KEGG   PATHWAY: bta00513
Entry
bta00513                    Pathway                                
Name
Various types of N-glycan biosynthesis - Bos taurus (cow)
Class
Metabolism; Glycan biosynthesis and metabolism
Pathway map
bta00513  Various types of N-glycan biosynthesis
bta00513

Module
bta_M00072  N-glycosylation by oligosaccharyltransferase [PATH:bta00513]
Other DBs
GO: 0006487
Organism
Bos taurus (cow) [GN:bta]
Gene
100125314  ALG12; dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase precursor [KO:K03847] [EC:2.4.1.260]
100125390  B4GALT2; beta-1,4-galactosyltransferase 2 [KO:K07967] [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
100137759  B4GALNT4; N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 isoform X1 [KO:K09657] [EC:2.4.1.244]
100271926  CHST8; carbohydrate sulfotransferase 8 [KO:K09672] [EC:2.8.2.-]
100301169  MAGT1; magnesium transporter protein 1 precursor [KO:K19478]
100336900  [KO:K23741]
101906103  MGAT2; alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase [KO:K00736] [EC:2.4.1.143]
101907024  MGAT4D; alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D isoform X1 [KO:K00738] [EC:2.4.1.145]
107131137  MAN1B1; endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase isoform X2 [KO:K23741]
107132045  [KO:K07432] [EC:2.4.1.141]
281177  FUT8; alpha-(1,6)-fucosyltransferase [KO:K00717] [EC:2.4.1.68]
281781  B4GALT1; beta-1,4-galactosyltransferase 1 [KO:K07966] [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-]
282276  MGAT4A; alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A [KO:K00738] [EC:2.4.1.145]
444859  ST3GAL3; CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase [KO:K00781] [EC:2.4.3.6]
504346  ALG9; alpha-1,2-mannosyltransferase ALG9 isoform X1 [KO:K03846] [EC:2.4.1.259 2.4.1.261]
504468  HEXA; beta-hexosaminidase subunit alpha precursor [KO:K12373] [EC:3.2.1.52]
504474  STT3B; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B [KO:K07151] [EC:2.4.99.18]
506184  HEXD; hexosaminidase D [KO:K14459] [EC:3.2.1.52]
506537  ALG14; UDP-N-acetylglucosamine transferase subunit ALG14 homolog [KO:K07441] [EC:2.4.1.141]
507210  ALG1; chitobiosyldiphosphodolichol beta-mannosyltransferase precursor [KO:K03842] [EC:2.4.1.142]
507815  STT3A; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A [KO:K07151] [EC:2.4.99.18]
507939  RPN1; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 precursor [KO:K12666]
510682  DDOST; dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit precursor [KO:K12670]
515282  ALG13; putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 isoform X1 [KO:K07432] [EC:2.4.1.141]
515771  B4GALT3; beta-1,4-galactosyltransferase 3 [KO:K07968] [EC:2.4.1.90 2.4.1.38 2.4.1.-]
521539  MAN2A1; alpha-mannosidase 2 [KO:K01231] [EC:3.2.1.114]
525909  CHST9; carbohydrate sulfotransferase 9 [KO:K09673] [EC:2.8.2.-]
526256  MGAT4B; alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B precursor [KO:K00738] [EC:2.4.1.145]
527026  B4GALNT3; beta-1,4-N-acetylgalactosaminyltransferase 3 [KO:K09656] [EC:2.4.1.244]
527449  MAN2A2; alpha-mannosidase 2x [KO:K01231] [EC:3.2.1.114]
530027  MAN1A1; mannosyl-oligosaccharide 1,2-alpha-mannosidase IA [KO:K01230] [EC:3.2.1.113]
532645  MAN1A2; mannosyl-oligosaccharide 1,2-alpha-mannosidase IB [KO:K01230] [EC:3.2.1.113]
534231  RPN2; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 precursor [KO:K12667]
534248  MGAT1; alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase [KO:K00726] [EC:2.4.1.101]
538899  ALG2; alpha-1,3/1,6-mannosyltransferase ALG2 [KO:K03843] [EC:2.4.1.132 2.4.1.257]
539661  MGAT4C; alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C [KO:K13748] [EC:2.4.1.201 2.4.1.145]
539818  [KO:K12666]
540389  KRTCAP2; keratinocyte-associated protein 2 [KO:K28202]
540845  ALG11; GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase [KO:K03844] [EC:2.4.1.131]
614538  DAD1; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 [KO:K12668]
614624  ALG3; dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase [KO:K03845] [EC:2.4.1.258]
615007  TUSC3; tumor suppressor candidate 3 precursor [KO:K19478]
615012  MAN1C1; mannosyl-oligosaccharide 1,2-alpha-mannosidase IC isoform X1 [KO:K01230] [EC:3.2.1.113]
618571  HEXB; beta-hexosaminidase subunit beta preproprotein [KO:K12373] [EC:3.2.1.52]
767958  TMEM258; transmembrane protein 258 [KO:K26502]
768033  OSTC; oligosaccharyltransferase complex subunit OSTC [KO:K26501]
786974  [KO:K12373] [EC:3.2.1.52]
Compound
G00011  
G00012  
G00013  
G00014  
G00015  
G00016  Core fucose
G00017  
G00179  
G01813  
G05477  
G10665  
G10694  
G10716  
G10770  
G10841  
G10920  
G11000  
G11040  
G11933  
G12617  
G12625  
G12626  
G13047  
G13048  
G13049  
G13050  
G13055  
G13056  
G13057  
G13058  
G13059  
Reference
PMID:11412862
  Authors
Munro S.
  Title
What can yeast tell us about N-linked glycosylation in the Golgi apparatus?
  Journal
FEBS Lett 498:223-7 (2001)
DOI:10.1016/S0014-5793(01)02488-7
Reference
PMID:9878803
  Authors
Dean N.
  Title
Asparagine-linked glycosylation in the yeast Golgi.
  Journal
Biochim Biophys Acta 1426:309-22 (1999)
DOI:10.1016/S0304-4165(98)00132-9
Reference
PMID:9878780
  Authors
Herscovics A.
  Title
Processing glycosidases of Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1426:275-85 (1999)
DOI:10.1016/S0304-4165(98)00129-9
Reference
PMID:9218445
  Authors
Wang XH, Nakayama K, Shimma Y, Tanaka A, Jigami Y.
  Title
MNN6, a member of the KRE2/MNT1 family, is the gene for mannosylphosphate transfer in Saccharomyces cerevisiae.
  Journal
J Biol Chem 272:18117-24 (1997)
DOI:10.1074/jbc.272.29.18117
Reference
PMID:9756928
  Authors
Rayner JC, Munro S.
  Title
Identification of the MNN2 and MNN5 mannosyltransferases required for forming and extending the mannose branches of the outer chain mannans of Saccharomyces cerevisiae.
  Journal
J Biol Chem 273:26836-43 (1998)
DOI:10.1074/jbc.273.41.26836
Reference
PMID:10037752
  Authors
Jungmann J, Rayner JC, Munro S.
  Title
The Saccharomyces cerevisiae protein Mnn10p/Bed1p is a subunit of a Golgi mannosyltransferase complex.
  Journal
J Biol Chem 274:6579-85 (1999)
DOI:10.1074/jbc.274.10.6579
Reference
PMID:8253757
  Authors
Nakanishi-Shindo Y, Nakayama K, Tanaka A, Toda Y, Jigami Y.
  Title
Structure of the N-linked oligosaccharides that show the complete loss of alpha-1,6-polymannose outer chain from och1, och1 mnn1, and och1 mnn1 alg3 mutants of Saccharomyces cerevisiae.
  Journal
J Biol Chem 268:26338-45 (1993)
Reference
PMID:20233335
  Authors
Gomord V, Fitchette AC, Menu-Bouaouiche L, Saint-Jore-Dupas C, Plasson C, Michaud D, Faye L
  Title
Plant-specific glycosylation patterns in the context of therapeutic protein production.
  Journal
Plant Biotechnol J 8:564-87 (2010)
DOI:10.1111/j.1467-7652.2009.00497.x
Related
pathway
bta00510  N-Glycan biosynthesis
KO pathway
ko00513   

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