Entry
Name
Pathways of neurodegeneration - multiple diseases - Equus asinus (ass)
Description
Neurodegeneration is generally defined as progressive, irreversible loss of neurons, which may affect either the peripheral or central nervous system (CNS). Neurodegenerative diseases (NDs) include highly debilitating illnesses, such as Alzheimer (AD), Parkinson disease (PD), amyotrophic lateral sclerosis, Huntington disease, spinocerebellar ataxias, and prion diseases (PrD). The hallmark event, which is thought to be at the root of these diseases, is the progressive accumulation of misfolded protein aggregates. Major basic processes include abnormal protein dynamics due to deficiency of the ubiquitin-proteosome-autophagy system, oxidative stress and free radical formation, endoplasmic reticulum stress, mitochondrial dysfunction and (secondary) disruptions of axonal transport.
Class
Human Diseases; Neurodegenerative disease
BRITE hierarchy
Pathway map
eai05022 Pathways of neurodegeneration - multiple diseases
Ortholog table
Organism
Equus asinus (ass) [GN:
eai ]
Gene
106827064 CHRM3; muscarinic acetylcholine receptor M3 isoform X1 [KO:K04131 ]
106833515 SPTBN2; LOW QUALITY PROTEIN: spectrin beta chain, non-erythrocytic 2 [KO:K23932 ]
106825688 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha [KO:K04634 ]
106823191 PLCB1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [KO:K05858 ] [EC:3.1.4.11 ]
106835172 PLCB2; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1 [KO:K05858 ] [EC:3.1.4.11 ]
106833627 PLCB3; LOW QUALITY PROTEIN: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 [KO:K05858 ] [EC:3.1.4.11 ]
106834358 PLCG1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [KO:K01116 ] [EC:3.1.4.11 ]
106834075 TRPC3; short transient receptor potential channel 3 isoform X1 [KO:K04966 ]
106848450 ITPR1; inositol 1,4,5-trisphosphate receptor type 1 isoform X1 [KO:K04958 ]
106834634 ITPR3; inositol 1,4,5-trisphosphate receptor type 3 isoform X1 [KO:K04960 ]
106826757 GRIN2B; glutamate receptor ionotropic, NMDA 2B isoform X1 [KO:K05210 ]
106830197 GRIN2C; glutamate receptor ionotropic, NMDA 2C isoform X1 [KO:K05211 ]
106838305 GRIN2D; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2D [KO:K05212 ]
106822757 CACNA1B; voltage-dependent N-type calcium channel subunit alpha-1B isoform X1 [KO:K04849 ]
106839455 CACNA1C; voltage-dependent L-type calcium channel subunit alpha-1C isoform X1 [KO:K04850 ]
106822066 CACNA1D; voltage-dependent L-type calcium channel subunit alpha-1D isoform X8 [KO:K04851 ]
106826963 CACNA1F; voltage-dependent L-type calcium channel subunit alpha-1F isoform X1 [KO:K04853 ]
106823553 CACNA1S; voltage-dependent L-type calcium channel subunit alpha-1S isoform X3 [KO:K04857 ]
106834056 neuronal acetylcholine receptor subunit alpha-7 isoform X1 [KO:K04809 ]
106826770 PSMC6; 26S proteasome regulatory subunit 10B isoform X1 [KO:K03064 ]
106835533 PSMC5; 26S proteasome regulatory subunit 8 isoform X2 [KO:K03066 ]
106834518 PSMD2; 26S proteasome non-ATPase regulatory subunit 2 [KO:K03028 ]
106827890 PSMD1; 26S proteasome non-ATPase regulatory subunit 1 isoform X1 [KO:K03032 ]
106826388 PSMD3; 26S proteasome non-ATPase regulatory subunit 3 [KO:K03033 ]
106842301 PSMD9; 26S proteasome non-ATPase regulatory subunit 9 [KO:K06693 ]
106835560 PSMD12; 26S proteasome non-ATPase regulatory subunit 12 [KO:K03035 ]
106844623 PSMD11; 26S proteasome non-ATPase regulatory subunit 11 [KO:K03036 ]
106842647 PSMD6; 26S proteasome non-ATPase regulatory subunit 6 isoform X1 [KO:K03037 ]
106842138 PSMD7; 26S proteasome non-ATPase regulatory subunit 7 [KO:K03038 ]
106843856 PSMD13; 26S proteasome non-ATPase regulatory subunit 13 [KO:K03039 ]
106846512 PSMD4; 26S proteasome non-ATPase regulatory subunit 4 isoform X1 [KO:K03029 ]
106843144 PSMD14; 26S proteasome non-ATPase regulatory subunit 14 isoform X2 [KO:K03030 ]
106836062 PSMD8; 26S proteasome non-ATPase regulatory subunit 8 [KO:K03031 ]
106838407 LOW QUALITY PROTEIN: 26S proteasome complex subunit SEM1 [KO:K10881 ]
106824834 VAPB; vesicle-associated membrane protein-associated protein B/C isoform X1 [KO:K10707 ]
106831122 ATF6; cyclic AMP-dependent transcription factor ATF-6 alpha isoform X1 [KO:K09054 ]
106835569 ERN1; LOW QUALITY PROTEIN: serine/threonine-protein kinase/endoribonuclease IRE1 [KO:K08852 ] [EC:2.7.11.1 3.1.26.-]
106827800 EIF2S1; eukaryotic translation initiation factor 2 subunit 1 [KO:K03237 ]
106842437 ATF4; cyclic AMP-dependent transcription factor ATF-4 [KO:K04374 ]
106829925 NDUFV3; NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial isoform X1 [KO:K03944 ]
106845129 NDUFA1; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 [KO:K03945 ]
106823773 NDUFA2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 [KO:K03946 ]
106840869 NDUFA3; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 isoform X2 [KO:K03947 ]
106848374 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3-like [KO:K03947 ]
106832994 NDUFA4L2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 [KO:K03948 ]
106829867 NDUFA5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 [KO:K03949 ]
106848494 NDUFA6; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 [KO:K03950 ]
106844493 NDUFA7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 isoform X5 [KO:K03951 ]
106837867 NDUFA8; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 [KO:K03952 ]
106831495 NDUFA9; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial [KO:K03953 ]
106832206 NDUFA10; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial isoform X1 [KO:K03954 ]
106846147 NDUFAB1; acyl carrier protein, mitochondrial isoform X2 [KO:K03955 ]
106832748 NDUFA11; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 [KO:K03956 ]
106831170 NDUFA12; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 isoform X1 [KO:K11352 ]
106825466 NDUFA13; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 isoform X1 [KO:K11353 ]
106825375 NDUFB1; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 [KO:K03957 ]
106842621 NDUFB2; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial [KO:K03958 ]
106823500 NDUFB3; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 [KO:K03959 ]
106823734 NDUFB4; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 [KO:K03960 ]
106829307 NDUFB5; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial [KO:K03961 ]
106841469 NDUFB6; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 [KO:K03962 ]
106844306 NDUFB7; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 isoform X2 [KO:K03963 ]
106846749 NDUFB8; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial [KO:K03964 ]
106839361 NDUFB9; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 [KO:K03965 ]
106836226 NDUFB10; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 [KO:K03966 ]
106847989 NDUFB11; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial [KO:K11351 ]
106827589 NDUFS2; NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial [KO:K03935 ] [EC:7.1.1.2 ]
106844019 NDUFS3; NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial isoform X1 [KO:K03936 ] [EC:7.1.1.2 ]
106843348 NDUFS4; NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial [KO:K03937 ]
106830578 NDUFS5; NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 isoform X2 [KO:K03938 ]
106835886 NDUFS6; NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial [KO:K03939 ]
106834185 NDUFS7; NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial isoform X2 [KO:K03940 ] [EC:7.1.1.2 ]
106844280 NDUFS8; NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial [KO:K03941 ] [EC:7.1.1.2 ]
106838418 NDUFC1; NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial [KO:K03967 ]
106835869 SDHA; succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial isoform X1 [KO:K00234 ] [EC:1.3.5.1 ]
106827983 SDHB; succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial [KO:K00235 ] [EC:1.3.5.1 ]
106827584 SDHC; succinate dehydrogenase cytochrome b560 subunit, mitochondrial isoform X1 [KO:K00236 ]
106840217 SDHD; succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial isoform X1 [KO:K00237 ]
106830662 cytochrome b-c1 complex subunit 1, mitochondrial isoform X1 [KO:K00414 ]
106822600 cytochrome b-c1 complex subunit 6, mitochondrial isoform X1 [KO:K00416 ]
106829176 cytochrome c oxidase subunit 4 isoform 1, mitochondrial [KO:K02263 ]
106833711 cytochrome c oxidase subunit 4 isoform 2, mitochondrial isoform X2 [KO:K02263 ]
123285498 LOW QUALITY PROTEIN: cytochrome c oxidase subunit 6C-like [KO:K02268 ]
106842554 cytochrome c oxidase subunit 7A-related protein, mitochondrial [KO:K02270 ]
106831232 ATP5F1C; ATP synthase subunit gamma, mitochondrial isoform X1 [KO:K02136 ]
106828604 ATP5PB; ATP synthase F(0) complex subunit B1, mitochondrial [KO:K02127 ]
106828058 ATP5MC2; ATP synthase F(0) complex subunit C2, mitochondrial [KO:K02128 ]
106837906 ATP5MC3; ATP synthase F(0) complex subunit C3, mitochondrial isoform X1 [KO:K02128 ]
106826529 ATP5MC1; ATP synthase F(0) complex subunit C1, mitochondrial isoform X1 [KO:K02128 ]
106842470 ATP5PF; ATP synthase-coupling factor 6, mitochondrial [KO:K02131 ]
106834658 VDAC1; voltage-dependent anion-selective channel protein 1 [KO:K05862 ]
106837945 LOW QUALITY PROTEIN: voltage-dependent anion-selective channel protein 1-like [KO:K05862 ]
106838857 TOMM40; mitochondrial import receptor subunit TOM40 homolog [KO:K11518 ]
106827586 TOMM40L; mitochondrial import receptor subunit TOM40B isoform X1 [KO:K11518 ]
106845190 CALML6; LOW QUALITY PROTEIN: calmodulin-like protein 6 [KO:K02183 ]
106847712 PPP3CC; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X4 [KO:K04348 ] [EC:3.1.3.16 ]
106834431 PPP3CA; LOW QUALITY PROTEIN: serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform [KO:K04348 ] [EC:3.1.3.16 ]
106842388 PPP3CB; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X3 [KO:K04348 ] [EC:3.1.3.16 ]
106838669 FASLG; tumor necrosis factor ligand superfamily member 6 [KO:K04389 ]
106822180 FAS; tumor necrosis factor receptor superfamily member 6 isoform X2 [KO:K04390 ]
106826047 TRAP1; LOW QUALITY PROTEIN: heat shock protein 75 kDa, mitochondrial [KO:K09488 ]
106843557 VDAC2; voltage-dependent anion-selective channel protein 2 [KO:K15040 ]
106828962 VDAC3; voltage-dependent anion-selective channel protein 3 isoform X1 [KO:K15041 ]
106827252 APAF1; apoptotic protease-activating factor 1 isoform X1 [KO:K02084 ]
106827069 MAP1LC3B; microtubule-associated proteins 1A/1B light chain 3B [KO:K10435 ]
106842411 MAP1LC3C; microtubule-associated proteins 1A/1B light chain 3C [KO:K10435 ]
106824938 MAP1LC3A; microtubule-associated proteins 1A/1B light chain 3A [KO:K10435 ]
106843101 TANK; TRAF family member-associated NF-kappa-B activator isoform X3 [KO:K12650 ]
106832810 RB1CC1; RB1-inducible coiled-coil protein 1 isoform X1 [KO:K17589 ]
106843993 AMBRA1; activating molecule in BECN1-regulated autophagy protein 1 isoform X1 [KO:K17985 ]
106826990 ATG14; beclin 1-associated autophagy-related key regulator [KO:K17889 ]
106832625 ATG2B; LOW QUALITY PROTEIN: autophagy-related protein 2 homolog B [KO:K17906 ]
106833611 ATG2A; autophagy-related protein 2 homolog A isoform X1 [KO:K17906 ]
106835357 WIPI1; WD repeat domain phosphoinositide-interacting protein 1 isoform X1 [KO:K17908 ]
106846343 WIPI2; WD repeat domain phosphoinositide-interacting protein 2 isoform X1 [KO:K17908 ]
106827710 ZFYVE1; zinc finger FYVE domain-containing protein 1 isoform X2 [KO:K17603 ]
106840518 RAC1; ras-related C3 botulinum toxin substrate 1 isoform X1 [KO:K04392 ]
106823264 CHMP2B; charged multivesicular body protein 2b isoform X1 [KO:K12192 ]
106831483 TNFRSF1A; tumor necrosis factor receptor superfamily member 1A [KO:K03158 ]
106836661 TNFRSF1B; tumor necrosis factor receptor superfamily member 1B isoform X1 [KO:K05141 ]
106821745 DNAH1; LOW QUALITY PROTEIN: dynein axonemal heavy chain 1 [KO:K10408 ]
106827374 DNAH7; LOW QUALITY PROTEIN: dynein axonemal heavy chain 7 [KO:K10408 ]
106845772 DNAH9; LOW QUALITY PROTEIN: dynein axonemal heavy chain 9 [KO:K10408 ]
106838613 DNAH6; LOW QUALITY PROTEIN: dynein axonemal heavy chain 6 [KO:K10408 ]
106829637 DNAH5; LOW QUALITY PROTEIN: dynein axonemal heavy chain 5 [KO:K10408 ]
106845334 DNAH17; LOW QUALITY PROTEIN: dynein axonemal heavy chain 17 [KO:K10408 ]
106830557 DNALI1; axonemal dynein light intermediate polypeptide 1 [KO:K10410 ]
106830251 DNAI2; dynein axonemal intermediate chain 2 isoform X1 [KO:K11143 ]
106843233 CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X1 [KO:K04515 ] [EC:2.7.11.17 ]
106843543 CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X1 [KO:K04515 ] [EC:2.7.11.17 ]
106822866 CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1 [KO:K04515 ] [EC:2.7.11.17 ]
106838495 CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1 [KO:K04515 ] [EC:2.7.11.17 ]
106844271 LRP5; low-density lipoprotein receptor-related protein 5 isoform X1 [KO:K03068 ]
106834121 LRP6; low-density lipoprotein receptor-related protein 6 isoform X1 [KO:K03068 ]
106845228 DVL1; LOW QUALITY PROTEIN: segment polarity protein dishevelled homolog DVL-1 [KO:K02353 ]
106844176 DVL2; segment polarity protein dishevelled homolog DVL-2 isoform X1 [KO:K02353 ]
106834527 DVL3; segment polarity protein dishevelled homolog DVL-3 [KO:K02353 ]
123278957 FRAT2; LOW QUALITY PROTEIN: GSK-3-binding protein FRAT2 [KO:K03096 ]
106834222 APC2; LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2 [KO:K02085 ]
106832251 APC; LOW QUALITY PROTEIN: adenomatous polyposis coli protein [KO:K02085 ]
106831014 AGER; advanced glycosylation end product-specific receptor isoform X1 [KO:K19722 ]
106825951 NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X1 [KO:K02580 ]
106827389 CSF1; macrophage colony-stimulating factor 1 isoform X1 [KO:K05453 ]
Compound
C01245 D-myo-Inositol 1,4,5-trisphosphate
C04549 1-Phosphatidyl-1D-myo-inositol 3-phosphate
C04599 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
C11310 1-Methyl-4-phenylpyridinium
C16514 Amyloid beta protein 40
C16515 Amyloid beta protein 42
C21011 [Protein]-N(epsilon)-(carboxymethyl)lysine
C21012 [Protein]-N(epsilon)-(carboxyethyl)lysine
Reference
Authors
Gan L, Cookson MR, Petrucelli L, La Spada AR
Title
Converging pathways in neurodegeneration, from genetics to mechanisms.
Journal
Reference
Authors
Dugger BN, Dickson DW
Title
Pathology of Neurodegenerative Diseases.
Journal
Reference
Authors
Jellinger KA
Title
Basic mechanisms of neurodegeneration: a critical update.
Journal
Reference
Authors
Jellinger KA
Title
Recent advances in our understanding of neurodegeneration.
Journal
Reference
Authors
Van Bulck M, Sierra-Magro A, Alarcon-Gil J, Perez-Castillo A, Morales-Garcia JA
Title
Novel Approaches for the Treatment of Alzheimer's and Parkinson's Disease.
Journal
Reference
Authors
Ross CA, Poirier MA
Title
Protein aggregation and neurodegenerative disease.
Journal
Reference
Authors
Soto C, Pritzkow S
Title
Protein misfolding, aggregation, and conformational strains in neurodegenerative diseases.
Journal
Reference
Authors
Dantuma NP, Bott LC
Title
The ubiquitin-proteasome system in neurodegenerative diseases: precipitating factor, yet part of the solution.
Journal
Reference
Authors
Zheng C, Geetha T, Babu JR
Title
Failure of ubiquitin proteasome system: risk for neurodegenerative diseases.
Journal
Reference
Authors
Park H, Kang JH, Lee S
Title
Autophagy in Neurodegenerative Diseases: A Hunter for Aggregates.
Journal
Reference
Authors
Malik BR, Maddison DC, Smith GA, Peters OM
Title
Autophagic and endo-lysosomal dysfunction in neurodegenerative disease.
Journal
Reference
Authors
Metaxakis A, Ploumi C, Tavernarakis N
Title
Autophagy in Age-Associated Neurodegeneration.
Journal
Reference
Authors
Vidal RL, Matus S, Bargsted L, Hetz C
Title
Targeting autophagy in neurodegenerative diseases.
Journal
Reference
Authors
Menzies FM, Fleming A, Caricasole A, Bento CF, Andrews SP, Ashkenazi A, Fullgrabe J, Jackson A, Jimenez Sanchez M, Karabiyik C, Licitra F, Lopez Ramirez A, Pavel M, Puri C, Renna M, Ricketts T, Schlotawa L, Vicinanza M, Won H, Zhu Y, Skidmore J, Rubinsztein DC
Title
Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities.
Journal
Reference
Authors
Chu CT
Title
Mechanisms of selective autophagy and mitophagy: Implications for neurodegenerative diseases.
Journal
Reference
Authors
Kim I, Xu W, Reed JC
Title
Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities.
Journal
Reference
Authors
Doyle KM, Kennedy D, Gorman AM, Gupta S, Healy SJ, Samali A
Title
Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders.
Journal
Reference
Authors
Halliday M, Hughes D, Mallucci GR
Title
Fine-tuning PERK signaling for neuroprotection.
Journal
Reference
Authors
Rozpedek-Kaminska W, Siwecka N, Wawrzynkiewicz A, Wojtczak R, Pytel D, Diehl JA, Majsterek I
Title
The PERK-Dependent Molecular Mechanisms as a Novel Therapeutic Target for Neurodegenerative Diseases.
Journal
Reference
Authors
Hetz C, Mollereau B
Title
Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases.
Journal
Reference
Authors
Bezprozvanny I
Title
Calcium signaling and neurodegenerative diseases.
Journal
Reference
Authors
Ureshino RP, Erustes AG, Bassani TB, Wachilewski P, Guarache GC, Nascimento AC, Costa AJ, Smaili SS, Pereira GJDS
Title
The Interplay between Ca(2+) Signaling Pathways and Neurodegeneration.
Journal
Reference
Authors
Golpich M, Amini E, Mohamed Z, Azman Ali R, Mohamed Ibrahim N, Ahmadiani A
Title
Mitochondrial Dysfunction and Biogenesis in Neurodegenerative diseases: Pathogenesis and Treatment.
Journal
Reference
Authors
Morfini GA, Burns M, Binder LI, Kanaan NM, LaPointe N, Bosco DA, Brown RH Jr, Brown H, Tiwari A, Hayward L, Edgar J, Nave KA, Garberrn J, Atagi Y, Song Y, Pigino G, Brady ST
Title
Axonal transport defects in neurodegenerative diseases.
Journal
Reference
Authors
Gibbs KL, Greensmith L, Schiavo G
Title
Regulation of Axonal Transport by Protein Kinases.
Journal
Reference
Authors
Millecamps S, Julien JP
Title
Axonal transport deficits and neurodegenerative diseases.
Journal
Reference
Authors
Sleigh JN, Rossor AM, Fellows AD, Tosolini AP, Schiavo G
Title
Axonal transport and neurological disease.
Journal
Reference
Authors
Perlson E, Maday S, Fu MM, Moughamian AJ, Holzbaur EL
Title
Retrograde axonal transport: pathways to cell death?
Journal
Related pathway
eai04141 Protein processing in endoplasmic reticulum
eai04933 AGE-RAGE signaling pathway in diabetic complications
KO pathway
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