highly debilitating illnesses, such as Alzheimer (AD), Parkinson disease (PD), amyotrophic lateral sclerosis, Huntington disease, spinocerebellar ataxias, and prion diseases (PrD). The hallmark event, which is thought to be at the root of these diseases, is the progressive accumulation of misfolded protein aggregates. Major basic processes include abnormal protein dynamics due to deficiency of the ubiquitin-proteosome-autophagy system, oxidative stress and free radical formation, endoplasmic reticulum stress, mitochondrial dysfunction and (secondary) disruptions of axonal transport.
Class
Human Diseases; Neurodegenerative disease
BRITE hierarchy
Pathway map
cdk05022 Pathways of neurodegeneration - multiple diseases
Ortholog table
Organism
Camelus dromedarius (Arabian camel) [GN:
cdk ]
Gene
105104446 SPTBN2; spectrin beta chain, non-erythrocytic 2 isoform X3 [KO:K23932 ]
105098361 GRM5; LOW QUALITY PROTEIN: metabotropic glutamate receptor 5 [KO:K04604 ]
105087414 guanine nucleotide-binding protein G(q) subunit alpha isoform X1 [KO:K04634 ]
105101292 PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858 ] [EC:3.1.4.11 ]
105101500 PLCB4; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [KO:K05858 ] [EC:3.1.4.11 ]
105101545 PLCB3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform X4 [KO:K05858 ] [EC:3.1.4.11 ]
105096910 PLCB2; LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 [KO:K05858 ] [EC:3.1.4.11 ]
105085024 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [KO:K01116 ] [EC:3.1.4.11 ]
105093661 TRPC3; short transient receptor potential channel 3 isoform X1 [KO:K04966 ]
105085597 SIGMAR1; sigma non-opioid intracellular receptor 1 isoform X1 [KO:K20719 ]
105093156 ITPR1; inositol 1,4,5-trisphosphate receptor type 1 isoform X2 [KO:K04958 ]
105101373 ITPR3; inositol 1,4,5-trisphosphate receptor type 3 isoform X1 [KO:K04960 ]
105106183 GRIN1; glutamate receptor ionotropic, NMDA 1 isoform X1 [KO:K05208 ]
105104658 GRIN2C; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2C [KO:K05211 ]
105098957 GRIN2D; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2D [KO:K05212 ]
105102103 CACNA1B; LOW QUALITY PROTEIN: voltage-dependent N-type calcium channel subunit alpha-1B [KO:K04849 ]
105100748 CACNA1C; voltage-dependent L-type calcium channel subunit alpha-1C isoform X1 [KO:K04850 ]
105093176 CACNA1D; voltage-dependent L-type calcium channel subunit alpha-1D isoform X1 [KO:K04851 ]
105103284 CACNA1F; voltage-dependent L-type calcium channel subunit alpha-1F isoform X1 [KO:K04853 ]
105090835 CACNA1S; voltage-dependent L-type calcium channel subunit alpha-1S isoform X1 [KO:K04857 ]
105104257 CHRNA7; neuronal acetylcholine receptor subunit alpha-7 [KO:K04809 ]
105091425 PSMC6; 26S proteasome regulatory subunit 10B isoform X1 [KO:K03064 ]
105106880 PSMC3; 26S proteasome regulatory subunit 6A isoform X1 [KO:K03065 ]
105090405 PSMC5; 26S proteasome regulatory subunit 8 isoform X1 [KO:K03066 ]
105085877 PSMD2; 26S proteasome non-ATPase regulatory subunit 2 [KO:K03028 ]
105093755 PSMD1; 26S proteasome non-ATPase regulatory subunit 1 isoform X1 [KO:K03032 ]
105099032 PSMD3; 26S proteasome non-ATPase regulatory subunit 3 [KO:K03033 ]
105102519 PSMD9; 26S proteasome non-ATPase regulatory subunit 9 isoform X2 [KO:K06693 ]
105092316 PSMD12; 26S proteasome non-ATPase regulatory subunit 12 [KO:K03035 ]
105088223 PSMD11; 26S proteasome non-ATPase regulatory subunit 11 [KO:K03036 ]
105094369 PSMD6; 26S proteasome non-ATPase regulatory subunit 6 [KO:K03037 ]
105088390 PSMD7; 26S proteasome non-ATPase regulatory subunit 7 [KO:K03038 ]
105105733 PSMD13; 26S proteasome non-ATPase regulatory subunit 13 isoform X2 [KO:K03039 ]
105103211 PSMD4; 26S proteasome non-ATPase regulatory subunit 4 isoform X1 [KO:K03029 ]
105093692 PSMD14; 26S proteasome non-ATPase regulatory subunit 14 isoform X2 [KO:K03030 ]
105096924 PSMD8; 26S proteasome non-ATPase regulatory subunit 8 [KO:K03031 ]
105095674 ADRM1; proteasomal ubiquitin receptor ADRM1 isoform X1 [KO:K06691 ]
105098863 VAPB; vesicle-associated membrane protein-associated protein B/C isoform X1 [KO:K10707 ]
105092786 ATF6; cyclic AMP-dependent transcription factor ATF-6 alpha [KO:K09054 ]
105092320 ERN1; serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1 [KO:K08852 ] [EC:2.7.11.1 3.1.26.-]
105086172 EIF2S1; eukaryotic translation initiation factor 2 subunit 1 [KO:K03237 ]
105091928 ATF4; cyclic AMP-dependent transcription factor ATF-4 [KO:K04374 ]
105102174 SLC6A3; LOW QUALITY PROTEIN: sodium-dependent dopamine transporter [KO:K05036 ]
105088855 PINK1; LOW QUALITY PROTEIN: serine/threonine-protein kinase PINK1, mitochondrial [KO:K05688 ] [EC:2.7.11.1 ]
105105846 NDUFV3; NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial isoform X1 [KO:K03944 ]
116150922 NDUFA1; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 [KO:K03945 ]
105098104 NDUFA2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 [KO:K03946 ]
105105514 NDUFA3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 [KO:K03947 ]
105098308 NDUFA4L2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 [KO:K03948 ]
105085342 NDUFA5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 [KO:K03949 ]
105091880 NDUFA6; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 [KO:K03950 ]
105087580 NDUFA7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 [KO:K03951 ]
105104365 NDUFA8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 isoform X2 [KO:K03952 ]
105091332 NDUFA9; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial [KO:K03953 ]
105105383 NDUFA10; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial [KO:K03954 ]
105091762 NDUFA11; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 [KO:K03956 ]
105097420 NDUFA12; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 [KO:K11352 ]
105103723 NDUFA13; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 [KO:K11353 ]
105096144 NDUFB1; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 [KO:K03957 ]
105096996 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 [KO:K03957 ]
105091662 NDUFB2; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial [KO:K03958 ]
105099177 NDUFB3; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 [KO:K03959 ]
105090315 NDUFB4; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 [KO:K03960 ]
105085920 NDUFB5; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial [KO:K03961 ]
105085566 NDUFB6; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 [KO:K03962 ]
105105974 NDUFB7; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 [KO:K03963 ]
105084324 NDUFB8; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial [KO:K03964 ]
105096438 NDUFB9; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 [KO:K03965 ]
105099726 NDUFB10; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 [KO:K03966 ]
105101950 NDUFB11; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial [KO:K11351 ]
105100106 NDUFS2; NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial [KO:K03935 ] [EC:7.1.1.2 ]
105106884 NDUFS3; NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial [KO:K03936 ] [EC:7.1.1.2 ]
105087155 NDUFS4; NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial isoform X1 [KO:K03937 ]
105090973 NDUFS5; NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 [KO:K03938 ]
105102170 NDUFS6; NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial [KO:K03939 ]
105104129 NDUFS7; NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial isoform X1 [KO:K03940 ] [EC:7.1.1.2 ]
105104408 NDUFS8; NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial isoform X1 [KO:K03941 ] [EC:7.1.1.2 ]
116147839 LOW QUALITY PROTEIN: NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial-like [KO:K03941 ] [EC:7.1.1.2 ]
116147841 LOW QUALITY PROTEIN: NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial-like [KO:K03941 ] [EC:7.1.1.2 ]
105087084 NDUFC1; NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial [KO:K03967 ]
105102189 SDHA; succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial isoform X1 [KO:K00234 ] [EC:1.3.5.1 ]
105107079 SDHB; succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial [KO:K00235 ] [EC:1.3.5.1 ]
105100098 SDHC; succinate dehydrogenase cytochrome b560 subunit, mitochondrial isoform X1 [KO:K00236 ]
105094129 SDHD; succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial [KO:K00237 ]
105092293 cytochrome b-c1 complex subunit 2, mitochondrial isoform X1 [KO:K00415 ]
105092921 cytochrome b-c1 complex subunit 6, mitochondrial isoform X1 [KO:K00416 ]
105098909 cytochrome c oxidase subunit 4 isoform 1, mitochondrial [KO:K02263 ]
105100820 cytochrome c oxidase subunit 4 isoform 2, mitochondrial isoform X1 [KO:K02263 ]
105092495 cytochrome c oxidase subunit 4 isoform 1, mitochondrial-like [KO:K02263 ]
105103545 cytochrome c oxidase subunit 7A-related protein, mitochondrial [KO:K02270 ]
105091350 ATP5F1C; ATP synthase subunit gamma, mitochondrial isoform X1 [KO:K02136 ]
105102044 ATP5PB; ATP synthase F(0) complex subunit B1, mitochondrial [KO:K02127 ]
105094601 ATP5MC2; ATP synthase F(0) complex subunit C2, mitochondrial [KO:K02128 ]
105095776 ATP5MC1; ATP synthase F(0) complex subunit C1, mitochondrial [KO:K02128 ]
105097572 ATP5MC3; ATP synthase F(0) complex subunit C3, mitochondrial [KO:K02128 ]
105086808 ATP5PF; ATP synthase-coupling factor 6, mitochondrial isoform X1 [KO:K02131 ]
105090242 VDAC1; voltage-dependent anion-selective channel protein 1 [KO:K05862 ]
105100100 TOMM40L; mitochondrial import receptor subunit TOM40B [KO:K11518 ]
105095467 TOMM40; mitochondrial import receptor subunit TOM40 homolog [KO:K11518 ]
105092475 MCU; calcium uniporter protein, mitochondrial isoform X1 [KO:K20858 ]
105105602 CALML6; LOW QUALITY PROTEIN: calmodulin-like protein 6 [KO:K02183 ]
105102643 PPP3CC; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1 [KO:K04348 ] [EC:3.1.3.16 ]
105092463 PPP3CB; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1 [KO:K04348 ] [EC:3.1.3.16 ]
105089593 PPP3CA; serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1 [KO:K04348 ] [EC:3.1.3.16 ]
105101547 BAD; bcl2-associated agonist of cell death isoform X1 [KO:K02158 ]
105092770 FASLG; tumor necrosis factor ligand superfamily member 6 [KO:K04389 ]
105102832 FAS; tumor necrosis factor receptor superfamily member 6 isoform X1 [KO:K04390 ]
105104389 FADD; LOW QUALITY PROTEIN: FAS-associated death domain protein [KO:K02373 ]
105100737 BID; LOW QUALITY PROTEIN: BH3-interacting domain death agonist [KO:K04726 ]
105092440 VDAC2; voltage-dependent anion-selective channel protein 2 [KO:K15040 ]
105086434 VDAC3; voltage-dependent anion-selective channel protein 3 isoform X1 [KO:K15041 ]
105098528 LOW QUALITY PROTEIN: cytochrome c, testis-specific-like [KO:K08738 ]
105097442 APAF1; apoptotic protease-activating factor 1 isoform X1 [KO:K02084 ]
105084948 MAP1LC3A; microtubule-associated proteins 1A/1B light chain 3A [KO:K10435 ]
105104671 MAP1LC3B; microtubule-associated proteins 1A/1B light chain 3B [KO:K10435 ]
105093693 TANK; TRAF family member-associated NF-kappa-B activator isoform X1 [KO:K12650 ]
105097068 RB1CC1; LOW QUALITY PROTEIN: RB1-inducible coiled-coil protein 1 [KO:K17589 ]
105106861 AMBRA1; activating molecule in BECN1-regulated autophagy protein 1 isoform X1 [KO:K17985 ]
105091474 ATG14; beclin 1-associated autophagy-related key regulator isoform X1 [KO:K17889 ]
105102629 ATG2A; autophagy-related protein 2 homolog A isoform X1 [KO:K17906 ]
105085704 WIPI1; WD repeat domain phosphoinositide-interacting protein 1 isoform X1 [KO:K17908 ]
105104243 WIPI2; WD repeat domain phosphoinositide-interacting protein 2 isoform X1 [KO:K17908 ]
105086134 ZFYVE1; zinc finger FYVE domain-containing protein 1 isoform X1 [KO:K17603 ]
105098228 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A isoform X1 [KO:K03158 ]
105107099 TNFRSF1B; tumor necrosis factor receptor superfamily member 1B isoform X1 [KO:K05141 ]
105106448 BDNF; LOW QUALITY PROTEIN: brain-derived neurotrophic factor [KO:K04355 ]
105095914 DNAH9; LOW QUALITY PROTEIN: dynein heavy chain 9, axonemal [KO:K10408 ]
105105809 DNAH17; LOW QUALITY PROTEIN: dynein heavy chain 17, axonemal [KO:K10408 ]
105086932 DNALI1; axonemal dynein light intermediate polypeptide 1 [KO:K10410 ]
105104948 DNAI2; dynein intermediate chain 2, axonemal isoform X1 [KO:K11143 ]
105089916 CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X8 [KO:K04515 ] [EC:2.7.11.17 ]
105098484 CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1 [KO:K04515 ] [EC:2.7.11.17 ]
105092345 CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1 [KO:K04515 ] [EC:2.7.11.17 ]
105094238 LRP6; low-density lipoprotein receptor-related protein 6 isoform X1 [KO:K03068 ]
105104473 LRP5; low-density lipoprotein receptor-related protein 5 isoform X1 [KO:K03068 ]
105085889 DVL3; LOW QUALITY PROTEIN: segment polarity protein dishevelled homolog DVL-3 [KO:K02353 ]
105105575 DVL1; segment polarity protein dishevelled homolog DVL-1 isoform X1 [KO:K02353 ]
105103047 segment polarity protein dishevelled homolog DVL-2 isoform X1 [KO:K02353 ]
105104128 APC2; LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2 [KO:K02085 ]
105090848 AGER; advanced glycosylation end product-specific receptor [KO:K19722 ]
105089560 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580 ]
105085658 CSF1; macrophage colony-stimulating factor 1 isoform X2 [KO:K05453 ]
Compound
C01245 D-myo-Inositol 1,4,5-trisphosphate
C04549 1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04599 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
C11310 1-Methyl-4-phenylpyridinium
C16514 Amyloid beta protein 40
C16515 Amyloid beta protein 42
C21011 [Protein]-N(epsilon)-(carboxymethyl)lysine
C21012 [Protein]-N(epsilon)-(carboxyethyl)lysine
Reference
Authors
Gan L, Cookson MR, Petrucelli L, La Spada AR
Title
Converging pathways in neurodegeneration, from genetics to mechanisms.
Journal
Reference
Authors
Dugger BN, Dickson DW
Title
Pathology of Neurodegenerative Diseases.
Journal
Reference
Authors
Jellinger KA
Title
Basic mechanisms of neurodegeneration: a critical update.
Journal
Reference
Authors
Jellinger KA
Title
Recent advances in our understanding of neurodegeneration.
Journal
Reference
Authors
Van Bulck M, Sierra-Magro A, Alarcon-Gil J, Perez-Castillo A, Morales-Garcia JA
Title
Novel Approaches for the Treatment of Alzheimer's and Parkinson's Disease.
Journal
Reference
Authors
Ross CA, Poirier MA
Title
Protein aggregation and neurodegenerative disease.
Journal
Reference
Authors
Soto C, Pritzkow S
Title
Protein misfolding, aggregation, and conformational strains in neurodegenerative diseases.
Journal
Reference
Authors
Dantuma NP, Bott LC
Title
The ubiquitin-proteasome system in neurodegenerative diseases: precipitating factor, yet part of the solution.
Journal
Reference
Authors
Zheng C, Geetha T, Babu JR
Title
Failure of ubiquitin proteasome system: risk for neurodegenerative diseases.
Journal
Reference
Authors
Park H, Kang JH, Lee S
Title
Autophagy in Neurodegenerative Diseases: A Hunter for Aggregates.
Journal
Reference
Authors
Malik BR, Maddison DC, Smith GA, Peters OM
Title
Autophagic and endo-lysosomal dysfunction in neurodegenerative disease.
Journal
Reference
Authors
Metaxakis A, Ploumi C, Tavernarakis N
Title
Autophagy in Age-Associated Neurodegeneration.
Journal
Reference
Authors
Vidal RL, Matus S, Bargsted L, Hetz C
Title
Targeting autophagy in neurodegenerative diseases.
Journal
Reference
Authors
Menzies FM, Fleming A, Caricasole A, Bento CF, Andrews SP, Ashkenazi A, Fullgrabe J, Jackson A, Jimenez Sanchez M, Karabiyik C, Licitra F, Lopez Ramirez A, Pavel M, Puri C, Renna M, Ricketts T, Schlotawa L, Vicinanza M, Won H, Zhu Y, Skidmore J, Rubinsztein DC
Title
Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities.
Journal
Reference
Authors
Chu CT
Title
Mechanisms of selective autophagy and mitophagy: Implications for neurodegenerative diseases.
Journal
Reference
Authors
Kim I, Xu W, Reed JC
Title
Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities.
Journal
Reference
Authors
Doyle KM, Kennedy D, Gorman AM, Gupta S, Healy SJ, Samali A
Title
Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders.
Journal
Reference
Authors
Halliday M, Hughes D, Mallucci GR
Title
Fine-tuning PERK signaling for neuroprotection.
Journal
Reference
Authors
Rozpedek-Kaminska W, Siwecka N, Wawrzynkiewicz A, Wojtczak R, Pytel D, Diehl JA, Majsterek I
Title
The PERK-Dependent Molecular Mechanisms as a Novel Therapeutic Target for Neurodegenerative Diseases.
Journal
Reference
Authors
Hetz C, Mollereau B
Title
Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases.
Journal
Reference
Authors
Bezprozvanny I
Title
Calcium signaling and neurodegenerative diseases.
Journal
Reference
Authors
Ureshino RP, Erustes AG, Bassani TB, Wachilewski P, Guarache GC, Nascimento AC, Costa AJ, Smaili SS, Pereira GJDS
Title
The Interplay between Ca(2+) Signaling Pathways and Neurodegeneration.
Journal
Reference
Authors
Golpich M, Amini E, Mohamed Z, Azman Ali R, Mohamed Ibrahim N, Ahmadiani A
Title
Mitochondrial Dysfunction and Biogenesis in Neurodegenerative diseases: Pathogenesis and Treatment.
Journal
Reference
Authors
Morfini GA, Burns M, Binder LI, Kanaan NM, LaPointe N, Bosco DA, Brown RH Jr, Brown H, Tiwari A, Hayward L, Edgar J, Nave KA, Garberrn J, Atagi Y, Song Y, Pigino G, Brady ST
Title
Axonal transport defects in neurodegenerative diseases.
Journal
Reference
Authors
Gibbs KL, Greensmith L, Schiavo G
Title
Regulation of Axonal Transport by Protein Kinases.
Journal
Reference
Authors
Millecamps S, Julien JP
Title
Axonal transport deficits and neurodegenerative diseases.
Journal
Reference
Authors
Sleigh JN, Rossor AM, Fellows AD, Tosolini AP, Schiavo G
Title
Axonal transport and neurological disease.
Journal
Reference
Authors
Perlson E, Maday S, Fu MM, Moughamian AJ, Holzbaur EL
Title
Retrograde axonal transport: pathways to cell death?
Journal
Related pathway
cdk04141 Protein processing in endoplasmic reticulum
cdk04933 AGE-RAGE signaling pathway in diabetic complications
KO pathway
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