KEGG   PATHWAY: bsep00230
Entry
bsep00230                   Pathway                                
Name
Purine metabolism - Bradyrhizobium septentrionale
Class
Metabolism; Nucleotide metabolism
Pathway map
bsep00230  Purine metabolism
bsep00230

Module
bsep_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:bsep00230]
bsep_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:bsep00230]
bsep_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:bsep00230]
bsep_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:bsep00230]
bsep_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:bsep00230]
bsep_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:bsep00230]
Other DBs
GO: 0006163 0042278
Organism
Bradyrhizobium septentrionale [GN:bsep]
Gene
HAP48_0025395  pgm; phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) [KO:K01835] [EC:5.4.2.2]
HAP48_0012820  phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
HAP48_0001750  ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
HAP48_0022485  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
HAP48_0035875  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
HAP48_0022185  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
HAP48_0036140  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
HAP48_0046225  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
HAP48_0046290  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
HAP48_0046280  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
HAP48_0036135  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
HAP48_0009295  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
HAP48_0009290  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
HAP48_0046295  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
HAP48_0016455  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
HAP48_0046040  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
HAP48_0014970  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
HAP48_0006790  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
HAP48_0028980  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
HAP48_0039100  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
HAP48_0022500  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
HAP48_0035345  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
HAP48_0036100  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
HAP48_0015610  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
HAP48_0045625  gpt; xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
HAP48_0026045  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
HAP48_0026040  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
HAP48_0022745  FAD binding domain-containing protein [KO:K11178] [EC:1.17.1.4]
HAP48_0026035  2Fe-2S iron-sulfur cluster-binding protein [KO:K13483]
HAP48_0035410  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
HAP48_0014765  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
HAP48_0036010  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
HAP48_0024660  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
HAP48_0036660  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
HAP48_0038465  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
HAP48_0004525  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
HAP48_0011020  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
HAP48_0024665  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
HAP48_0038460  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
HAP48_0004530  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
HAP48_0011025  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
HAP48_0039155  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
HAP48_0003335  HD family hydrolase [KO:K06952] [EC:3.1.3.89]
HAP48_0041585  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
HAP48_0035295  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
HAP48_0036115  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
HAP48_0025535  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
HAP48_0028925  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
HAP48_0033555  HAMP domain-containing protein [KO:K01768] [EC:4.6.1.1]
HAP48_0041505  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
HAP48_0044495  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
HAP48_0045850  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
HAP48_0046075  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
HAP48_0002365  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
HAP48_0009375  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
HAP48_0017120  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
HAP48_0018605  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
HAP48_0013425  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
HAP48_0008530  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
HAP48_0045765  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
HAP48_0020720  TIGR00282 family metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
HAP48_0043830  adenylate kinase [KO:K00939] [EC:2.7.4.3]
HAP48_0048510  adenylate kinase [KO:K00939] [EC:2.7.4.3]
HAP48_0037720  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
HAP48_0047440  phosphodiesterase [KO:K03651] [EC:3.1.4.53]
HAP48_0047845  phosphodiesterase [KO:K03651] [EC:3.1.4.53]
HAP48_0020060  cysC; adenylyl-sulfate kinase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
HAP48_0005625  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
HAP48_0020065  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
HAP48_0008120  SidA/IucD/PvdA family monooxygenase [KO:K22879] [EC:1.14.13.113]
HAP48_0018245  aspartate/glutamate racemase family protein [KO:K16841] [EC:5.1.99.3]
HAP48_0029240  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
HAP48_0029270  allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
HAP48_0019875  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
HAP48_0019865  urease subunit beta [KO:K01429] [EC:3.5.1.5]
HAP48_0019860  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
bsep00030  Pentose phosphate pathway
bsep00220  Arginine biosynthesis
bsep00250  Alanine, aspartate and glutamate metabolism
bsep00260  Glycine, serine and threonine metabolism
bsep00340  Histidine metabolism
bsep00630  Glyoxylate and dicarboxylate metabolism
bsep00730  Thiamine metabolism
bsep00740  Riboflavin metabolism
bsep00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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