KEGG   ORTHOLOGY: K04249
Entry
K04249                      KO                                     
Symbol
TSHR
Name
thyrotropin receptor
Pathway
map04024  cAMP signaling pathway
map04080  Neuroactive ligand-receptor interaction
map04918  Thyroid hormone synthesis
map04923  Regulation of lipolysis in adipocytes
map05320  Autoimmune thyroid disease
Disease
H00250  Congenital nongoitrous hypothyroidism (CHNG)
H01269  Congenital hyperthyroidism
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    K04249  TSHR; thyrotropin receptor
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04249  TSHR; thyrotropin receptor
 09150 Organismal Systems
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    K04249  TSHR; thyrotropin receptor
   04918 Thyroid hormone synthesis
    K04249  TSHR; thyrotropin receptor
 09160 Human Diseases
  09163 Immune disease
   05320 Autoimmune thyroid disease
    K04249  TSHR; thyrotropin receptor
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04249  TSHR; thyrotropin receptor
G protein-coupled receptors [BR:ko04030]
 Rhodopsin family
  Peptide
   Thyrotropin
    K04249  TSHR; thyrotropin receptor
Other DBs
GO: 0004996
Genes
HSA: 7253(TSHR)
PTR: 453077(TSHR)
PPS: 100972767(TSHR)
GGO: 101125784(TSHR)
PON: 100937088(TSHR)
NLE: 100607314(TSHR)
MCC: 574251(TSHR)
MCF: 102127039(TSHR)
CSAB: 103229438(TSHR)
CATY: 105590920(TSHR)
PANU: 101019180(TSHR)
TGE: 112628691(TSHR)
RRO: 104663334(TSHR)
RBB: 108530805(TSHR)
TFN: 117069240(TSHR)
PTEH: 111521619(TSHR)
CJC: 100407112(TSHR)
SBQ: 101037988(TSHR)
CSYR: 103259533(TSHR)
MMUR: 105867868(TSHR)
LCAT: 123640202(TSHR)
OGA: 100965380(TSHR)
MMU: 22095(Tshr)
MCAL: 110306948(Tshr)
MPAH: 110324476(Tshr)
RNO: 25360(Tshr)
MCOC: 116080136(Tshr)
MUN: 110561821(Tshr)
CGE: 100775040(Tshr)
MAUA: 101843573(Tshr)
PLEU: 114698925(Tshr)
MORG: 121434457 121452518(Tshr)
AAMP: 119819368(Tshr)
NGI: 103736397(Tshr)
HGL: 101718949(Tshr)
CPOC: 100721620(Tshr)
CCAN: 109680770
DORD: 105984073(Tshr)
DSP: 122118764(Tshr)
NCAR: 124977009
OCU: 100353965(TSHR)
OPI: 101519121(TSHR)
TUP: 102481319(TSHR)
CFA: 403968(TSHR)
CLUD: 112657489(TSHR)
VVP: 112934899(TSHR)
VLG: 121492425(TSHR)
AML: 100476960(TSHR)
UMR: 103670618(TSHR)
UAH: 113270272(TSHR)
UAR: 123798926(TSHR)
ELK: 111148625
LLV: 125105218
MPUF: 101683590(TSHR)
ORO: 101370481(TSHR)
EJU: 114205876(TSHR)
ZCA: 113908540(TSHR)
MLX: 118002568(TSHR)
FCA: 493842(TSHR)
PYU: 121032135(TSHR)
PBG: 122469405(TSHR)
PTG: 102962400(TSHR)
PPAD: 109274402(TSHR)
AJU: 106983585(TSHR)
HHV: 120248618(TSHR)
BTA: 281553(TSHR)
BOM: 102273230(TSHR)
BIU: 109565398(TSHR)
BBUB: 102403395(TSHR)
CHX: 102174848(TSHR)
OAS: 443428(TSHR)
ODA: 120852654(TSHR)
CCAD: 122443923(TSHR)
SSC: 397560(TSHR)
CFR: 102506391(TSHR)
CBAI: 105069684(TSHR)
CDK: 105086050(TSHR)
VPC: 102542465(TSHR)
BACU: 103007910(TSHR)
LVE: 103074120(TSHR)
OOR: 101276553(TSHR)
DLE: 111175908(TSHR)
PCAD: 102992777(TSHR)
PSIU: 116750018(TSHR)
ECB: 100052603(TSHR) 111770367(TSHR) 111772111
EPZ: 103561891(TSHR)
EAI: 106834829(TSHR)
MYB: 102247607(TSHR)
MYD: 102757126(TSHR)
MMYO: 118664849(TSHR)
MLF: 102425004(TSHR)
MNA: 107542654(TSHR)
PKL: 118714500(TSHR)
HAI: 109384686(TSHR)
DRO: 112311491(TSHR)
SHON: 118976802(TSHR)
AJM: 119056396(TSHR)
PDIC: 114492700(TSHR)
PHAS: 123808451(TSHR)
MMF: 118638548(TSHR)
RFQ: 117022834(TSHR)
PALE: 102879305(TSHR)
PGIG: 120619571(TSHR)
PVP: 105290108(TSHR)
RAY: 107506702(TSHR)
MJV: 108407926(TSHR)
TOD: 119238124
SARA: 101549819(TSHR)
LAV: 100659046(TSHR)
TMU: 101342131
DNM: 101441265(TSHR)
MDO: 100021427(TSHR)
GAS: 123235883(TSHR)
SHR: 100918071(TSHR)
PCW: 110200916(TSHR)
OAA: 100073918(TSHR)
GGA: 428900(TSHR)
PCOC: 116228763(TSHR)
MGP: 100548187(TSHR)
CJO: 107315169(TSHR)
NMEL: 110401706(TSHR)
APLA: 101798978(TSHR)
ACYG: 106044543(TSHR)
AFUL: 116489990(TSHR)
TGU: 100221875(TSHR)
LSR: 110477263(TSHR)
SCAN: 103826493(TSHR)
PMOA: 120500476(TSHR)
OTC: 121333920(TSHR)
PRUF: 121356010(TSHR)
GFR: 102042388(TSHR)
FAB: 101812703(TSHR)
PHI: 102111924(TSHR)
PMAJ: 107205537(TSHR)
CCAE: 111929929(TSHR)
CCW: 104685667(TSHR)
CBRC: 103612101(TSHR)
ETL: 114068347(TSHR)
ZAB: 102074868(TSHR)
FPG: 101919866(TSHR)
FCH: 102049876(TSHR)
CLV: 102092407(TSHR)
EGZ: 104133261(TSHR)
NNI: 104023418(TSHR)
PLET: 104616092(TSHR)
PCRI: 104032982
ACUN: 113480649(TSHR)
TALA: 104363766(TSHR)
PADL: 103912982(TSHR)
ACHC: 115337294(TSHR)
HALD: 104319620(TSHR)
CCRI: 104158771(TSHR)
CSTI: 104552464(TSHR)
EHS: 104508827(TSHR)
CMAC: 104479529
FGA: 104076198(TSHR)
GSTE: 104264511(TSHR)
LDI: 104347836(TSHR)
MNB: 103771365(TSHR)
OHA: 104332872(TSHR)
AAM: 106483120(TSHR)
AROW: 112977034(TSHR)
NPD: 112955004(TSHR)
DNE: 112989995(TSHR)
ASN: 102379889(TSHR)
AMJ: 102559305(TSHR)
CPOO: 109321576(TSHR)
GGN: 109298559(TSHR)
PSS: 102448787(TSHR)
CMY: 102935714(TSHR)
CPIC: 101934096(TSHR)
TST: 117876481(TSHR)
CABI: 116835104(TSHR)
MRV: 120402843(TSHR)
ACS: 100565546(tshr)
PVT: 110089516(TSHR)
SUND: 121926770(TSHR)
PBI: 103060796(TSHR)
PMUR: 107295475(TSHR)
TSR: 106547172
PGUT: 117666130(TSHR)
VKO: 123026635(TSHR)
PMUA: 114591338(TSHR)
ZVI: 118081349(TSHR)
GJA: 107123703(TSHR)
STOW: 125427529(TSHR)
XTR: 100492843(tshr)
NPR: 108803865
RTEM: 120921134(TSHR)
BBUF: 120981652(TSHR)
BGAR: 122921558(TSHR)
DRE: 560609(tshr)
CAUA: 113121244
PPRM: 120485879(tshr)
MAMB: 125261047(tshr)
IPU: 100304626(tshr)
PHYP: 113528721
SMEO: 124401291(tshr)
TFD: 113637399(tshr)
AMEX: 103024692(tshr)
EEE: 113571056(tshr)
TRU: 101078625(tshr)
LCO: 104934989 104940353(tshr)
CGOB: 115003680(tshr) 115016552
ELY: 117269946 117270448(tshr)
EFO: 125897067(tshr) 125905802
PLEP: 121955334(tshr) 121960045
SLUC: 116041479 116041966(tshr)
ECRA: 117959694 117961479(tshr)
PFLV: 114570588 114573645(tshr)
GAT: 120807773(tshr) 120831952
PPUG: 119195068(tshr) 119226629
MSAM: 119909592(tshr) 119915152
CUD: 121521980(tshr) 121524828
ALAT: 119013122(tshr) 119029429
MZE: 101484362 101487214(tshr)
ONL: 100534416(tshr) 100700258
OAU: 116315529(tshr) 116319150
OLA: 101170361 101170888(tshr)
OML: 112140470 112157598(tshr)
XMA: 102226272(tshr) 102227717
XCO: 114149033 114158998(tshr)
XHE: 116724735 116734541(tshr)
PRET: 103457814(tshr) 103473163
GAF: 122825322(tshr) 122847106
CVG: 107090086(tshr) 107098490
CTUL: 119783501(tshr)
GMU: 124872071 124881998(tshr)
NFU: 107378162(tshr) 107395090
KMR: 108231850(tshr) 108246452
NWH: 119418412(tshr) 119425085
AOCE: 111569120(tshr) 111579141
MCEP: 124997009 124998990(tshr)
CSEM: 103380719(tshr)
POV: 109632395(tshr) 109637608
SSEN: 122761046 122784052(tshr)
HHIP: 117758346(tshr) 117771414
HSP: 118099953(tshr) 118126024
SDU: 111221097 111235988(tshr)
SLAL: 111659638 111672643(tshr)
XGL: 120789202(tshr) 120806637
HCQ: 109508158
MALB: 109960698 109970542(tshr)
BSPL: 114849697(tshr) 114867237
SFM: 108922264(tshr)
PKI: 111841762
LOC: 102687834(tshr)
LCM: 102351480(TSHR)
CMK: 103186808(tshr)
RTP: 109925594(tshr)
BFO: 118409455
BBEL: 109470340
SCLV: 120334534
APLC: 110979502
SKO: 100377796
DME: Dmel_CG7665(Lgr1)
DER: 6552118
DSE: 6616693
DSI: Dsimw501_GD19184(Dsim_GD19184)
DSR: 110188216
DPO: 6897829
DPE: 6594527
DMN: 108157437
DWI: 6649415
DGR: 6568441
DAZ: 108621498
DNV: 108652111
DHE: 111598500
DVI: 6632944
CCAT: 101451520
BOD: 106622289
MDE: 101893701
SCAC: 106082845
LCQ: 111675991
LSQ: 119613805
HIS: 119660184
AGA: AgaP_AGAP004035(GPRFSH)
ACOZ: 120950814
AARA: 120895353
ASTE: 118507431
AAG: 5564685
AALB: 109429338
CPII: 120425720
CNS: 116338579
BCOO: 119080404
DPA: 109544186
CSET: 123306571
LDC: 111505735
NVL: 108566343
BMOR: 692585(Lgr)
BMAN: 114247249
MSEX: 115446557
BANY: 112057894
PMAC: 106719292
PPOT: 106108798
PXU: 106119714
PRAP: 110997159
ZCE: 119838672
HAW: 110383514
HZE: 124637531
TNL: 113491988
SLIU: 111347930
OFU: 114352213
DNX: 107166703
AGS: 114122071
DCI: 103505087
FCD: 110843509
DPX: DAPPUDRAFT_290661(LGR1)
DMK: 116928449
PJA: 122259881
DSV: 119443058
RSAN: 119382488
RMP: 119175462
VJA: 111259024
TUT: 107367504
DPTE: 113789329
DFR: 124491689
CSCU: 111634507
SDM: 118186681
PCAN: 112570446
BGT: 106056314
GAE: 121370012
HRF: 124111929
MYI: 110442374
PMAX: 117324133
MMER: 123532311
LAK: 106161863
ADF: 107339069
AQU: 100636996
 » show all
Reference
PMID:2610690
  Authors
Libert F, Lefort A, Gerard C, Parmentier M, Perret J, Ludgate M, Dumont JE, Vassart G
  Title
Cloning, sequencing and expression of the human thyrotropin (TSH) receptor: evidence for binding of autoantibodies.
  Journal
Biochem Biophys Res Commun 165:1250-5 (1989)
DOI:10.1016/0006-291X(89)92736-8
  Sequence
[hsa:7253]
LinkDB

DBGET integrated database retrieval system