KEGG   REACTION: R00485
Entry
R00485                      Reaction                               
Name
L-asparagine amidohydrolase
Definition
L-Asparagine + H2O <=> L-Aspartate + Ammonia
Equation
C00152 + C00001 <=> C00049 + C00014
Reaction class
RC00010  C00049_C00152
RC02798  C00014_C00152
Enzyme
3.5.1.1         3.5.1.38        3.5.5.4
Pathway
rn00250  Alanine, aspartate and glutamate metabolism
rn00460  Cyanoamino acid metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.1
     R00485  L-Asparagine + H2O <=> L-Aspartate + Ammonia
    3.5.1.38
     R00485  L-Asparagine + H2O <=> L-Aspartate + Ammonia
   3.5.5  In nitriles
    3.5.5.4
     R00485  L-Asparagine + H2O <=> L-Aspartate + Ammonia
Orthology
K01424  L-asparaginase [EC:3.5.1.1]
K05597  glutamin-(asparagin-)ase [EC:3.5.1.38]
K13051  L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
Other DBs
RHEA: 21019
LinkDB

KEGG   RCLASS: RC00010
Entry
RC00010                     RClass                                 
Definition
C5a-C6a:N1a+*-*+O6a:C1b+O5a-C1b+O6a
Reactant pair
C00025_C00064    C00026_C00940    C00036_C02362
C00049_C00152    C00083_C06625    C00099_C19779
C00120_C01893    C00217_C00819    C00318_C02290
C00431_C00990    C00614_C02583    C00712_C19670
C00803_C01842    C00954_C02693    C01035_C03078
C01209_C21430    C02028_C04131    C02282_C06112
C02505_C07086    C02986_C21456    C03402_C06113
C03904_C03905    C05773_C19724    C06504_C19724
C21177_C21179    C21458_C21465
Related class
Reaction
R00021 R00093 R00114 R00253 R00256 R00257 R00269 R00348
R00482 R00483 R00485 R00573 R00575 R00578 R00768 R00986
R01072 R01231 R01579 R01716 R01922 R02273 R02540 R02622
R02938 R03096 R03180 R03804 R03905 R04212 R04341 R04463
R04558 R05224 R05225 R05815 R07456 R08244 R08855 R08956
R09195 R09537 R09598 R09599 R09648 R10089 R11209 R11515
R11559 R11560
Enzyme
1.4.1.13        1.4.1.14        1.4.7.1         2.4.2.14        
2.6.1.16        2.6.1.85        2.6.1.86        2.6.1.123       
3.5.1.1         3.5.1.2         3.5.1.3         3.5.1.4         
3.5.1.30        3.5.1.35        3.5.1.38        3.5.1.43        
3.5.1.44        3.5.1.50        3.5.1.73        3.5.1.99        
3.5.1.100       3.5.1.111       3.5.1.119       3.5.1.121       
3.5.1.122       3.5.1.-         3.5.5.4         4.1.3.27        
4.3.2.10        4.3.3.6         6.3.1.1         6.3.1.2         
6.3.1.4         6.3.4.2         6.3.5.1         6.3.5.2         
6.3.5.3         6.3.5.4         6.3.5.5         6.3.5.6         
6.3.5.7         6.3.5.9         6.3.5.10        6.3.5.11        
6.3.5.13        6.3.5.-
 » show all
Pathway
rn00250  Alanine, aspartate and glutamate metabolism
rn00253  Tetracycline biosynthesis
rn00310  Lysine degradation
rn00330  Arginine and proline metabolism
rn00360  Phenylalanine metabolism
rn00380  Tryptophan metabolism
rn00460  Cyanoamino acid metabolism
rn00470  D-Amino acid metabolism
rn00630  Glyoxylate and dicarboxylate metabolism
rn00643  Styrene degradation
rn00910  Nitrogen metabolism
rn00970  Aminoacyl-tRNA biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01230  Biosynthesis of amino acids
RModule
RM031  Oxime to acetate conversion
Orthology
K00264  glutamate synthase (NADH) [EC:1.4.1.14]
K00265  glutamate synthase (NADPH) large chain [EC:1.4.1.13]
K00266  glutamate synthase (NADPH) small chain [EC:1.4.1.13]
K00284  glutamate synthase (ferredoxin) [EC:1.4.7.1]
K00764  amidophosphoribosyltransferase [EC:2.4.2.14]
K00820  glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
K01424  L-asparaginase [EC:3.5.1.1]
K01425  glutaminase [EC:3.5.1.2]
K01426  amidase [EC:3.5.1.4]
K01506  5-aminopentanamidase [EC:3.5.1.30]
K01656  anthranilate synthase / indole-3-glycerol phosphate synthase [EC:4.1.3.27 4.1.1.48]
K01657  anthranilate synthase component I [EC:4.1.3.27]
K01658  anthranilate synthase component II [EC:4.1.3.27]
K01663  imidazole glycerol-phosphate synthase [EC:4.3.2.10]
K01664  para-aminobenzoate synthetase component II [EC:2.6.1.85]
K01665  para-aminobenzoate synthetase component I [EC:2.6.1.85]
K01914  aspartate--ammonia ligase [EC:6.3.1.1]
K01915  glutamine synthetase [EC:6.3.1.2]
K01937  CTP synthase [EC:6.3.4.2]
K01950  NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1]
K01951  GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
K01952  phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]
K01953  asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
K01954  carbamoyl-phosphate synthase [EC:6.3.5.5]
K01955  carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
K01956  carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
K02224  cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11]
K02232  adenosylcobyric acid synthase [EC:6.3.5.10]
K02433  aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
K02434  aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
K02435  aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
K02500  imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]
K02501  imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10]
K03330  glutamyl-tRNA(Gln) amidotransferase subunit E [EC:6.3.5.7]
K03342  para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase [EC:2.6.1.85 4.1.3.38]
K03865  glutamyl-tRNA(Gln) amidotransferase subunit F [EC:6.3.5.7]
K05597  glutamin-(asparagin-)ase [EC:3.5.1.38]
K06215  pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6]
K08590  2-oxoglutaramate amidase [EC:3.5.1.111]
K08681  pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6]
K09482  glutamyl-tRNA(Gln) amidotransferase subunit D [EC:6.3.5.7]
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
K11541  carbamoyl-phosphate synthase / aspartate carbamoyltransferase [EC:6.3.5.5 2.1.3.2]
K13051  L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
K13063  2-amino-4-deoxychorismate synthase [EC:2.6.1.86]
K13497  anthranilate synthase/phosphoribosyltransferase [EC:4.1.3.27 2.4.2.18]
K13501  anthranilate synthase / indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase [EC:4.1.3.27 4.1.1.48 5.3.1.24]
K13503  anthranilate synthase [EC:4.1.3.27]
K13566  omega-amidase [EC:3.5.1.3]
K13950  para-aminobenzoate synthetase [EC:2.6.1.85]
K14244  amidotransferase [EC:6.3.5.-]
K14662  protein N-terminal asparagine amidohydrolase [EC:3.5.1.121]
K20159  2-amino-4-deoxychorismate synthase [EC:2.6.1.86]
K21175  2-amino-4-deoxychorismate synthase, glutamine amidotransferase component [EC:2.6.1.86]
K21286  protein N-terminal glutamine amidohydrolase [EC:3.5.1.122]
K21801  indoleacetamide hydrolase [EC:3.5.1.-]
K23264  phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3]
K23265  phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
K23269  phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3]
K23270  phosphoribosylformylglycinamidine synthase subunit PurSL [EC:6.3.5.3]

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