KEGG   REACTION: R00072
Entry
R00072                      Reaction                               
Name
thiamine-aldehyde:oxygen 5-oxidoreductase
Definition
Thiamine aldehyde + Oxygen + H2O <=> Hydrogen peroxide + Thiamine acetic acid
Equation
Comment
second step of two-step reaction (see R02132, R00033+R00072)
following after R00033
Reaction class
RC00080  C02892_C05856
RC02755  C00007_C00027
Enzyme
Pathway
rn00730  Thiamine metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.3  With oxygen as acceptor
    1.1.3.23
     R00072  Thiamine aldehyde + Oxygen + H2O <=> Hydrogen peroxide + Thiamine acetic acid
Reference
1  [PMID:2988447]
  Authors
Gomez-Moreno C, Edmondson DE.
  Title
Evidence for an aldehyde intermediate in the catalytic mechanism of thiamine oxidase.
  Journal
Arch Biochem Biophys 239:46-52 (1985)
DOI:10.1016/0003-9861(85)90810-0
LinkDB

KEGG   RCLASS: RC00080
Entry
RC00080                     RClass                                 
Definition
C4a-C6a:*-O6a:C1b+O4a-C1b+O6a
Reactant pair
Related class
Reaction
Enzyme
1.1.3.17        1.1.3.23        1.2.1.3         1.2.1.4         
1.2.1.5         1.2.1.8         1.2.1.15        1.2.1.16        
1.2.1.19        1.2.1.20        1.2.1.21        1.2.1.24        
1.2.1.26        1.2.1.29        1.2.1.31        1.2.1.39        
1.2.1.47        1.2.1.48        1.2.1.53        1.2.1.54        
1.2.1.63        1.2.1.69        1.2.1.71        1.2.1.73        
1.2.1.77        1.2.1.79        1.2.1.83        1.2.1.88        
1.2.1.91        1.2.1.95        1.2.1.99        1.2.1.-         
1.2.3.1         1.2.3.7         1.2.-.-         1.14.14.3       
1.14.14.49
Pathway
rn00040  Pentose and glucuronate interconversions
rn00053  Ascorbate and aldarate metabolism
rn00071  Fatty acid degradation
rn00073  Cutin, suberine and wax biosynthesis
rn00250  Alanine, aspartate and glutamate metabolism
rn00260  Glycine, serine and threonine metabolism
rn00310  Lysine degradation
rn00330  Arginine and proline metabolism
rn00340  Histidine metabolism
rn00350  Tyrosine metabolism
rn00360  Phenylalanine metabolism
rn00362  Benzoate degradation
rn00380  Tryptophan metabolism
rn00410  beta-Alanine metabolism
rn00430  Taurine and hypotaurine metabolism
rn00440  Phosphonate and phosphinate metabolism
rn00470  D-Amino acid metabolism
rn00625  Chloroalkane and chloroalkene degradation
rn00630  Glyoxylate and dicarboxylate metabolism
rn00640  Propanoate metabolism
rn00643  Styrene degradation
rn00650  Butanoate metabolism
rn00670  One carbon pool by folate
rn00730  Thiamine metabolism
rn00760  Nicotinate and nicotinamide metabolism
rn00770  Pantothenate and CoA biosynthesis
rn00930  Caprolactam degradation
rn00980  Metabolism of xenobiotics by cytochrome P450
rn00982  Drug metabolism - cytochrome P450
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
rn01230  Biosynthesis of amino acids
rn01240  Biosynthesis of cofactors
RModule
RM017  Ring cleavage via Baeyer-Villiger oxidation
RM025  Conversion of amino acid moiety to carboxyl group
Orthology
K00128  aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
K00129  aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5]
K00130  betaine-aldehyde dehydrogenase [EC:1.2.1.8]
K00135  succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
K00137  aminobutyraldehyde dehydrogenase [EC:1.2.1.19]
K00139  succinate-semialdehyde dehydrogenase [EC:1.2.1.24]
K00143  L-2-aminoadipate reductase [EC:1.2.1.95]
K00146  phenylacetaldehyde dehydrogenase [EC:1.2.1.39]
K00149  aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3]
K00157  aldehyde oxidase [EC:1.2.3.1]
K00206  phosphonoacetaldehyde dehydrogenase [EC:1.2.1.-]
K00294  1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88]
K00494  alkanal monooxygenase alpha chain [EC:1.14.14.3]
K02618  oxepin-CoA hydrolase / 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase [EC:3.3.2.12 1.2.1.91]
K06447  succinylglutamic semialdehyde dehydrogenase [EC:1.2.1.71]
K07248  lactaldehyde dehydrogenase / glycolaldehyde dehydrogenase [EC:1.2.1.22 1.2.1.21]
K08324  succinate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.24]
K09472  4-(gamma-glutamylamino)butanal dehydrogenase [EC:1.2.1.99]
K11817  indole-3-acetaldehyde oxidase [EC:1.2.3.7]
K12254  4-guanidinobutyraldehyde dehydrogenase / NAD-dependent aldehyde dehydrogenase [EC:1.2.1.54 1.2.1.-]
K13774  citronellol/citronellal dehydrogenase
K13775  citronellol/citronellal dehydrogenase
K13821  RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
K13877  2,5-dioxopentanoate dehydrogenase [EC:1.2.1.26]
K14085  aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3]
K14519  NADP-dependent aldehyde dehydrogenase [EC:1.2.1.4]
K15514  3,4-dehydroadipyl-CoA semialdehyde dehydrogenase [EC:1.2.1.77]
K15786  aspartate-semialdehyde dehydrogenase [EC:1.2.1.-]
K15854  alkanal monooxygenase beta chain [EC:1.14.14.3]
K17755  choline oxidase [EC:1.1.3.17]
K17761  succinate-semialdehyde dehydrogenase, mitochondrial [EC:1.2.1.24]
K19588  2,5-dioxopentanoate dehydrogenase [EC:1.2.1.26]
K19699  sulfoacetaldehyde dehydrogenase [EC:1.2.1.73]
K19700  3-succinoylsemialdehyde-pyridine dehydrogenase [EC:1.2.1.83]
K19962  6-oxohexanoate dehydrogenase [EC:1.2.1.63]
K22187  alpha-ketoglutaric semialdehyde dehydrogenase [EC:1.2.1.-]
K22417  benzaldehyde dehydrogenase (NAD+) / indole-3-acetaldehyde oxidase [EC:1.2.1.28 1.2.3.7]
K26061  L-aminoadipate-semialdehyde dehydrogenase

DBGET integrated database retrieval system