KEGG   REACTION: R12400
Entry
R12400                      Reaction                               
Name
episterol:NADP+ 3-oxidoreductase
Definition
Episterone + NADPH + H+ <=> Episterol + NADP+
Equation
C22122 + C00005 + C00080 <=> C15777 + C00006
Reaction class
RC00144  C15777_C22122
Enzyme
1.1.1.270
Pathway
rn00100  Steroid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00917  Phytosterol biosynthesis, squalene 2,3-epoxide => campesterol/sitosterol
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.270
     R12400  Episterone + NADPH + H+ <=> Episterol + NADP+
IUBMB reaction hierarchy [BR:br08202]
 1. Oxidoreductase reactions
  1.1.1.270
   R12402  3beta-Hydroxysteroid <=> 3-Oxosteroid
    R12400  Episterol <=> Episterone
LinkDB

KEGG   RCLASS: RC00144
Entry
RC00144                     RClass                                 
Definition
C1y-C5x:*-*:C1x+C1x+O1a-C1x+C1x+O5x
Reactant pair
C00414_C00854    C00523_C00674    C00557_C02020
C00674_C07635    C00729_C00783    C00783_C02066
C01034_C03836    C01066_C03228    C01090_C01986
C01157_C01877    C01227_C20252    C01876_C02945
C01876_C03072    C03070_C03990    C03070_C17658
C03681_C13712    C03681_C15484    C03767_C04404
C03772_C04373    C03852_C03917    C03917_C12525
C05437_C22136    C05451_C05452    C05453_C05454
C05469_C05470    C05471_C05472    C05473_C05474
C05475_C05476    C05477_C05478    C05479_C05480
C05479_C11825    C09707_C15971    C13713_C18040
C15777_C22122    C15782_C22123    C15786_C15787
C15791_C15792    C15792_C15793    C15797_C15798
C15797_C16251    C15799_C15800    C15800_C15801
C16493_C16509    C18041_C18042    C18327_C18328
C18330_C18331    C18333_C18334    C21827_C21828
C22831_C22832
 » show all
Related class
Reaction
R02229 R02476 R02477 R02553 R02832 R03176 R03212 R03226
R03227 R04139 R04307 R04309 R04310 R04330 R04344 R04818
R04819 R04824 R04825 R04829 R04830 R04832 R04833 R04835
R04836 R04837 R04838 R04842 R04843 R04845 R04846 R06166
R06734 R07138 R07444 R07449 R07466 R07469 R07472 R07473
R07577 R07788 R08137 R08955 R08957 R08960 R08963 R09262
R09263 R09264 R09956 R09957 R10422 R10423 R11144 R11145
R11146 R11983 R12400 R12401 R12402 R12405 R12965 R13216
R13217
Enzyme
1.1.1.50        1.1.1.51        1.1.1.52        1.1.1.53        
1.1.1.145       1.1.1.147       1.1.1.152       1.1.1.163       
1.1.1.206       1.1.1.209       1.1.1.210       1.1.1.213       
1.1.1.226       1.1.1.236       1.1.1.239       1.1.1.245       
1.1.1.270       1.1.1.277       1.1.1.278       1.1.1.357       
1.1.1.391       1.1.1.392       1.1.1.393       1.1.1.-         
1.1.99.26       1.14.14.69      1.14.19.79      1.14.-.-
Pathway
rn00100  Steroid biosynthesis
rn00120  Primary bile acid biosynthesis
rn00140  Steroid hormone biosynthesis
rn00362  Benzoate degradation
rn00905  Brassinosteroid biosynthesis
rn00906  Carotenoid biosynthesis
rn00930  Caprolactam degradation
rn00960  Tropane, piperidine and pyridine alkaloid biosynthesis
rn00981  Insect hormone biosynthesis
rn00984  Steroid degradation
rn01056  Biosynthesis of type II polyketide backbone
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
RModule
RM017  Ring cleavage via Baeyer-Villiger oxidation
Orthology
K00037  3alpha-hydroxysteroid 3-dehydrogenase / chlordecone reductase [EC:1.1.1.50 1.1.1.357 1.1.1.225]
K00089  3alpha-hydroxysteroid 3-dehydrogenase [EC:1.1.1.213 1.1.1.357]
K04119  aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
K05296  3(or 17)beta-hydroxysteroid dehydrogenase [EC:1.1.1.51]
K05354  tropinone reductase II [EC:1.1.1.236]
K08081  tropinone reductase I [EC:1.1.1.206]
K09588  3beta,22alpha-dihydroxysteroid 3-dehydrogenase [EC:1.14.19.79]
K09589  steroid 3-oxidase [EC:1.14.-.-]
K09827  3-keto steroid reductase [EC:1.1.1.270]
K12420  ketoreductase [EC:1.1.1.-]
K13369  17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.105 1.1.1.239]
K13373  17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270]
K17754  cyclopentanol dehydrogenase [EC:1.1.1.163]
K19960  cyclohexanol dehydrogenase [EC:1.1.1.245]
K27673  trans-4-hydroxycyclohexanecarboxylate dehydrogenase [EC:1.1.1.226]

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