KEGG   PATHWAY: bbub04612
Entry
bbub04612                   Pathway                                
Name
Antigen processing and presentation - Bubalus bubalis (water buffalo)
Class
Organismal Systems; Immune system
Pathway map
bbub04612  Antigen processing and presentation
bbub04612

Other DBs
GO: 0019885 0019886 0042591
Organism
Bubalus bubalis (water buffalo) [GN:bbub]
Gene
102388997  [KO:K10784]
102389065  [KO:K06752]
102389452  [KO:K06516]
102389605  [KO:K06752]
102389823  HSP90AB1; heat shock protein HSP 90-beta [KO:K04079]
102389936  [KO:K06752]
102390270  [KO:K06752]
102390435  [KO:K06751]
102391047  TAP2; antigen peptide transporter 2 [KO:K05654] [EC:7.4.2.14]
102391940  TAP1; antigen peptide transporter 1 isoform X1 [KO:K05653] [EC:7.4.2.14]
102392112  TNF; tumor necrosis factor isoform X1 [KO:K03156]
102392615  [KO:K06751]
102392808  [KO:K06752]
102393133  [KO:K06752]
102393259  RFX5; DNA-binding protein RFX5 [KO:K08061]
102393502  [KO:K03283]
102393680  [KO:K06751]
102393919  RFXANK; DNA-binding protein RFXANK isoform X3 [KO:K08062]
102394284  [KO:K01365] [EC:3.4.22.15]
102394332  [KO:K06751]
102394631  [KO:K06752]
102394968  [KO:K06751]
102396767  PSME2; proteasome activator complex subunit 2 [KO:K06697]
102397070  PSME1; proteasome activator complex subunit 1 [KO:K06696]
102397784  NFYA; nuclear transcription factor Y subunit alpha isoform X7 [KO:K08064]
102398125  [KO:K06751]
102398705  [KO:K08057]
102399346  [KO:K08057]
102399721  CTSL; procathepsin L [KO:K01365] [EC:3.4.22.15]
102399943  [KO:K08058]
102400603  [KO:K07980]
102400671  CD74; HLA class II histocompatibility antigen gamma chain isoform X1 [KO:K06505]
102401072  NFYB; nuclear transcription factor Y subunit beta [KO:K08065]
102401464  [KO:K06698]
102401906  CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
102402080  TAPBPL; tapasin-related protein isoform X1 [KO:K28445]
102402194  HSPA4; heat shock 70 kDa protein 4 [KO:K09489]
102402481  [KO:K06751]
102403157  CIITA; MHC class II transactivator isoform X2 [KO:K08060] [EC:2.7.11.1]
102404744  PSME3; proteasome activator complex subunit 3 isoform X2 [KO:K06698]
102406263  [KO:K06541]
102406400  [KO:K04079]
102406719  [KO:K06751]
102406812  [KO:K06541]
102407115  IFI30; gamma-interferon-inducible lysosomal thiol reductase [KO:K08059]
102407601  [KO:K06752]
102408311  CTSS; cathepsin S [KO:K01368] [EC:3.4.22.27]
102408332  [KO:K03283]
102408568  PDIA3; protein disulfide-isomerase A3 [KO:K08056] [EC:5.3.4.1]
102408905  [KO:K06752]
102409438  [KO:K06752]
102409533  [KO:K03283]
102409598  CD8B; T-cell surface glycoprotein CD8 beta chain [KO:K06459]
102409778  [KO:K06752]
102409833  HSP90AA1; heat shock protein HSP 90-alpha [KO:K04079]
102409928  CD8A; T-cell surface glycoprotein CD8 alpha chain [KO:K06458]
102410738  CTSB; cathepsin B isoform X1 [KO:K01363] [EC:3.4.22.1]
102410871  [KO:K04079]
102410916  [KO:K06751]
102411242  HSPA8; heat shock cognate 71 kDa protein [KO:K03283]
102411392  [KO:K06516]
102411459  HSPA2; heat shock-related 70 kDa protein 2 [KO:K26598]
102411702  LGMN; legumain [KO:K01369] [EC:3.4.22.34]
102411732  [KO:K06516]
102411960  HSPA6; heat shock 70 kDa protein 6 [KO:K03283]
102412126  [KO:K06751]
102412431  HSPA5; endoplasmic reticulum chaperone BiP [KO:K09490] [EC:3.6.4.10]
102412691  [KO:K08063]
102412769  [KO:K06751]
102413610  CALR; calreticulin [KO:K08057]
102413723  CD4; T-cell surface glycoprotein CD4 isoform X1 [KO:K06454]
102413795  CANX; calnexin [KO:K08054]
102413969  [KO:K06751]
102414684  [KO:K06541]
102415309  NFYC; nuclear transcription factor Y subunit gamma isoform X3 [KO:K08066]
102415661  [KO:K06541]
102416494  IFNG; interferon gamma precursor [KO:K04687]
112578753  [KO:K06752]
112584486  [KO:K06541]
112584487  [KO:K06541]
112584489  [KO:K06541]
112587745  [KO:K08055]
112587746  [KO:K08055]
123333201  [KO:K06541]
123464549  [KO:K07980]
123465158  [KO:K07980]
123465160  [KO:K07980]
Reference
PMID:15771591
  Authors
Trombetta ES, Mellman I.
  Title
Cell biology of antigen processing in vitro and in vivo.
  Journal
Annu Rev Immunol 23:975-1028 (2005)
DOI:10.1146/annurev.immunol.22.012703.104538
Reference
PMID:15814328
  Authors
Inaba K, Inaba M.
  Title
Antigen recognition and presentation by dendritic cells.
  Journal
Int J Hematol 81:181-7 (2005)
DOI:10.1532/IJH97.04200
Reference
PMID:11905820
  Authors
Heath WR, Carbone FR.
  Title
Cross-presentation in viral immunity and self-tolerance.
  Journal
Nat Rev Immunol 1:126-34 (2001)
DOI:10.1038/35100512
Reference
PMID:15304636
  Authors
Abele R, Tampe R.
  Title
The ABCs of immunology: structure and function of TAP, the transporter associated with antigen processing.
  Journal
Physiology (Bethesda) 19:216-24 (2004)
DOI:10.1152/physiol.00002.2004
Reference
PMID:16200082
  Authors
Reith W, LeibundGut-Landmann S, Waldburger JM.
  Title
Regulation of MHC class II gene expression by the class II transactivator.
  Journal
Nat Rev Immunol 5:793-806 (2005)
DOI:10.1038/nri1708
Reference
PMID:12776207
  Authors
Honey K, Rudensky AY.
  Title
Lysosomal cysteine proteases regulate antigen presentation.
  Journal
Nat Rev Immunol 3:472-82 (2003)
DOI:10.1038/nri1110
Reference
PMID:12974477
  Authors
Sercarz EE, Maverakis E.
  Title
Mhc-guided processing: binding of large antigen fragments.
  Journal
Nat Rev Immunol 3:621-9 (2003)
DOI:10.1038/nri1149
Reference
PMID:15224093
  Authors
Ackerman AL, Cresswell P.
  Title
Cellular mechanisms governing cross-presentation of exogenous antigens.
  Journal
Nat Immunol 5:678-84 (2004)
DOI:10.1038/ni1082
Reference
PMID:16181333
  Authors
Cresswell P, Ackerman AL, Giodini A, Peaper DR, Wearsch PA.
  Title
Mechanisms of MHC class I-restricted antigen processing and cross-presentation.
  Journal
Immunol Rev 207:145-57 (2005)
DOI:10.1111/j.0105-2896.2005.00316.x
Reference
PMID:15653312
  Authors
Zika E, Ting JP.
  Title
Epigenetic control of MHC-II: interplay between CIITA and histone-modifying enzymes.
  Journal
Curr Opin Immunol 17:58-64 (2005)
DOI:10.1016/j.coi.2004.11.008
Reference
PMID:11244040
  Authors
Reith W, Mach B.
  Title
The bare lymphocyte syndrome and the regulation of MHC expression.
  Journal
Annu Rev Immunol 19:331-73 (2001)
DOI:10.1146/annurev.immunol.19.1.331
Reference
PMID:15745856
  Authors
Lizee G, Basha G, Jefferies WA.
  Title
Tails of wonder: endocytic-sorting motifs key for exogenous antigen presentation.
  Journal
Trends Immunol 26:141-9 (2005)
DOI:10.1016/j.it.2005.01.005
Reference
PMID:15224094
  Authors
Watts C.
  Title
The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules.
  Journal
Nat Immunol 5:685-92 (2004)
DOI:10.1038/ni1088
Reference
PMID:15653315
  Authors
Kaufmann SH, Schaible UE.
  Title
Antigen presentation and recognition in bacterial infections.
  Journal
Curr Opin Immunol 17:79-87 (2005)
DOI:10.1016/j.coi.2004.12.004
Reference
PMID:20010787
  Authors
Groettrup M, Kirk CJ, Basler M
  Title
Proteasomes in immune cells: more than peptide producers?
  Journal
Nat Rev Immunol 10:73-8 (2010)
DOI:10.1038/nri2687
Related
pathway
bbub03050  Proteasome
bbub04650  Natural killer cell mediated cytotoxicity
bbub04660  T cell receptor signaling pathway
KO pathway
ko04612   

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