KEGG   PATHWAY: cfir00230
Entry
cfir00230                   Pathway                                
Name
Purine metabolism - Cytobacillus firmus
Class
Metabolism; Nucleotide metabolism
Pathway map
cfir00230  Purine metabolism
cfir00230

Module
cfir_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:cfir00230]
cfir_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:cfir00230]
cfir_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:cfir00230]
cfir_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:cfir00230]
cfir_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:cfir00230]
Other DBs
GO: 0006163 0042278
Organism
Cytobacillus firmus [GN:cfir]
Gene
NAF01_17980  NUDIX hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
NAF01_22775  NUDIX hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
NAF01_17945  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
NAF01_23470  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
NAF01_06200  phospho-sugar mutase [KO:K01835] [EC:5.4.2.2]
NAF01_22835  phospho-sugar mutase [KO:K01835] [EC:5.4.2.2]
NAF01_00310  ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
NAF01_01820  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
NAF01_01840  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
NAF01_01830  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
NAF01_01815  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
NAF01_01805  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
NAF01_01810  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
NAF01_01825  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
NAF01_01790  purK; 5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
NAF01_01785  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
NAF01_01800  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
NAF01_01795  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
NAF01_01835  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
NAF01_19235  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
NAF01_02685  5'-nucleotidase C-terminal domain-containing protein [KO:K01081] [EC:3.1.3.5]
NAF01_17940  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
NAF01_16745  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
NAF01_08780  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
NAF01_03285  nucleoside hydrolase [KO:K01239] [EC:3.2.2.1]
NAF01_16490  nucleoside hydrolase [KO:K01239] [EC:3.2.2.1]
NAF01_16900  nucleoside hydrolase [KO:K01239] [EC:3.2.2.1]
NAF01_00405  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
NAF01_00075  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
NAF01_17565  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
NAF01_20300  DUF84 family protein [KO:K01529] [EC:3.6.1.73]
NAF01_19650  XTP/dITP diphosphatase [KO:K01519] [EC:3.6.1.66]
NAF01_17205  xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
NAF01_11030  molybdopterin-dependent oxidoreductase [KO:K00087] [EC:1.17.1.4]
NAF01_14300  XdhC family protein [KO:K00087] [EC:1.17.1.4]
NAF01_01740  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
NAF01_10070  guaC; GMP reductase [KO:K00364] [EC:1.7.1.7]
NAF01_14005  guaC; GMP reductase [KO:K00364] [EC:1.7.1.7]
NAF01_24550  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
NAF01_15105  nucleoside deaminase [KO:K01487] [EC:3.5.4.3]
NAF01_08900  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
NAF01_16385  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
NAF01_18395  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
NAF01_16380  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
NAF01_00110  deoxynucleoside kinase [KO:K15518] [EC:2.7.1.113]
NAF01_19230  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
NAF01_07320  GTP pyrophosphokinase family protein [KO:K07816] [EC:2.7.6.5]
NAF01_12875  GTP pyrophosphokinase family protein [KO:K07816] [EC:2.7.6.5]
NAF01_24785  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
NAF01_00105  deoxynucleoside kinase [KO:K15519] [EC:2.7.1.76 2.7.1.74]
NAF01_09980  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
NAF01_01850  amidohydrolase family protein [KO:K01486] [EC:3.5.4.2]
NAF01_11010  ade; adenine deaminase [KO:K01486] [EC:3.5.4.2]
NAF01_11110  amidohydrolase family protein [KO:K01486] [EC:3.5.4.2]
NAF01_08020  bifunctional metallophosphatase/5'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
NAF01_11985  metallophosphoesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
NAF01_04870  bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase [KO:K08693] [EC:3.1.4.16 3.1.3.6 3.1.3.5]
NAF01_22975  bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase [KO:K08693] [EC:3.1.4.16 3.1.3.6 3.1.3.5]
NAF01_09590  TIGR00282 family metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
NAF01_00805  adenylate kinase [KO:K00939] [EC:2.7.4.3]
NAF01_12375  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
NAF01_12530  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
NAF01_12380  sat; sulfate adenylyltransferase [KO:K00958] [EC:2.7.7.4]
NAF01_12535  sat; sulfate adenylyltransferase [KO:K00958] [EC:2.7.7.4]
NAF01_05525  allB; allantoinase AllB [KO:K01466] [EC:3.5.2.5]
NAF01_03270  Zn-dependent hydrolase [KO:K02083] [EC:3.5.3.9]
NAF01_04490  M20 family metallo-hydrolase [KO:K02083] [EC:3.5.3.9]
NAF01_05530  allC; allantoate deiminase [KO:K02083] [EC:3.5.3.9]
NAF01_05535  allE; (S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
cfir00030  Pentose phosphate pathway
cfir00220  Arginine biosynthesis
cfir00250  Alanine, aspartate and glutamate metabolism
cfir00260  Glycine, serine and threonine metabolism
cfir00340  Histidine metabolism
cfir00630  Glyoxylate and dicarboxylate metabolism
cfir00730  Thiamine metabolism
cfir00740  Riboflavin metabolism
cfir00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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