KEGG   NETWORK: N01859
Entry
N01859                      Network                                
Name
Anterograde axonal/dendrite transport, Kinesin-1
Definition
(TRAK1/2) == (KIF5+KLC) == (TUBA+TUBB)
  Expanded
(22906,66008) == ((3798,3799,3800)+(3831,64837,147700,89953)) == ((7846,10376,84790,7278,113457,112714,7277,51807)+(203068,81027,7280,347733,10381,10382,10383,84617,347688))
Class
nt06541 Cytoskeleton in neurons
Type
Reference
Gene
22906  TRAK1; trafficking kinesin protein 1
66008  TRAK2; trafficking kinesin protein 2
3798  KIF5A; kinesin family member 5A
3799  KIF5B; kinesin family member 5B
3800  KIF5C; kinesin family member 5C
3831  KLC1; kinesin light chain 1
64837  KLC2; kinesin light chain 2
147700  KLC3; kinesin light chain 3
89953  KLC4; kinesin light chain 4
7846  TUBA1A; tubulin alpha 1a
10376  TUBA1B; tubulin alpha 1b
84790  TUBA1C; tubulin alpha 1c
7278  TUBA3C; tubulin alpha 3c
113457  TUBA3D; tubulin alpha 3d
112714  TUBA3E; tubulin alpha 3e
7277  TUBA4A; tubulin alpha 4a
51807  TUBA8; tubulin alpha 8
203068  TUBB; tubulin beta class I
81027  TUBB1; tubulin beta 1 class VI
7280  TUBB2A; tubulin beta 2A class IIa
347733  TUBB2B; tubulin beta 2B class IIb
10381  TUBB3; tubulin beta 3 class III
10382  TUBB4A; tubulin beta 4A class IVa
10383  TUBB4B; tubulin beta 4B class IVb
84617  TUBB6; tubulin beta 6 class V
347688  TUBB8; tubulin beta 8 class VIII
Reference
PMID:34033795
  Authors
Aiken J, Holzbaur ELF
  Title
Cytoskeletal regulation guides neuronal trafficking to effectively supply the synapse.
  Journal
Curr Biol 31:R633-R650 (2021)
DOI:10.1016/j.cub.2021.02.024
Reference
PMID:34796656
  Authors
Fan R, Lai KO
  Title
Understanding how kinesin motor proteins regulate postsynaptic function in neuron.
  Journal
FEBS J 289:2128-2144 (2022)
DOI:10.1111/febs.16285
Reference
PMID:21092854
  Authors
Hirokawa N, Niwa S, Tanaka Y
  Title
Molecular motors in neurons: transport mechanisms and roles in brain function, development, and disease.
  Journal
Neuron 68:610-38 (2010)
DOI:10.1016/j.neuron.2010.09.039
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